PT1104297E - Composicoes para o tratamento da leucemia linfocitica cronica - Google Patents

Composicoes para o tratamento da leucemia linfocitica cronica

Info

Publication number
PT1104297E
PT1104297E PT99937222T PT99937222T PT1104297E PT 1104297 E PT1104297 E PT 1104297E PT 99937222 T PT99937222 T PT 99937222T PT 99937222 T PT99937222 T PT 99937222T PT 1104297 E PT1104297 E PT 1104297E
Authority
PT
Portugal
Prior art keywords
lymphocytic leukemia
chronic lymphocytic
compositions
treatment
compounds
Prior art date
Application number
PT99937222T
Other languages
English (en)
Portuguese (pt)
Inventor
Francis A Nardella
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of PT1104297E publication Critical patent/PT1104297E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PT99937222T 1998-07-09 1999-07-08 Composicoes para o tratamento da leucemia linfocitica cronica PT1104297E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9246698P 1998-07-09 1998-07-09
US9487898P 1998-07-29 1998-07-29

Publications (1)

Publication Number Publication Date
PT1104297E true PT1104297E (pt) 2006-05-31

Family

ID=26785713

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99937222T PT1104297E (pt) 1998-07-09 1999-07-08 Composicoes para o tratamento da leucemia linfocitica cronica

Country Status (12)

Country Link
US (3) US6573292B1 (https=)
EP (1) EP1104297B8 (https=)
JP (1) JP2002520282A (https=)
AT (1) ATE315392T1 (https=)
AU (1) AU767586B2 (https=)
CA (1) CA2336932A1 (https=)
DE (1) DE69929440T2 (https=)
DK (1) DK1104297T3 (https=)
ES (1) ES2255287T3 (https=)
NZ (1) NZ509376A (https=)
PT (1) PT1104297E (https=)
WO (1) WO2000002555A1 (https=)

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US7129262B2 (en) 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US6545034B1 (en) 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US7361680B2 (en) 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
WO2004026116A2 (en) 2002-09-19 2004-04-01 The Regents Of The University Of California Use of etodoclac to treat hyperplasia
CA2540289A1 (en) * 2003-10-02 2005-04-14 Cephalon, Inc. Substituted indole derivatives
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US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
EP2294186B1 (en) * 2008-05-20 2019-10-09 Incuron, Inc. Inducing cell death by inhibiting adaptive heat shock response
EP2326306A1 (en) 2008-09-25 2011-06-01 Cephalon, Inc. Liquid formulations of bendamustine
NZ594010A (en) * 2009-01-15 2013-08-30 Cephalon Inc Novel forms of bendamustine free base
CN107441493A (zh) 2010-08-18 2017-12-08 德玛医药 制备用于改善未达最佳给药药物治疗的有效性和/或减少其副作用的药物的方法
US12194002B2 (en) 2011-08-17 2025-01-14 Dennis Brown Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dibromodulcitol
BR112014017833A2 (pt) 2012-01-20 2021-03-23 Dennis Brown Uso de hexitóis substituídos incluindo dianidrogalactitol e análogos para tratar doença neoplástica e células-tronco de câncer incluindo glioblastoma multiforme e meduloblastoma
US20150087687A1 (en) 2012-03-23 2015-03-26 Dennis Brown Compositions and methods to improve the therapeutic benefit of indirubin and analogs thereof, including meisoindigo
US9814693B2 (en) 2012-05-09 2017-11-14 Delmar Pharmaceuticals, Inc. Veterinary use of dianhydrogalactitol, diacetyldianhydrogalactitol, and dibromodulcitol to treat malignancies
JP6280546B2 (ja) 2012-06-26 2018-02-14 デル マー ファーマシューティカルズ ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はａｈｉ１の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法
KR102359214B1 (ko) 2014-04-04 2022-02-07 델 마 파마슈티컬스 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체
CN106572992A (zh) 2014-04-06 2017-04-19 英丘伦有限责任公司 用curaxins进行组合治疗
AU2017260706B2 (en) 2016-05-04 2023-05-11 Inmed Pharmaceuticals Inc. Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders
EP3684353A4 (en) 2017-09-22 2021-06-23 Inmed Pharmaceuticals Inc. TOPICAL FORMULATIONS OF CANNABINOIDS AND THEIR USES FOR PAIN TREATMENT

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Also Published As

Publication number Publication date
AU5209899A (en) 2000-02-01
US20030232874A1 (en) 2003-12-18
EP1104297A1 (en) 2001-06-06
JP2002520282A (ja) 2002-07-09
US6573292B1 (en) 2003-06-03
US6921772B2 (en) 2005-07-26
ATE315392T1 (de) 2006-02-15
AU767586B2 (en) 2003-11-20
EP1104297A4 (en) 2003-01-02
CA2336932A1 (en) 2000-01-20
ES2255287T3 (es) 2006-06-16
DE69929440D1 (de) 2006-04-06
DK1104297T3 (da) 2006-05-29
WO2000002555A1 (en) 2000-01-20
EP1104297B1 (en) 2006-01-11
US20050261356A1 (en) 2005-11-24
EP1104297B8 (en) 2006-05-03
NZ509376A (en) 2003-10-31
DE69929440T2 (de) 2006-08-17

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