PT1047422E - Utilizacao de histamina para elevar os niveis de histamina no sangue - Google Patents

Utilizacao de histamina para elevar os niveis de histamina no sangue

Info

Publication number
PT1047422E
PT1047422E PT98957777T PT98957777T PT1047422E PT 1047422 E PT1047422 E PT 1047422E PT 98957777 T PT98957777 T PT 98957777T PT 98957777 T PT98957777 T PT 98957777T PT 1047422 E PT1047422 E PT 1047422E
Authority
PT
Portugal
Prior art keywords
histamine
levels
methods
natural killer
killer cell
Prior art date
Application number
PT98957777T
Other languages
English (en)
Inventor
Kristoffer Hellstrand
Hermodsson Svante
Kurt R Gehlsen
Original Assignee
Maxim Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maxim Pharm Inc filed Critical Maxim Pharm Inc
Publication of PT1047422E publication Critical patent/PT1047422E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/417Imidazole-alkylamines, e.g. histamine, phentolamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Road Signs Or Road Markings (AREA)
  • Ladders (AREA)
  • Saccharide Compounds (AREA)
PT98957777T 1997-11-13 1998-11-10 Utilizacao de histamina para elevar os niveis de histamina no sangue PT1047422E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/969,384 US6071942A (en) 1996-05-14 1997-11-13 Elevation of circulating blood histamine levels

Publications (1)

Publication Number Publication Date
PT1047422E true PT1047422E (pt) 2006-05-31

Family

ID=25515502

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98957777T PT1047422E (pt) 1997-11-13 1998-11-10 Utilizacao de histamina para elevar os niveis de histamina no sangue

Country Status (15)

Country Link
US (2) US6071942A (pt)
EP (1) EP1047422B1 (pt)
JP (1) JP2001522885A (pt)
KR (1) KR20010031979A (pt)
CN (1) CN1128618C (pt)
AT (1) ATE315393T1 (pt)
AU (1) AU760068B2 (pt)
CA (1) CA2310255A1 (pt)
DE (1) DE69833225T2 (pt)
DK (1) DK1047422T3 (pt)
ES (1) ES2256971T3 (pt)
HK (1) HK1035330A1 (pt)
IL (1) IL135872A0 (pt)
PT (1) PT1047422E (pt)
WO (1) WO1999025341A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6242473B1 (en) * 1999-01-08 2001-06-05 Maxim Pharmaceuticals, Inc. Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
PT1187611E (pt) * 1999-06-03 2004-10-29 Maxim Pharm Inc Composicoes oftalmicas de histamina e sua utilizacoes
CN1571674A (zh) * 2001-10-19 2005-01-26 马克西姆医药公司 组胺治疗肝疾病的用途
US20030143195A1 (en) * 2002-01-30 2003-07-31 Pinsker Judy Senior Use of histamine as a drug delivery enhancing compound for use in transmucosal or transdermal delivery
AP2007003939A0 (en) * 2004-09-03 2007-04-30 Prometic Biosciences Inc Substituted purinyl derivatives with immunomodulator and chemoprotective activity and use alone or with medium-chain length fatty acids or glycerides
WO2014088641A1 (en) * 2012-12-05 2014-06-12 Biohealthonomics Inc. Methods for restoration of histamine balance
US9023881B2 (en) 2012-12-05 2015-05-05 Biohealthonomics Inc. Methods for restoration of histamine balance
US10117908B2 (en) 2013-10-17 2018-11-06 Grant Labs, Inc. Suppression of cellular transformation and dysplasia by topical application of lefty

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1911429A1 (de) * 1969-03-06 1970-09-24 Waldhof Zellstoff Fab Lipophile Puryl-(6)-histaminderivate und Verfahren zu ihrer Herstellung
US4849329A (en) * 1986-05-30 1989-07-18 E. I. Du Pont De Nemours And Company Process for preparing lymphokine activated killer cells
ES2087163T3 (es) * 1989-09-19 1996-07-16 Syntello Inc Preparacion antitumoral que comprende intreleucina-2 e histamina, analogo al de las mismas o agonistas de receptor h2.
US5135491A (en) * 1990-11-02 1992-08-04 Baldwin Brian E Patient controlled infusion apparatus and method
WO1993020803A1 (en) * 1992-04-22 1993-10-28 Molecular Rx, Inc. Method and composition for the treatment of disorders involving immunological dysfunction
SE513429C2 (sv) * 1992-06-03 2000-09-11 Syntello Inc Preparat för aktivering av naturliga mördarceller, vilket preparat innehåller interferon alfa och biogena aminer
US5843979A (en) * 1993-02-25 1998-12-01 Bristol-Myers Squibb Company Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity
JP3193205B2 (ja) * 1993-08-09 2001-07-30 日本臓器製薬株式会社 好酸球増多抑制剤
JPH07165582A (ja) * 1993-12-08 1995-06-27 Seiji Takayama 免疫抗癌剤の抗癌効果増強剤
US5478211A (en) * 1994-03-09 1995-12-26 Baxter International Inc. Ambulatory infusion pump
WO1996005289A1 (en) * 1994-08-08 1996-02-22 Syntello, Inc. Enhanced activation of natural killer cells using an nk cell activator and a hydrogen peroxide scavenger or inhibitor
US5961969A (en) * 1996-05-14 1999-10-05 Maxim Pharmaceuticals, Inc. Stable circulating histamine levels

Also Published As

Publication number Publication date
EP1047422A1 (en) 2000-11-02
KR20010031979A (ko) 2001-04-16
CN1128618C (zh) 2003-11-26
DE69833225T2 (de) 2006-08-10
US6071942A (en) 2000-06-06
ES2256971T3 (es) 2006-07-16
DK1047422T3 (da) 2006-04-18
DE69833225D1 (de) 2006-04-06
US6613788B1 (en) 2003-09-02
CN1285744A (zh) 2001-02-28
AU1395599A (en) 1999-06-07
HK1035330A1 (en) 2001-11-23
WO1999025341A1 (en) 1999-05-27
IL135872A0 (en) 2001-05-20
ATE315393T1 (de) 2006-02-15
EP1047422B1 (en) 2006-01-11
JP2001522885A (ja) 2001-11-20
CA2310255A1 (en) 1999-05-27
AU760068B2 (en) 2003-05-08

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