PT101065B - Sequencias de adn e vectores que codificam carminomicina-4-0-metil-transferase e processo para a preparacao de daunorrubicina - Google Patents

Sequencias de adn e vectores que codificam carminomicina-4-0-metil-transferase e processo para a preparacao de daunorrubicina Download PDF

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Publication number
PT101065B
PT101065B PT101065A PT10106592A PT101065B PT 101065 B PT101065 B PT 101065B PT 101065 A PT101065 A PT 101065A PT 10106592 A PT10106592 A PT 10106592A PT 101065 B PT101065 B PT 101065B
Authority
PT
Portugal
Prior art keywords
carminomycin
dna
gene
daunorubicin
dnrk
Prior art date
Application number
PT101065A
Other languages
English (en)
Portuguese (pt)
Other versions
PT101065A (pt
Inventor
Anna Luisa Colombo
Francesca Torti
Charles Richard Hutchinson
Krishna Murthy Madduri
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of PT101065A publication Critical patent/PT101065A/pt
Publication of PT101065B publication Critical patent/PT101065B/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/888—Streptomyces antibioticus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PT101065A 1991-11-18 1992-11-16 Sequencias de adn e vectores que codificam carminomicina-4-0-metil-transferase e processo para a preparacao de daunorrubicina PT101065B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79387391A 1991-11-18 1991-11-18

Publications (2)

Publication Number Publication Date
PT101065A PT101065A (pt) 1994-02-28
PT101065B true PT101065B (pt) 1999-08-31

Family

ID=25161036

Family Applications (1)

Application Number Title Priority Date Filing Date
PT101065A PT101065B (pt) 1991-11-18 1992-11-16 Sequencias de adn e vectores que codificam carminomicina-4-0-metil-transferase e processo para a preparacao de daunorrubicina

Country Status (7)

Country Link
US (1) US5364781A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100283826B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT101065B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (2) RU2155811C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW227575B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UA (1) UA39922C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA928865B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ245124A (en) * 1991-11-18 1994-06-27 Erba Carlo Spa Carminomycin 4-0-methyltransferase, dna encoding it, vectors and host cells; and also a process for producing daunorubicin
FI944556A0 (fi) * 1994-09-30 1994-09-30 Kristiina Ylihonko Foerfarande foer producering av antracykliner och deras mellanprodukter
GB2302540B (en) * 1995-06-23 1999-02-24 Pharmacia Spa Cofactor for transmethylation
US5652125A (en) * 1996-06-10 1997-07-29 Pharmacia S.P.A. Process for preparing daunorubicin
DE19880405T1 (de) * 1997-03-06 1999-11-11 Pharmacia & Upjohn Spa Verfahren zur Herstellung von Doxorubicin
EP1071746A4 (en) * 1998-04-24 2003-04-23 Pharmacia Italia Spa METHOD FOR PRODUCING DOXORUBICIN
US6177262B1 (en) * 1998-09-22 2001-01-23 Kosan Biosciences, Inc. Recombinant host cells for the production of polyketides
KR102080666B1 (ko) * 2019-04-12 2020-02-24 박행제 수력발전장치용 임펠라 어셈블리

Also Published As

Publication number Publication date
KR100283826B1 (ko) 2001-03-02
ZA928865B (en) 1993-05-13
TW227575B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1994-08-01
RU2115731C1 (ru) 1998-07-20
UA39922C2 (uk) 2001-07-16
RU2155811C2 (ru) 2000-09-10
PT101065A (pt) 1994-02-28
US5364781A (en) 1994-11-15

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Effective date: 19930810

FG3A Patent granted, date of granting

Effective date: 19990505

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20071105