PL97192B1 - Sposob wytwarzania nowych pochodnych chinoliny - Google Patents
Sposob wytwarzania nowych pochodnych chinoliny Download PDFInfo
- Publication number
- PL97192B1 PL97192B1 PL18726074A PL18726074A PL97192B1 PL 97192 B1 PL97192 B1 PL 97192B1 PL 18726074 A PL18726074 A PL 18726074A PL 18726074 A PL18726074 A PL 18726074A PL 97192 B1 PL97192 B1 PL 97192B1
- Authority
- PL
- Poland
- Prior art keywords
- chinoline
- new derivatives
- compounds
- making new
- general formula
- Prior art date
Links
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical class N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 125000000217 alkyl group Chemical group 0.000 claims description 6
- 150000003839 salts Chemical class 0.000 claims description 5
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 3
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 claims description 2
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 claims description 2
- 125000002252 acyl group Chemical group 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- -1 2-propyl-5-amino-5-pyrimidyl-methyl Chemical group 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- 238000003776 cleavage reaction Methods 0.000 description 3
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 3
- 235000015497 potassium bicarbonate Nutrition 0.000 description 3
- 239000011736 potassium bicarbonate Substances 0.000 description 3
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 3
- 230000007017 scission Effects 0.000 description 3
- 238000009835 boiling Methods 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- JHAYEQICABJSTP-UHFFFAOYSA-N decoquinate Chemical compound N1C=C(C(=O)OCC)C(=O)C2=C1C=C(OCC)C(OCCCCCCCCCC)=C2 JHAYEQICABJSTP-UHFFFAOYSA-N 0.000 description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- YSEYOMUPVMGJPP-UHFFFAOYSA-N 3-chloro-2-methylpyridine Chemical compound CC1=NC=CC=C1Cl YSEYOMUPVMGJPP-UHFFFAOYSA-N 0.000 description 1
- 150000004333 6-hydroxyquinolines Chemical class 0.000 description 1
- 102220480121 H/ACA ribonucleoprotein complex subunit DKC1_R10A_mutation Human genes 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical class Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 description 1
- 229930194542 Keto Natural products 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229960003683 amprolium Drugs 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 150000001733 carboxylic acid esters Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 229960001878 decoquinate Drugs 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 150000002085 enols Chemical class 0.000 description 1
- 125000004185 ester group Chemical group 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- GLUQMYQDGHKVIX-UHFFFAOYSA-N ethyl 7-ethoxy-6-hydroxy-4-oxo-1h-quinoline-3-carboxylate Chemical compound CCOC1=C(O)C=C2C(=O)C(C(=O)OCC)=CNC2=C1 GLUQMYQDGHKVIX-UHFFFAOYSA-N 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- PJBQYZZKGNOKNJ-UHFFFAOYSA-M hydron;5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propylpyrimidin-4-amine;dichloride Chemical compound Cl.[Cl-].NC1=NC(CCC)=NC=C1C[N+]1=CC=CC=C1C PJBQYZZKGNOKNJ-UHFFFAOYSA-M 0.000 description 1
- 125000000468 ketone group Chemical group 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229940086066 potassium hydrogencarbonate Drugs 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 150000003248 quinolines Chemical class 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI001403 HU167572B (enExample) | 1973-08-28 | 1973-08-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL97192B1 true PL97192B1 (pl) | 1978-02-28 |
Family
ID=10994490
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18726074A PL97192B1 (pl) | 1973-08-28 | 1974-08-26 | Sposob wytwarzania nowych pochodnych chinoliny |
| PL17367974A PL99024B1 (pl) | 1973-08-28 | 1974-08-26 | Sposob wytwarzania nowych pochodnych chinoliny |
| PL18726274A PL97191B1 (pl) | 1973-08-28 | 1974-08-26 | Sposob wytwarzania nowych pochodnych chinoliny |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17367974A PL99024B1 (pl) | 1973-08-28 | 1974-08-26 | Sposob wytwarzania nowych pochodnych chinoliny |
| PL18726274A PL97191B1 (pl) | 1973-08-28 | 1974-08-26 | Sposob wytwarzania nowych pochodnych chinoliny |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS5843953A (enExample) |
| HU (1) | HU167572B (enExample) |
| PL (3) | PL97192B1 (enExample) |
-
1973
- 1973-08-28 HU HUCI001403 patent/HU167572B/hu unknown
-
1974
- 1974-08-26 PL PL18726074A patent/PL97192B1/pl unknown
- 1974-08-26 PL PL17367974A patent/PL99024B1/pl unknown
- 1974-08-26 PL PL18726274A patent/PL97191B1/pl unknown
-
1982
- 1982-07-30 JP JP13360782A patent/JPS5843953A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PL97191B1 (pl) | 1978-02-28 |
| HU167572B (enExample) | 1975-11-28 |
| JPS5843953A (ja) | 1983-03-14 |
| PL99024B1 (pl) | 1978-06-30 |
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