PL378416A1 - Różnie podstawione pochodne guanidyny i ich zastosowanie jako leki o aktywności przeciwcukrzycowej i/lub przeciw otyłości - Google Patents

Różnie podstawione pochodne guanidyny i ich zastosowanie jako leki o aktywności przeciwcukrzycowej i/lub przeciw otyłości

Info

Publication number
PL378416A1
PL378416A1 PL378416A PL37841603A PL378416A1 PL 378416 A1 PL378416 A1 PL 378416A1 PL 378416 A PL378416 A PL 378416A PL 37841603 A PL37841603 A PL 37841603A PL 378416 A1 PL378416 A1 PL 378416A1
Authority
PL
Poland
Prior art keywords
guanidine
medicines
diabetes
substituted derivatives
variously substituted
Prior art date
Application number
PL378416A
Other languages
English (en)
Polish (pl)
Inventor
Fabio Giannessi
Emanuela Tassoni
Maria Ornella Tinti
Pompeo Pessotto
Maurizio Botta
Federico Corelli
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of PL378416A1 publication Critical patent/PL378416A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
PL378416A 2002-12-17 2003-12-01 Różnie podstawione pochodne guanidyny i ich zastosowanie jako leki o aktywności przeciwcukrzycowej i/lub przeciw otyłości PL378416A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000625A ITRM20020625A1 (it) 2002-12-17 2002-12-17 Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'.

Publications (1)

Publication Number Publication Date
PL378416A1 true PL378416A1 (pl) 2006-04-03

Family

ID=32587901

Family Applications (1)

Application Number Title Priority Date Filing Date
PL378416A PL378416A1 (pl) 2002-12-17 2003-12-01 Różnie podstawione pochodne guanidyny i ich zastosowanie jako leki o aktywności przeciwcukrzycowej i/lub przeciw otyłości

Country Status (12)

Country Link
US (1) US7368605B2 (https=)
EP (1) EP1575912A1 (https=)
JP (1) JP2006509816A (https=)
KR (1) KR20050089058A (https=)
CN (1) CN1729172A (https=)
AU (1) AU2003288534B2 (https=)
BR (1) BR0317397A (https=)
CA (1) CA2506685A1 (https=)
IT (1) ITRM20020625A1 (https=)
MX (1) MXPA05006326A (https=)
PL (1) PL378416A1 (https=)
WO (1) WO2004054967A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2873368B1 (fr) * 2004-07-26 2008-01-04 Merck Sante Soc Par Actions Si Derives de guanidine et leurs utilisations en therapeutique
CN101062906B (zh) * 2006-04-26 2012-02-08 中国人民解放军军事医学科学院毒物药物研究所 胍丁胺硫酸盐水合物及其用于戒毒,抗炎,降血糖以及胍丁胺代谢异常所致疾病的用途
CN101121677B (zh) * 2006-08-09 2011-05-11 中国人民解放军军事医学科学院毒物药物研究所 胍丁胺硫酸盐二水合物及其医药用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU190639B (en) * 1983-12-12 1986-09-29 Gyogyszerkutato Intezet Kv,Hu Process for production of new aminoguanidin derivatives
IT1219846B (it) * 1988-02-24 1990-05-24 Consiglio Nazionale Ricerche Nuovi derivati guandinici ad attivita' ipotensia,composizione che li contengono e relativo procedimento di estrazione e purificazione da materiale botanico
JPH06510760A (ja) * 1991-08-27 1994-12-01 ジ・アップジョン・カンパニー 代謝障害および代謝の治療法
GB9511757D0 (en) * 1995-05-19 1995-08-02 Univ Strathclyde Agents for reducing weight
KR19990076594A (ko) * 1995-12-22 1999-10-15 피터 존 기딩스 Niddm 치료용 아미노구아니딘

Also Published As

Publication number Publication date
CN1729172A (zh) 2006-02-01
WO2004054967A1 (en) 2004-07-01
AU2003288534B2 (en) 2009-07-02
US7368605B2 (en) 2008-05-06
JP2006509816A (ja) 2006-03-23
KR20050089058A (ko) 2005-09-07
ITRM20020625A1 (it) 2004-06-18
EP1575912A1 (en) 2005-09-21
US20060069100A1 (en) 2006-03-30
BR0317397A (pt) 2005-11-16
AU2003288534A1 (en) 2004-07-09
CA2506685A1 (en) 2004-07-01
MXPA05006326A (es) 2005-08-26

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)