PL377695A1 - Sinomenina i związki synomeniny, synteza i zastosowanie - Google Patents

Sinomenina i związki synomeniny, synteza i zastosowanie

Info

Publication number
PL377695A1
PL377695A1 PL377695A PL37769503A PL377695A1 PL 377695 A1 PL377695 A1 PL 377695A1 PL 377695 A PL377695 A PL 377695A PL 37769503 A PL37769503 A PL 37769503A PL 377695 A1 PL377695 A1 PL 377695A1
Authority
PL
Poland
Prior art keywords
sinomenine
synthesis
compounds
sinomenine compounds
Prior art date
Application number
PL377695A
Other languages
English (en)
Inventor
Guo-Wie Qin
Xi-Can Tang
Rui Wang
Tian-Xi Zhou
Pierre Lestage
Daniel-Henri Caignard
Pierre Renard
Original Assignee
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences
Les Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Les Laboratoires Servier filed Critical Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences
Publication of PL377695A1 publication Critical patent/PL377695A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL377695A 2002-11-28 2003-11-26 Sinomenina i związki synomeniny, synteza i zastosowanie PL377695A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB021538190A CN1328280C (zh) 2002-11-28 2002-11-28 汉防己碱和汉防己碱化合物,合成和应用

Publications (1)

Publication Number Publication Date
PL377695A1 true PL377695A1 (pl) 2006-02-06

Family

ID=32331921

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377695A PL377695A1 (pl) 2002-11-28 2003-11-26 Sinomenina i związki synomeniny, synteza i zastosowanie

Country Status (15)

Country Link
US (1) US20060009480A1 (pl)
EP (1) EP1565444A1 (pl)
JP (1) JP2006509755A (pl)
KR (1) KR100706462B1 (pl)
CN (2) CN1328280C (pl)
AU (1) AU2003290119A1 (pl)
BR (1) BR0316609A (pl)
CA (1) CA2507067A1 (pl)
EA (1) EA200500862A1 (pl)
MA (1) MA27573A1 (pl)
MX (1) MXPA05005687A (pl)
NO (1) NO20053139L (pl)
PL (1) PL377695A1 (pl)
WO (1) WO2004048340A1 (pl)
ZA (1) ZA200504055B (pl)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1298720C (zh) * 2005-03-18 2007-02-07 中国科学院上海有机化学研究所 C环连接有五元杂环的青藤碱衍生物和合成方法
CN1298718C (zh) * 2005-03-18 2007-02-07 中国科学院上海有机化学研究所 C环连接有吡嗪环的青藤碱衍生物、合成方法及其用途
CN100455571C (zh) * 2005-12-09 2009-01-28 湖南正清制药集团股份有限公司 青藤碱盐化合物及其制备方法
EP1959956A2 (en) * 2005-12-15 2008-08-27 Naturemed Group Corporation Sinomenine derivatives and preparation and uses thereof
CN101578101B (zh) * 2005-12-15 2012-05-23 自然医学公司 青藤碱衍生物的制备和应用
CN100408578C (zh) * 2006-03-15 2008-08-06 南京大学 一类17-酰基青藤碱衍生物及其制备方法
CN101092397B (zh) * 2006-06-19 2011-01-19 湖南正清制药集团股份有限公司 一种青藤碱结构改造化合物及其制备方法
CN1876634A (zh) * 2006-06-19 2006-12-13 湖南正清制药集团股份有限公司 一种青藤碱结构改造化合物及其制备方法
US20070290378A1 (en) * 2006-06-20 2007-12-20 International Business Machines Corporation Novel reworkable underfills for ceramic mcm c4 protection
CN100396686C (zh) * 2006-08-03 2008-06-25 西安皓天生物工程技术有限责任公司 一种汉防己甲素和汉防己乙素的制备方法
CN102093373A (zh) * 2007-06-19 2011-06-15 湖南正清制药集团股份有限公司 一种青藤碱结构改造化合物及其制备方法
NZ611651A (en) 2007-12-17 2014-11-28 Mallinckrodt Llc Sinomenine derivatives and processes for their synthesis
EP2398806A1 (en) * 2009-02-23 2011-12-28 Mallinckrodt LLC (+)-morphinanium n-oxides and processes for their production
EP2340832A1 (en) * 2009-12-23 2011-07-06 Universität Innsbruck Morphinan-6-one compounds for the treatment or prevention of neurodegenerative diseases
CN101798285B (zh) 2010-02-10 2012-05-23 中国科学院上海有机化学研究所 一种青藤碱衍生物、合成方法及其用途
CN101899004A (zh) * 2010-06-24 2010-12-01 江苏大学 青藤碱衍生物、制备方法及其医药用途
CN101948430A (zh) * 2010-09-01 2011-01-19 南京大学 青藤碱衍生物及其制备方法和应用
CN102532024B (zh) * 2011-12-28 2016-08-03 赵爱国 青藤碱衍生物
CN104306954B (zh) * 2014-09-25 2016-08-24 中山大学 Wry三肽在制备治疗阿尔茨海默症药物中的用途
CN104258371B (zh) * 2014-09-25 2016-06-15 中山大学 Www三肽在制备治疗阿尔茨海默症药物中的用途
CN104258372B (zh) * 2014-09-25 2017-01-25 中山大学 Rgd三肽在制备治疗阿尔茨海默症药物中的用途
CN104274817B (zh) * 2014-09-25 2016-06-15 中山大学 Wrw三肽在制备治疗阿尔茨海默症药物中的用途
EP3414437A4 (en) 2016-02-10 2020-04-29 Pilaar, James Gray IMPROVED INFLATABLE ACOUSTIC MITIGATION SYSTEM
CN107648179A (zh) * 2017-09-21 2018-02-02 浙江中医药大学 一种治疗类风湿性关节炎的新型皮肤给药制剂及其制备方法
CN108704640B (zh) * 2018-06-13 2021-03-30 绍兴市梓昂新材料有限公司 一种多孔氧化铂催化剂的制备方法
CN110433132B (zh) * 2019-08-19 2023-06-30 中国人民解放军军事科学院军事医学研究院 治疗创伤后应激障碍的粉防己碱鼻用制剂
CN113880764B (zh) * 2020-07-01 2023-04-18 北京师范大学 青藤碱衍生物及其制备方法与应用
CN114831990A (zh) * 2022-03-22 2022-08-02 台州恩泽医疗中心(集团) 青藤碱在制备治疗帕金森病药物组合物中的应用
CN115260098B (zh) * 2022-06-09 2024-06-04 澳门科技大学 Abcb5抑制剂在制备多耐药性类风湿性关节炎治疗药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912114A (en) * 1988-03-18 1990-03-27 Sandoz Ltd. Morphinan derivatives
KR100341950B1 (ko) * 1993-07-19 2002-11-29 도레이 가부시끼가이샤 뇌세포보호제
US6372756B1 (en) * 1998-02-20 2002-04-16 Avmax, Inc. Epimorphian compound and its use

Also Published As

Publication number Publication date
CN1504469A (zh) 2004-06-16
EA200500862A1 (ru) 2005-12-29
WO2004048340A1 (en) 2004-06-10
EP1565444A1 (en) 2005-08-24
NO20053139L (no) 2005-06-27
ZA200504055B (en) 2006-08-30
US20060009480A1 (en) 2006-01-12
BR0316609A (pt) 2005-10-11
CN1328280C (zh) 2007-07-25
JP2006509755A (ja) 2006-03-23
CA2507067A1 (en) 2004-06-10
KR20050071712A (ko) 2005-07-07
KR100706462B1 (ko) 2007-04-10
MXPA05005687A (es) 2005-08-16
MA27573A1 (fr) 2005-10-03
WO2004048340A8 (en) 2005-07-07
CN1720232A (zh) 2006-01-11
AU2003290119A1 (en) 2004-06-18

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)