PL376896A1 - Sposoby wytwarzania 5-androstenów podstawionych w pozycji C-7 - Google Patents

Sposoby wytwarzania 5-androstenów podstawionych w pozycji C-7

Info

Publication number
PL376896A1
PL376896A1 PL376896A PL37689603A PL376896A1 PL 376896 A1 PL376896 A1 PL 376896A1 PL 376896 A PL376896 A PL 376896A PL 37689603 A PL37689603 A PL 37689603A PL 376896 A1 PL376896 A1 PL 376896A1
Authority
PL
Poland
Prior art keywords
processes
androstenes
substituted
preparing
novel
Prior art date
Application number
PL376896A
Other languages
English (en)
Inventor
Peter G.M. Wuts
Original Assignee
Pharmacia & Upjohn Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Company Llc filed Critical Pharmacia & Upjohn Company Llc
Publication of PL376896A1 publication Critical patent/PL376896A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
PL376896A 2002-11-07 2003-03-21 Sposoby wytwarzania 5-androstenów podstawionych w pozycji C-7 PL376896A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42448802P 2002-11-07 2002-11-07

Publications (1)

Publication Number Publication Date
PL376896A1 true PL376896A1 (pl) 2006-01-09

Family

ID=32312815

Family Applications (1)

Application Number Title Priority Date Filing Date
PL376896A PL376896A1 (pl) 2002-11-07 2003-03-21 Sposoby wytwarzania 5-androstenów podstawionych w pozycji C-7

Country Status (19)

Country Link
US (1) US20040097475A1 (pl)
EP (1) EP1562974B1 (pl)
JP (1) JP2006508962A (pl)
KR (1) KR100667123B1 (pl)
CN (1) CN1694896A (pl)
AT (1) ATE354583T1 (pl)
AU (1) AU2003220139A1 (pl)
BR (1) BR0316052A (pl)
CA (1) CA2500580A1 (pl)
DE (1) DE60312029T2 (pl)
ES (1) ES2280739T3 (pl)
HK (1) HK1080088A1 (pl)
MX (1) MXPA05004024A (pl)
PL (1) PL376896A1 (pl)
RS (1) RS20050339A (pl)
RU (1) RU2289586C2 (pl)
TW (1) TWI280133B (pl)
WO (1) WO2004043986A1 (pl)
ZA (1) ZA200502698B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
CN1321128C (zh) * 2005-07-15 2007-06-13 浙江医药股份有限公司新昌制药厂 孕甾－4－烯－7，21－二甲酸，9，11－环氧－17－羟基－3－氧代，γ－内酯，甲酯，(7α,11α,17α)－的制备方法
CN101472579B (zh) * 2006-04-22 2013-07-03 霍利斯-伊登医药公司 药物和用途
CN103211821A (zh) * 2006-04-22 2013-07-24 霍利斯—伊登医药公司 药物和用途
US8354396B2 (en) * 2006-11-17 2013-01-15 Harbor Therapeutics, Inc. Drug identification and treatment method
US8217025B2 (en) * 2006-11-17 2012-07-10 Harbor Therapeutics, Inc. Drug screening and treatment methods
US20080153792A1 (en) * 2006-11-17 2008-06-26 Frincke James M Drug Identification and Treatment Method
US8486926B2 (en) * 2006-11-17 2013-07-16 Harbor Therapeutics, Inc. Steroid tetrol solid state forms
US20080221074A1 (en) * 2006-11-17 2008-09-11 Jaime Flores-Riveros Drug Screen and Treatment Method
DK2300489T3 (en) * 2008-06-06 2016-02-15 Neurmedix Inc PROCESSES FOR PREPARING 17-alkynyl-7-HYDROXY STEROIDS AND RELATED COMPOUNDS
US20100075937A1 (en) * 2008-09-24 2010-03-25 Hollis-Eden Pharmaceuticals, Inc. Patient populations and treatment methods
US20100227841A1 (en) * 2008-09-24 2010-09-09 Harbor BioSciencs, Inc. Patient populations and treatment methods
US20100222315A1 (en) * 2008-09-24 2010-09-02 Harbor BioSciencs, Inc. Patient populations and treatment methods
CN103087139B (zh) * 2011-11-08 2016-08-03 中国科学院上海药物研究所 一种坎利酮衍生物类甾体化合物、其制备方法及其在制备依普利酮中的用途
CN105753930A (zh) * 2016-03-30 2016-07-13 北京万全德众医药生物技术有限公司 依普利酮的一种合成方法
CN110698529A (zh) * 2019-11-19 2020-01-17 湖南新合新生物医药有限公司 一种依普利酮中间体△9,11烯酯的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069219A (en) * 1976-12-27 1978-01-17 G. D. Searle & Co. 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters
US4559332A (en) * 1983-04-13 1985-12-17 Ciba Geigy Corporation 20-Spiroxanes and analogues having an open ring E, processes for their manufacture, and pharmaceutical preparations thereof
US5227375A (en) * 1990-02-08 1993-07-13 Endorecherche, Inc. Aromatase inhibitors
US5237064A (en) * 1992-05-20 1993-08-17 Merck & Co., Inc. Process for producing 7β-substituted-aza-5αandrostan-3-ones
DE69637140T2 (de) * 1995-12-11 2008-04-10 G.D. Searle Llc, Chicago Verfahren zur herstellung einer epoxy-verbindung
US6887991B1 (en) * 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein
NZ336004A (en) * 1996-12-11 2001-04-27 G Process for preparation of 3-keto-7-alpha-alkoxycarbonyl substituted delta-4,5-steroid by reacting 4,5-dihydro-5,7-lactone steroid substrate in the presence of a base
US6716829B2 (en) * 2000-07-27 2004-04-06 Pharmacia Corporation Aldosterone antagonist and cyclooxygenase-2 inhibitor combination therapy to prevent or treat inflammation-related cardiovascular disorders

Also Published As

Publication number Publication date
WO2004043986A1 (en) 2004-05-27
ZA200502698B (en) 2006-07-26
KR100667123B1 (ko) 2007-01-12
CN1694896A (zh) 2005-11-09
HK1080088A1 (zh) 2006-04-21
KR20050084953A (ko) 2005-08-29
JP2006508962A (ja) 2006-03-16
RS20050339A (sr) 2007-08-03
BR0316052A (pt) 2005-09-20
US20040097475A1 (en) 2004-05-20
RU2005117372A (ru) 2006-01-20
DE60312029T2 (de) 2007-06-21
ATE354583T1 (de) 2007-03-15
AU2003220139A1 (en) 2004-06-03
ES2280739T3 (es) 2007-09-16
EP1562974A1 (en) 2005-08-17
EP1562974B1 (en) 2007-02-21
TW200407151A (en) 2004-05-16
RU2289586C2 (ru) 2006-12-20
DE60312029D1 (de) 2007-04-05
TWI280133B (en) 2007-05-01
CA2500580A1 (en) 2004-05-27
MXPA05004024A (es) 2005-06-08

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)