PL376751A1 - Bicykliczne podstawione aminy jako ligandy receptora histaminowego-3 - Google Patents
Bicykliczne podstawione aminy jako ligandy receptora histaminowego-3Info
- Publication number
- PL376751A1 PL376751A1 PL376751A PL37675103A PL376751A1 PL 376751 A1 PL376751 A1 PL 376751A1 PL 376751 A PL376751 A PL 376751A PL 37675103 A PL37675103 A PL 37675103A PL 376751 A1 PL376751 A1 PL 376751A1
- Authority
- PL
- Poland
- Prior art keywords
- histamine
- bicyclic
- receptor ligands
- substituted amines
- amines
- Prior art date
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- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
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| US10/292,422 US20040092521A1 (en) | 2002-11-12 | 2002-11-12 | Bicyclic-substituted amines as histamine-3 receptor ligands |
| US10/689,735 US7153889B2 (en) | 2002-11-12 | 2003-10-22 | Bicyclic-substituted amines as histamine-3 receptor ligands |
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| PL376751A PL376751A1 (pl) | 2002-11-12 | 2003-11-05 | Bicykliczne podstawione aminy jako ligandy receptora histaminowego-3 |
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| US7094790B2 (en) | 2003-05-07 | 2006-08-22 | Abbott Laboratories | Fused bicyclic-substituted amines as histamine-3 receptor ligands |
| US20040224952A1 (en) * | 2003-05-07 | 2004-11-11 | Cowart Marlon D. | Fused bicyclic-substituted amines as histamine-3 receptor ligands |
| CA2524787A1 (en) * | 2003-05-07 | 2004-11-25 | Abbott Laboratories | Fused bicyclic-substituted amines as histamine-3 receptor ligands |
| WO2005108370A1 (ja) * | 2004-04-16 | 2005-11-17 | Ajinomoto Co., Inc. | ベンゼン化合物 |
| US7205316B2 (en) | 2004-05-12 | 2007-04-17 | Abbott Laboratories | Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands |
| US7098222B2 (en) | 2004-05-12 | 2006-08-29 | Abbott Laboratories | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents |
| US20050256118A1 (en) * | 2004-05-12 | 2005-11-17 | Altenbach Robert J | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents |
| US20050256309A1 (en) * | 2004-05-12 | 2005-11-17 | Altenbach Robert J | Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands |
| DK1755593T3 (da) * | 2004-06-02 | 2008-05-19 | Hoffmann La Roche | Naphtalenderivater der er nyttige som histamin-3-receptorligander |
| MX2007004465A (es) * | 2004-10-19 | 2007-05-07 | Hoffmann La Roche | Derivados de quinolina. |
| EP1683523A1 (en) * | 2005-01-25 | 2006-07-26 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | 2-Phenylquinoxalines as inhibitors for MPP1 |
| US7553964B2 (en) | 2005-06-03 | 2009-06-30 | Abbott Laboratories | Cyclobutyl amine derivatives |
| CN101253159B (zh) * | 2005-09-01 | 2011-12-07 | 弗·哈夫曼-拉罗切有限公司 | 作为p2x3和p2x2/3调节剂的二氨基嘧啶类化合物 |
| US7576110B2 (en) | 2005-09-22 | 2009-08-18 | Abbott Laboratories | Benzothiazole cyclobutyl amine derivatives |
| MX2008016343A (es) | 2006-06-23 | 2009-01-19 | Abbott Lab | Derivados ciclopropil amina como moduladores del receptro de histamina h3. |
| US9108948B2 (en) | 2006-06-23 | 2015-08-18 | Abbvie Inc. | Cyclopropyl amine derivatives |
| US8153813B2 (en) | 2007-12-20 | 2012-04-10 | Abbott Laboratories | Benzothiazole and benzooxazole derivatives and methods of use |
| US8383657B2 (en) | 2007-12-21 | 2013-02-26 | Abbott Laboratories | Thiazolylidine urea and amide derivatives and methods of use thereof |
| US9186353B2 (en) | 2009-04-27 | 2015-11-17 | Abbvie Inc. | Treatment of osteoarthritis pain |
| GB201104267D0 (en) | 2011-03-14 | 2011-04-27 | Cancer Rec Tech Ltd | Pyrrolopyridineamino derivatives |
| WO2012162254A1 (en) * | 2011-05-23 | 2012-11-29 | Elan Pharmaceuticals, Inc. | Inhibitors of lrrk2 kinase activity |
| US9181275B2 (en) | 2011-08-11 | 2015-11-10 | Abbvie Inc. | Mercaptoamidine derivatives and methods of use |
| EP2825533B1 (en) | 2012-03-13 | 2016-10-19 | Basf Se | Fungicidal pyrimidine compounds |
| GB201216017D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Inhibitor compounds |
| GB201216018D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Pharmacologically active compounds |
| WO2014086701A1 (en) * | 2012-12-06 | 2014-06-12 | F. Hoffmann-La Roche Ag | Substituted thiazole compounds |
| ES2886914T3 (es) * | 2013-01-09 | 2021-12-21 | Arena Pharm Inc | Acido (R)-3-(4'-(2-(2-metilpirrolidin-1-il)etil)-bifenil-4-il)propanoico como moduladores del receptor de histamina H3 para el tratamiento de trastornos cognitivos |
| WO2015036059A1 (en) | 2013-09-16 | 2015-03-19 | Basf Se | Fungicidal pyrimidine compounds |
| US20160221964A1 (en) | 2013-09-16 | 2016-08-04 | Basf Se | Fungicidal pyrimidine compounds |
| GB201403536D0 (en) | 2014-02-28 | 2014-04-16 | Cancer Rec Tech Ltd | Inhibitor compounds |
| WO2017133752A1 (en) * | 2016-02-04 | 2017-08-10 | Merck Patent Gmbh | [1,5]naphthyridine compounds and polymers as semiconductors |
| KR20200033249A (ko) | 2017-06-05 | 2020-03-27 | 피티씨 테라퓨틱스, 인크. | 헌팅턴병 치료 화합물 |
| GB201709840D0 (en) | 2017-06-20 | 2017-08-02 | Inst Of Cancer Research: Royal Cancer Hospital | Methods and medical uses |
| US12103926B2 (en) | 2018-03-27 | 2024-10-01 | Ptc Therapeutics, Inc. | Compounds for treating huntington's disease |
| EA202092899A1 (ru) | 2018-06-27 | 2021-05-14 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Гетероарильные соединения для лечения болезни гентингтона |
| CN110669504B (zh) * | 2019-11-15 | 2022-01-04 | 北京建筑大学 | 一种检测饮用水中醛类特征嗅味物质的荧光探针 |
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| DE556324C (de) * | 1929-04-05 | 1932-08-10 | Chemische Ind Ges | Verfahren zur Darstellung halogenhaltiger basischer AEther |
| CH149007A (de) * | 1929-04-05 | 1931-08-15 | Chem Ind Basel | Verfahren zur Darstellung eines halogenhaltigen basischen Äthers. |
| US1860286A (en) * | 1929-05-16 | 1932-05-24 | Soc Of Chemical Ind | Basic ethers of aryl-quinolines |
| US1949046A (en) * | 1930-03-24 | 1934-02-27 | Soc Of Chemical Ind | Basic ether containing halogen |
| US3139430A (en) * | 1960-12-20 | 1964-06-30 | Merck & Co Inc | 2-dialkylaminoalkoxy-6-substituted naphthalenes useful as new anticholesteremic agents |
| DE1543360C2 (de) * | 1966-07-27 | 1975-05-28 | Boehringer Mannheim Gmbh, 6800 Mannheim | N,N-disubstituierte2-(Aminoalkoxy)naphthaline und Verfahren zu deren Herstellung |
| NL131915C (pl) * | 1966-07-27 | |||
| GB1166538A (en) * | 1967-06-10 | 1969-10-08 | Pfizer Ltd | Substituted Tetrahydroquinolines |
| US3489756A (en) * | 1967-07-10 | 1970-01-13 | Merck & Co Inc | 2-carbocyclic-6-tertiary amino alkoxy naphthalenes and tetralins |
| JPS5649357A (en) * | 1979-09-28 | 1981-05-02 | Otsuka Pharmaceut Co Ltd | Quinoline derivative |
| JP2551298B2 (ja) * | 1991-04-25 | 1996-11-06 | 田辺製薬株式会社 | 抗うつ剤 |
| US5480883A (en) * | 1991-05-10 | 1996-01-02 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| EP1019375A1 (en) * | 1997-03-25 | 2000-07-19 | Astra Pharmaceuticals Limited | Novel pyridine derivatives and pharmaceutical compositions containing them |
| EP0971892A1 (en) * | 1997-03-25 | 2000-01-19 | Astra Pharmaceuticals Limited | Novel pyridine derivatives and pharmaceutical compositions containing them |
| JP4370002B2 (ja) * | 1997-08-08 | 2009-11-25 | 富山化学工業株式会社 | キノロンカルボン酸誘導体またはその塩 |
| EP0982300A3 (en) * | 1998-07-29 | 2000-03-08 | Societe Civile Bioprojet | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
| JP2002275157A (ja) * | 1998-11-20 | 2002-09-25 | Torii Yakuhin Kk | 新規ナフタレン誘導体 |
| AU4058399A (en) * | 1998-11-20 | 2000-06-13 | Torii Pharmaceutical Co., Ltd. | Naphthalene derivatives |
| WO2002018335A1 (en) * | 2000-08-28 | 2002-03-07 | Yamanouchi Pharmaceutical Co., Ltd. | Cyclic amine derivatives |
| US7115630B2 (en) * | 2000-10-02 | 2006-10-03 | Janssen Pharmaceutica N.V. | Metabotropic glutamate receptor antagonists |
| BR0205829A (pt) * | 2001-03-16 | 2005-03-08 | Abbott Lab | Novas aminas como ligantes dos receptores de histamina-3 e suas aplicações terapêuticas |
-
2003
- 2003-11-05 JP JP2004551799A patent/JP4820094B2/ja not_active Expired - Fee Related
- 2003-11-05 CA CA2505427A patent/CA2505427C/en not_active Expired - Fee Related
- 2003-11-05 AU AU2003291329A patent/AU2003291329A1/en not_active Abandoned
- 2003-11-05 CA CA2765093A patent/CA2765093A1/en not_active Abandoned
- 2003-11-05 PL PL376751A patent/PL376751A1/pl not_active Application Discontinuation
- 2003-11-05 EP EP03768721A patent/EP1569637A1/en not_active Withdrawn
- 2003-11-05 MX MXPA05005116A patent/MXPA05005116A/es active IP Right Grant
- 2003-11-05 WO PCT/US2003/035365 patent/WO2004043458A1/en not_active Ceased
- 2003-11-12 TW TW092131661A patent/TWI359658B/zh not_active IP Right Cessation
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2010
- 2010-10-20 JP JP2010235798A patent/JP2011063594A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011063594A (ja) | 2011-03-31 |
| CA2765093A1 (en) | 2004-05-27 |
| EP1569637A1 (en) | 2005-09-07 |
| CA2505427A1 (en) | 2004-05-27 |
| MXPA05005116A (es) | 2005-07-01 |
| TW200418454A (en) | 2004-10-01 |
| JP4820094B2 (ja) | 2011-11-24 |
| CA2505427C (en) | 2012-04-03 |
| TWI359658B (en) | 2012-03-11 |
| JP2006514926A (ja) | 2006-05-18 |
| WO2004043458A1 (en) | 2004-05-27 |
| AU2003291329A1 (en) | 2004-06-03 |
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