PL366122A1 - Zastosowanie hemolizyny CLyA do wydzielania białek - Google Patents
Zastosowanie hemolizyny CLyA do wydzielania białekInfo
- Publication number
- PL366122A1 PL366122A1 PL01366122A PL36612201A PL366122A1 PL 366122 A1 PL366122 A1 PL 366122A1 PL 01366122 A PL01366122 A PL 01366122A PL 36612201 A PL36612201 A PL 36612201A PL 366122 A1 PL366122 A1 PL 366122A1
- Authority
- PL
- Poland
- Prior art keywords
- clya
- hemolysin
- excretion
- proteins
- protein
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 108010006464 Hemolysin Proteins Proteins 0.000 title 1
- 230000029142 excretion Effects 0.000 title 1
- 239000003228 hemolysin Substances 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25251600P | 2000-11-22 | 2000-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL366122A1 true PL366122A1 (pl) | 2005-01-24 |
Family
ID=22956340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL01366122A PL366122A1 (pl) | 2000-11-22 | 2001-11-23 | Zastosowanie hemolizyny CLyA do wydzielania białek |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7056700B2 (pl) |
| EP (1) | EP1412502B1 (pl) |
| JP (1) | JP3976685B2 (pl) |
| AT (1) | ATE474926T1 (pl) |
| AU (1) | AU2001297770B2 (pl) |
| CA (1) | CA2430322A1 (pl) |
| CZ (1) | CZ20031378A3 (pl) |
| DE (1) | DE60142646D1 (pl) |
| ES (1) | ES2349114T3 (pl) |
| HU (1) | HUP0303843A3 (pl) |
| MX (1) | MXPA03004562A (pl) |
| NO (1) | NO20032286L (pl) |
| NZ (1) | NZ525735A (pl) |
| PL (1) | PL366122A1 (pl) |
| WO (1) | WO2002083890A2 (pl) |
| ZA (1) | ZA200303851B (pl) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10208653A1 (de) * | 2002-02-28 | 2003-09-18 | Medinnova Ges Med Innovationen | Mikroorganismus als Träger von Nukleotidsequenzen kodierend für Zellantigene zur Behandlung von Tumoren |
| US20080124355A1 (en) * | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
| CN105950608B (zh) * | 2007-05-22 | 2019-12-17 | 康乃尔研究基金会有限公司 | 蛋白质在细菌及其衍生小泡表面展示的组合物和方法及其用途 |
| CN101827943B (zh) * | 2007-05-22 | 2016-04-13 | 康乃尔研究基金会有限公司 | 蛋白质在细菌及其衍生小泡表面展示的组合物和方法及其用途 |
| ES2473605T3 (es) | 2008-06-03 | 2014-07-07 | University Of Maryland, Baltimore | ClyA no hemol�tica para la excreci�n de proteínas |
| US20120020996A1 (en) * | 2008-08-06 | 2012-01-26 | Jonathan Lewis Telfer | Vaccines against clostridium difficile and methods of use |
| US8211656B2 (en) | 2008-08-13 | 2012-07-03 | The Invention Science Fund I, Llc | Biological targeting compositions and methods of using the same |
| US20100042072A1 (en) * | 2008-08-13 | 2010-02-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Biological targeting compositions and methods of using the same |
| US20110092961A1 (en) * | 2008-08-13 | 2011-04-21 | Searete Llc | Artificial cells |
| US20100040546A1 (en) * | 2008-08-13 | 2010-02-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Biological targeting compositions and methods of using the same |
| US8647642B2 (en) * | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| US10046040B2 (en) | 2009-11-16 | 2018-08-14 | University Of Maryland, Baltimore | Multivalent live vector vaccine against Clostridium difficile-associated disease |
| US8771669B1 (en) | 2010-02-09 | 2014-07-08 | David Gordon Bermudes | Immunization and/or treatment of parasites and infectious agents by live bacteria |
| CN113046285A (zh) | 2012-04-06 | 2021-06-29 | 康奈尔大学 | 用于稳健的体液及细胞免疫应答的亚单位疫苗递送平台 |
| WO2015144936A1 (en) * | 2014-03-28 | 2015-10-01 | Novozymes A/S | Resolubilization of protein crystals at low ph |
| AR102547A1 (es) | 2014-11-07 | 2017-03-08 | Takeda Vaccines Inc | Vacunas contra la enfermedad de manos, pies y boca y métodos de fabricación y su uso |
| AU2015252119A1 (en) | 2014-11-07 | 2016-05-26 | Takeda Vaccines, Inc. | Hand, foot, and mouth vaccines and methods of manufacture and use thereof |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| BR112020008652A2 (pt) | 2017-11-03 | 2020-11-10 | Takeda Vaccines, Inc. | vacinas e composições imunogênicas contra zika e métodos de uso das mesmas |
| CN110747155A (zh) * | 2019-11-12 | 2020-02-04 | 湖南大学 | 减毒重组工程菌及其制备方法、应用和肿瘤靶向药物 |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
| US4372945A (en) | 1979-11-13 | 1983-02-08 | Likhite Vilas V | Antigen compounds |
| US4355117A (en) | 1980-10-08 | 1982-10-19 | Nabisco Brands, Inc. | Process for preparing agglomerated fibrous cellulose |
| IL61904A (en) | 1981-01-13 | 1985-07-31 | Yeda Res & Dev | Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same |
| US4665027A (en) | 1983-11-03 | 1987-05-12 | Bio-Process Innovation, Inc. | Immobilized cell reactor-separator with simultaneous product separation and methods for design and use thereof |
| US5387744A (en) | 1987-06-04 | 1995-02-07 | Washington University | Avirulent microbes and uses therefor: Salmonella typhi |
| KR890005273A (ko) | 1987-09-09 | 1989-05-13 | 이정오 | 2중 실관 반응기에 의한 구연산의 연속 생산방법 |
| DE4239612A1 (de) | 1992-11-25 | 1994-05-26 | Cultor Oy | Bioreaktor mit immobilisierten, Milchsäure-produzierenden Bakterien und dessen Verwendung in Fermentationsverfahren |
| US5525504A (en) | 1993-04-30 | 1996-06-11 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Cytolysin gene and gene product |
| WO1994028137A1 (en) * | 1993-05-24 | 1994-12-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Regulator of contact-mediated hemolysin |
| US5512480A (en) | 1994-03-11 | 1996-04-30 | Baxter International Inc. | Flow-through bioreactor with grooves for cell retention |
| US5585266A (en) | 1995-10-05 | 1996-12-17 | Plitt; Cheryl A. | Immobilized cell bioreactor |
| US6413768B1 (en) | 1998-12-02 | 2002-07-02 | University Of Maryland | Expression plasmids |
| US6436703B1 (en) | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
-
2001
- 2001-11-23 NZ NZ525735A patent/NZ525735A/en unknown
- 2001-11-23 PL PL01366122A patent/PL366122A1/pl not_active Application Discontinuation
- 2001-11-23 HU HU0303843A patent/HUP0303843A3/hu unknown
- 2001-11-23 WO PCT/US2001/044185 patent/WO2002083890A2/en active IP Right Grant
- 2001-11-23 ES ES01273749T patent/ES2349114T3/es not_active Expired - Lifetime
- 2001-11-23 JP JP2002588737A patent/JP3976685B2/ja not_active Expired - Fee Related
- 2001-11-23 CA CA002430322A patent/CA2430322A1/en not_active Abandoned
- 2001-11-23 AT AT01273749T patent/ATE474926T1/de not_active IP Right Cessation
- 2001-11-23 CZ CZ20031378A patent/CZ20031378A3/cs unknown
- 2001-11-23 US US09/993,292 patent/US7056700B2/en not_active Expired - Lifetime
- 2001-11-23 DE DE60142646T patent/DE60142646D1/de not_active Expired - Lifetime
- 2001-11-23 AU AU2001297770A patent/AU2001297770B2/en not_active Ceased
- 2001-11-23 EP EP01273749A patent/EP1412502B1/en not_active Expired - Lifetime
- 2001-11-23 MX MXPA03004562A patent/MXPA03004562A/es not_active Application Discontinuation
-
2003
- 2003-05-19 ZA ZA200303851A patent/ZA200303851B/xx unknown
- 2003-05-21 NO NO20032286A patent/NO20032286L/no not_active Application Discontinuation
-
2005
- 2005-12-12 US US11/298,526 patent/US7459161B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7459161B2 (en) | 2008-12-02 |
| US20060147461A1 (en) | 2006-07-06 |
| ZA200303851B (en) | 2004-05-11 |
| US7056700B2 (en) | 2006-06-06 |
| WO2002083890A3 (en) | 2004-02-26 |
| ATE474926T1 (de) | 2010-08-15 |
| MXPA03004562A (es) | 2003-09-10 |
| WO2002083890A2 (en) | 2002-10-24 |
| EP1412502A2 (en) | 2004-04-28 |
| HUP0303843A2 (hu) | 2004-03-01 |
| ES2349114T3 (es) | 2010-12-28 |
| NO20032286L (no) | 2003-07-07 |
| NO20032286D0 (no) | 2003-05-21 |
| DE60142646D1 (en) | 2010-09-02 |
| HUP0303843A3 (en) | 2010-01-28 |
| AU2001297770B2 (en) | 2007-04-05 |
| CZ20031378A3 (cs) | 2003-09-17 |
| NZ525735A (en) | 2005-07-29 |
| JP3976685B2 (ja) | 2007-09-19 |
| JP2004532634A (ja) | 2004-10-28 |
| CA2430322A1 (en) | 2002-10-24 |
| EP1412502B1 (en) | 2010-07-21 |
| US20020146430A1 (en) | 2002-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |