PL366100A1 - Sposób zmniejszania toksyczności chemioterapii złożonej - Google Patents

Sposób zmniejszania toksyczności chemioterapii złożonej

Info

Publication number
PL366100A1
PL366100A1 PL01366100A PL36610001A PL366100A1 PL 366100 A1 PL366100 A1 PL 366100A1 PL 01366100 A PL01366100 A PL 01366100A PL 36610001 A PL36610001 A PL 36610001A PL 366100 A1 PL366100 A1 PL 366100A1
Authority
PL
Poland
Prior art keywords
reducing toxicity
combined chemotherapies
chemotherapies
combined
toxicity
Prior art date
Application number
PL01366100A
Other languages
English (en)
Inventor
Luca Gianni
Giorgio Minotti
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of PL366100A1 publication Critical patent/PL366100A1/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL01366100A 2000-09-22 2001-09-06 Sposób zmniejszania toksyczności chemioterapii złożonej PL366100A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23449600P 2000-09-22 2000-09-22
PCT/US2001/027620 WO2002024179A2 (en) 2000-09-22 2001-09-06 Method for reducing toxicity of combined chemotherapies

Publications (1)

Publication Number Publication Date
PL366100A1 true PL366100A1 (pl) 2005-01-24

Family

ID=22881621

Family Applications (1)

Application Number Title Priority Date Filing Date
PL01366100A PL366100A1 (pl) 2000-09-22 2001-09-06 Sposób zmniejszania toksyczności chemioterapii złożonej

Country Status (11)

Country Link
US (2) US6906040B2 (pl)
EP (1) EP1318794A2 (pl)
JP (1) JP2004525860A (pl)
AU (1) AU2001288805A1 (pl)
CA (1) CA2422964A1 (pl)
CZ (1) CZ2003837A3 (pl)
HU (1) HUP0302599A3 (pl)
MX (1) MXPA03002494A (pl)
NO (1) NO20031309L (pl)
PL (1) PL366100A1 (pl)
WO (1) WO2002024179A2 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7314862B2 (en) * 2003-09-25 2008-01-01 Astellas Pharma Inc. Antitumor agent
US8735394B2 (en) 2005-02-18 2014-05-27 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
MX383644B (es) 2005-02-18 2025-03-14 Abraxis Bioscience Llc Combinaciones y metodos de administracion de agentes terapeuticos y terapia de combinacion.
KR101894689B1 (ko) 2010-03-29 2018-09-04 아브락시스 바이오사이언스, 엘엘씨 암의 치료 방법
KR20180050426A (ko) 2010-03-29 2018-05-14 아브락시스 바이오사이언스, 엘엘씨 치료제의 약물 전달 및 유효성 향상 방법
CA2801645A1 (en) 2010-06-04 2011-12-08 Abraxis Bioscience, Llc Use of nanoparticules comprising a taxane and an albumin in the treatment of pancreatic cancer

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695918A1 (de) 1968-01-03 1971-05-06 Thomae Gmbh Dr K Verfahren zur Herstellung von alpha-Aminoketonen
ES444470A1 (es) 1976-01-20 1977-05-16 Gema S A Y Antibioticos S A Proceso de acilacion de acidos aminopenicilanicos, aminoce- falosporanicos, aminodesacetoxicefalosporanicos y sus deri- vados.
US4203900A (en) 1977-01-03 1980-05-20 The Dow Chemical Company Process for preparing 2-oxazolines
US4543414A (en) 1978-12-05 1985-09-24 The Dow Chemical Company Liquid phase preparation of 2-substituted-2-oxazolines with cadmium salt catalysts
US4443611A (en) 1978-12-05 1984-04-17 The Dow Chemical Company Liquid phase preparation of 2-H-2-oxazolines and 2-substituted-2-oxazolines
US4206221A (en) 1979-01-03 1980-06-03 The United States Of America As Represented By The Secretary Of Agriculture Cephalomannine and its use in treating leukemic tumors
JPS55145650A (en) 1979-04-28 1980-11-13 Nippon Kayaku Co Ltd Intermediate and its preparation
DE2919891A1 (de) 1979-05-17 1980-12-04 Bayer Ag Substituierte 4-amino-2-aza-1,3- butadiene, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von heterocyclischen verbindungen
US4360678A (en) 1979-10-01 1982-11-23 Monsanto Company 2-Substituted-4-alkyl or trihaloalkyl-5-diazolecarboxylic acids
US4303439A (en) 1979-10-01 1981-12-01 Monsanto Company 2-Substituted-4-alkyl or trihaloalkyl-5-oxazolecarboxylic acids as safening agents
US4354029A (en) 1981-11-30 1982-10-12 The Dow Chemical Company Preparation of 2-substituted-2-oxazolines with organic zinc salt catalysts
IT1173213B (it) 1984-02-03 1987-06-18 Zambon Spa Procedimento per fluorurare alcuni derivati dall'1l-fenil-2-ammino-1,3-propandiolo e loro intermedi
JPS60222416A (ja) 1984-04-17 1985-11-07 Sogo Yatsukou Kk 皮膚用剤
JPS615022A (ja) 1984-06-19 1986-01-10 Advance Res & Dev Co Ltd 腸内細菌叢改善剤
JPS6151578A (ja) 1984-08-21 1986-03-14 Nec Corp 電子回路装置障害診断方式
JPS61115022A (ja) 1984-11-12 1986-06-02 Sogo Yatsukou Kk 血清脂質低下剤
ZA872997B (en) 1986-05-09 1988-12-28 Warner Lambert Co Novel styryl pyrazoles,isoxazoles and analogs thereof having activity as 5-lipoxygenase inhibitors,pharmaceutical compositions and methods of use therefor
FR2601676B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2601675B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
JP2503994B2 (ja) 1986-09-02 1996-06-05 味の素株式会社 オキサゾリンカルボン酸誘導体及びその製造法
US4877881A (en) 1987-04-06 1989-10-31 Warner-Lambert Company Process of preparing pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxygenase inhibitors
US4876399A (en) 1987-11-02 1989-10-24 Research Corporation Technologies, Inc. Taxols, their preparation and intermediates thereof
US4942184A (en) 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
FR2629818B1 (fr) 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2629819B1 (fr) 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
EP0359516B1 (en) 1988-09-14 1994-08-10 Schering Corporation Process for preparing oxazoline compounds
US4960790A (en) 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
US5175315A (en) 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5015744A (en) 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
US5136060A (en) 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5059699A (en) 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5278324A (en) 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
TW223634B (pl) 1991-03-18 1994-05-11 Kingston David G I
US5194635A (en) 1991-03-18 1993-03-16 Virginia Tech Intellectual Properties, Inc. Rearranged taxol compounds and method of using in testing of in vivo activity
AU2005692A (en) 1991-05-08 1992-12-21 United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Method for designing cancer treatment regimens and methods and pharmaceutical compositions for the treatment of cancer
US5227400A (en) 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5721268A (en) 1991-09-23 1998-02-24 Florida State University C7 taxane derivatives and pharmaceutical compositions containing them
US5728725A (en) 1991-09-23 1998-03-17 Florida State University C2 taxane derivaties and pharmaceutical compositions containing them
US5399726A (en) 1993-01-29 1995-03-21 Florida State University Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
US5710287A (en) 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US5283253A (en) 1991-09-23 1994-02-01 Florida State University Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US5243045A (en) 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5272171A (en) 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
IT1254517B (it) 1992-03-06 1995-09-25 Indena Spa 14-beta idrossi-10-deacetil-baccatina iii, suoi derivati, loro prepazione ed impiego terapeutico
US5208237A (en) 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5440056A (en) 1992-04-17 1995-08-08 Abbott Laboratories 9-deoxotaxane compounds
DE69325454T2 (de) 1992-04-17 2000-01-20 Abbott Laboratories, Abbott Park Taxol-derivate
US5254580A (en) 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
US5319112A (en) 1992-08-18 1994-06-07 Virgnia Tech Intellectual Properties, Inc. Method for the conversion of cephalomannine to taxol and for the preparation of N-acyl analogs of taxol
FR2696460B1 (fr) 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2696458B1 (fr) 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2696464B1 (fr) 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
US5420337A (en) 1992-11-12 1995-05-30 E. R. Squibb & Sons, Inc. Enzymatic reduction method for the preparation of compounds useful for preparing taxanes
FR2698871B1 (fr) 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
MX9307777A (es) 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
AU679206B2 (en) * 1992-12-23 1997-06-26 Bristol-Myers Squibb Company Novel sidechain-bearing taxanes and intermediates thereof
US5973160A (en) 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
US5646176A (en) 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
CA2111527C (en) * 1992-12-24 2000-07-18 Jerzy Golik Phosphonooxymethyl ethers of taxane derivatives
BR9405687C1 (pt) 1993-02-05 2001-08-07 Bryn Mawr College Processo quìmico utilizável na produção de análogos de taxol e, composto quìmico
PT982301E (pt) 1993-06-11 2004-02-27 Upjohn Co Utilizacao antineoplasica de delta-6,7-taxois e composicoes farmaceuticas que oscontem
FR2706457B1 (fr) 1993-06-16 1995-07-28 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs.
US5468769A (en) 1993-07-15 1995-11-21 Abbott Laboratories Paclitaxel derivatives
US6005120A (en) 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
US5405972A (en) 1993-07-20 1995-04-11 Florida State University Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
FR2718137B1 (fr) 1994-04-05 1996-04-26 Rhone Poulenc Rorer Sa Procédé de préparation de trialcoylsilyl-7 baccatine III.
US5449790A (en) 1994-04-06 1995-09-12 Hauser Chemical Research, Inc. Preparation of 10-deacetylbaccatin III and 7-protected-10-deacetylbaccatin III derivatives from 10-deacetyl taxol A, 10-deacetyl taxol B, and 10-deacetyl taxol C
CA2192373A1 (en) 1994-06-09 1995-12-14 Hirofumi Terasawa Deacetoxytaxol derivative
US5677470A (en) 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
WO1996000724A1 (en) 1994-06-28 1996-01-11 Pharmacia & Upjohn Company 7-ether-taxol analogs, antineoplastic use and pharmaceutical compositions containing them
FR2726272B1 (fr) 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
AU4133096A (en) 1994-10-28 1996-05-23 Research Foundation Of The State University Of New York, The Taxoid derivatives, their preparation and their use as antitumor agents
US6100411A (en) 1994-10-28 2000-08-08 The Research Foundation Of State University Of New York Taxoid anti-tumor agents and pharmaceutical compositions thereof
WO1996014309A1 (en) 1994-11-04 1996-05-17 Pharmacia & Upjohn S.P.A Taxane derivatives
CA2162759A1 (en) 1994-11-17 1996-05-18 Kenji Tsujihara Baccatin derivatives and processes for preparing the same
AU4548296A (en) 1995-02-02 1996-08-21 Daiichi Pharmaceutical Co., Ltd. Ether derivative
MA23823A1 (fr) * 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
US5847170A (en) 1995-03-27 1998-12-08 Rhone-Poulenc Rorer, S.A. Taxoids, their preparation and pharmaceutical compositions containing them
CA2231837A1 (en) 1995-09-13 1997-03-20 Florida State University Radiosensitizing taxanes and their pharmaceutical preparations
FR2742753B1 (fr) 1995-12-22 1998-01-30 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
JPH09208572A (ja) 1996-01-29 1997-08-12 Dai Ichi Seiyaku Co Ltd 18位置換タキソール誘導体
FR2745814B1 (fr) 1996-03-06 1998-04-03 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US5773461A (en) 1996-06-06 1998-06-30 Bristol-Myers Squibb Company 7-deoxy-6-substituted paclitaxels
US5635531A (en) 1996-07-08 1997-06-03 Bristol-Myers Squibb Company 3'-aminocarbonyloxy paclitaxels
FR2750989B1 (fr) 1996-07-09 1998-09-25 Rhone Poulenc Rorer Sa Procede de monoacylation d'hydroxy taxanes
WO1998022451A1 (en) 1996-11-19 1998-05-28 Daiichi Pharmaceutical Co., Ltd. Taxol derivatives
WO1999033462A1 (en) 1997-12-31 1999-07-08 Virginia Tech Intellectual Properties, Inc. 2-aroyl-4-acyl paclitaxel (taxol) analogs
US6020507A (en) 1998-03-02 2000-02-01 Bristol-Myers Squibb Company Synthesis of paclitaxel from baccatin III by protection of the 7-hydroxyl of baccatin III using a strong base and an electrophile
HUP0202448A3 (en) * 1999-08-11 2005-02-28 Bristol Myers Squibb Co Process for preparation of paclitaxel c-4 methyl carbonate analog
AU765588C (en) * 1999-11-24 2004-12-16 Immunogen, Inc. Cytotoxic agents comprising taxanes and their therapeutic use

Also Published As

Publication number Publication date
WO2002024179A2 (en) 2002-03-28
US20040077561A1 (en) 2004-04-22
AU2001288805A1 (en) 2002-04-02
EP1318794A2 (en) 2003-06-18
CA2422964A1 (en) 2002-03-28
US6906040B2 (en) 2005-06-14
JP2004525860A (ja) 2004-08-26
US20020049170A1 (en) 2002-04-25
CZ2003837A3 (cs) 2004-12-15
US6927211B2 (en) 2005-08-09
NO20031309D0 (no) 2003-03-21
WO2002024179A3 (en) 2003-03-13
HUP0302599A2 (hu) 2003-11-28
NO20031309L (no) 2003-05-08
HUP0302599A3 (en) 2005-05-30
MXPA03002494A (es) 2004-05-24

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