PL3652148T3 - Amorficzna postać trifenylooctanu wilanterolu i sposby jej wytwarzania - Google Patents
Amorficzna postać trifenylooctanu wilanterolu i sposby jej wytwarzaniaInfo
- Publication number
- PL3652148T3 PL3652148T3 PL18752193T PL18752193T PL3652148T3 PL 3652148 T3 PL3652148 T3 PL 3652148T3 PL 18752193 T PL18752193 T PL 18752193T PL 18752193 T PL18752193 T PL 18752193T PL 3652148 T3 PL3652148 T3 PL 3652148T3
- Authority
- PL
- Poland
- Prior art keywords
- wilanterol
- production
- methods
- amorphous form
- triphenyl acetate
- Prior art date
Links
- YJTKZCDBKVTVBY-UHFFFAOYSA-N 1,3-Diphenylbenzene Chemical compound C1=CC=CC=C1C1=CC=CC(C=2C=CC=CC=2)=C1 YJTKZCDBKVTVBY-UHFFFAOYSA-N 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
- C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
- C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT110209A PT110209B (pt) | 2017-07-19 | 2017-07-19 | Formas polimórficas de trifenatato de vilanterol e processos para a preparação das mesmas. |
| PT2017110209 | 2017-07-19 | ||
| PCT/GB2018/051940 WO2019016512A1 (en) | 2017-07-19 | 2018-07-09 | POLYMORPHIC FORM OF VILANTEROL TRIFENATATE AND METHODS OF PREPARATION THEREOF |
| EP18752193.5A EP3652148B1 (en) | 2017-07-19 | 2018-07-09 | Amorphous form of vilanterol trifenatate and processes for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3652148T3 true PL3652148T3 (pl) | 2021-12-20 |
Family
ID=63143265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18752193T PL3652148T3 (pl) | 2017-07-19 | 2018-07-09 | Amorficzna postać trifenylooctanu wilanterolu i sposby jej wytwarzania |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11434194B2 (pl) |
| EP (2) | EP3652148B1 (pl) |
| JP (2) | JP2020528057A (pl) |
| KR (2) | KR102572035B1 (pl) |
| CN (3) | CN111108091B (pl) |
| AU (2) | AU2018303782B9 (pl) |
| BR (1) | BR112020001171A2 (pl) |
| CA (2) | CA3070043A1 (pl) |
| DK (1) | DK3652148T3 (pl) |
| ES (1) | ES2899367T3 (pl) |
| HU (1) | HUE056419T2 (pl) |
| IL (3) | IL298421A (pl) |
| MX (2) | MX392899B (pl) |
| PL (1) | PL3652148T3 (pl) |
| PT (1) | PT110209B (pl) |
| WO (2) | WO2019016511A2 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT110209B (pt) | 2017-07-19 | 2021-05-17 | Hovione Farm Sa | Formas polimórficas de trifenatato de vilanterol e processos para a preparação das mesmas. |
| EP4013398B1 (en) * | 2019-08-16 | 2025-12-31 | Melody Healthcare Pvt. Ltd. | IMPROVED PROCESS FOR THE PREPARATION OF VILANTEROL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF |
| EP4188905B1 (en) * | 2020-07-27 | 2024-09-11 | Inke, S.A. | Method for the purification of vilanterol trifenatate |
| CN114441677B (zh) * | 2022-01-25 | 2024-06-11 | 上海方予健康医药科技有限公司 | 一种同时检测三苯乙酸维兰特罗多种基因杂质的方法 |
| CN116199590B (zh) * | 2022-12-26 | 2024-12-24 | 湖北美林药业有限公司 | 一种盐酸多巴酚丁胺及其注射剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2438985T3 (es) * | 2001-09-14 | 2014-01-21 | Glaxo Group Limited | Formulación de inhalación que comprende derivados de fenetanolamina para el tratamiento de enfermedades respiratorias |
| US20150239862A1 (en) * | 2012-09-13 | 2015-08-27 | Perrigo Api Ltd. | Process for the preparation of vilanterol and intermediates thereof |
| JP6758196B2 (ja) | 2014-05-28 | 2020-09-23 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | Ｃｏｐｄの治療におけるフルチカゾンフランカルボン酸エステル |
| WO2017001907A1 (en) | 2015-06-29 | 2017-01-05 | Teva Pharmaceuticals International Gmbh | Biocatalytic processes for the preparation of vilanterol |
| PT110209B (pt) | 2017-07-19 | 2021-05-17 | Hovione Farm Sa | Formas polimórficas de trifenatato de vilanterol e processos para a preparação das mesmas. |
-
2017
- 2017-07-19 PT PT110209A patent/PT110209B/pt active IP Right Grant
-
2018
- 2018-07-09 KR KR1020207004628A patent/KR102572035B1/ko active Active
- 2018-07-09 HU HUE18752193A patent/HUE056419T2/hu unknown
- 2018-07-09 MX MX2020000548A patent/MX392899B/es unknown
- 2018-07-09 US US16/631,683 patent/US11434194B2/en active Active
- 2018-07-09 IL IL298421A patent/IL298421A/en unknown
- 2018-07-09 CN CN201880060726.0A patent/CN111108091B/zh not_active Expired - Fee Related
- 2018-07-09 ES ES18752193T patent/ES2899367T3/es active Active
- 2018-07-09 AU AU2018303782A patent/AU2018303782B9/en not_active Ceased
- 2018-07-09 EP EP18752193.5A patent/EP3652148B1/en active Active
- 2018-07-09 JP JP2020502459A patent/JP2020528057A/ja active Pending
- 2018-07-09 CA CA3070043A patent/CA3070043A1/en active Pending
- 2018-07-09 KR KR1020207004626A patent/KR20200030106A/ko active Pending
- 2018-07-09 WO PCT/GB2018/051939 patent/WO2019016511A2/en not_active Ceased
- 2018-07-09 AU AU2018303293A patent/AU2018303293B2/en not_active Ceased
- 2018-07-09 DK DK18752193.5T patent/DK3652148T3/da active
- 2018-07-09 CN CN202211471062.1A patent/CN115819257A/zh active Pending
- 2018-07-09 US US16/631,685 patent/US11414374B2/en active Active
- 2018-07-09 CA CA3069869A patent/CA3069869A1/en active Pending
- 2018-07-09 BR BR112020001171-1A patent/BR112020001171A2/pt not_active IP Right Cessation
- 2018-07-09 WO PCT/GB2018/051940 patent/WO2019016512A1/en not_active Ceased
- 2018-07-09 CN CN201880060197.4A patent/CN111094235A/zh active Pending
- 2018-07-09 PL PL18752193T patent/PL3652148T3/pl unknown
- 2018-07-09 EP EP18752192.7A patent/EP3655386A2/en not_active Withdrawn
- 2018-07-09 IL IL272109A patent/IL272109B2/en unknown
-
2020
- 2020-01-15 MX MX2022013014A patent/MX2022013014A/es unknown
- 2020-01-17 IL IL272108A patent/IL272108A/en unknown
-
2023
- 2023-05-08 JP JP2023076831A patent/JP2023103328A/ja active Pending
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