DK3652148T3 - Amorf form af vilanterol-trifenatat samt fremgangsmåde til fremstilling deraf - Google Patents
Amorf form af vilanterol-trifenatat samt fremgangsmåde til fremstilling deraf Download PDFInfo
- Publication number
- DK3652148T3 DK3652148T3 DK18752193.5T DK18752193T DK3652148T3 DK 3652148 T3 DK3652148 T3 DK 3652148T3 DK 18752193 T DK18752193 T DK 18752193T DK 3652148 T3 DK3652148 T3 DK 3652148T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- amorphous form
- vilanterol triphenate
- triphenate
- vilanterol
- Prior art date
Links
- DAFYYTQWSAWIGS-DEOSSOPVSA-N vilanterol Chemical compound C1=C(O)C(CO)=CC([C@@H](O)CNCCCCCCOCCOCC=2C(=CC=CC=2Cl)Cl)=C1 DAFYYTQWSAWIGS-DEOSSOPVSA-N 0.000 title 1
- 229960004026 vilanterol Drugs 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
- C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
- C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT110209A PT110209B (pt) | 2017-07-19 | 2017-07-19 | Formas polimórficas de trifenatato de vilanterol e processos para a preparação das mesmas. |
| PCT/GB2018/051940 WO2019016512A1 (en) | 2017-07-19 | 2018-07-09 | POLYMORPHIC FORM OF VILANTEROL TRIFENATATE AND METHODS OF PREPARATION THEREOF |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3652148T3 true DK3652148T3 (da) | 2021-11-15 |
Family
ID=63143265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18752193.5T DK3652148T3 (da) | 2017-07-19 | 2018-07-09 | Amorf form af vilanterol-trifenatat samt fremgangsmåde til fremstilling deraf |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11434194B2 (da) |
| EP (2) | EP3655386A2 (da) |
| JP (2) | JP2020528057A (da) |
| KR (2) | KR20200030106A (da) |
| CN (3) | CN111108091B (da) |
| AU (2) | AU2018303782B9 (da) |
| BR (1) | BR112020001171A2 (da) |
| CA (2) | CA3069869A1 (da) |
| DK (1) | DK3652148T3 (da) |
| ES (1) | ES2899367T3 (da) |
| HU (1) | HUE056419T2 (da) |
| IL (3) | IL298421A (da) |
| MX (1) | MX2022013014A (da) |
| PL (1) | PL3652148T3 (da) |
| PT (1) | PT110209B (da) |
| WO (2) | WO2019016511A2 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT110209B (pt) | 2017-07-19 | 2021-05-17 | Hovione Farm Sa | Formas polimórficas de trifenatato de vilanterol e processos para a preparação das mesmas. |
| EP4013398A4 (en) * | 2019-08-16 | 2023-12-27 | Melody Healthcare Pvt. Ltd. | IMPROVED METHOD FOR PRODUCING VILANTEROL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF |
| CN116199590A (zh) * | 2022-12-26 | 2023-06-02 | 湖北美林药业有限公司 | 一种盐酸多巴酚丁胺及其注射剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2438985T3 (es) * | 2001-09-14 | 2014-01-21 | Glaxo Group Limited | Formulación de inhalación que comprende derivados de fenetanolamina para el tratamiento de enfermedades respiratorias |
| US20150239862A1 (en) * | 2012-09-13 | 2015-08-27 | Perrigo Api Ltd. | Process for the preparation of vilanterol and intermediates thereof |
| ES2775606T3 (es) | 2014-05-28 | 2020-07-27 | Glaxosmithkline Ip Dev Ltd | Furoato de fluticasona en el tratamiento de la EPOC |
| WO2017001907A1 (en) * | 2015-06-29 | 2017-01-05 | Teva Pharmaceuticals International Gmbh | Biocatalytic processes for the preparation of vilanterol |
| PT110209B (pt) | 2017-07-19 | 2021-05-17 | Hovione Farm Sa | Formas polimórficas de trifenatato de vilanterol e processos para a preparação das mesmas. |
-
2017
- 2017-07-19 PT PT110209A patent/PT110209B/pt active IP Right Grant
-
2018
- 2018-07-09 CN CN201880060726.0A patent/CN111108091B/zh active Active
- 2018-07-09 ES ES18752193T patent/ES2899367T3/es active Active
- 2018-07-09 DK DK18752193.5T patent/DK3652148T3/da active
- 2018-07-09 EP EP18752192.7A patent/EP3655386A2/en active Pending
- 2018-07-09 IL IL298421A patent/IL298421A/en unknown
- 2018-07-09 US US16/631,683 patent/US11434194B2/en active Active
- 2018-07-09 CA CA3069869A patent/CA3069869A1/en active Pending
- 2018-07-09 PL PL18752193T patent/PL3652148T3/pl unknown
- 2018-07-09 CN CN202211471062.1A patent/CN115819257A/zh active Pending
- 2018-07-09 KR KR1020207004626A patent/KR20200030106A/ko not_active Application Discontinuation
- 2018-07-09 AU AU2018303782A patent/AU2018303782B9/en active Active
- 2018-07-09 CN CN201880060197.4A patent/CN111094235A/zh active Pending
- 2018-07-09 US US16/631,685 patent/US11414374B2/en active Active
- 2018-07-09 KR KR1020207004628A patent/KR102572035B1/ko active IP Right Grant
- 2018-07-09 EP EP18752193.5A patent/EP3652148B1/en active Active
- 2018-07-09 JP JP2020502459A patent/JP2020528057A/ja active Pending
- 2018-07-09 BR BR112020001171-1A patent/BR112020001171A2/pt active Search and Examination
- 2018-07-09 WO PCT/GB2018/051939 patent/WO2019016511A2/en unknown
- 2018-07-09 IL IL272109A patent/IL272109B2/en unknown
- 2018-07-09 WO PCT/GB2018/051940 patent/WO2019016512A1/en active Search and Examination
- 2018-07-09 AU AU2018303293A patent/AU2018303293B2/en active Active
- 2018-07-09 CA CA3070043A patent/CA3070043A1/en active Pending
- 2018-07-09 HU HUE18752193A patent/HUE056419T2/hu unknown
-
2020
- 2020-01-15 MX MX2022013014A patent/MX2022013014A/es unknown
- 2020-01-17 IL IL272108A patent/IL272108A/en unknown
-
2023
- 2023-05-08 JP JP2023076831A patent/JP2023103328A/ja active Pending
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