PL3370698T3 - Kompozyty polimerowe zol-żel i ich zastosowania - Google Patents

Kompozyty polimerowe zol-żel i ich zastosowania

Info

Publication number
PL3370698T3
PL3370698T3 PL16805561T PL16805561T PL3370698T3 PL 3370698 T3 PL3370698 T3 PL 3370698T3 PL 16805561 T PL16805561 T PL 16805561T PL 16805561 T PL16805561 T PL 16805561T PL 3370698 T3 PL3370698 T3 PL 3370698T3
Authority
PL
Poland
Prior art keywords
sol
gel polymer
polymer composites
composites
gel
Prior art date
Application number
PL16805561T
Other languages
English (en)
Inventor
Sumitra RAJAGOPALAN
Wilms BAILLE
Piotr KUJAWA
Christopher A. Zook
Rebecca R. QUESNELL
Dennis L. Huczek
Stephen L. Secreast
Laibin Luo
Tammy A. Sanders
Original Assignee
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of PL3370698T3 publication Critical patent/PL3370698T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0041Mammary glands, e.g. breasts, udder; Intramammary administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Polymers & Plastics (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Communicable Diseases (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
PL16805561T 2015-11-03 2016-11-02 Kompozyty polimerowe zol-żel i ich zastosowania PL3370698T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562250126P 2015-11-03 2015-11-03
US201662315756P 2016-03-31 2016-03-31
PCT/US2016/060015 WO2017079216A1 (en) 2015-11-03 2016-11-02 Sol-gel polymer composites and uses thereof
EP16805561.4A EP3370698B1 (en) 2015-11-03 2016-11-02 Sol-gel polymer composites and uses thereof

Publications (1)

Publication Number Publication Date
PL3370698T3 true PL3370698T3 (pl) 2022-04-25

Family

ID=57471981

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16805561T PL3370698T3 (pl) 2015-11-03 2016-11-02 Kompozyty polimerowe zol-żel i ich zastosowania

Country Status (16)

Country Link
US (2) US10064870B2 (pl)
EP (1) EP3370698B1 (pl)
JP (1) JP6864001B2 (pl)
KR (1) KR102145435B1 (pl)
CN (1) CN108601723B (pl)
AU (1) AU2016350868B2 (pl)
BR (1) BR112018009010B1 (pl)
CA (1) CA3002214C (pl)
CL (1) CL2018001194A1 (pl)
ES (1) ES2907686T3 (pl)
MX (1) MX2018005547A (pl)
PL (1) PL3370698T3 (pl)
PT (1) PT3370698T (pl)
RU (1) RU2761212C2 (pl)
UY (1) UY36973A (pl)
WO (1) WO2017079216A1 (pl)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201116559D0 (en) 2011-09-26 2011-11-09 Univ Leuven Kath Novel viral replication inhibitors
JOP20160086B1 (ar) 2015-05-08 2021-08-17 2 Katholieke Univ Leuven Ku Leuven Research And Development مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
JO3633B1 (ar) 2015-09-16 2020-08-27 Katholieke Univ Leuven Ku Leuven Research & Development مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
JOP20160198B1 (ar) 2015-09-16 2022-03-14 Janssen Pharmaceuticals Inc مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
CA3015846A1 (en) 2016-03-18 2017-09-21 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Method for accelerating involution and preventing infection of the mammary gland at drying-off
WO2017167950A1 (en) 2016-03-31 2017-10-05 Janssen Pharmaceuticals, Inc. Substituted indole derivatives as dengue viral replication inhibitors
CR20180496A (es) 2016-03-31 2018-12-06 Univ Leuven Kath Derivados de indolina sustituidos como inhibidores de la replicación vírica de dengue
US10730884B2 (en) 2016-04-01 2020-08-04 Janssen Pharmaceuticals, Inc. Substituted indole compound derivatives as dengue viral replication inhibitors
JOP20170069B1 (ar) 2016-04-01 2021-08-17 1 Janssen Pharmaceuticals Inc مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
JOP20180026A1 (ar) 2017-03-31 2019-01-30 Univ Leuven Kath مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
JOP20180025B1 (ar) 2017-03-31 2021-08-17 Janssen Pharmaceuticals Inc مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
EP3612155A1 (en) * 2017-04-20 2020-02-26 Zoetis Services LLC Veterinary compositions for use in treating mastitis, and associated methods
WO2018215315A1 (en) 2017-05-22 2018-11-29 Janssen Pharmaceuticals, Inc. Substituted indoline derivatives as dengue viral replication inhibitors
BR112019024311A2 (pt) 2017-05-22 2020-07-28 Janssen Pharmaceuticals, Inc. derivados de indolina substituídos como inibidores da replicação viral do dengue
CA3066243A1 (en) * 2017-06-09 2018-12-13 Zoetis Broomhill Ip Limited Intramammary veterinary composition
CN109575484A (zh) * 2017-09-29 2019-04-05 天津城建大学 新型埃洛石/聚乙烯醇复合气凝胶及其制备方法和应用
US20190167714A1 (en) * 2017-12-01 2019-06-06 Zoetis Services Llc Hydrogel compositions and uses thereof
EP3740156A1 (en) * 2018-01-18 2020-11-25 Zoetis Broomhill IP Limited Internal teat sealants and their use in the prevention of bovine mastitis in the dry cow
KR102624072B1 (ko) * 2018-11-22 2024-01-11 각코우호우진 지치 이카다이가쿠 내시경 시야 확보용의 점탄성 조성물
WO2020118660A1 (en) * 2018-12-14 2020-06-18 Ecolab Usa Inc. Stable iodine-containing antimicrobial teat dip compositions
CN110437471B (zh) * 2019-07-11 2022-02-15 郑州轻工业学院 一种粘性复合水凝胶及其制备方法和用途
CN115003626A (zh) * 2019-12-20 2022-09-02 威利纳米有限公司 纳米结构二元凝胶组合物及其用途
CN111012947B (zh) * 2019-12-30 2021-11-12 南京财经大学 一种可注射和自愈合淀粉基水凝胶及其制备方法和应用
CN111214699A (zh) * 2020-01-08 2020-06-02 广州贝奥吉因生物科技股份有限公司 一种用于周围神经损伤修复的水凝胶及其制备方法
CN111840212B (zh) * 2020-06-18 2023-07-21 余祖功 一种非人类动物用乳头封闭剂及其制备方法
CN111825858B (zh) * 2020-07-02 2023-04-25 南京师范大学 一种基于两性离子和角蛋白的复合水凝胶及其制备方法
WO2022217069A1 (en) * 2021-04-09 2022-10-13 Colorado School Of Mines Radical crosslinked zwitterionic gels and uses thereof
WO2022229965A1 (en) * 2021-04-28 2022-11-03 Mileutis Ltd. Compositions and methods for modulating mammary disorders and conditions
CN113736435B (zh) * 2021-10-08 2023-05-12 扬州工业职业技术学院 一种钻井液用纳米微乳液封堵剂及其制备方法
CN114539574B (zh) * 2022-02-28 2023-06-06 浙江农林大学 压电-摩擦电耦合感应材料的制备方法和应用
CN115990275A (zh) * 2022-10-08 2023-04-21 江苏省人民医院(南京医科大学第一附属医院) 一种黏膜下注射剂及其制备方法
CN115645635A (zh) * 2022-10-24 2023-01-31 杭州旸顺医疗科技有限公司 一种液相栓塞剂及其制备方法和用途
CN115804870B (zh) * 2022-12-02 2023-12-19 浙江大学 一种微创注射生物支架及其制造方法与应用
WO2024123809A1 (en) * 2022-12-06 2024-06-13 Tricol Biomedical, Inc. Flowable chitosan bioadhesive hemostatic compositions that resist dissolution

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4333484A (en) 1978-08-02 1982-06-08 Philip Morris Incorporated Modified cellulosic smoking material and method for its preparation
ATE244584T1 (de) 1995-01-16 2003-07-15 Baxter Int Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen
DK0971690T4 (en) 1996-12-18 2015-07-13 Bimeda Res & Dev Ltd Anti-infective intramammary veterinary composition.
CA2212300A1 (en) * 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
AU1375301A (en) 1999-11-15 2001-05-30 Bio Syntech Canada Inc Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
EP1255576B1 (en) 1999-12-09 2003-08-20 Biosyntech Canada Inc. Mineral-polymer hybrid composition
US20040047892A1 (en) 2000-11-15 2004-03-11 Desrosiers Eric Andre Filler composition for soft tissue augmentation and reconstructive surgery
AU2002334349B2 (en) 2001-09-10 2008-05-15 Bimeda Research & Development Limited A bio-security system
KR100474945B1 (ko) 2002-01-10 2005-03-10 알앤엘생명과학주식회사 젖소의 원유 중 체세포 감소용 및 유방염의 예방 또는치료용 조성물
MXPA06001192A (es) * 2003-07-31 2006-04-11 Pharmacia & Upjohn Co Llc Composicion farmaceutica dispersable para el tratamiento de mastitis y trastornos oticos.
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US7828765B2 (en) 2004-02-02 2010-11-09 Bimeda Research & Development Ltd Method and device for administering two components into the teat canal of a non-human animal
US20050191270A1 (en) * 2004-02-27 2005-09-01 Hydromer, Inc. Anti-infectious hydrogel compositions
SI1836239T1 (sl) * 2005-01-13 2009-04-30 Cinv Ag Kompozitni materiali, ki vsebujejo ogljikove nanodelce
BRPI0606130A2 (pt) * 2005-02-03 2009-06-02 Cinv Ag materiais de administração de fármacos feitos através de tecnologia sol/gel
US9205046B2 (en) 2005-04-25 2015-12-08 The Governing Council Of The University Of Toronto Enhanced stability of inverse thermal gelling composite hydrogels
US8323683B2 (en) 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
WO2007066837A1 (en) 2005-12-06 2007-06-14 Lg Household & Health Care Ltd. Delivery system for tooth whitening component using in situ gelling
CA2656278C (en) 2006-06-30 2016-02-09 Biomimetic Therapeutics, Inc. Compositions and methods for treating rotator cuff injuries
NZ549249A (en) 2006-08-18 2009-10-30 Univ Massey Methods for reducing the incidence of mastitis by administration of keratin
NZ576223A (en) 2006-10-10 2012-04-27 Wisconsin Alumni Res Found Intra-mammary teat sealant formulation and method of using same to reduce or eliminate visual defects in aged cheeses
WO2008152444A2 (en) 2006-11-29 2008-12-18 Foamix Ltd. Foamable waterless compositions with modulating agents
JP5539727B2 (ja) * 2006-12-11 2014-07-02 チット2ジェル リミテッド ヒドロゲルを形成する新規な注入可能なキトサン混合物
US9034348B2 (en) 2006-12-11 2015-05-19 Chi2Gel Ltd. Injectable chitosan mixtures forming hydrogels
US8153612B2 (en) 2006-12-11 2012-04-10 Chi2Gel Ltd. Injectable chitosan mixtures forming hydrogels
EP2337544A2 (en) 2007-04-30 2011-06-29 Living Proof, Inc. Use of matrix metalloproteinase inhibitors in skin care
CN101077377A (zh) * 2007-05-09 2007-11-28 史义林 防治牛、羊乳房炎的复方碘化壳聚糖涂膜剂及其制备方法
US20090081173A1 (en) 2007-08-10 2009-03-26 The Board Of Regents Of The University Of Texas System Methods and compositions involving bacteriophage isolates
GB2459910B (en) * 2008-04-21 2010-03-31 Otonomy Inc Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
US8318817B2 (en) * 2008-07-21 2012-11-27 Otonomy, Inc. Controlled release antimicrobial compositions and methods for the treatment of otic disorders
JP5722782B2 (ja) * 2008-09-26 2015-05-27 ナノバイオ コーポレーション ナノエマルジョン治療用組成物及びその使用方法
EP3158868A1 (en) * 2008-12-04 2017-04-26 Merial, Inc Intramammary teat sealant
WO2010065908A2 (en) * 2008-12-05 2010-06-10 Catchmark Jeffrey M Degradable biomolecule compositions
JP5597204B2 (ja) 2008-12-16 2014-10-01 カールスベア アー/エス 気相グラフティングによってヒドロキシル化された表面のコーティング
CA2747508A1 (en) 2008-12-19 2010-06-24 Biomimetic Therapeutics, Inc. Bone grafts with reduced protease activity and methods of selection and use
WO2011022071A2 (en) 2009-08-20 2011-02-24 The Regents Of The University Of California Cardiac compositions
CN101664381A (zh) * 2009-08-21 2010-03-10 天津生机集团股份有限公司 治疗奶牛乳房炎的原位凝胶缓释制剂的制备方法
CN102125516B (zh) * 2010-01-13 2014-03-26 北京大学 温敏型原位凝胶药物组合物
AU2011291537B2 (en) 2010-08-19 2016-06-02 The Regents Of The University Of California Compositions comprising perivascular stem cells and Nell-1 protein
US20130287930A1 (en) 2010-12-16 2013-10-31 Specialites Pet Food Method for producing highly palatable dry cat food
GB201113606D0 (en) 2011-08-05 2011-09-21 Norbrook Lab Ltd Dual chamber syringe
US20130108683A1 (en) 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating partial and full thickness wounds and injuries
US20130108670A1 (en) 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating full thickness burn injuries
US9963627B2 (en) 2012-11-09 2018-05-08 Bioastra Technologies Inc. Nanostructured phase change materials for solid state thermal management
RU2521401C1 (ru) * 2012-12-07 2014-06-27 ГНУ Краснодарский научно-исследовательский ветеринарный институт Российская академия сельскохозяйственных наук (Краснодарский НИВИ) Средство для профилактики мастита у дойных коров в сухостойный период
EP2970382B1 (en) 2013-03-13 2019-09-25 Anteis SA Peptides for skin rejuvenation and methods of using the same
WO2014152959A1 (en) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
CA3131352A1 (en) 2013-03-15 2014-09-18 Human Biomolecular Research Institute Compounds and matrices for use in bone growth and repair
EP2970586B1 (en) * 2013-03-15 2022-12-07 Genzyme Corporation Amine functional polyamides
TW201532621A (zh) 2013-04-22 2015-09-01 Neocutis Sa 抗氧化劑組成物及其使用方法
CN103381139A (zh) 2013-05-10 2013-11-06 南京农业大学 黄芪多糖注射用原位凝胶及其制备方法
AU2014318264B2 (en) 2013-09-16 2018-10-04 Zoetis Services Llc Assembly for sequentially delivering substances, and associated methods
CN104510729A (zh) 2013-09-26 2015-04-15 黄永 激活动物免疫抗性的脂肪酸及其衍生物的组合物
EP3200843A4 (en) 2014-10-03 2018-06-20 Cytori Therapeutics, Inc. Use of regenerative cells in mitigating burn progression and improving skin graft incorporation and healing

Also Published As

Publication number Publication date
CA3002214C (en) 2022-01-04
CA3002214A1 (en) 2017-05-11
US20190030043A1 (en) 2019-01-31
AU2016350868A1 (en) 2018-05-10
AU2016350868B2 (en) 2022-03-31
BR112018009010A2 (pt) 2018-10-30
KR20180075646A (ko) 2018-07-04
EP3370698B1 (en) 2022-01-26
EP3370698A1 (en) 2018-09-12
JP2018536708A (ja) 2018-12-13
JP6864001B2 (ja) 2021-04-21
BR112018009010A8 (pt) 2019-02-26
KR102145435B1 (ko) 2020-08-18
US10729698B2 (en) 2020-08-04
WO2017079216A1 (en) 2017-05-11
MX2018005547A (es) 2018-11-09
US10064870B2 (en) 2018-09-04
BR112018009010B1 (pt) 2023-09-26
RU2018115574A (ru) 2019-10-25
CN108601723B (zh) 2022-05-17
US20170119785A1 (en) 2017-05-04
RU2018115574A3 (pl) 2020-03-13
RU2761212C2 (ru) 2021-12-06
UY36973A (es) 2017-06-30
CL2018001194A1 (es) 2019-05-17
ES2907686T3 (es) 2022-04-26
PT3370698T (pt) 2022-03-02
CN108601723A (zh) 2018-09-28

Similar Documents

Publication Publication Date Title
PT3370698T (pt) Compósitos de polímero sol-gel e utilizações dos mesmos
HK1231471A1 (zh) -雜芳氧基-和 芳氧基-喹啉- -甲酰胺及其用途
IL247344B (en) A new polysaccharide and its uses
SG11201702603RA (en) Organosilica materials and uses thereof
PL3152226T3 (pl) Modyfikowane cyklopentapeptydy i ich zastosowania
SG11201607082PA (en) New tetracyano-anthraquino-dimethane polymers and use thereof
GB201503393D0 (en) Polymers and uses thereof
HK1232241A1 (zh) 聚合物顆粒及其用途
EP3168250A4 (en) Fluorine-atom-containing polymer and use thereof
IL248014B (en) Nanostructures and their applications
PL3158017T3 (pl) Żywica, skład i zastosowanie
GB2514927B (en) Thiamethoxam and uses thereof
HK1247122A1 (zh) 組合及其用途
IL254241A0 (en) Etv2 and its uses
SG10201501373WA (en) Contrast Agent And Applications Thereof
IL251518B (en) Astaxanthin-based polymers and their uses
GB2530711B (en) Security composition and use thereof
GB2545167B (en) Cloches and use thereof
HUP1500514A2 (en) New ppv1 strain and uses thereof
GB201513221D0 (en) Silicone polymer blend composites
GB201413288D0 (en) Silicone polymer blend composites
GB201404728D0 (en) Disc-over incorporating disc-heads and disc-earning