PL3288965T3 - Rozpuszczalny chimeryczny receptor interleukiny-10 i jego zastosowanie terapeutyczne - Google Patents

Rozpuszczalny chimeryczny receptor interleukiny-10 i jego zastosowanie terapeutyczne

Info

Publication number
PL3288965T3
PL3288965T3 PL16728097T PL16728097T PL3288965T3 PL 3288965 T3 PL3288965 T3 PL 3288965T3 PL 16728097 T PL16728097 T PL 16728097T PL 16728097 T PL16728097 T PL 16728097T PL 3288965 T3 PL3288965 T3 PL 3288965T3
Authority
PL
Poland
Prior art keywords
receptor
therapeutic use
soluble chimeric
chimeric interleukin
interleukin
Prior art date
Application number
PL16728097T
Other languages
English (en)
Inventor
Gilberto Filaci
Daniela Fenoglio
Francesca Ferrera
Original Assignee
Mediolanum Farm S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farm S P A filed Critical Mediolanum Farm S P A
Publication of PL3288965T3 publication Critical patent/PL3288965T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5428IL-10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/53Hinge
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
PL16728097T 2015-04-29 2016-04-26 Rozpuszczalny chimeryczny receptor interleukiny-10 i jego zastosowanie terapeutyczne PL3288965T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITUB20150391 2015-04-29
EP16728097.3A EP3288965B1 (en) 2015-04-29 2016-04-26 A soluble chimeric interleukin-10 receptor and therapeutic use thereof
PCT/IB2016/052359 WO2016174575A1 (en) 2015-04-29 2016-04-26 A soluble chimeric interleukin-10 receptor and therapeutic use thereof

Publications (1)

Publication Number Publication Date
PL3288965T3 true PL3288965T3 (pl) 2019-11-29

Family

ID=53765409

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16728097T PL3288965T3 (pl) 2015-04-29 2016-04-26 Rozpuszczalny chimeryczny receptor interleukiny-10 i jego zastosowanie terapeutyczne

Country Status (15)

Country Link
US (1) US20180086809A1 (pl)
EP (1) EP3288965B1 (pl)
JP (1) JP2018518945A (pl)
KR (1) KR20170138569A (pl)
CN (1) CN107531771A (pl)
CA (1) CA2979973A1 (pl)
CY (1) CY1122061T1 (pl)
DK (1) DK3288965T3 (pl)
ES (1) ES2744342T3 (pl)
HK (1) HK1245814B (pl)
HU (1) HUE046343T2 (pl)
PL (1) PL3288965T3 (pl)
PT (1) PT3288965T (pl)
SI (1) SI3288965T1 (pl)
WO (1) WO2016174575A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017336546A1 (en) 2016-09-27 2019-05-02 Epicentrx, Inc. Immunomodulatory fusion proteins
KR20200057070A (ko) * 2017-09-27 2020-05-25 에피센트알엑스, 인코포레이티드 면역조절 융합 단백질
CN116125074A (zh) * 2022-12-13 2023-05-16 北京东方百泰生物科技股份有限公司 一种IL-10-Fc融合蛋白与其受体结合活性的检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789192A (en) * 1992-12-10 1998-08-04 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
US6165476A (en) * 1997-07-10 2000-12-26 Beth Israel Deaconess Medical Center Fusion proteins with an immunoglobulin hinge region linker
AU2001266557A1 (en) * 2000-04-12 2001-10-23 Human Genome Sciences, Inc. Albumin fusion proteins
WO2005024027A1 (ja) * 2003-09-02 2005-03-17 National Institute Of Advanced Industrial Science And Technology 抗体医薬
JP4870569B2 (ja) * 2003-11-13 2012-02-08 ハンミ ホールディングス カンパニー リミテッド 免疫グロブリン断片を用いた蛋白質結合体およびその製造方法
EP2162472B1 (en) * 2007-05-30 2013-02-27 Postech Academy-Industry- Foundation Immunoglobulin fusion proteins
DK2344540T3 (da) * 2008-10-02 2018-01-29 Aptevo Res & Development Llc Cd86-antagonist multimål bindingsproteiner
KR102053674B1 (ko) * 2012-05-25 2019-12-09 얀센 바이오테크 인코포레이티드 비-천연 컨센서스 알부민 결합 도메인

Also Published As

Publication number Publication date
DK3288965T3 (da) 2019-09-23
CN107531771A (zh) 2018-01-02
HK1245814B (zh) 2020-06-19
EP3288965B1 (en) 2019-06-26
CY1122061T1 (el) 2020-11-25
JP2018518945A (ja) 2018-07-19
US20180086809A1 (en) 2018-03-29
ES2744342T3 (es) 2020-02-24
EP3288965A1 (en) 2018-03-07
SI3288965T1 (sl) 2019-10-30
HUE046343T2 (hu) 2020-02-28
CA2979973A1 (en) 2016-11-03
WO2016174575A1 (en) 2016-11-03
PT3288965T (pt) 2019-10-15
KR20170138569A (ko) 2017-12-15

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