PT3288965T - Um recetor de interleucina-10 quimérico solúvel e sua utilização terapêutica - Google Patents

Um recetor de interleucina-10 quimérico solúvel e sua utilização terapêutica

Info

Publication number
PT3288965T
PT3288965T PT167280973T PT16728097T PT3288965T PT 3288965 T PT3288965 T PT 3288965T PT 167280973 T PT167280973 T PT 167280973T PT 16728097 T PT16728097 T PT 16728097T PT 3288965 T PT3288965 T PT 3288965T
Authority
PT
Portugal
Prior art keywords
receptor
therapeutic use
soluble chimeric
chimeric interleukin
interleukin
Prior art date
Application number
PT167280973T
Other languages
English (en)
Inventor
Filaci Gilberto
Fenoglio Daniela
Ferrera Francesca
Original Assignee
Mediolanum Farm S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farm S P A filed Critical Mediolanum Farm S P A
Publication of PT3288965T publication Critical patent/PT3288965T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5428—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/53—Hinge
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
PT167280973T 2015-04-29 2016-04-26 Um recetor de interleucina-10 quimérico solúvel e sua utilização terapêutica PT3288965T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUB20150391 2015-04-29

Publications (1)

Publication Number Publication Date
PT3288965T true PT3288965T (pt) 2019-10-15

Family

ID=53765409

Family Applications (1)

Application Number Title Priority Date Filing Date
PT167280973T PT3288965T (pt) 2015-04-29 2016-04-26 Um recetor de interleucina-10 quimérico solúvel e sua utilização terapêutica

Country Status (15)

Country Link
US (1) US20180086809A1 (pt)
EP (1) EP3288965B1 (pt)
JP (1) JP2018518945A (pt)
KR (1) KR20170138569A (pt)
CN (1) CN107531771A (pt)
CA (1) CA2979973A1 (pt)
CY (1) CY1122061T1 (pt)
DK (1) DK3288965T3 (pt)
ES (1) ES2744342T3 (pt)
HK (1) HK1245814B (pt)
HU (1) HUE046343T2 (pt)
PL (1) PL3288965T3 (pt)
PT (1) PT3288965T (pt)
SI (1) SI3288965T1 (pt)
WO (1) WO2016174575A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7421338B2 (ja) 2016-09-27 2024-01-24 エピセントアールエックス，インコーポレイテッド 免疫調節融合タンパク質
JP2020536518A (ja) * 2017-09-27 2020-12-17 エピセントアールエックス，インコーポレイテッド 免疫調節融合タンパク質
CN116125074A (zh) * 2022-12-13 2023-05-16 北京东方百泰生物科技股份有限公司 一种IL-10-Fc融合蛋白与其受体结合活性的检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789192A (en) * 1992-12-10 1998-08-04 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
US6165476A (en) * 1997-07-10 2000-12-26 Beth Israel Deaconess Medical Center Fusion proteins with an immunoglobulin hinge region linker
JP2003530838A (ja) * 2000-04-12 2003-10-21 ヒューマン ゲノム サイエンシズ インコーポレイテッド アルブミン融合タンパク質
JP4635255B2 (ja) * 2003-09-02 2011-02-23 独立行政法人産業技術総合研究所 抗体医薬
AU2004282984B2 (en) * 2003-11-13 2011-07-14 Hanmi Science Co., Ltd. Protein complex using immunoglobulin fragment andmethod for the preparation thereof
JP5577243B2 (ja) * 2007-05-30 2014-08-20 ポステク アカデミー−インダストリー ファウンデイション 免疫グロブリン融合タンパク質
EP3281955A1 (en) * 2008-10-02 2018-02-14 Aptevo Research and Development LLC Cd86 antagonist multi-target binding proteins
BR112014029409B1 (pt) * 2012-05-25 2022-11-29 Janssen Biotech, Inc Domínio de ligação a albumina isolado não natural, método para produção do mesmo, polinucleotídeo isolado, vetor isolado, célula hospedeira isolada, proteína de fusão e composição farmacêutica

Also Published As

Publication number Publication date
JP2018518945A (ja) 2018-07-19
CA2979973A1 (en) 2016-11-03
CY1122061T1 (el) 2020-11-25
PL3288965T3 (pl) 2019-11-29
CN107531771A (zh) 2018-01-02
EP3288965B1 (en) 2019-06-26
KR20170138569A (ko) 2017-12-15
ES2744342T3 (es) 2020-02-24
SI3288965T1 (sl) 2019-10-30
DK3288965T3 (da) 2019-09-23
HUE046343T2 (hu) 2020-02-28
EP3288965A1 (en) 2018-03-07
HK1245814B (zh) 2020-06-19
US20180086809A1 (en) 2018-03-29
WO2016174575A1 (en) 2016-11-03

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