HUE046343T2 - Oldható, kiméra interleukin-10 receptor és terápiás alkalmazása - Google Patents

Oldható, kiméra interleukin-10 receptor és terápiás alkalmazása

Info

Publication number
HUE046343T2
HUE046343T2 HUE16728097A HUE16728097A HUE046343T2 HU E046343 T2 HUE046343 T2 HU E046343T2 HU E16728097 A HUE16728097 A HU E16728097A HU E16728097 A HUE16728097 A HU E16728097A HU E046343 T2 HUE046343 T2 HU E046343T2
Authority
HU
Hungary
Prior art keywords
receptor
therapeutic use
soluble chimeric
chimeric interleukin
interleukin
Prior art date
Application number
HUE16728097A
Other languages
English (en)
Inventor
Gilberto Filaci
Daniela Fenoglio
Francesca Ferrera
Original Assignee
Mediolanum Farm S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farm S P A filed Critical Mediolanum Farm S P A
Publication of HUE046343T2 publication Critical patent/HUE046343T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5428—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/53—Hinge
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
HUE16728097A 2015-04-29 2016-04-26 Oldható, kiméra interleukin-10 receptor és terápiás alkalmazása HUE046343T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUB20150391 2015-04-29

Publications (1)

Publication Number Publication Date
HUE046343T2 true HUE046343T2 (hu) 2020-02-28

Family

ID=53765409

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16728097A HUE046343T2 (hu) 2015-04-29 2016-04-26 Oldható, kiméra interleukin-10 receptor és terápiás alkalmazása

Country Status (15)

Country Link
US (1) US20180086809A1 (hu)
EP (1) EP3288965B1 (hu)
JP (1) JP2018518945A (hu)
KR (1) KR20170138569A (hu)
CN (1) CN107531771A (hu)
CA (1) CA2979973A1 (hu)
CY (1) CY1122061T1 (hu)
DK (1) DK3288965T3 (hu)
ES (1) ES2744342T3 (hu)
HK (1) HK1245814B (hu)
HU (1) HUE046343T2 (hu)
PL (1) PL3288965T3 (hu)
PT (1) PT3288965T (hu)
SI (1) SI3288965T1 (hu)
WO (1) WO2016174575A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110546168B (zh) 2016-09-27 2024-03-15 埃皮辛特瑞柯斯公司 免疫调节性融合蛋白
KR20200057070A (ko) * 2017-09-27 2020-05-25 에피센트알엑스, 인코포레이티드 면역조절 융합 단백질
CN116125074A (zh) * 2022-12-13 2023-05-16 北京东方百泰生物科技股份有限公司 一种IL-10-Fc融合蛋白与其受体结合活性的检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789192A (en) * 1992-12-10 1998-08-04 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
US6165476A (en) * 1997-07-10 2000-12-26 Beth Israel Deaconess Medical Center Fusion proteins with an immunoglobulin hinge region linker
AU2001266557A1 (en) * 2000-04-12 2001-10-23 Human Genome Sciences, Inc. Albumin fusion proteins
WO2005024027A1 (ja) * 2003-09-02 2005-03-17 National Institute Of Advanced Industrial Science And Technology 抗体医薬
KR100775343B1 (ko) * 2003-11-13 2007-11-08 한미약품 주식회사 면역글로불린 Ｆｃ 영역을 캐리어로 포함하는 약제학적조성물
KR101380729B1 (ko) * 2007-05-30 2014-04-10 포항공과대학교 산학협력단 면역글로불린 융합 단백질
EA024877B1 (ru) * 2008-10-02 2016-10-31 Эмерджент Продакт Дивелопмент Сиэтл, Ллс Связывающие множество мишеней белки, обладающие антагонистическими свойствами по отношению к cd86
ES2670442T3 (es) * 2012-05-25 2018-05-30 Janssen Biotech, Inc. Dominios de unión a albúmina de consenso no naturales

Also Published As

Publication number Publication date
SI3288965T1 (sl) 2019-10-30
HK1245814B (zh) 2020-06-19
EP3288965B1 (en) 2019-06-26
JP2018518945A (ja) 2018-07-19
PL3288965T3 (pl) 2019-11-29
CA2979973A1 (en) 2016-11-03
EP3288965A1 (en) 2018-03-07
CN107531771A (zh) 2018-01-02
US20180086809A1 (en) 2018-03-29
DK3288965T3 (da) 2019-09-23
KR20170138569A (ko) 2017-12-15
WO2016174575A1 (en) 2016-11-03
CY1122061T1 (el) 2020-11-25
PT3288965T (pt) 2019-10-15
ES2744342T3 (es) 2020-02-24

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