PL324993A1 - Bioconjugates of macrocyclic, nitrogen containing manganese complex ligands efficiently acting as catalysts of the superoxidic dismutation reaction - Google Patents

Bioconjugates of macrocyclic, nitrogen containing manganese complex ligands efficiently acting as catalysts of the superoxidic dismutation reaction

Info

Publication number
PL324993A1
PL324993A1 PL96324993A PL32499396A PL324993A1 PL 324993 A1 PL324993 A1 PL 324993A1 PL 96324993 A PL96324993 A PL 96324993A PL 32499396 A PL32499396 A PL 32499396A PL 324993 A1 PL324993 A1 PL 324993A1
Authority
PL
Poland
Prior art keywords
superoxidic
bioconjugates
macrocyclic
catalysts
nitrogen containing
Prior art date
Application number
PL96324993A
Other languages
English (en)
Inventor
William L Neumann
Dennis P Riley
Randy H Weiss
Susan L Henke
Patrick J Lennon
Karl W Aston
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of PL324993A1 publication Critical patent/PL324993A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
PL96324993A 1995-08-17 1996-08-14 Bioconjugates of macrocyclic, nitrogen containing manganese complex ligands efficiently acting as catalysts of the superoxidic dismutation reaction PL324993A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US242195P 1995-08-17 1995-08-17
PCT/US1996/012767 WO1997006824A2 (fr) 1995-08-17 1996-08-14 Bioconjugues de complexes de manganese et leur application comme catalyseurs

Publications (1)

Publication Number Publication Date
PL324993A1 true PL324993A1 (en) 1998-07-06

Family

ID=21700675

Family Applications (1)

Application Number Title Priority Date Filing Date
PL96324993A PL324993A1 (en) 1995-08-17 1996-08-14 Bioconjugates of macrocyclic, nitrogen containing manganese complex ligands efficiently acting as catalysts of the superoxidic dismutation reaction

Country Status (12)

Country Link
EP (1) EP0844886A2 (fr)
JP (1) JP2000513322A (fr)
KR (1) KR19990037647A (fr)
CN (1) CN1200039A (fr)
AU (1) AU700958B2 (fr)
BR (1) BR9610347A (fr)
CA (1) CA2229799A1 (fr)
CZ (1) CZ39898A3 (fr)
IL (1) IL123040A0 (fr)
NO (1) NO980649L (fr)
PL (1) PL324993A1 (fr)
WO (1) WO1997006824A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01007451A (es) 1999-01-25 2004-03-10 Nat Jewish Med & Res Center Porfirinas sustituidas.
AU2206401A (en) * 1999-12-23 2001-07-09 Amersham Plc Labelled ascorbic acid derivatives
US20050176790A1 (en) 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
WO2002098431A1 (fr) 2001-06-01 2002-12-12 National Jewish Medical And Research Center Capteurs oxydants destines au traitement du diabete ou a etre utilises dans une transplantation ou a induire une tolerance immunitaire
KR20140001257A (ko) 2008-05-13 2014-01-06 유니버시티 오브 캔사스 금속 추출 펩타이드(ｍａｐ) 태그 및 관련된 방법
RU2506083C2 (ru) 2008-05-23 2014-02-10 Нэшнл Джуиш Хелт Способ лечения поражений, ассоциированных с воздействием алкилирующих веществ
CN103906756B (zh) * 2011-09-26 2020-03-03 加莱拉实验室有限责任公司 用于治疗疾病的方法
US9187735B2 (en) 2012-06-01 2015-11-17 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
JP2020507598A (ja) * 2017-02-15 2020-03-12 ガレラ・ラブス・リミテッド・ライアビリティ・カンパニーＧａｌｅｒａ Ｌａｂｓ， Ｌｌｃ 局所腸送達のためのペンタアザマクロ環錯体
CN108752383B (zh) * 2018-05-02 2020-10-30 江苏理工学院 一种具有sod活性的吡唑羧酸酯锰配合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283904C (fr) * 1987-03-06 1991-05-07 Mitsuaki Maeda Complexe de platine (ii) liposoluble, et sa preparation
WO1993002090A1 (fr) * 1991-07-19 1993-02-04 Monsanto Company Complexes manganeseux de ligands macrocycliques azotes efficaces comme catalyseurs pour dismuter le superoxyde
US6204259B1 (en) * 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
NZ283279A (en) * 1994-04-22 1998-01-26 Monsanto Co Magnetic resonance imaging compounds comprising paramagnetic metals, compositions and use thereof
US6525041B1 (en) * 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
WO1996040658A1 (fr) * 1995-06-07 1996-12-19 Monsanto Company Procede de preparation de polyazamacrocycles substitues

Also Published As

Publication number Publication date
AU700958B2 (en) 1999-01-14
BR9610347A (pt) 1999-06-01
CN1200039A (zh) 1998-11-25
WO1997006824A3 (fr) 1997-07-03
EP0844886A2 (fr) 1998-06-03
CA2229799A1 (fr) 1997-02-27
CZ39898A3 (cs) 1998-07-15
IL123040A0 (en) 1998-09-24
MX9801322A (es) 1998-05-31
NO980649D0 (no) 1998-02-16
JP2000513322A (ja) 2000-10-10
KR19990037647A (ko) 1999-05-25
WO1997006824A2 (fr) 1997-02-27
NO980649L (no) 1998-04-02
AU6765596A (en) 1997-03-12

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