PL324993A1 - Bioconjugates of macrocyclic, nitrogen containing manganese complex ligands efficiently acting as catalysts of the superoxidic dismutation reaction - Google Patents

Bioconjugates of macrocyclic, nitrogen containing manganese complex ligands efficiently acting as catalysts of the superoxidic dismutation reaction

Info

Publication number
PL324993A1
PL324993A1 PL96324993A PL32499396A PL324993A1 PL 324993 A1 PL324993 A1 PL 324993A1 PL 96324993 A PL96324993 A PL 96324993A PL 32499396 A PL32499396 A PL 32499396A PL 324993 A1 PL324993 A1 PL 324993A1
Authority
PL
Poland
Prior art keywords
superoxidic
bioconjugates
macrocyclic
catalysts
nitrogen containing
Prior art date
Application number
PL96324993A
Other languages
English (en)
Inventor
William L Neumann
Dennis P Riley
Randy H Weiss
Susan L Henke
Patrick J Lennon
Karl W Aston
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of PL324993A1 publication Critical patent/PL324993A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
PL96324993A 1995-08-17 1996-08-14 Bioconjugates of macrocyclic, nitrogen containing manganese complex ligands efficiently acting as catalysts of the superoxidic dismutation reaction PL324993A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US242195P 1995-08-17 1995-08-17
PCT/US1996/012767 WO1997006824A2 (en) 1995-08-17 1996-08-14 Bioconjugates of manganese complexes and their application as catalysts

Publications (1)

Publication Number Publication Date
PL324993A1 true PL324993A1 (en) 1998-07-06

Family

ID=21700675

Family Applications (1)

Application Number Title Priority Date Filing Date
PL96324993A PL324993A1 (en) 1995-08-17 1996-08-14 Bioconjugates of macrocyclic, nitrogen containing manganese complex ligands efficiently acting as catalysts of the superoxidic dismutation reaction

Country Status (12)

Country Link
EP (1) EP0844886A2 (xx)
JP (1) JP2000513322A (xx)
KR (1) KR19990037647A (xx)
CN (1) CN1200039A (xx)
AU (1) AU700958B2 (xx)
BR (1) BR9610347A (xx)
CA (1) CA2229799A1 (xx)
CZ (1) CZ39898A3 (xx)
IL (1) IL123040A0 (xx)
NO (1) NO980649L (xx)
PL (1) PL324993A1 (xx)
WO (1) WO1997006824A2 (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1155019T3 (da) 1999-01-25 2006-04-18 Nat Jewish Med & Res Center Substituerede porphyriner og deres terapeutiske anvendelse
WO2001047564A2 (en) * 1999-12-23 2001-07-05 Amersham Plc Labelled ascorbic acid derivatives
US20050176790A1 (en) 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
EP1439842A4 (en) 2001-06-01 2009-09-02 Nat Jewish Med & Res Center OXIDANT CAPTAIN FOR THE TREATMENT OF DIABETES OR FOR THE USE IN THE TRANSPLANTATION OR INDUCTION OF IMMUNOTOLERANE
EP2300032A4 (en) 2008-05-13 2012-12-05 Univ Kansas MARKER PRESENTING IN THE FORM OF A MAP PEPTIDE (METAL ABSTRACTION PEPTIDE) AND ASSOCIATED METHODS
ES2600469T3 (es) 2008-05-23 2017-02-09 National Jewish Health Un compuesto para su uso en el tratamiento de lesiones asociadas con la exposición al gas fosgeno o al gas de cloro
WO2013048965A1 (en) * 2011-09-26 2013-04-04 Galera Therapeutics, Llc Methods for treatment of diseases
US9187735B2 (en) 2012-06-01 2015-11-17 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
WO2018152353A2 (en) * 2017-02-15 2018-08-23 Galera Labs, Llc Pentaaza macrocyclic ring complexes for local intestinal delivery
CN108752383B (zh) * 2018-05-02 2020-10-30 江苏理工学院 一种具有sod活性的吡唑羧酸酯锰配合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0281463A3 (en) * 1987-03-06 1989-01-25 Sumitomo Pharmaceuticals Company, Limited Platinum complex, process for its preparation and pharmaceutical composition including such a complex
DE69224839T2 (de) * 1991-07-19 1998-10-08 Monsanto Co Mangan-Komplexe mit Stickstoff enthaltenden makrozyklischen Liganden, wirksam als Superoxiddismutasekatalysatoren.
US6204259B1 (en) * 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
PL316968A1 (en) * 1994-04-22 1997-03-03 Monsanto Co Method of analysing diagnostic images employing the metal complexes with nitrogen containing macrocyclic ligands
US6525041B1 (en) * 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
JPH11507621A (ja) * 1995-06-07 1999-07-06 モンサント カンパニー 置換ポリアザ大環状化合物の製造法

Also Published As

Publication number Publication date
AU700958B2 (en) 1999-01-14
NO980649D0 (no) 1998-02-16
CA2229799A1 (en) 1997-02-27
AU6765596A (en) 1997-03-12
JP2000513322A (ja) 2000-10-10
CZ39898A3 (cs) 1998-07-15
IL123040A0 (en) 1998-09-24
WO1997006824A3 (en) 1997-07-03
KR19990037647A (ko) 1999-05-25
MX9801322A (es) 1998-05-31
CN1200039A (zh) 1998-11-25
NO980649L (no) 1998-04-02
BR9610347A (pt) 1999-06-01
EP0844886A2 (en) 1998-06-03
WO1997006824A2 (en) 1997-02-27

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