PL3247388T3 - Rekombinowany ludzki/bydlęcy wirus paragrypy 3 (b/hpiv3) eksprymujący chimeryczne białko f rsv/bpiv3 i jego zastosowania - Google Patents
Rekombinowany ludzki/bydlęcy wirus paragrypy 3 (b/hpiv3) eksprymujący chimeryczne białko f rsv/bpiv3 i jego zastosowaniaInfo
- Publication number
- PL3247388T3 PL3247388T3 PL16702318.3T PL16702318T PL3247388T3 PL 3247388 T3 PL3247388 T3 PL 3247388T3 PL 16702318 T PL16702318 T PL 16702318T PL 3247388 T3 PL3247388 T3 PL 3247388T3
- Authority
- PL
- Poland
- Prior art keywords
- bpiv3
- hpiv3
- expressing
- protein
- recombinant human
- Prior art date
Links
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/033—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the internal surface of the plasma membrane, e.g. containing a myristoylation motif
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18571—Demonstrated in vivo effect
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18621—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18641—Use of virus, viral particle or viral elements as a vector
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18641—Use of virus, viral particle or viral elements as a vector
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
- C12N2760/18722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
- C12N2760/18734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
- C12N2760/18741—Use of virus, viral particle or viral elements as a vector
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
- C12N2760/18741—Use of virus, viral particle or viral elements as a vector
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
- C12N2760/18771—Demonstrated in vivo effect
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- Health & Medical Sciences (AREA)
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- General Engineering & Computer Science (AREA)
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562105667P | 2015-01-20 | 2015-01-20 | |
| PCT/US2016/014154 WO2016118642A1 (en) | 2015-01-20 | 2016-01-20 | Recombinant human/bovine parainfluenza virus 3 (b/hpiv3) expressing a chimeric rsv/bpiv3 f protein and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3247388T3 true PL3247388T3 (pl) | 2026-02-09 |
Family
ID=55272724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16702318.3T PL3247388T3 (pl) | 2015-01-20 | 2016-01-20 | Rekombinowany ludzki/bydlęcy wirus paragrypy 3 (b/hpiv3) eksprymujący chimeryczne białko f rsv/bpiv3 i jego zastosowania |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US10654898B2 (pl) |
| EP (1) | EP3247388B1 (pl) |
| JP (3) | JP7020917B2 (pl) |
| CN (1) | CN107406835A (pl) |
| CA (1) | CA2974359A1 (pl) |
| DK (1) | DK3247388T3 (pl) |
| FI (1) | FI3247388T3 (pl) |
| LT (1) | LT3247388T (pl) |
| PL (1) | PL3247388T3 (pl) |
| PT (1) | PT3247388T (pl) |
| RS (1) | RS67526B1 (pl) |
| WO (1) | WO2016118642A1 (pl) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3247388T3 (pl) | 2015-01-20 | 2026-02-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rekombinowany ludzki/bydlęcy wirus paragrypy 3 (b/hpiv3) eksprymujący chimeryczne białko f rsv/bpiv3 i jego zastosowania |
| WO2018081289A2 (en) | 2016-10-25 | 2018-05-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Prefusion piv f immunogens and their use |
| WO2018222573A1 (en) | 2017-05-29 | 2018-12-06 | The United State Of America, As Represented By The Secretary, Department Of Health & Human Services | Recombinant chimeric bovine/human parainfluenza virus 3 expressing rsv g and its use |
| CN112262215B (zh) | 2018-04-23 | 2025-03-18 | 美国卫生和人力服务部 | 嵌合载体 |
| KR102567994B1 (ko) * | 2018-10-12 | 2023-08-17 | 에스케이바이오사이언스(주) | 재조합 rsv 생백신주 및 이의 제조 방법 |
| GB201816873D0 (en) * | 2018-10-17 | 2018-11-28 | Imperial Innovations Ltd | Fusion protein |
| WO2021026175A1 (en) * | 2019-08-05 | 2021-02-11 | Icahn School Of Medicine At Mount Sinai | Peptides that block presentation of antigenic islet peptides by hla-dq8 and methods for treating type-1 diabetes |
| WO2021248086A2 (en) * | 2020-06-05 | 2021-12-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Live attenuated respiratory syncytial virus |
| WO2022175479A1 (en) * | 2021-02-19 | 2022-08-25 | Janssen Vaccines & Prevention B.V. | Vaccine combinations against respiratory syncytial virus strain a and b infections |
| US20240197861A1 (en) | 2021-04-27 | 2024-06-20 | The U.S.A., As Represented By The Secretary, Department Of Health And Human Services | Recombinant chimeric bovine/human parainfluenza virus 3 expressing sars-cov-2 spike protein and its use |
| CN113322241B (zh) * | 2021-05-14 | 2023-06-13 | 金宇保灵生物药品有限公司 | 一种牛副流感病毒3型病毒株bpiv3-nm及其应用 |
| WO2023288296A1 (en) * | 2021-07-15 | 2023-01-19 | Board Of Regents, The University Of Texas System | Prefusion-stabilized chimeric hmpv-rsv f proteins |
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2016
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- 2016-01-20 FI FIEP16702318.3T patent/FI3247388T3/fi active
- 2016-01-20 US US15/545,218 patent/US10654898B2/en active Active
- 2016-01-20 CN CN201680012795.5A patent/CN107406835A/zh active Pending
- 2016-01-20 RS RS20251276A patent/RS67526B1/sr unknown
- 2016-01-20 EP EP16702318.3A patent/EP3247388B1/en active Active
- 2016-01-20 WO PCT/US2016/014154 patent/WO2016118642A1/en not_active Ceased
- 2016-01-20 DK DK16702318.3T patent/DK3247388T3/da active
- 2016-01-20 PT PT167023183T patent/PT3247388T/pt unknown
- 2016-01-20 CA CA2974359A patent/CA2974359A1/en active Pending
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| US20200277338A1 (en) | 2020-09-03 |
| JP7020917B2 (ja) | 2022-02-16 |
| JP2024054235A (ja) | 2024-04-16 |
| JP2022062158A (ja) | 2022-04-19 |
| LT3247388T (lt) | 2025-12-29 |
| JP2018503402A (ja) | 2018-02-08 |
| PT3247388T (pt) | 2026-01-12 |
| FI3247388T3 (fi) | 2025-12-08 |
| DK3247388T3 (da) | 2025-12-22 |
| US11591372B2 (en) | 2023-02-28 |
| US20180312544A1 (en) | 2018-11-01 |
| CA2974359A1 (en) | 2016-07-28 |
| JP7799723B2 (ja) | 2026-01-15 |
| CN107406835A (zh) | 2017-11-28 |
| WO2016118642A8 (en) | 2016-09-15 |
| WO2016118642A1 (en) | 2016-07-28 |
| US20240309053A1 (en) | 2024-09-19 |
| US12018051B2 (en) | 2024-06-25 |
| US20230287055A1 (en) | 2023-09-14 |
| EP3247388A1 (en) | 2017-11-29 |
| RS67526B1 (sr) | 2026-01-30 |
| US10654898B2 (en) | 2020-05-19 |
| EP3247388B1 (en) | 2025-09-10 |
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