PL323148A1 - Esters of crabapenemes - Google Patents

Esters of crabapenemes

Info

Publication number
PL323148A1
PL323148A1 PL96323148A PL32314896A PL323148A1 PL 323148 A1 PL323148 A1 PL 323148A1 PL 96323148 A PL96323148 A PL 96323148A PL 32314896 A PL32314896 A PL 32314896A PL 323148 A1 PL323148 A1 PL 323148A1
Authority
PL
Poland
Prior art keywords
crabapenemes
esters
Prior art date
Application number
PL96323148A
Other languages
English (en)
Inventor
George Burton
Stephen Frederick Moss
Alfred John Eglington
Stephen Christopher Marti Fell
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9508960.3A external-priority patent/GB9508960D0/en
Priority claimed from GBGB9508959.5A external-priority patent/GB9508959D0/en
Priority claimed from GBGB9508964.5A external-priority patent/GB9508964D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of PL323148A1 publication Critical patent/PL323148A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D477/08—Modification of a carboxyl group directly attached in position 2, e.g. esterification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL96323148A 1995-05-03 1996-05-02 Esters of crabapenemes PL323148A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9508960.3A GB9508960D0 (en) 1995-05-03 1995-05-03 Novel compounds
GBGB9508959.5A GB9508959D0 (en) 1995-05-03 1995-05-03 Novel compounds
GBGB9508964.5A GB9508964D0 (en) 1995-05-03 1995-05-03 Novel compounds
PCT/EP1996/001882 WO1996034869A1 (en) 1995-05-03 1996-05-02 Esters of carbapenems

Publications (1)

Publication Number Publication Date
PL323148A1 true PL323148A1 (en) 1998-03-16

Family

ID=27267697

Family Applications (1)

Application Number Title Priority Date Filing Date
PL96323148A PL323148A1 (en) 1995-05-03 1996-05-02 Esters of crabapenemes

Country Status (14)

Country Link
EP (1) EP0823911A1 (cs)
JP (1) JPH11504912A (cs)
KR (1) KR19990008354A (cs)
CN (1) CN1184480A (cs)
AU (1) AU5814196A (cs)
BR (1) BR9608318A (cs)
CA (1) CA2217885A1 (cs)
CZ (1) CZ347697A3 (cs)
HU (1) HUP9801061A3 (cs)
MX (1) MX9708422A (cs)
NO (1) NO974995L (cs)
PL (1) PL323148A1 (cs)
TR (1) TR199701289T2 (cs)
WO (1) WO1996034869A1 (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100771019B1 (ko) * 2002-03-20 2007-10-29 주식회사 만도 브레이크 액압제어장치
GB0400329D0 (en) * 2004-01-08 2004-02-11 Glaxo Group Ltd Novel processes
GB0400405D0 (en) * 2004-01-09 2004-02-11 Glaxo Group Ltd Novel processes
JP2007039383A (ja) * 2005-08-03 2007-02-15 Dainippon Sumitomo Pharma Co Ltd アリールカルバペネム化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
DK637888A (da) * 1987-11-24 1989-05-25 Hoffmann La Roche Carboxylsyreestere
GB8809534D0 (en) * 1988-04-22 1988-05-25 Beecham Group Plc Novel compounds
ES2188621T3 (es) * 1993-10-29 2003-07-01 Smithkline Beecham Plc Derivados de 2-(pirazol-3-il)carbapenem.

Also Published As

Publication number Publication date
TR199701289T2 (xx) 1998-08-21
BR9608318A (pt) 1999-01-26
AU5814196A (en) 1996-11-21
WO1996034869A1 (en) 1996-11-07
HUP9801061A2 (hu) 1998-08-28
NO974995D0 (no) 1997-10-30
HUP9801061A3 (en) 1999-01-28
CA2217885A1 (en) 1996-11-07
NO974995L (no) 1997-10-30
MX9708422A (es) 1998-02-28
JPH11504912A (ja) 1999-05-11
CN1184480A (zh) 1998-06-10
CZ347697A3 (cs) 1998-06-17
EP0823911A1 (en) 1998-02-18
KR19990008354A (ko) 1999-01-25

Similar Documents

Publication Publication Date Title
SG49973A1 (en) Ester synthesis
PL322277A1 (en) Derivatives of pyrazol-4-ylobenzoyl
PL327569A1 (en) Promedications of thrombosin inhibitors
GB9526560D0 (en) Use of 2-Amino-Heterocycles
PL324451A1 (en) Derivatives of diphenylmethylenepiperidine
GB9722733D0 (en) Production of esters
HUP9601524A2 (en) Prodrugs of paclytaxel-derivatives
IL116924A (en) Preparation of n-aryl - and n-hetarylhydroxylamines
ZA96725B (en) Use of phenyclyclohexylcarboxamides
PL320114A1 (en) Phenyl-substituted fluoroderivatives of 4-azasteroides
PL323141A1 (en) Esters of crabapenemes
AU7290096A (en) Substituted benzylidenecyanoacetic esters
IL117786A (en) Preparation of alpha-bisoximes
ZA971235B (en) Novel esters of 3-hydroxy-piperidinemethanol derivatives
GB9501619D0 (en) Preparation of esters
GB9500685D0 (en) Preparation of esters
ZA964267B (en) Preparation of alkylthiopropionic pentarythritol esters
GB9726247D0 (en) Preparation of esters
GB9726246D0 (en) Preparation of esters
GB9504913D0 (en) Production of trialkoxypropane
GB9525077D0 (en) Esters
GB9525417D0 (en) Esters
GB9525144D0 (en) Purification of esters
ZA962440B (en) Destressing of railtracks
SG64924A1 (en) Inhibiting photodecompostion of 3-substituted-2- oxindoles