PL3116897T3 - Pochodne polimyksyny i ich zastosowanie w terapii skojarzonej razem z różnymi antybiotykami - Google Patents

Pochodne polimyksyny i ich zastosowanie w terapii skojarzonej razem z różnymi antybiotykami

Info

Publication number
PL3116897T3
PL3116897T3 PL15715172T PL15715172T PL3116897T3 PL 3116897 T3 PL3116897 T3 PL 3116897T3 PL 15715172 T PL15715172 T PL 15715172T PL 15715172 T PL15715172 T PL 15715172T PL 3116897 T3 PL3116897 T3 PL 3116897T3
Authority
PL
Poland
Prior art keywords
combination therapy
different antibiotics
therapy together
polymyxin derivatives
polymyxin
Prior art date
Application number
PL15715172T
Other languages
English (en)
Polish (pl)
Inventor
Pamela Brown
Michael Dawson
Mona SIMONOVIC
Steven Boakes
Esther DUPERCHY
Steven James Stanway
Antoinette Wilson
Stephen Frederick Moss
Original Assignee
Spero Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201404301A external-priority patent/GB201404301D0/en
Priority claimed from GB201421019A external-priority patent/GB201421019D0/en
Application filed by Spero Therapeutics, Inc. filed Critical Spero Therapeutics, Inc.
Publication of PL3116897T3 publication Critical patent/PL3116897T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL15715172T 2014-03-11 2015-03-11 Pochodne polimyksyny i ich zastosowanie w terapii skojarzonej razem z różnymi antybiotykami PL3116897T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB201404301A GB201404301D0 (en) 2014-03-11 2014-03-11 Compounds and combinations
GB201421019A GB201421019D0 (en) 2014-11-26 2014-11-26 Compounds
EP15715172.1A EP3116897B1 (en) 2014-03-11 2015-03-11 Polymyxin derivatives and their use in combination therapy together with different antibiotics
PCT/EP2015/055046 WO2015135976A1 (en) 2014-03-11 2015-03-11 Polymyxin derivatives and their use in combination therapy together with different antibiotics

Publications (1)

Publication Number Publication Date
PL3116897T3 true PL3116897T3 (pl) 2022-05-30

Family

ID=52823596

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15715172T PL3116897T3 (pl) 2014-03-11 2015-03-11 Pochodne polimyksyny i ich zastosowanie w terapii skojarzonej razem z różnymi antybiotykami

Country Status (21)

Country Link
US (3) US20170073373A1 (OSRAM)
EP (1) EP3116897B1 (OSRAM)
JP (1) JP6785659B2 (OSRAM)
KR (2) KR20230152779A (OSRAM)
CN (1) CN106232617B (OSRAM)
AU (1) AU2015228898B2 (OSRAM)
CA (1) CA2940455C (OSRAM)
CY (1) CY1125175T1 (OSRAM)
DK (1) DK3116897T3 (OSRAM)
ES (1) ES2910072T3 (OSRAM)
HR (1) HRP20220387T1 (OSRAM)
IL (1) IL247243B (OSRAM)
LT (1) LT3116897T (OSRAM)
MX (1) MX359104B (OSRAM)
PL (1) PL3116897T3 (OSRAM)
PT (1) PT3116897T (OSRAM)
RS (1) RS63138B1 (OSRAM)
RU (1) RU2740190C2 (OSRAM)
SI (1) SI3116897T1 (OSRAM)
TW (1) TWI709575B (OSRAM)
WO (1) WO2015135976A1 (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX355217B (es) * 2011-11-18 2018-04-10 New Pharma Licence Holdings Ltd Derivados de polimixina.
WO2015149131A1 (en) 2014-04-01 2015-10-08 Monash University Polymyxin derivatives as antimicrobial compounds
EP3224273A1 (en) 2014-11-26 2017-10-04 New Pharma Licence Holdings Limited Compounds
CN107257803B (zh) 2014-12-16 2021-02-05 上海盟科药业股份有限公司 用于治疗细菌感染的多粘菌素类抗菌剂
CN105030744B (zh) * 2015-07-09 2019-04-19 广州英赛特生物技术有限公司 取代苯胍衍生物作为多粘菌素类抗生素增效剂的应用
JP7367950B2 (ja) * 2015-09-29 2023-10-24 モナッシュ ユニバーシティ 抗菌性ポリミキシン誘導体化合物
JP6744622B2 (ja) * 2016-06-16 2020-08-19 学校法人上智学院 ピペリジン化合物の製造方法
EP3704135A4 (en) * 2017-11-02 2022-04-27 The University of Queensland PEPTIDE ANTIBIOTICS
TWI851584B (zh) 2018-06-25 2024-08-11 新加坡商雲頂新耀股份有限公司 化合物
CN111690040A (zh) * 2019-03-12 2020-09-22 上海来益生物药物研究开发中心有限责任公司 多粘菌素衍生物、其制备方法和应用
CN115298198A (zh) 2020-01-21 2022-11-04 上海盟科药业股份有限公司 用于肾相关癌症靶向治疗的新型化合物和组合物
WO2022098950A1 (en) 2020-11-06 2022-05-12 Spero Therapeutics, Inc. Compounds
CN120699105B (zh) * 2025-08-19 2025-11-21 中国药科大学 一种氘代抗菌肽及其组合物和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
BRPI0715095B8 (pt) * 2006-08-11 2021-05-25 Northern Antibiotics Oy derivado de polimixina da fórmula geral (i); produto de combinação; composição farmacêutica; método para se sensibilizar bactérias gram-negativas a um agente antibacteriano; método para o desenvolvimento de antibióticos; método para a redução da toxicidade de polimixinas, octapeptinas naturais e seus derivados durante a aplicação das mesmas no tratamento de infecções em um indivíduo; método para melhorar as propriedades farmacocinéticas, de polimixinas, octapeptinas naturais e seus derivados; método para a sensibilização de bactérias gram-negativas clinicamente importantes a um complemento de mecanismo de defesa presente no soro; uso de um derivado; e processo para a preparação de um derivado de polimixina da fórmula (i).
NZ593892A (en) * 2008-12-23 2013-11-29 Biosource Pharm Inc Antibiotic compositions for the treatment of gram negative infections
CN101851270A (zh) * 2009-04-03 2010-10-06 梁浩 一种多粘菌素衍生物及其制备方法
US8415307B1 (en) * 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012168820A1 (en) * 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
MX355217B (es) * 2011-11-18 2018-04-10 New Pharma Licence Holdings Ltd Derivados de polimixina.
RU2730012C2 (ru) * 2013-05-22 2020-08-14 Сперо Терапьютикс, Инк. Производные полимиксина и их применение в комбинированной терапии совместно с различными антибиотиками

Also Published As

Publication number Publication date
AU2015228898B2 (en) 2018-11-15
IL247243B (en) 2020-04-30
RU2016139978A (ru) 2018-04-13
KR20160135739A (ko) 2016-11-28
MX359104B (es) 2018-09-14
CN106232617B (zh) 2022-06-24
EP3116897A1 (en) 2017-01-18
DK3116897T3 (da) 2022-03-28
JP6785659B2 (ja) 2020-11-18
IL247243A0 (en) 2016-09-29
US20210221848A1 (en) 2021-07-22
US20230322858A1 (en) 2023-10-12
WO2015135976A1 (en) 2015-09-17
SI3116897T1 (sl) 2022-06-30
MX2016011682A (es) 2017-04-27
CA2940455C (en) 2023-03-21
EP3116897B1 (en) 2022-03-02
RU2740190C2 (ru) 2021-01-12
US20170073373A1 (en) 2017-03-16
ES2910072T3 (es) 2022-05-11
KR20230152779A (ko) 2023-11-03
HRP20220387T1 (hr) 2022-05-27
RU2016139978A3 (OSRAM) 2018-10-17
TW201617362A (zh) 2016-05-16
CA2940455A1 (en) 2015-09-17
TWI709575B (zh) 2020-11-11
LT3116897T (lt) 2022-05-10
CN106232617A (zh) 2016-12-14
JP2017510570A (ja) 2017-04-13
AU2015228898A1 (en) 2016-10-20
RS63138B1 (sr) 2022-05-31
PT3116897T (pt) 2022-04-07
CY1125175T1 (el) 2024-12-13

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