PL3065759T3 - Środki immunosupresyjne i ich zastosowanie w leczeniu - Google Patents

Środki immunosupresyjne i ich zastosowanie w leczeniu

Info

Publication number
PL3065759T3
PL3065759T3 PL14793594T PL14793594T PL3065759T3 PL 3065759 T3 PL3065759 T3 PL 3065759T3 PL 14793594 T PL14793594 T PL 14793594T PL 14793594 T PL14793594 T PL 14793594T PL 3065759 T3 PL3065759 T3 PL 3065759T3
Authority
PL
Poland
Prior art keywords
therapy
immunosuppressive agents
immunosuppressive
agents
Prior art date
Application number
PL14793594T
Other languages
English (en)
Inventor
Marit Otterlei
Original Assignee
Norwegian University Of Science And Technology (Ntnu)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwegian University Of Science And Technology (Ntnu) filed Critical Norwegian University Of Science And Technology (Ntnu)
Publication of PL3065759T3 publication Critical patent/PL3065759T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL14793594T 2013-11-06 2014-11-06 Środki immunosupresyjne i ich zastosowanie w leczeniu PL3065759T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1319620.9A GB201319620D0 (en) 2013-11-06 2013-11-06 Immunosuppressive agents and their use in therapy
PCT/EP2014/073966 WO2015067712A1 (en) 2013-11-06 2014-11-06 Immunosuppressive agents and their use in therapy
EP14793594.4A EP3065759B1 (en) 2013-11-06 2014-11-06 Immunosuppressive agents and their use in therapy

Publications (1)

Publication Number Publication Date
PL3065759T3 true PL3065759T3 (pl) 2021-10-25

Family

ID=49767770

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14793594T PL3065759T3 (pl) 2013-11-06 2014-11-06 Środki immunosupresyjne i ich zastosowanie w leczeniu

Country Status (11)

Country Link
US (2) US10517923B2 (pl)
EP (1) EP3065759B1 (pl)
DK (1) DK3065759T3 (pl)
ES (1) ES2869901T3 (pl)
GB (1) GB201319620D0 (pl)
HR (1) HRP20210792T1 (pl)
LT (1) LT3065759T (pl)
PL (1) PL3065759T3 (pl)
PT (1) PT3065759T (pl)
RS (1) RS62047B1 (pl)
WO (1) WO2015067712A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201319621D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy
GB201319620D0 (en) * 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy
GB201507722D0 (en) 2015-05-06 2015-06-17 Norwegian Univ Sci & Tech Ntnu Anti-bacterial agents and their use in therapy
GB201507721D0 (en) * 2015-05-06 2015-06-17 Norwegian Univ Sci & Tech Ntnu Immunosuppressive agents and their use in therapy
CA3018561A1 (en) * 2016-03-21 2017-09-28 Rhode Island Council On Postsecondary Education Ph-sensitive peptides
EP3573637A4 (en) * 2017-01-27 2020-11-11 Vanderbilt University NUCLEAR FUS TRANSLOCATION INHIBITORS FOR THE TREATMENT OF FIBROSIS
WO2020138674A1 (ko) * 2018-12-26 2020-07-02 (주)케어젠 근육 이완용 조성물
MX2020014330A (es) * 2018-12-26 2021-03-09 Caregen Co Ltd Composicion para relajacion muscular.
KR102483938B1 (ko) * 2020-06-12 2023-01-04 (주)케어젠 펜타펩타이드를 유효성분으로 포함하는 항알러지 또는 아토피피부염 개선용 조성물
EP4166155A4 (en) * 2020-06-12 2023-05-17 Caregen Co., Ltd. COMPOSITION COMPRISING A PENTAPEPTIDE AS ACTIVE PRINCIPLE
KR102463320B1 (ko) * 2020-06-12 2022-11-07 (주)케어젠 펜타펩타이드를 유효성분으로 포함하는 통증의 완화, 예방 또는 치료용 조성물
KR102469721B1 (ko) * 2020-06-12 2022-11-23 (주)케어젠 보툴리눔 톡신 유사 활성을 갖는 펩타이드 및 이의 용도
KR102570768B1 (ko) * 2020-06-12 2023-08-28 (주)케어젠 펜타펩타이드를 유효성분으로 포함하는 다한증 치료용 조성물
KR102456989B1 (ko) * 2020-06-12 2022-10-21 (주)케어젠 항비만 활성을 가지는 디옥시콜산-펩타이드 결합체 및 이의 용도
US11741686B2 (en) 2020-12-01 2023-08-29 Raytheon Company System and method for processing facility image data

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198541A (en) 1987-08-11 1993-03-30 New York University Dna encoding bactericidal/permeability-increasing proteins
US6316003B1 (en) * 1989-12-21 2001-11-13 Whitehead Institute For Biomedical Research Tat-derived transport polypeptides
US5643578A (en) 1992-03-23 1997-07-01 University Of Massachusetts Medical Center Immunization by inoculation of DNA transcription unit
DK0642579T3 (da) 1992-05-19 1999-10-18 Xoma Corp Forbedrede fremgangsmåder til fremstilling af endotoxin-bindende proteiner
US5420019A (en) 1993-02-02 1995-05-30 Xoma Corporation Stable bactericidal/permeability-increasing protein muteins
NZ263057A (en) 1993-03-12 2000-12-22 Xoma Corp Use of bactericidal permeability increasing proteins or derivative for treating chronic inflammatory diseases, neutralising heparin, inhibiting angiogenesis, tumour and epithelial cell proliferation
NZ263344A (en) 1993-03-12 1997-08-22 Xoma Corp Human bactericidal/permeability increasing (bpi) protein functional domain peptides and their use
CA2173611C (en) 1993-10-05 2005-07-26 Paul A. M. Van Leeuwen Method of treating depressed reticuloendothelial system function
ES2179095T3 (es) 1994-01-14 2003-01-16 Xoma Technology Ltd Metodos y materiales anti bacterias gram positivas.
CN1112933C (zh) 1994-01-14 2003-07-02 爱克索马技术有限公司 抗真菌的方法和物质
US5643875A (en) 1994-01-24 1997-07-01 Friedmann; Nadav Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products
US5447913A (en) 1994-03-11 1995-09-05 Xoma Corporation Therapeutic uses of bactericidal/permeability-increasing protein dimer products
US5578568A (en) 1994-04-22 1996-11-26 Xoma Corporation Method of treating conditions associated with intestinal ischemia/reperfusion
US5646114A (en) 1994-07-11 1997-07-08 Xoma Corporation Anti-protozoan methods
JPH10508576A (ja) 1994-09-15 1998-08-25 ゾーマ コーポレイション 抗真菌性ペプチド
US5912228A (en) 1995-01-13 1999-06-15 Xoma Corporation Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products
US5494896A (en) 1995-03-31 1996-02-27 Xoma Corporation Method of treating conditions associated with burn injuries
US6057291A (en) * 1995-06-02 2000-05-02 University Of British Columbia Antimicrobial cationic peptides
EP0839156A1 (en) 1995-07-20 1998-05-06 Xoma Corporation Anti-fungal peptides
US5686414A (en) 1995-11-14 1997-11-11 Xoma Corporation Methods of treating conditions associated with corneal transplantation
US5851802A (en) 1996-03-22 1998-12-22 Xoma Corporation Methods for recombinant microbial production of fusion proteins and BPI-derived peptides
US5741779A (en) 1996-05-10 1998-04-21 Xoma Corporation Antithrombotic materials and methods
ATE198050T1 (de) 1996-05-10 2000-12-15 Xoma Technology Ltd Therapeutische anwendungen von bpi-protein- produkten zur behandlung von humaner meningococcämia
JP2000511190A (ja) 1996-05-23 2000-08-29 ゾーマ コーポレイション 外傷に起因する出血に見舞われたヒトにおけるbpiタンパク質産物の治療用途
US5888973A (en) 1996-08-09 1999-03-30 Xoma Corporation Anti-chlamydial uses of BPI protein products
US6482796B2 (en) 1996-11-01 2002-11-19 Xoma Corporation Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients
NZ335401A (en) 1996-11-01 2000-12-22 Xoma Corp Therapeutic uses of BPI protein products in cystic fibrosis patients
US6093573A (en) 1997-06-20 2000-07-25 Xoma Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)
US6013631A (en) 1998-06-19 2000-01-11 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) deletion analogs
SE512161C2 (sv) 1998-06-30 2000-02-07 Sandvik Ab Hårdmetall och användning av denna vid olje- och gasutvinning
WO2000018798A1 (en) 1998-09-25 2000-04-06 Xoma Technology Ltd. Antifungal and antibacterial peptide
AU778001B2 (en) 1999-01-22 2004-11-11 Board Of Regents, The University Of Texas System Method of treating chronic cardiac disease
US6153584A (en) 1999-04-01 2000-11-28 Levy; Ofer Therapeutic uses of BPI protein products in BPI-deficient humans
US6355616B1 (en) 1999-06-25 2002-03-12 Xoma (Us) Technology Ltd. Derivative compounds derived from or based on bactericidal/permeability-increasing protein
WO2001004348A1 (en) 1999-07-12 2001-01-18 Xoma Technology Ltd. Methods to identify inhibitors of f1/f0 atpase
AU4204200A (en) 1999-07-12 2001-01-30 Xoma Technology Ltd. Therapeutic uses of bpi protein products for inhibiting H+/K+ atpase activity
US6436660B1 (en) 1999-07-12 2002-08-20 Xoma Technology Ltd. Identification of novel antimicrobial agents using metabolic oxidation-reduction indicator dyes
WO2001004347A1 (en) 1999-07-12 2001-01-18 Xoma Technology Ltd. Method to identify inhibitors f1/f0 atpase
AU6513701A (en) * 2000-05-30 2001-12-11 Advanced Res & Tech Inst Compositions and methods for identifying agents which modulate pten function andpi-3 kinase pathways
US20030166528A1 (en) 2000-10-11 2003-09-04 Jong-Jye Lin Antifungal compound
WO2002055099A2 (en) 2000-12-01 2002-07-18 Xoma Technology Ltd Modulation of pericyte proliferation using bpi protein products or bpi inhibitors
EP1379265A4 (en) 2001-03-28 2005-09-14 Helix Biomedix Inc SHORT BIOACTIVE PEPTIDES AND METHODS OF USE
US7517857B2 (en) 2002-01-29 2009-04-14 Posco Immune-modulating peptide
WO2005068504A1 (ja) * 2004-01-19 2005-07-28 Medical And Biological Laboratories Co., Ltd. 炎症性サイトカイン抑制剤
AU2006244072B2 (en) * 2005-05-10 2012-09-20 Intermune, Inc. Pyridone derivatives for modulating stress-activated protein kinase system
US7612181B2 (en) * 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
US7579318B2 (en) * 2005-12-06 2009-08-25 Centre De La Recherche De La Scientifique Cell penetrating peptides for intracellular delivery of molecules
EP2084527A4 (en) * 2006-11-02 2011-07-27 Seattle Genetics Inc METHOD FOR TREATING NEOPLASIA, AUTOIMMUNE AND INFLAMMATORY DISEASES
US8419332B2 (en) * 2007-10-19 2013-04-16 Atlas Bolt & Screw Company Llc Non-dimpling fastener
GB0803352D0 (en) * 2008-02-22 2008-04-02 Ntnu Technology Transfer As Oligopeptidic compounds and uses thereof
US8722052B2 (en) * 2008-11-17 2014-05-13 The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin Vaccinia virus protein A46 peptide and use thereof
GB0916576D0 (en) * 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
AT510991A5 (de) * 2009-10-09 2015-02-15 Kemijski Inst Peptide für die Inhibition MyD88-abhängiger Signalwege
US20130059773A1 (en) 2010-02-24 2013-03-07 Veronique Witko-Sarsat Compounds for the treatment of inflammation and neutropenia
US8697627B2 (en) * 2011-05-09 2014-04-15 Eip Pharma, Llc Compositions and methods for treating alzheimer's disease
WO2012177892A2 (en) * 2011-06-21 2012-12-27 University Of Florida Research Foundation, Inc. Type i interferon mimetics as therapeutics for cancer, viral infections, and multiple sclerosis
EP2732032B1 (en) * 2011-07-12 2016-05-11 The University of British Columbia Neuroprotective peptides that inhibit interaction between palmitoyl acyl transferase zinc- finger dhhc type containing 17 (zd17) and c-jun n-terminal kinase (jnk)
US9234048B2 (en) * 2012-01-18 2016-01-12 Wisconsin Alumni Research Foundation Boronate-mediated delivery of molecules into cells
KR101497972B1 (ko) * 2012-03-21 2015-03-03 서울대학교산학협력단 Nod2 신호전달 경로를 표적으로 하는 패혈증 치료제 스크리닝 방법 및 패혈증 치료제
GB201319621D0 (en) * 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy
GB201319620D0 (en) * 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy

Also Published As

Publication number Publication date
US11246907B2 (en) 2022-02-15
HRP20210792T1 (hr) 2021-08-20
EP3065759B1 (en) 2021-03-31
US20200323953A1 (en) 2020-10-15
US20160279193A1 (en) 2016-09-29
DK3065759T3 (da) 2021-05-17
RS62047B1 (sr) 2021-07-30
ES2869901T3 (es) 2021-10-26
WO2015067712A1 (en) 2015-05-14
EP3065759A1 (en) 2016-09-14
LT3065759T (lt) 2021-08-10
GB201319620D0 (en) 2013-12-18
US10517923B2 (en) 2019-12-31
PT3065759T (pt) 2021-05-17

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