PL2999701T3 - 2-fenyloimidazo[1,2-a]pirymidyny jako środki do obrazowania - Google Patents
2-fenyloimidazo[1,2-a]pirymidyny jako środki do obrazowaniaInfo
- Publication number
- PL2999701T3 PL2999701T3 PL14724757T PL14724757T PL2999701T3 PL 2999701 T3 PL2999701 T3 PL 2999701T3 PL 14724757 T PL14724757 T PL 14724757T PL 14724757 T PL14724757 T PL 14724757T PL 2999701 T3 PL2999701 T3 PL 2999701T3
- Authority
- PL
- Poland
- Prior art keywords
- phenylimidazo
- pyrimidines
- imaging agents
- imaging
- agents
- Prior art date
Links
- ONYRUSCZUWEZDP-UHFFFAOYSA-N 2-phenylimidazo[1,2-a]pyrimidine Chemical class N1=C2N=CC=CN2C=C1C1=CC=CC=C1 ONYRUSCZUWEZDP-UHFFFAOYSA-N 0.000 title 1
- 239000012216 imaging agent Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13168830 | 2013-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2999701T3 true PL2999701T3 (pl) | 2017-09-29 |
Family
ID=48446195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14724757T PL2999701T3 (pl) | 2013-05-23 | 2014-05-19 | 2-fenyloimidazo[1,2-a]pirymidyny jako środki do obrazowania |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9801961B2 (pl) |
| EP (1) | EP2999701B1 (pl) |
| JP (1) | JP6130055B2 (pl) |
| KR (1) | KR101770494B1 (pl) |
| CN (1) | CN105229009B (pl) |
| AR (1) | AR096371A1 (pl) |
| AU (1) | AU2014270524B2 (pl) |
| BR (1) | BR112015025140A2 (pl) |
| CA (1) | CA2907605A1 (pl) |
| DK (1) | DK2999701T3 (pl) |
| ES (1) | ES2629389T3 (pl) |
| HU (1) | HUE033612T2 (pl) |
| MX (1) | MX2015015893A (pl) |
| PL (1) | PL2999701T3 (pl) |
| RU (1) | RU2665580C2 (pl) |
| SG (1) | SG11201509503QA (pl) |
| SI (1) | SI2999701T1 (pl) |
| TW (1) | TW201500360A (pl) |
| WO (1) | WO2014187762A1 (pl) |
| ZA (1) | ZA201506570B (pl) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112017021408B1 (pt) | 2015-04-08 | 2022-05-17 | Bayer Cropscience Aktiengesellschaft | Derivados de heterociclo bicíclico condensado, método para controlar pragas animais, e formulação agroquímica |
| TW201718514A (zh) | 2015-08-07 | 2017-06-01 | 拜耳作物科學股份有限公司 | 作為殺蟲劑之經２－（雜）芳基取代之稠合雜環衍生物 |
| EP3355699B1 (en) * | 2015-09-29 | 2021-03-31 | OncoTherapy Science, Inc. | Bicyclic compound and use thereof for inhibiting suv39h2 |
| RU2018119344A (ru) | 2015-10-26 | 2019-11-28 | Байер Кропсайенс Акциенгезельшафт | Конденсированные бициклические гетероциклические производные в качестве средства для борьбы с вредителями |
| WO2017093180A1 (de) | 2015-12-01 | 2017-06-08 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| CN105582168A (zh) * | 2016-01-08 | 2016-05-18 | 王明强 | 一种治疗体弱多病、元气不足、免疫力低下的中药药剂 |
| WO2017144341A1 (de) | 2016-02-23 | 2017-08-31 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| WO2017174414A1 (de) | 2016-04-05 | 2017-10-12 | Bayer Cropscience Aktiengesellschaft | Naphthalin-derivate als schädlingsbekämpfungsmittel |
| EP3241830A1 (de) | 2016-05-04 | 2017-11-08 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| KR102435080B1 (ko) | 2016-07-19 | 2022-08-22 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 해충 방제제로서의 축합 바이시클릭 헤테로사이클 유도체 |
| WO2018015546A1 (en) | 2016-07-22 | 2018-01-25 | Ac Immune S.A. | Compounds for imaging tau protein aggregates |
| IL264239B (en) | 2016-07-22 | 2022-08-01 | Ac Immune Sa | Compounds for imaging tau protein aggregates |
| MX2019001918A (es) | 2016-08-15 | 2019-09-06 | Bayer Cropscience Ag | Derivados del heterociclo biciclico condensado como agentes de control de plagas. |
| TW201825499A (zh) | 2016-09-19 | 2018-07-16 | 德商拜耳作物科學股份有限公司 | 作為殺蟲劑之稠合雙環雜環衍生物 |
| WO2018065288A1 (de) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz |
| KR102515694B1 (ko) | 2017-01-10 | 2023-03-29 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 헤테로사이클 유도체 |
| JP7098630B2 (ja) | 2017-01-10 | 2022-07-11 | バイエル・アクチエンゲゼルシヤフト | 有害生物防除剤としてのヘテロサイクレン誘導体 |
| WO2018138050A1 (de) | 2017-01-26 | 2018-08-02 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| EP3615540B1 (de) | 2017-04-24 | 2022-04-27 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| JP6831802B2 (ja) * | 2018-01-12 | 2021-02-17 | 上海富吉医療器械有限公司Ｓｈａｎｇｈａｉ Ｃｈａｒｔｗｅｌｌ Ｍｅｄｉｃａｌ Ｉｎｓｔｒｕｍｅｎｔ Ｃｏ．， Ｌｔｄ． | 放射性核種標識化合物及びこれを含有するイメージング剤 |
| EP3305786A3 (de) | 2018-01-22 | 2018-07-25 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| US20210041447A1 (en) | 2018-01-24 | 2021-02-11 | Ac Immune Sa | Azacarboline compounds for the detection of tau aggregates |
| US11306089B2 (en) | 2018-01-24 | 2022-04-19 | Life Molecular Imaging Limited | Gamma-carboline compounds for the detection of Tau aggregates |
| KR20200122353A (ko) | 2018-02-21 | 2020-10-27 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 축합 바이시클릭 헤테로시클릭 유도체 |
| SG11202012150UA (en) * | 2018-06-08 | 2021-01-28 | Ac Immune Sa | Novel compounds for diagnosis |
| MX2021010217A (es) | 2019-02-26 | 2021-09-21 | Bayer Ag | Derivados heterociclos biciclicos condensados como plaguicida. |
| CN113710669A (zh) | 2019-02-26 | 2021-11-26 | 拜耳公司 | 作为农药的稠合双环杂环衍生物 |
| CN114890955A (zh) * | 2022-06-23 | 2022-08-12 | 江西瑞威尔生物科技有限公司 | 一种n取代吗啉类有机化合物的制备工艺 |
| JP2025526423A (ja) * | 2022-07-28 | 2025-08-13 | エーシー・イミューン・エス・アー | 新規化合物 |
| TW202521543A (zh) * | 2023-11-21 | 2025-06-01 | 瑞士商諾華公司 | 取代咪唑并芳烴及其使用方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE288915T1 (de) * | 1999-11-10 | 2005-02-15 | Ortho Mcneil Pharm Inc | Substituierte 2-aryl-3-(heteroaryl)-imidazo(1,2- alpha)pyrimidine und ihren verwandten arzneimittel und verfahren |
| US6642229B2 (en) * | 2000-05-24 | 2003-11-04 | Merck Sharp & Dohme Ltd. | 3-Phenyl-imidazo-pyrimidine derivatives as ligands for GABA receptors |
| AU2006261917A1 (en) | 2005-06-24 | 2007-01-04 | The Trustees Of The University Of Pennsylvania | Radiolabeled-pegylation of ligands for use as imaging agents |
| WO2007033080A2 (en) | 2005-09-12 | 2007-03-22 | Emory University | Alzheimer's disease imaging agents |
| WO2007034282A2 (en) * | 2005-09-19 | 2007-03-29 | Pfizer Products Inc. | Diaryl-imidazole compounds condensed with a heterocycle as c3a receptor antagonists |
| US8022075B2 (en) * | 2005-11-30 | 2011-09-20 | Fujifilm Ri Pharma Co., Ltd. | Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition |
| EP2023919A4 (en) * | 2006-05-08 | 2010-12-22 | Molecular Neuroimaging Llc | COMPOUNDS AND AMYLOID PROBES FOR THERAPY AND IMAGING USES |
| RU2008150377A (ru) | 2006-05-19 | 2010-06-27 | Нихон Меди-Физикс Ко., Лтд. (Jp) | Новое соединение, обладающее сродством к амилоиду |
| US8691187B2 (en) * | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
| US8410117B2 (en) * | 2010-03-26 | 2013-04-02 | Hoffmann-La Roche Inc. | Imidazopyrimidine derivatives |
| ES2624453T3 (es) * | 2013-04-29 | 2017-07-14 | F. Hoffmann-La Roche Ag | Derivados de 2-fenil o 2-hetaril-imidazol[1,2-a]piridina |
-
2014
- 2014-05-19 EP EP14724757.1A patent/EP2999701B1/en active Active
- 2014-05-19 MX MX2015015893A patent/MX2015015893A/es unknown
- 2014-05-19 BR BR112015025140A patent/BR112015025140A2/pt not_active Application Discontinuation
- 2014-05-19 DK DK14724757.1T patent/DK2999701T3/en active
- 2014-05-19 CA CA2907605A patent/CA2907605A1/en not_active Abandoned
- 2014-05-19 SI SI201430251T patent/SI2999701T1/sl unknown
- 2014-05-19 PL PL14724757T patent/PL2999701T3/pl unknown
- 2014-05-19 HU HUE14724757A patent/HUE033612T2/en unknown
- 2014-05-19 WO PCT/EP2014/060203 patent/WO2014187762A1/en not_active Ceased
- 2014-05-19 ES ES14724757.1T patent/ES2629389T3/es active Active
- 2014-05-19 KR KR1020157033039A patent/KR101770494B1/ko not_active Expired - Fee Related
- 2014-05-19 AU AU2014270524A patent/AU2014270524B2/en not_active Ceased
- 2014-05-19 SG SG11201509503QA patent/SG11201509503QA/en unknown
- 2014-05-19 JP JP2016514351A patent/JP6130055B2/ja active Active
- 2014-05-19 RU RU2015149528A patent/RU2665580C2/ru not_active IP Right Cessation
- 2014-05-19 CN CN201480029084.XA patent/CN105229009B/zh active Active
- 2014-05-20 TW TW103117655A patent/TW201500360A/zh unknown
- 2014-05-21 AR ARP140102015A patent/AR096371A1/es unknown
-
2015
- 2015-09-07 ZA ZA2015/06570A patent/ZA201506570B/en unknown
- 2015-11-19 US US14/945,969 patent/US9801961B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN105229009B (zh) | 2017-09-29 |
| AU2014270524A8 (en) | 2015-09-24 |
| MX2015015893A (es) | 2016-03-04 |
| US20170128598A1 (en) | 2017-05-11 |
| WO2014187762A1 (en) | 2014-11-27 |
| ZA201506570B (en) | 2017-02-22 |
| AR096371A1 (es) | 2015-12-23 |
| HUE033612T2 (en) | 2017-12-28 |
| SG11201509503QA (en) | 2015-12-30 |
| TW201500360A (zh) | 2015-01-01 |
| US9801961B2 (en) | 2017-10-31 |
| KR20150144796A (ko) | 2015-12-28 |
| AU2014270524B2 (en) | 2018-01-04 |
| KR101770494B1 (ko) | 2017-08-22 |
| JP2016520091A (ja) | 2016-07-11 |
| RU2015149528A3 (pl) | 2018-03-22 |
| RU2015149528A (ru) | 2017-06-28 |
| RU2665580C2 (ru) | 2018-08-31 |
| DK2999701T3 (en) | 2017-07-10 |
| CA2907605A1 (en) | 2014-11-27 |
| ES2629389T3 (es) | 2017-08-09 |
| EP2999701A1 (en) | 2016-03-30 |
| BR112015025140A2 (pt) | 2017-07-18 |
| HK1213558A1 (zh) | 2016-07-08 |
| JP6130055B2 (ja) | 2017-05-17 |
| AU2014270524A1 (en) | 2015-09-17 |
| CN105229009A (zh) | 2016-01-06 |
| SI2999701T1 (sl) | 2017-08-31 |
| EP2999701B1 (en) | 2017-04-12 |
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