PL2999701T3 - 2-fenyloimidazo[1,2-a]pirymidyny jako środki do obrazowania - Google Patents
2-fenyloimidazo[1,2-a]pirymidyny jako środki do obrazowaniaInfo
- Publication number
- PL2999701T3 PL2999701T3 PL14724757T PL14724757T PL2999701T3 PL 2999701 T3 PL2999701 T3 PL 2999701T3 PL 14724757 T PL14724757 T PL 14724757T PL 14724757 T PL14724757 T PL 14724757T PL 2999701 T3 PL2999701 T3 PL 2999701T3
- Authority
- PL
- Poland
- Prior art keywords
- phenylimidazo
- pyrimidines
- imaging agents
- imaging
- agents
- Prior art date
Links
- ONYRUSCZUWEZDP-UHFFFAOYSA-N 2-phenylimidazo[1,2-a]pyrimidine Chemical class N1=C2N=CC=CN2C=C1C1=CC=CC=C1 ONYRUSCZUWEZDP-UHFFFAOYSA-N 0.000 title 1
- 239000012216 imaging agent Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13168830 | 2013-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2999701T3 true PL2999701T3 (pl) | 2017-09-29 |
Family
ID=48446195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14724757T PL2999701T3 (pl) | 2013-05-23 | 2014-05-19 | 2-fenyloimidazo[1,2-a]pirymidyny jako środki do obrazowania |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9801961B2 (pl) |
| EP (1) | EP2999701B1 (pl) |
| JP (1) | JP6130055B2 (pl) |
| KR (1) | KR101770494B1 (pl) |
| CN (1) | CN105229009B (pl) |
| AR (1) | AR096371A1 (pl) |
| AU (1) | AU2014270524B2 (pl) |
| BR (1) | BR112015025140A2 (pl) |
| CA (1) | CA2907605A1 (pl) |
| DK (1) | DK2999701T3 (pl) |
| ES (1) | ES2629389T3 (pl) |
| HU (1) | HUE033612T2 (pl) |
| MX (1) | MX2015015893A (pl) |
| PL (1) | PL2999701T3 (pl) |
| RU (1) | RU2665580C2 (pl) |
| SG (1) | SG11201509503QA (pl) |
| SI (1) | SI2999701T1 (pl) |
| TW (1) | TW201500360A (pl) |
| WO (1) | WO2014187762A1 (pl) |
| ZA (1) | ZA201506570B (pl) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112017021408B1 (pt) | 2015-04-08 | 2022-05-17 | Bayer Cropscience Aktiengesellschaft | Derivados de heterociclo bicíclico condensado, método para controlar pragas animais, e formulação agroquímica |
| CN108137548A (zh) | 2015-08-07 | 2018-06-08 | 拜耳作物科学股份公司 | 作为农药的2-(杂)芳基取代的稠合杂环衍生物 |
| BR112018006005A2 (pt) * | 2015-09-29 | 2018-10-30 | Oncotherapy Science Inc | composto bicíclico e uso do mesmo para inibição de suv39h2 |
| US10550116B2 (en) | 2015-10-26 | 2020-02-04 | Bayer Cropscience Aktiengesellschaft | Fused bicyclic heterocycle derivatives as pesticides |
| WO2017093180A1 (de) | 2015-12-01 | 2017-06-08 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| CN105582168A (zh) * | 2016-01-08 | 2016-05-18 | 王明强 | 一种治疗体弱多病、元气不足、免疫力低下的中药药剂 |
| WO2017144341A1 (de) | 2016-02-23 | 2017-08-31 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| WO2017174414A1 (de) | 2016-04-05 | 2017-10-12 | Bayer Cropscience Aktiengesellschaft | Naphthalin-derivate als schädlingsbekämpfungsmittel |
| EP3241830A1 (de) | 2016-05-04 | 2017-11-08 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| MX2019000793A (es) | 2016-07-19 | 2019-06-20 | Bayer Cropscience Ag | Derivados de heterociclos biciclicos condensados como pesticidas. |
| IL264239B (en) | 2016-07-22 | 2022-08-01 | Ac Immune Sa | Compounds for imaging tau protein aggregates |
| JP7059270B2 (ja) | 2016-07-22 | 2022-04-25 | エーシー・イミューン・エス・アー | タウタンパク質凝集体を画像化するための化合物 |
| EP3497102B1 (de) | 2016-08-15 | 2022-12-07 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| EP3515921B1 (de) | 2016-09-19 | 2021-10-27 | Bayer CropScience Aktiengesellschaft | Pyrazolo[1,5-a]pyridin- derivative und ihre verwendung als schädlingsbekämpfungsmittel |
| WO2018065288A1 (de) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz |
| AU2018208422B2 (en) | 2017-01-10 | 2021-11-11 | Bayer Aktiengesellschaft | Heterocyclene derivatives as pest control agents |
| UY37556A (es) | 2017-01-10 | 2018-07-31 | Bayer Ag | Derivados heterocíclicos como pesticidas |
| WO2018138050A1 (de) | 2017-01-26 | 2018-08-02 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| US20200128830A1 (en) | 2017-04-24 | 2020-04-30 | Bayer Aktiengesellschaft | Fused bicyclic heterocycle derivatives as pesticides |
| JP6831802B2 (ja) * | 2018-01-12 | 2021-02-17 | 上海富吉医療器械有限公司Ｓｈａｎｇｈａｉ Ｃｈａｒｔｗｅｌｌ Ｍｅｄｉｃａｌ Ｉｎｓｔｒｕｍｅｎｔ Ｃｏ．， Ｌｔｄ． | 放射性核種標識化合物及びこれを含有するイメージング剤 |
| EP3305786A3 (de) | 2018-01-22 | 2018-07-25 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| EP3743426A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Azacarboline compounds for the detection of tau aggregates |
| EP3743423A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Gamma-carboline compounds for the detection of tau aggregates |
| CN111741958A (zh) | 2018-02-21 | 2020-10-02 | 拜耳公司 | 作为害虫防治剂的稠合双环杂环衍生物 |
| ES2988770T3 (es) * | 2018-06-08 | 2024-11-21 | Ac Immune Sa | Nuevos compuestos para diagnóstico |
| CN113710669A (zh) | 2019-02-26 | 2021-11-26 | 拜耳公司 | 作为农药的稠合双环杂环衍生物 |
| JP7535532B2 (ja) | 2019-02-26 | 2024-08-16 | バイエル・アクチエンゲゼルシヤフト | 有害生物防除剤としての縮合二環式複素環式誘導体 |
| CN114890955A (zh) * | 2022-06-23 | 2022-08-12 | 江西瑞威尔生物科技有限公司 | 一种n取代吗啉类有机化合物的制备工艺 |
| CA3261365A1 (en) * | 2022-07-28 | 2024-02-01 | Ac Immune Sa | NEW COMPOUNDS |
| AR134414A1 (es) * | 2023-11-21 | 2026-01-14 | Novartis Ag | Imidazoarenos sustituidos y métodos para su uso |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2264403C2 (ru) * | 1999-11-10 | 2005-11-20 | Орто-Макнейл Фармасьютикал, Инк. | Замещенные 2-арил-3-(гетероарил) имидазо [1,2-а] пиримидины, содержащие их фармацевтические композиции и связанные с ними способы |
| EP1294723A1 (en) * | 2000-05-24 | 2003-03-26 | MERCK SHARP & DOHME LTD. | 3-phenyl-imidazo-pyrimidine derivatives as ligands for gaba receptors |
| US20070031328A1 (en) | 2005-06-24 | 2007-02-08 | Kung Hank F | Radiolabeled-pegylation of ligands for use as imaging agents |
| WO2007033080A2 (en) | 2005-09-12 | 2007-03-22 | Emory University | Alzheimer's disease imaging agents |
| WO2007034282A2 (en) * | 2005-09-19 | 2007-03-29 | Pfizer Products Inc. | Diaryl-imidazole compounds condensed with a heterocycle as c3a receptor antagonists |
| EP1956013B1 (en) * | 2005-11-30 | 2016-04-13 | Fujifilm RI Pharma Co., Ltd. | Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition |
| US7700616B2 (en) * | 2006-05-08 | 2010-04-20 | Molecular Neuroimaging, Llc. | Compounds and amyloid probes thereof for therapeutic and imaging uses |
| RU2008150377A (ru) | 2006-05-19 | 2010-06-27 | Нихон Меди-Физикс Ко., Лтд. (Jp) | Новое соединение, обладающее сродством к амилоиду |
| US8691187B2 (en) * | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
| US8410117B2 (en) * | 2010-03-26 | 2013-04-02 | Hoffmann-La Roche Inc. | Imidazopyrimidine derivatives |
| JP6212628B2 (ja) * | 2013-04-29 | 2017-10-11 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ２−フェニル又は２−ヘタリールイミダゾール［１，２−ａ］ピリジン誘導体 |
-
2014
- 2014-05-19 SG SG11201509503QA patent/SG11201509503QA/en unknown
- 2014-05-19 HU HUE14724757A patent/HUE033612T2/en unknown
- 2014-05-19 ES ES14724757.1T patent/ES2629389T3/es active Active
- 2014-05-19 CA CA2907605A patent/CA2907605A1/en not_active Abandoned
- 2014-05-19 EP EP14724757.1A patent/EP2999701B1/en active Active
- 2014-05-19 AU AU2014270524A patent/AU2014270524B2/en not_active Ceased
- 2014-05-19 JP JP2016514351A patent/JP6130055B2/ja active Active
- 2014-05-19 RU RU2015149528A patent/RU2665580C2/ru not_active IP Right Cessation
- 2014-05-19 BR BR112015025140A patent/BR112015025140A2/pt not_active Application Discontinuation
- 2014-05-19 CN CN201480029084.XA patent/CN105229009B/zh active Active
- 2014-05-19 SI SI201430251T patent/SI2999701T1/sl unknown
- 2014-05-19 WO PCT/EP2014/060203 patent/WO2014187762A1/en not_active Ceased
- 2014-05-19 KR KR1020157033039A patent/KR101770494B1/ko not_active Expired - Fee Related
- 2014-05-19 MX MX2015015893A patent/MX2015015893A/es unknown
- 2014-05-19 DK DK14724757.1T patent/DK2999701T3/en active
- 2014-05-19 PL PL14724757T patent/PL2999701T3/pl unknown
- 2014-05-20 TW TW103117655A patent/TW201500360A/zh unknown
- 2014-05-21 AR ARP140102015A patent/AR096371A1/es unknown
-
2015
- 2015-09-07 ZA ZA2015/06570A patent/ZA201506570B/en unknown
- 2015-11-19 US US14/945,969 patent/US9801961B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| TW201500360A (zh) | 2015-01-01 |
| KR20150144796A (ko) | 2015-12-28 |
| SG11201509503QA (en) | 2015-12-30 |
| RU2665580C2 (ru) | 2018-08-31 |
| US20170128598A1 (en) | 2017-05-11 |
| ES2629389T3 (es) | 2017-08-09 |
| CA2907605A1 (en) | 2014-11-27 |
| BR112015025140A2 (pt) | 2017-07-18 |
| KR101770494B1 (ko) | 2017-08-22 |
| JP2016520091A (ja) | 2016-07-11 |
| AU2014270524A8 (en) | 2015-09-24 |
| AR096371A1 (es) | 2015-12-23 |
| AU2014270524B2 (en) | 2018-01-04 |
| US9801961B2 (en) | 2017-10-31 |
| RU2015149528A3 (pl) | 2018-03-22 |
| RU2015149528A (ru) | 2017-06-28 |
| DK2999701T3 (en) | 2017-07-10 |
| WO2014187762A1 (en) | 2014-11-27 |
| EP2999701B1 (en) | 2017-04-12 |
| SI2999701T1 (sl) | 2017-08-31 |
| AU2014270524A1 (en) | 2015-09-17 |
| CN105229009A (zh) | 2016-01-06 |
| CN105229009B (zh) | 2017-09-29 |
| JP6130055B2 (ja) | 2017-05-17 |
| ZA201506570B (en) | 2017-02-22 |
| MX2015015893A (es) | 2016-03-04 |
| HK1213558A1 (zh) | 2016-07-08 |
| HUE033612T2 (en) | 2017-12-28 |
| EP2999701A1 (en) | 2016-03-30 |
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