PL2943493T3 - Związki terapeutyczne do leczenia zakażeń wirusowych - Google Patents
Związki terapeutyczne do leczenia zakażeń wirusowychInfo
- Publication number
- PL2943493T3 PL2943493T3 PL14701647T PL14701647T PL2943493T3 PL 2943493 T3 PL2943493 T3 PL 2943493T3 PL 14701647 T PL14701647 T PL 14701647T PL 14701647 T PL14701647 T PL 14701647T PL 2943493 T3 PL2943493 T3 PL 2943493T3
- Authority
- PL
- Poland
- Prior art keywords
- treatment
- viral infections
- therapeutic compounds
- therapeutic
- compounds
- Prior art date
Links
- 208000036142 Viral infection Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361750759P | 2013-01-09 | 2013-01-09 | |
| PCT/US2014/010937 WO2014110296A1 (en) | 2013-01-09 | 2014-01-09 | Therapeutic compounds for the treatment of viral infections |
| EP14701647.1A EP2943493B1 (en) | 2013-01-09 | 2014-01-09 | Therapeutic compounds for the treatment of viral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2943493T3 true PL2943493T3 (pl) | 2017-12-29 |
Family
ID=50023885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14701647T PL2943493T3 (pl) | 2013-01-09 | 2014-01-09 | Związki terapeutyczne do leczenia zakażeń wirusowych |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9012441B2 (pl) |
| EP (1) | EP2943493B1 (pl) |
| JP (1) | JP5860197B1 (pl) |
| AU (1) | AU2014205315B2 (pl) |
| CA (1) | CA2897268C (pl) |
| ES (1) | ES2642265T3 (pl) |
| NZ (2) | NZ631726A (pl) |
| PL (1) | PL2943493T3 (pl) |
| PT (1) | PT2943493T (pl) |
| SI (1) | SI2943493T1 (pl) |
| WO (1) | WO2014110296A1 (pl) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2553449T3 (es) | 2011-07-06 | 2015-12-09 | Gilead Sciences, Inc. | Compuestos para el tratamiento de VIH |
| CA2896244C (en) | 2013-01-09 | 2017-07-04 | Gilead Sciences, Inc. | 5-membered heteroaryls and their use as antiviral agents |
| TW201443037A (zh) | 2013-01-09 | 2014-11-16 | Gilead Sciences Inc | 治療用化合物 |
| TWI694071B (zh) | 2013-03-01 | 2020-05-21 | 美商基利科學股份有限公司 | 治療反轉錄病毒科(Retroviridae)病毒感染之治療性化合物 |
| US10202353B2 (en) | 2014-02-28 | 2019-02-12 | Gilead Sciences, Inc. | Therapeutic compounds |
| US9873680B2 (en) | 2014-08-29 | 2018-01-23 | Gilead Sciences, Inc. | Therapeutic compounds |
| IL296496B2 (en) | 2014-12-26 | 2024-10-01 | Univ Emory | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
| TW202138365A (zh) | 2016-08-19 | 2021-10-16 | 美商基利科學股份有限公司 | 治療性化合物 |
| TW201906834A (zh) | 2017-05-02 | 2019-02-16 | 英商Viiv醫療保健英國(No.5)有限公司 | 人類免疫不全病毒複製之抑制劑 |
| AR112412A1 (es) | 2017-08-17 | 2019-10-23 | Gilead Sciences Inc | Formas de sal de colina de un inhibidor de la cápside del vih |
| TWI687415B (zh) | 2017-08-17 | 2020-03-11 | 美商基利科學股份有限公司 | Hiv蛋白質膜抑制劑之固體形式 |
| KR102626210B1 (ko) | 2017-12-07 | 2024-01-18 | 에모리 유니버시티 | N4-하이드록시사이티딘 및 유도체 및 이와 관련된 항-바이러스 용도 |
| CN111836805B (zh) | 2018-02-15 | 2023-07-14 | 吉利德科学公司 | 吡啶衍生物及其用于治疗hiv感染的用途 |
| TWI745652B (zh) | 2018-02-16 | 2021-11-11 | 美商基利科學股份有限公司 | 用於製備有療效化合物之方法及中間物 |
| EP3774775B8 (en) | 2018-04-11 | 2023-11-15 | VIIV Healthcare UK (No.5) Limited | 4-oxo-3,4-dihydroquinazoline compounds as inhibitors of human immunodeficiency virus replication |
| US11944611B2 (en) | 2018-07-16 | 2024-04-02 | Gilead Sciences, Inc. | Capsid inhibitors for the treatment of HIV |
| CN112789086A (zh) | 2018-08-09 | 2021-05-11 | Viiv保健英国第五有限公司 | 人类免疫缺陷病毒复制的抑制剂 |
| EP3849982A1 (en) | 2018-09-14 | 2021-07-21 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
| EP3853228A1 (en) | 2018-09-20 | 2021-07-28 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
| EP3870576B1 (en) | 2018-10-24 | 2024-01-24 | VIIV Healthcare UK (No.5) Limited | Bezopyrazole derivatives as inhibitors of human immunodeficiency virus replication |
| US11541055B2 (en) | 2018-10-24 | 2023-01-03 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
| JP7500555B2 (ja) | 2018-10-25 | 2024-06-17 | ヴィーブ ヘルスケア ユーケー（ナンバー５）リミテッド | ヒト免疫不全ウイルス複製の阻害剤 |
| US20210403465A1 (en) | 2018-10-29 | 2021-12-30 | VIIV Healthcare UK (No.5) Limited | Quinazolinyl-indazole derivatives and their use as inhibitors of human immunodeficiency virus replication |
| US20210379071A1 (en) | 2018-11-05 | 2021-12-09 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
| WO2020095177A1 (en) | 2018-11-05 | 2020-05-14 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
| CA3124783A1 (en) * | 2018-12-27 | 2020-07-02 | Taisho Pharmaceutical Co., Ltd. | Pyrazolo[1,5-a]pyrimidine macrocyclic compound |
| UY38559A (es) | 2019-02-01 | 2020-07-31 | Viiv Healthcare Uk No 5 Ltd | Inhibidores de la replicación del virus de la inmunodeficiencia humana |
| EP3962603A1 (en) | 2019-04-30 | 2022-03-09 | ViiV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
| KR102932817B1 (ko) | 2019-06-19 | 2026-03-04 | 비브 헬스케어 유케이 (넘버5) 리미티드 | 인간 면역결핍 바이러스 복제의 억제제로서의 피리도[2,3-d]피리미딘 유도체 |
| JP2022551254A (ja) | 2019-10-01 | 2022-12-08 | ビーブ、ヘルスケア、ユーケー、（ナンバー５）、リミテッド | ヒト免疫不全ウイルスの複製阻害剤 |
| ES2974657T3 (es) | 2019-10-01 | 2024-07-01 | Viiv Healthcare Uk No 5 Ltd | Derivados de n-substituido-6-oxo-1,6-dihidropirimidina-2-ilo como inhibidores de la replicación del virus de inmunodeficiencia humana |
| TW202128648A (zh) | 2019-10-04 | 2021-08-01 | 英商Ｖｉｉｖ醫療保健英國(Ｎｏ 5)有限公司 | 人類免疫不全病毒複製之抑制劑 |
| US20220370451A1 (en) | 2019-10-08 | 2022-11-24 | VIIV HEALTHCARE UK ( No. 5) LIMITED | Inhibitors of human immunodeficiency virus replication |
| EP4643882A3 (en) | 2019-11-26 | 2026-01-14 | Gilead Sciences, Inc. | Capsid inhibitors for the prevention of hiv |
| EP4066839A4 (en) | 2019-11-28 | 2023-12-27 | Shionogi & Co., Ltd | PROPHYLACTIC AND THERAPEUTIC MEDICINAL PRODUCT FOR HIV INFECTIOUS DISEASES, CHARACTERIZED BY CONTAINING THE COMBINATION OF INTEGRAS INHIBITORS AND ANTI-HIV AGENTS |
| KR20220151655A (ko) | 2020-03-06 | 2022-11-15 | 비브 헬스케어 유케이 (넘버5) 리미티드 | 인간 면역결핍 바이러스 복제의 억제제 |
| WO2021176367A1 (en) | 2020-03-06 | 2021-09-10 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
| US20230149408A1 (en) | 2020-04-15 | 2023-05-18 | Viiv Healthcare Uk (No. 5) Limited | Inhibitors of human immunodeficiency virus replication |
| JP7520162B2 (ja) | 2020-06-25 | 2024-07-22 | ギリアード サイエンシーズ， インコーポレイテッド | Ｈｉｖの治療のためのカプシド阻害剤 |
| JP7765637B2 (ja) | 2021-12-03 | 2025-11-06 | ギリアード サイエンシーズ， インコーポレイテッド | Ｈｉｖウイルス感染症のための治療化合物 |
| WO2023102523A1 (en) | 2021-12-03 | 2023-06-08 | Gilead Sciences, Inc. | Therapeutic compounds for hiv virus infection |
| PT4440702T (pt) | 2021-12-03 | 2025-08-13 | Gilead Sciences Inc | Compostos terapêuticos para a infecção pelo vírus do hiv |
| EP4727909A1 (en) | 2023-06-15 | 2026-04-22 | VIIV Healthcare UK (No.5) Limited | Methods and intermediates for preparing compounds |
| US12594276B2 (en) | 2024-02-05 | 2026-04-07 | Viiv Healthcare Uk (No. 5) Limited | Inhibitors of human immunodeficiency virus replication |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ521456A (en) * | 2000-04-19 | 2004-07-30 | Schering Corp | Macrocyclic NS3-Serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties |
| MX2009013830A (es) * | 2007-06-29 | 2010-03-01 | Gilead Sciences Inc | Compuestos antivirales. |
| AU2008277377B2 (en) * | 2007-07-19 | 2013-08-01 | Msd Italia S.R.L. | Macrocyclic compounds as antiviral agents |
| WO2009062285A1 (en) | 2007-11-16 | 2009-05-22 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
| US8338441B2 (en) | 2009-05-15 | 2012-12-25 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| WO2011139637A1 (en) | 2010-05-03 | 2011-11-10 | Philadelphia Health & Education Corporation | Small-molecule modulators of hiv-1 capsid stability and methods thereof |
| PH12013500015A1 (en) | 2010-07-02 | 2013-02-18 | Gilead Sciences Inc | 2 -quinolinyl- acetic acid derivatives as hiv antiviral compounds |
| AP2013006706A0 (en) | 2010-07-02 | 2013-02-28 | Gilead Sciences Inc | Napht-2-ylacetic acid derivatives to treat AIDS |
| UA111841C2 (uk) | 2011-04-21 | 2016-06-24 | Гіліад Сайєнсіз, Інк. | Сполуки бензотіазолу та їх фармацевтичне застосування |
| ES2553449T3 (es) | 2011-07-06 | 2015-12-09 | Gilead Sciences, Inc. | Compuestos para el tratamiento de VIH |
| CN102863512B (zh) | 2011-07-07 | 2016-04-20 | 上海泓博智源医药技术有限公司 | 抗病毒化合物 |
| US9096586B2 (en) | 2012-04-20 | 2015-08-04 | Gilead Sciences, Inc. | Therapeutic compounds |
| GB201213087D0 (en) | 2012-07-24 | 2012-09-05 | Medical Res Council | Inhibition of HIV-1 infection |
| TW201443037A (zh) | 2013-01-09 | 2014-11-16 | Gilead Sciences Inc | 治療用化合物 |
| CA2896244C (en) | 2013-01-09 | 2017-07-04 | Gilead Sciences, Inc. | 5-membered heteroaryls and their use as antiviral agents |
-
2014
- 2014-01-09 US US14/151,762 patent/US9012441B2/en active Active
- 2014-01-09 JP JP2015551872A patent/JP5860197B1/ja not_active Expired - Fee Related
- 2014-01-09 PL PL14701647T patent/PL2943493T3/pl unknown
- 2014-01-09 CA CA2897268A patent/CA2897268C/en not_active Expired - Fee Related
- 2014-01-09 AU AU2014205315A patent/AU2014205315B2/en not_active Ceased
- 2014-01-09 NZ NZ631726A patent/NZ631726A/en not_active IP Right Cessation
- 2014-01-09 WO PCT/US2014/010937 patent/WO2014110296A1/en not_active Ceased
- 2014-01-09 ES ES14701647.1T patent/ES2642265T3/es active Active
- 2014-01-09 NZ NZ727792A patent/NZ727792A/en not_active IP Right Cessation
- 2014-01-09 EP EP14701647.1A patent/EP2943493B1/en active Active
- 2014-01-09 SI SI201430412T patent/SI2943493T1/sl unknown
- 2014-01-09 PT PT147016471T patent/PT2943493T/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2897268A1 (en) | 2014-07-17 |
| AU2014205315B2 (en) | 2016-11-17 |
| NZ727792A (en) | 2018-04-27 |
| WO2014110296A1 (en) | 2014-07-17 |
| AU2014205315A1 (en) | 2015-07-16 |
| US9012441B2 (en) | 2015-04-21 |
| EP2943493B1 (en) | 2017-08-02 |
| ES2642265T3 (es) | 2017-11-16 |
| SI2943493T1 (sl) | 2017-11-30 |
| EP2943493A1 (en) | 2015-11-18 |
| JP5860197B1 (ja) | 2016-02-16 |
| PT2943493T (pt) | 2017-10-23 |
| CA2897268C (en) | 2018-12-04 |
| US20140221417A1 (en) | 2014-08-07 |
| HK1216421A1 (en) | 2016-11-11 |
| NZ631726A (en) | 2017-01-27 |
| JP2016508150A (ja) | 2016-03-17 |
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