PL2818165T3 - Stała kompozycja farmaceutyczna zawierająca 1-(3-(2-(1-benzotiofen-5-ylo)etoksy)propylo)-azetydyn-3-ol albo jego sól - Google Patents
Stała kompozycja farmaceutyczna zawierająca 1-(3-(2-(1-benzotiofen-5-ylo)etoksy)propylo)-azetydyn-3-ol albo jego sólInfo
- Publication number
- PL2818165T3 PL2818165T3 PL13752248T PL13752248T PL2818165T3 PL 2818165 T3 PL2818165 T3 PL 2818165T3 PL 13752248 T PL13752248 T PL 13752248T PL 13752248 T PL13752248 T PL 13752248T PL 2818165 T3 PL2818165 T3 PL 2818165T3
- Authority
- PL
- Poland
- Prior art keywords
- benzothiophen
- azetidin
- ethoxy
- propyl
- salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/288—Compounds of unknown constitution, e.g. material from plants or animals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012035710 | 2012-02-22 | ||
| EP13752248.8A EP2818165B1 (en) | 2012-02-22 | 2013-02-21 | Solid pharmaceutical composition containing 1-(3-(2-(1-benzothiophen-5-yl) ethoxy) propyl) azetidin-3-ol or salt thereof |
| PCT/JP2013/054268 WO2013125617A1 (ja) | 2012-02-22 | 2013-02-21 | １－（３－（２－（１－ベンゾチオフェン－５－イル）エトキシ）プロピル）アゼチジン－３－オールまたはその塩を含有する固形医薬組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2818165T3 true PL2818165T3 (pl) | 2019-09-30 |
Family
ID=49005796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13752248T PL2818165T3 (pl) | 2012-02-22 | 2013-02-21 | Stała kompozycja farmaceutyczna zawierająca 1-(3-(2-(1-benzotiofen-5-ylo)etoksy)propylo)-azetydyn-3-ol albo jego sól |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9872914B2 (https=) |
| EP (1) | EP2818165B1 (https=) |
| JP (1) | JP6054940B2 (https=) |
| KR (1) | KR102070581B1 (https=) |
| CN (1) | CN104159583B (https=) |
| BR (1) | BR112014020434B1 (https=) |
| CA (1) | CA2865380C (https=) |
| DK (1) | DK2818165T3 (https=) |
| ES (1) | ES2721666T3 (https=) |
| IN (1) | IN2014DN06995A (https=) |
| PL (1) | PL2818165T3 (https=) |
| RU (1) | RU2625767C2 (https=) |
| TR (1) | TR201907882T4 (https=) |
| WO (1) | WO2013125617A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104244931A (zh) * | 2012-04-27 | 2014-12-24 | 默克专利股份有限公司 | 经包衣的片剂及其制备 |
| WO2015115512A1 (ja) * | 2014-01-29 | 2015-08-06 | 独立行政法人産業技術総合研究所 | シクロデキストリンの利用による抗がん活性が増強されたアシュワガンダ葉の水抽出物の調製方法、及びアシュワガンダ葉を含む医薬組成物 |
| BR112018011948B1 (pt) * | 2015-12-25 | 2023-10-03 | Fujifilm Toyama Chemical Co., Ltd | Comprimido compreendendo 1-(3-(2-(1-benzotiofen-5-il)etoxi)propil) azetidin-3-ol ou sal do mesmo |
| WO2018124284A1 (ja) | 2016-12-28 | 2018-07-05 | 富山化学工業株式会社 | 医薬組成物 |
| JP7057286B2 (ja) * | 2016-12-28 | 2022-04-19 | 富士フイルム富山化学株式会社 | 医薬組成物 |
| WO2018124281A1 (ja) * | 2016-12-28 | 2018-07-05 | 富山化学工業株式会社 | 外用組成物 |
| JP7079209B2 (ja) * | 2016-12-28 | 2022-06-01 | 富士フイルム富山化学株式会社 | 医薬組成物およびその製造方法 |
| SG11201911512SA (en) | 2017-06-02 | 2020-01-30 | Fujifilm Toyama Chemical Co Ltd | Agent for preventing or treating brain atrophy |
| CA3067455C (en) * | 2017-06-02 | 2021-11-23 | Fujifilm Toyama Chemical Co., Ltd. | Agent for preventing or treating spinocerebellar ataxia |
| JPWO2018221728A1 (ja) | 2017-06-02 | 2020-04-02 | 富士フイルム富山化学株式会社 | アルツハイマー型認知症予防または治療剤 |
| BR112019024983A2 (pt) | 2017-06-02 | 2020-06-23 | Fujifilm Toyama Chemical Co., Ltd. | Agente para reduzir a quantidade de proteína b amiloide |
| BR112019024878A2 (pt) * | 2017-06-02 | 2020-06-16 | Fujifilm Toyama Chemical Co., Ltd. | Agente para prevenção ou tratamento de tauopatia |
| WO2019088083A1 (ja) | 2017-10-30 | 2019-05-09 | 富士フイルム富山化学株式会社 | エモパミル結合タンパク質結合剤およびその利用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100875576B1 (ko) * | 2001-04-27 | 2008-12-23 | 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 | 이소말토오스의 제조방법 및 용도 |
| JP4905752B2 (ja) | 2001-07-24 | 2012-03-28 | エスティー・ラボ株式会社 | 揮発性有機塩素化合物センサ |
| IL161308A0 (en) | 2001-10-19 | 2004-09-27 | Toyama Chemical Co Ltd | Alkyl ether derivatives or their salts |
| US7118765B2 (en) * | 2001-12-17 | 2006-10-10 | Spi Pharma, Inc. | Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms |
| JP4090309B2 (ja) | 2002-08-30 | 2008-05-28 | 帝人株式会社 | 全芳香族ポリエステルカーボネート系樹脂組成物 |
| PT1614419E (pt) * | 2003-04-17 | 2012-10-22 | Toyama Chemical Co Ltd | Medicamentos para a prevenção ou o tratamento de doenças do nervo da retina contendo derivados de éter de alquilo ou os seus sais |
| US7838029B1 (en) * | 2003-07-31 | 2010-11-23 | Watson Laboratories, Inc. | Mirtazapine solid dosage forms |
| EP1817009A2 (en) * | 2004-11-24 | 2007-08-15 | Spi Pharma, Inc. | Orally disintegrating compositions |
| ES2398934T3 (es) | 2005-03-28 | 2013-03-22 | Toyama Chemical Co., Ltd. | Proceso de la producción de1-(3-(2-(1-benzotiofen-5-il)etoxi)propil)acetidin-ol o sales del mismo |
| RU2397169C2 (ru) * | 2005-03-28 | 2010-08-20 | Тояма Кемикал Ко., Лтд. | Способ получения 1-(3-(2-(1-бензотиофен-5-ил)этокси) пропил)азетидин-3-ола или его солей |
| JP2007137802A (ja) * | 2005-11-16 | 2007-06-07 | Takeda Chem Ind Ltd | 錠剤の製造法 |
| US20070196494A1 (en) * | 2006-02-17 | 2007-08-23 | Arnaud Grenier | Low-friability, patient-friendly orally disintegrating formulations |
| US20090208576A1 (en) * | 2006-03-31 | 2009-08-20 | Gandhi Anilkumar S | Orally Disintegrating Tablets |
| US8119625B2 (en) * | 2006-04-26 | 2012-02-21 | Toyama Chemical Co., Ltd. | Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof |
| DK2048145T3 (da) * | 2006-08-04 | 2011-04-04 | Toyama Chemical Co Ltd | Forstærker af aktiviteten af proteinkinase C indeholdende alkyletherderivat eller et salt deraf |
| US20100215740A1 (en) * | 2007-10-10 | 2010-08-26 | Rubicon Research Private Limited | Taste-masked orally disintegrating tablets of memantine hydrochloride |
| DK2287160T3 (da) * | 2008-05-28 | 2014-06-10 | Toyama Chemical Co Ltd | Benzothiophenoxidderivat og salt deraf |
-
2013
- 2013-02-21 CN CN201380010472.9A patent/CN104159583B/zh active Active
- 2013-02-21 KR KR1020147023511A patent/KR102070581B1/ko active Active
- 2013-02-21 TR TR2019/07882T patent/TR201907882T4/tr unknown
- 2013-02-21 EP EP13752248.8A patent/EP2818165B1/en active Active
- 2013-02-21 US US14/379,960 patent/US9872914B2/en active Active
- 2013-02-21 BR BR112014020434-9A patent/BR112014020434B1/pt active IP Right Grant
- 2013-02-21 CA CA2865380A patent/CA2865380C/en active Active
- 2013-02-21 PL PL13752248T patent/PL2818165T3/pl unknown
- 2013-02-21 ES ES13752248T patent/ES2721666T3/es active Active
- 2013-02-21 DK DK13752248.8T patent/DK2818165T3/da active
- 2013-02-21 WO PCT/JP2013/054268 patent/WO2013125617A1/ja not_active Ceased
- 2013-02-21 IN IN6995DEN2014 patent/IN2014DN06995A/en unknown
- 2013-02-21 RU RU2014138035A patent/RU2625767C2/ru active
- 2013-02-21 JP JP2014500753A patent/JP6054940B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2721666T3 (es) | 2019-08-02 |
| KR102070581B1 (ko) | 2020-01-29 |
| EP2818165B1 (en) | 2019-04-10 |
| KR20150001720A (ko) | 2015-01-06 |
| EP2818165A4 (en) | 2015-07-08 |
| US9872914B2 (en) | 2018-01-23 |
| TR201907882T4 (tr) | 2019-06-21 |
| CN104159583B (zh) | 2018-04-13 |
| DK2818165T3 (da) | 2019-06-03 |
| RU2014138035A (ru) | 2016-04-10 |
| BR112014020434B1 (pt) | 2021-10-13 |
| CA2865380A1 (en) | 2013-08-29 |
| WO2013125617A1 (ja) | 2013-08-29 |
| US20150045345A1 (en) | 2015-02-12 |
| CN104159583A (zh) | 2014-11-19 |
| EP2818165A1 (en) | 2014-12-31 |
| RU2625767C2 (ru) | 2017-07-18 |
| CA2865380C (en) | 2019-10-29 |
| IN2014DN06995A (https=) | 2015-04-10 |
| JP6054940B2 (ja) | 2016-12-27 |
| JPWO2013125617A1 (ja) | 2015-07-30 |
| BR112014020434A2 (https=) | 2017-06-20 |
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