PL2714661T3 - Pochodne kwasu pikolinamidopropanowego przydatne jako antagoniści receptora glukagonu - Google Patents
Pochodne kwasu pikolinamidopropanowego przydatne jako antagoniści receptora glukagonuInfo
- Publication number
- PL2714661T3 PL2714661T3 PL12724507T PL12724507T PL2714661T3 PL 2714661 T3 PL2714661 T3 PL 2714661T3 PL 12724507 T PL12724507 T PL 12724507T PL 12724507 T PL12724507 T PL 12724507T PL 2714661 T3 PL2714661 T3 PL 2714661T3
- Authority
- PL
- Poland
- Prior art keywords
- picolinamido
- acid derivatives
- propanoic acid
- receptor antagonists
- glucagon receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161488842P | 2011-05-23 | 2011-05-23 | |
| PCT/US2012/039171 WO2012162407A1 (en) | 2011-05-23 | 2012-05-23 | Picolinamido - propanoic acid derivatives useful as glucagon receptor antagonists |
| EP12724507.4A EP2714661B1 (en) | 2011-05-23 | 2012-05-23 | Picolinamido - propanoic acid derivatives useful as glucagon receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2714661T3 true PL2714661T3 (pl) | 2016-03-31 |
Family
ID=46178849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12724507T PL2714661T3 (pl) | 2011-05-23 | 2012-05-23 | Pochodne kwasu pikolinamidopropanowego przydatne jako antagoniści receptora glukagonu |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8748624B2 (pl) |
| EP (1) | EP2714661B1 (pl) |
| JP (1) | JP2014515370A (pl) |
| CN (1) | CN103547570A (pl) |
| AU (1) | AU2012258771A1 (pl) |
| CA (1) | CA2837079A1 (pl) |
| DK (1) | DK2714661T3 (pl) |
| ES (1) | ES2557450T3 (pl) |
| ME (1) | ME02228B (pl) |
| MX (1) | MX2013013731A (pl) |
| PL (1) | PL2714661T3 (pl) |
| PT (1) | PT2714661E (pl) |
| WO (1) | WO2012162407A1 (pl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200730474A (en) | 2005-12-29 | 2007-08-16 | Schering Ag | Diamine derivatives as inhibitors of leukotriene A4 hydrolease |
| PT2714647E (pt) | 2011-05-23 | 2015-09-02 | Janssen Pharmaceutica Nv | Derivativos bifenil usados como antagonistas do recetor da glicagina |
| ES2864862T3 (es) | 2013-03-12 | 2021-10-14 | Celltaxis Llc | Métodos de inhibición de la leucotrieno A4 hidrolasa |
| WO2014152518A2 (en) | 2013-03-14 | 2014-09-25 | Celtaxsys, Inc. | Inhibitors of leukotriene a4 hydrolase |
| KR20150131211A (ko) * | 2013-03-14 | 2015-11-24 | 켈탁시스, 인코퍼레이티드 | 류코트라이엔 a4 가수분해효소의 저해제 |
| MX2015011677A (es) | 2013-03-14 | 2016-07-08 | Celtaxsys Inc | Inhibidores de leucotrieno a4 hidrolasa. |
| TWI763705B (zh) * | 2016-09-06 | 2022-05-11 | 比利時商健生藥品公司 | 可作為升糖素受體拮抗劑之吲哚衍生物 |
| TWI757332B (zh) | 2016-09-06 | 2022-03-11 | 比利時商健生藥品公司 | 使用作為升糖素受體拮抗劑之吲唑衍生物 |
| TW201811752A (zh) * | 2016-09-06 | 2018-04-01 | 比利時商健生藥品公司 | 用作升糖素受體拮抗劑之吲唑衍生物 |
| WO2019232306A1 (en) | 2018-05-31 | 2019-12-05 | Celtaxsys, Inc. | Method of reducing pulmonary exacerbations in respiratory disease patients |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0802191A4 (en) | 1995-10-13 | 2001-08-01 | Otsuka Kagaku Kk | PYRAZOLE DERIVATIVES AND INSECTICIDE COMPOSITIONS CONTAINING SUCH DERIVATIVES AS ACTIVE INGREDIENTS |
| CN1356977A (zh) * | 1999-05-17 | 2002-07-03 | 诺沃挪第克公司 | 胰高血糖素拮抗剂/反向激动剂 |
| EP1463715A1 (en) * | 2001-12-03 | 2004-10-06 | Novo Nordisk A/S | Novel glucagon antagonists |
| AU2003291959A1 (en) * | 2002-12-20 | 2004-07-14 | Novo Nordisk A/S | Novel glucagon antagonists |
| CA2619101A1 (en) * | 2005-08-23 | 2007-03-01 | Irm Llc | Immunosuppressant compounds and compositions |
| PT1951661E (pt) * | 2005-11-17 | 2012-09-19 | Lilly Co Eli | Antagonistas do receptor de glucagon, preparação e utilizações terapêuticas |
| JP2009530381A (ja) * | 2006-03-23 | 2009-08-27 | メルク エンド カムパニー インコーポレーテッド | グルカゴン受容体アンタゴニスト化合物、この化合物を含む組成物及び使用方法 |
-
2012
- 2012-05-23 MX MX2013013731A patent/MX2013013731A/es not_active Application Discontinuation
- 2012-05-23 JP JP2014512077A patent/JP2014515370A/ja active Pending
- 2012-05-23 PT PT127245074T patent/PT2714661E/pt unknown
- 2012-05-23 WO PCT/US2012/039171 patent/WO2012162407A1/en active Application Filing
- 2012-05-23 AU AU2012258771A patent/AU2012258771A1/en not_active Abandoned
- 2012-05-23 DK DK12724507.4T patent/DK2714661T3/en active
- 2012-05-23 ME MEP-2015-171A patent/ME02228B/me unknown
- 2012-05-23 PL PL12724507T patent/PL2714661T3/pl unknown
- 2012-05-23 CN CN201280025063.1A patent/CN103547570A/zh active Pending
- 2012-05-23 CA CA2837079A patent/CA2837079A1/en not_active Abandoned
- 2012-05-23 EP EP12724507.4A patent/EP2714661B1/en active Active
- 2012-05-23 US US13/478,534 patent/US8748624B2/en active Active
- 2012-05-23 ES ES12724507.4T patent/ES2557450T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2557450T3 (es) | 2016-01-26 |
| US8748624B2 (en) | 2014-06-10 |
| MX2013013731A (es) | 2014-02-27 |
| EP2714661B1 (en) | 2015-09-30 |
| DK2714661T3 (en) | 2015-10-19 |
| CN103547570A (zh) | 2014-01-29 |
| CA2837079A1 (en) | 2012-11-29 |
| EP2714661A1 (en) | 2014-04-09 |
| AU2012258771A1 (en) | 2013-11-14 |
| ME02228B (me) | 2016-02-20 |
| JP2014515370A (ja) | 2014-06-30 |
| US20120302610A1 (en) | 2012-11-29 |
| WO2012162407A1 (en) | 2012-11-29 |
| PT2714661E (pt) | 2016-01-22 |
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