PL2714661T3 - Pochodne kwasu pikolinamidopropanowego przydatne jako antagoniści receptora glukagonu - Google Patents
Pochodne kwasu pikolinamidopropanowego przydatne jako antagoniści receptora glukagonuInfo
- Publication number
- PL2714661T3 PL2714661T3 PL12724507T PL12724507T PL2714661T3 PL 2714661 T3 PL2714661 T3 PL 2714661T3 PL 12724507 T PL12724507 T PL 12724507T PL 12724507 T PL12724507 T PL 12724507T PL 2714661 T3 PL2714661 T3 PL 2714661T3
- Authority
- PL
- Poland
- Prior art keywords
- picolinamido
- acid derivatives
- propanoic acid
- receptor antagonists
- glucagon receptor
- Prior art date
Links
- PDGMKIQFTNALCB-UHFFFAOYSA-N 2-(pyridine-2-carbonylamino)propanoic acid Chemical class OC(=O)C(C)NC(=O)C1=CC=CC=N1 PDGMKIQFTNALCB-UHFFFAOYSA-N 0.000 title 1
- 229940122904 Glucagon receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161488842P | 2011-05-23 | 2011-05-23 | |
| PCT/US2012/039171 WO2012162407A1 (en) | 2011-05-23 | 2012-05-23 | Picolinamido - propanoic acid derivatives useful as glucagon receptor antagonists |
| EP12724507.4A EP2714661B1 (en) | 2011-05-23 | 2012-05-23 | Picolinamido - propanoic acid derivatives useful as glucagon receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2714661T3 true PL2714661T3 (pl) | 2016-03-31 |
Family
ID=46178849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12724507T PL2714661T3 (pl) | 2011-05-23 | 2012-05-23 | Pochodne kwasu pikolinamidopropanowego przydatne jako antagoniści receptora glukagonu |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8748624B2 (pl) |
| EP (1) | EP2714661B1 (pl) |
| JP (1) | JP2014515370A (pl) |
| CN (1) | CN103547570A (pl) |
| AU (1) | AU2012258771A1 (pl) |
| CA (1) | CA2837079A1 (pl) |
| DK (1) | DK2714661T3 (pl) |
| ES (1) | ES2557450T3 (pl) |
| ME (1) | ME02228B (pl) |
| MX (1) | MX2013013731A (pl) |
| PL (1) | PL2714661T3 (pl) |
| PT (1) | PT2714661E (pl) |
| WO (1) | WO2012162407A1 (pl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1976828T3 (pl) | 2005-12-29 | 2017-07-31 | Celtaxsys, Inc. | Pochodne diaminy jako inhibitory hydrolazy leukotrienu a4 |
| PT2714647E (pt) | 2011-05-23 | 2015-09-02 | Janssen Pharmaceutica Nv | Derivativos bifenil usados como antagonistas do recetor da glicagina |
| JP6527851B2 (ja) | 2013-03-12 | 2019-06-05 | セルタクシス，インコーポレイテッド | ロイコトリエンａ４加水分解酵素を阻害する方法 |
| AU2014239585B2 (en) | 2013-03-14 | 2019-04-04 | Celtaxsys, Inc. | Inhibitors of leukotriene A4 hydrolase |
| EP2968264A4 (en) | 2013-03-14 | 2016-11-02 | Celtaxsys Inc | INHIBITORS OF LEUCOTRIENE A4 HYDROLASE |
| AU2014239567B2 (en) | 2013-03-14 | 2017-12-14 | Celtaxsys, Inc. | Inhibitors of leukotriene A4 hydrolase |
| TWI763705B (zh) * | 2016-09-06 | 2022-05-11 | 比利時商健生藥品公司 | 可作為升糖素受體拮抗劑之吲哚衍生物 |
| TWI757332B (zh) | 2016-09-06 | 2022-03-11 | 比利時商健生藥品公司 | 使用作為升糖素受體拮抗劑之吲唑衍生物 |
| TW201811752A (zh) | 2016-09-06 | 2018-04-01 | 比利時商健生藥品公司 | 用作升糖素受體拮抗劑之吲唑衍生物 |
| CA3102077A1 (en) | 2018-05-31 | 2019-12-05 | Sanjeev AHUJA | Method of reducing pulmonary exacerbations in respiratory disease patients |
| CN117964466A (zh) * | 2024-01-09 | 2024-05-03 | 长沙贝塔医药科技有限公司 | 一种合成[13c]4-溴-2-氯-6-氟-苯甲醛的方法 |
| WO2025248032A1 (en) | 2024-05-31 | 2025-12-04 | Syngenta Crop Protection Ag | Pesticidally active indazole compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0802191A4 (en) | 1995-10-13 | 2001-08-01 | Otsuka Kagaku Kk | PYRAZOLE DERIVATIVES AND INSECTICIDE COMPOSITIONS CONTAINING SUCH DERIVATIVES AS ACTIVE INGREDIENTS |
| AU4537900A (en) * | 1999-05-17 | 2000-12-05 | Agouron Pharmaceuticals, Inc. | Glucagon antagonists/inverse agonists |
| EP1463715A1 (en) * | 2001-12-03 | 2004-10-06 | Novo Nordisk A/S | Novel glucagon antagonists |
| WO2004056763A2 (en) * | 2002-12-20 | 2004-07-08 | Novo Nordisk A/S | Novel glucagon antagonists |
| CA2619101A1 (en) | 2005-08-23 | 2007-03-01 | Irm Llc | Immunosuppressant compounds and compositions |
| CN101309895B (zh) * | 2005-11-17 | 2012-10-03 | 伊莱利利公司 | 胰高血糖素受体拮抗剂、制备和治疗用途 |
| EP2001472A2 (en) | 2006-03-23 | 2008-12-17 | Merck and Co., Inc. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
-
2012
- 2012-05-23 CA CA2837079A patent/CA2837079A1/en not_active Abandoned
- 2012-05-23 MX MX2013013731A patent/MX2013013731A/es not_active Application Discontinuation
- 2012-05-23 EP EP12724507.4A patent/EP2714661B1/en active Active
- 2012-05-23 US US13/478,534 patent/US8748624B2/en active Active
- 2012-05-23 CN CN201280025063.1A patent/CN103547570A/zh active Pending
- 2012-05-23 WO PCT/US2012/039171 patent/WO2012162407A1/en not_active Ceased
- 2012-05-23 PL PL12724507T patent/PL2714661T3/pl unknown
- 2012-05-23 JP JP2014512077A patent/JP2014515370A/ja active Pending
- 2012-05-23 DK DK12724507.4T patent/DK2714661T3/en active
- 2012-05-23 ME MEP-2015-171A patent/ME02228B/me unknown
- 2012-05-23 ES ES12724507.4T patent/ES2557450T3/es active Active
- 2012-05-23 PT PT127245074T patent/PT2714661E/pt unknown
- 2012-05-23 AU AU2012258771A patent/AU2012258771A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ME02228B (me) | 2016-02-20 |
| AU2012258771A1 (en) | 2013-11-14 |
| CA2837079A1 (en) | 2012-11-29 |
| MX2013013731A (es) | 2014-02-27 |
| EP2714661B1 (en) | 2015-09-30 |
| CN103547570A (zh) | 2014-01-29 |
| EP2714661A1 (en) | 2014-04-09 |
| JP2014515370A (ja) | 2014-06-30 |
| US20120302610A1 (en) | 2012-11-29 |
| US8748624B2 (en) | 2014-06-10 |
| ES2557450T3 (es) | 2016-01-26 |
| DK2714661T3 (en) | 2015-10-19 |
| PT2714661E (pt) | 2016-01-22 |
| WO2012162407A1 (en) | 2012-11-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT2714661E (pt) | Derivados de ácido picolinamido propanóico úteis como antagonistas do recetor de glucagona | |
| SG2014011555A (en) | Lysophosphatidic acid receptor antagonists | |
| AP3391A (en) | 2-Amino-4-arylthiazole compounds as TROA1 antagonists | |
| ZA201307119B (en) | Double-acylated glp-1 derivatives | |
| ZA201306005B (en) | Novel sulfonaminoquinoline hepcidin antagonists | |
| IL229732A0 (en) | Long-acting glucagon\1 -glp receptor agonists | |
| IL230061B (en) | Glucagon/1–glp receptor co-agonists | |
| IL236688A0 (en) | Beta amino acid derivatives as integrin antagonists | |
| IL229320A0 (en) | History of 3-spirocyclic piperidines as ghrelin receptor agonists | |
| PL2736918T3 (pl) | Antagoniści progesteronu | |
| IL232503A (en) | H2 - Indazoles as antagonists of the ep2 receptor | |
| ZA201305576B (en) | Trpm8 receptor antagonists | |
| ZA201404499B (en) | Trpm8 antagonists | |
| IL233485A0 (en) | History of spiroindoline as gonadotropin-releasing hormone receptor antagonists | |
| IL226920A (en) | Pyrazole compounds as antagonists of crth2 | |
| PT2714647E (pt) | Derivativos bifenil usados como antagonistas do recetor da glicagina | |
| IL232985A0 (en) | Cycloalkane carboxylic acid derivatives as cxcr3 receptor inhibitors | |
| IL230334A0 (en) | Non-competitive nicotinic receptor antagonists | |
| GB201213699D0 (en) | Receptor antagonists II | |
| GB201213698D0 (en) | Receptor antagonists II |