PT2714661E - Derivados de ácido picolinamido propanóico úteis como antagonistas do recetor de glucagona - Google Patents
Derivados de ácido picolinamido propanóico úteis como antagonistas do recetor de glucagona Download PDFInfo
- Publication number
- PT2714661E PT2714661E PT127245074T PT12724507T PT2714661E PT 2714661 E PT2714661 E PT 2714661E PT 127245074 T PT127245074 T PT 127245074T PT 12724507 T PT12724507 T PT 12724507T PT 2714661 E PT2714661 E PT 2714661E
- Authority
- PT
- Portugal
- Prior art keywords
- picolinamido
- acid derivatives
- propanoic acid
- receptor antagonists
- glucagon receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161488842P | 2011-05-23 | 2011-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2714661E true PT2714661E (pt) | 2016-01-22 |
Family
ID=46178849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT127245074T PT2714661E (pt) | 2011-05-23 | 2012-05-23 | Derivados de ácido picolinamido propanóico úteis como antagonistas do recetor de glucagona |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8748624B2 (pt) |
| EP (1) | EP2714661B1 (pt) |
| JP (1) | JP2014515370A (pt) |
| CN (1) | CN103547570A (pt) |
| AU (1) | AU2012258771A1 (pt) |
| CA (1) | CA2837079A1 (pt) |
| DK (1) | DK2714661T3 (pt) |
| ES (1) | ES2557450T3 (pt) |
| ME (1) | ME02228B (pt) |
| MX (1) | MX2013013731A (pt) |
| PL (1) | PL2714661T3 (pt) |
| PT (1) | PT2714661E (pt) |
| WO (1) | WO2012162407A1 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT1976828T (lt) | 2005-12-29 | 2017-04-25 | Celtaxsys, Inc. | Diamino dariniai, kaip leukotrieno a4 hidrolazės inhibitoriai |
| US9045389B2 (en) | 2011-05-23 | 2015-06-02 | Janssen Pharmaceutica Nv | Biphenyl derivatives useful as glucagon receptor antagonists |
| AU2014249168B2 (en) | 2013-03-12 | 2018-07-12 | Celltaxis, Llc | Methods of inhibiting leukotriene A4 hydrolase |
| CA2906086A1 (en) * | 2013-03-14 | 2014-09-25 | Celtaxsys, Inc. | Inhibitors of leukotriene a4 hydrolase |
| RU2696559C2 (ru) | 2013-03-14 | 2019-08-05 | Селтакссис, Инк. | Ингибиторы лейкотриен а4-гидролазы |
| EP2970309A4 (en) | 2013-03-14 | 2016-11-09 | Celtaxsys Inc | INHIBITORS OF LEUCOTRIENE A4 HYDROLASE |
| TWI763705B (zh) * | 2016-09-06 | 2022-05-11 | 比利時商健生藥品公司 | 可作為升糖素受體拮抗劑之吲哚衍生物 |
| TWI757332B (zh) * | 2016-09-06 | 2022-03-11 | 比利時商健生藥品公司 | 使用作為升糖素受體拮抗劑之吲唑衍生物 |
| TW201811752A (zh) | 2016-09-06 | 2018-04-01 | 比利時商健生藥品公司 | 用作升糖素受體拮抗劑之吲唑衍生物 |
| EP3801559A4 (en) | 2018-05-31 | 2022-03-02 | Celltaxis, LLC | METHOD FOR REDUCING LUNG EXACERBATIONS IN PATIENTS SUFFERING FROM RESPIRATORY DISEASE |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0802191A4 (en) | 1995-10-13 | 2001-08-01 | Otsuka Kagaku Kk | PYRAZOLE DERIVATIVES AND INSECTICIDE COMPOSITIONS CONTAINING SUCH DERIVATIVES AS ACTIVE INGREDIENTS |
| IL146006A0 (en) * | 1999-05-17 | 2002-07-25 | Novo Nordisk As | Glucagon antagonists/inverse agonists |
| EP1463715A1 (en) | 2001-12-03 | 2004-10-06 | Novo Nordisk A/S | Novel glucagon antagonists |
| WO2004056763A2 (en) * | 2002-12-20 | 2004-07-08 | Novo Nordisk A/S | Novel glucagon antagonists |
| CA2619101A1 (en) | 2005-08-23 | 2007-03-01 | Irm Llc | Immunosuppressant compounds and compositions |
| US7696248B2 (en) * | 2005-11-17 | 2010-04-13 | Eli Lilly And Company | Glucagon receptor antagonists, preparation and therapeutic uses |
| US7989472B2 (en) * | 2006-03-23 | 2011-08-02 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
-
2012
- 2012-05-23 JP JP2014512077A patent/JP2014515370A/ja active Pending
- 2012-05-23 MX MX2013013731A patent/MX2013013731A/es not_active Application Discontinuation
- 2012-05-23 AU AU2012258771A patent/AU2012258771A1/en not_active Abandoned
- 2012-05-23 PT PT127245074T patent/PT2714661E/pt unknown
- 2012-05-23 EP EP12724507.4A patent/EP2714661B1/en active Active
- 2012-05-23 ME MEP-2015-171A patent/ME02228B/me unknown
- 2012-05-23 CA CA2837079A patent/CA2837079A1/en not_active Abandoned
- 2012-05-23 ES ES12724507.4T patent/ES2557450T3/es active Active
- 2012-05-23 US US13/478,534 patent/US8748624B2/en active Active
- 2012-05-23 DK DK12724507.4T patent/DK2714661T3/en active
- 2012-05-23 CN CN201280025063.1A patent/CN103547570A/zh active Pending
- 2012-05-23 WO PCT/US2012/039171 patent/WO2012162407A1/en active Application Filing
- 2012-05-23 PL PL12724507T patent/PL2714661T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2013013731A (es) | 2014-02-27 |
| DK2714661T3 (en) | 2015-10-19 |
| PL2714661T3 (pl) | 2016-03-31 |
| WO2012162407A1 (en) | 2012-11-29 |
| ES2557450T3 (es) | 2016-01-26 |
| EP2714661B1 (en) | 2015-09-30 |
| US8748624B2 (en) | 2014-06-10 |
| CN103547570A (zh) | 2014-01-29 |
| US20120302610A1 (en) | 2012-11-29 |
| ME02228B (me) | 2016-02-20 |
| EP2714661A1 (en) | 2014-04-09 |
| CA2837079A1 (en) | 2012-11-29 |
| JP2014515370A (ja) | 2014-06-30 |
| AU2012258771A1 (en) | 2013-11-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1199259A1 (en) | Lysophosphatidic acid receptor antagonists | |
| HK1191008A1 (zh) | 作爲 拮抗劑的 -氨基- -芳基噻唑化合物 | |
| ME02228B (me) | Derivati pikolinamido- propanske kisjelne koji su korisni kao antagonisti receptora glukagona | |
| EP2665707A4 (en) | Mineralocorticoid receptor antagonists | |
| HUE039607T2 (hu) | Progeszteron antagonisták | |
| HK1203938A1 (en) | Novel 2h-indazoles as ep2 receptor antagonists ep2 2h- | |
| HK1192228A1 (zh) | 受體拮抗劑 | |
| HK1199878A1 (en) | Spiroindoline derivatives as gonadotropin-releasing hormone receptor antagonists | |
| IL229320A0 (en) | History of 3-spirocyclic piperidines as ghrelin receptor agonists | |
| EP2765860A4 (en) | Mineralocorticoid receptor antagonists | |
| EP2627329A4 (en) | TRPA1 RECEPTOR ANTAGONIST | |
| EP2697203A4 (en) | ANTAGONISTS OF MINERALOCORTICOID RECEPTORS | |
| HK1215247A1 (zh) | 作為 拮抗劑的吡唑化合物 | |
| EP2765859A4 (en) | Mineralocorticoid receptor antagonists | |
| EP2765858A4 (en) | ANTAGONISTS OF A MINERALOCORTICOID RECEPTOR | |
| PL2714647T3 (pl) | Pochodne bifenylu przydatne jako antagoniści receptora glukagonu | |
| IL232985A0 (en) | Cycloalkane carboxylic acid derivatives as cxcr3 receptor inhibitors | |
| IL230334A0 (en) | Non-competitive nicotinic receptor antagonists | |
| GB201213698D0 (en) | Receptor antagonists II | |
| GB201213699D0 (en) | Receptor antagonists II |