PL2714647T3 - Pochodne bifenylu przydatne jako antagoniści receptora glukagonu - Google Patents

Pochodne bifenylu przydatne jako antagoniści receptora glukagonu

Info

Publication number
PL2714647T3
PL2714647T3 PL12724508T PL12724508T PL2714647T3 PL 2714647 T3 PL2714647 T3 PL 2714647T3 PL 12724508 T PL12724508 T PL 12724508T PL 12724508 T PL12724508 T PL 12724508T PL 2714647 T3 PL2714647 T3 PL 2714647T3
Authority
PL
Poland
Prior art keywords
receptor antagonists
glucagon receptor
derivatives useful
biphenyl derivatives
biphenyl
Prior art date
Application number
PL12724508T
Other languages
English (en)
Inventor
Devraj Chakravarty
Michael N Greco
Brian Shook
Guozhang Xu
Rui Zhang
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PL2714647T3 publication Critical patent/PL2714647T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/36Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL12724508T 2011-05-23 2012-05-23 Pochodne bifenylu przydatne jako antagoniści receptora glukagonu PL2714647T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161488848P 2011-05-23 2011-05-23
PCT/US2012/039173 WO2012162409A1 (en) 2011-05-23 2012-05-23 Biphenyl derivatives useful as glucagon receptor antagonists
EP20120724508 EP2714647B1 (en) 2011-05-23 2012-05-23 Biphenyl derivatives useful as glucagon receptor antagonists

Publications (1)

Publication Number Publication Date
PL2714647T3 true PL2714647T3 (pl) 2015-09-30

Family

ID=46178850

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12724508T PL2714647T3 (pl) 2011-05-23 2012-05-23 Pochodne bifenylu przydatne jako antagoniści receptora glukagonu

Country Status (12)

Country Link
US (1) US9045389B2 (pl)
EP (1) EP2714647B1 (pl)
JP (1) JP2014520093A (pl)
CN (1) CN103547563B (pl)
AU (1) AU2012258773A1 (pl)
CA (1) CA2837088A1 (pl)
DK (1) DK2714647T3 (pl)
ES (1) ES2544104T3 (pl)
MX (1) MX2013013732A (pl)
PL (1) PL2714647T3 (pl)
PT (1) PT2714647E (pl)
WO (1) WO2012162409A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10343716B2 (en) * 2017-04-03 2019-07-09 Robby Gordon Universal axle-hub assembly
CN116868999B (zh) * 2023-07-10 2025-08-22 山东大明消毒科技有限公司 一种二溴海因泡腾片及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0802191A4 (en) 1995-10-13 2001-08-01 Otsuka Kagaku Kk PYRAZOLE DERIVATIVES AND INSECTICIDE COMPOSITIONS CONTAINING SUCH DERIVATIVES AS ACTIVE INGREDIENTS
AU4537900A (en) * 1999-05-17 2000-12-05 Agouron Pharmaceuticals, Inc. Glucagon antagonists/inverse agonists
EP1463715A1 (en) * 2001-12-03 2004-10-06 Novo Nordisk A/S Novel glucagon antagonists
WO2004056763A2 (en) 2002-12-20 2004-07-08 Novo Nordisk A/S Novel glucagon antagonists
JP2007191461A (ja) * 2005-05-23 2007-08-02 Japan Tobacco Inc ピラゾール化合物及びそれらピラゾール化合物を含んでなる糖尿病治療薬
CA2619101A1 (en) 2005-08-23 2007-03-01 Irm Llc Immunosuppressant compounds and compositions
CN101309895B (zh) * 2005-11-17 2012-10-03 伊莱利利公司 胰高血糖素受体拮抗剂、制备和治疗用途
EP2001472A2 (en) 2006-03-23 2008-12-17 Merck and Co., Inc. Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
CN101932562B (zh) * 2007-12-20 2013-06-12 阿斯利康(瑞典)有限公司 作为dgat1抑制剂190的氨基甲酰基化合物
CA2837079A1 (en) 2011-05-23 2012-11-29 Janssen Pharmaceutica Nv Picolinamido-propanoic acid derivatives useful as glucagon receptor antagonists

Also Published As

Publication number Publication date
WO2012162409A1 (en) 2012-11-29
ES2544104T3 (es) 2015-08-27
MX2013013732A (es) 2014-02-27
US20120302641A1 (en) 2012-11-29
EP2714647B1 (en) 2015-04-29
AU2012258773A1 (en) 2013-11-14
CN103547563A (zh) 2014-01-29
PT2714647E (pt) 2015-09-02
US9045389B2 (en) 2015-06-02
EP2714647A1 (en) 2014-04-09
DK2714647T3 (en) 2015-05-26
CA2837088A1 (en) 2012-11-29
JP2014520093A (ja) 2014-08-21
CN103547563B (zh) 2016-03-23

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