PL2603507T3 - Synteza związków tiazolidynodionu - Google Patents

Synteza związków tiazolidynodionu

Info

Publication number
PL2603507T3
PL2603507T3 PL11745671.5T PL11745671T PL2603507T3 PL 2603507 T3 PL2603507 T3 PL 2603507T3 PL 11745671 T PL11745671 T PL 11745671T PL 2603507 T3 PL2603507 T3 PL 2603507T3
Authority
PL
Poland
Prior art keywords
synthesis
thiazolidinedione compounds
thiazolidinedione
compounds
Prior art date
Application number
PL11745671.5T
Other languages
English (en)
Inventor
Steven P. Tanis
Timothy Parker
Robert C. Gadwood
James R. Zeller
Gerald D. Artman Iii
Scott D. Larsen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2603507T3 publication Critical patent/PL2603507T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL11745671.5T 2010-08-10 2011-08-09 Synteza związków tiazolidynodionu PL2603507T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37226910P 2010-08-10 2010-08-10

Publications (1)

Publication Number Publication Date
PL2603507T3 true PL2603507T3 (pl) 2016-12-30

Family

ID=44504274

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11745671.5T PL2603507T3 (pl) 2010-08-10 2011-08-09 Synteza związków tiazolidynodionu

Country Status (14)

Country Link
US (2) US8895748B2 (pl)
EP (1) EP2603507B1 (pl)
JP (1) JP5851506B2 (pl)
KR (1) KR101857307B1 (pl)
CN (1) CN103153991B (pl)
AU (1) AU2011289627B2 (pl)
CA (1) CA2807815C (pl)
ES (1) ES2588769T3 (pl)
HU (1) HUE029488T2 (pl)
MX (1) MX342289B (pl)
NZ (1) NZ606597A (pl)
PL (1) PL2603507T3 (pl)
RU (1) RU2594725C2 (pl)
WO (1) WO2012021467A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011133442A1 (en) 2010-04-19 2011-10-27 Metabolic Solutions Development Company Novel synthesis for thiazolidinedione compounds
ES2609837T3 (es) * 2010-08-10 2017-04-24 Octeta Therapeutics, Llc Nueva síntesis de compuestos de tiazolidindiona
CN104496935A (zh) * 2014-11-24 2015-04-08 苏州乔纳森新材料科技有限公司 一种胰岛素增敏剂中间体的合成方法
EP3436434B1 (en) 2016-03-31 2020-07-08 Oncternal Therapeutics, Inc. Indoline analogs and uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
SU1766260A3 (ru) * 1989-11-04 1992-09-30 Пфайзер Инк (Фирма) Способ получени производных тиазолидиндиона-2,4 или их фармацевтически приемлемых солей с щелочными металлами
US5143930A (en) 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
DE69231886T2 (de) * 1991-04-11 2002-03-28 Upjohn Co Thiazolidindionderivate, herstellung und anwendung
SE9702305D0 (sv) 1997-06-17 1997-06-17 Astra Ab New thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives
AP869A (en) 1998-01-05 2000-09-04 Pfizer 2,3-Substituted indole compounds as anti-inflammatory and analgesic agents.
US7407978B2 (en) 1999-04-06 2008-08-05 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2004514703A (ja) 2000-12-01 2004-05-20 ノバルティス アクチエンゲゼルシャフト 有機化合物の組合せ剤
WO2003029251A1 (en) * 2001-09-28 2003-04-10 Biocon Limited Novel process for the synthesis of thiazolidinedione derivatives
FR2861069B1 (fr) * 2003-10-17 2005-12-09 Galderma Res & Dev NOUVEAUX LIGANDS ACTIVATEURS DES RECEPTEURS RARs, UTILISATION EN MEDECINE HUMAINE AINSI QU'EN COSMETIQUE
MX2008011871A (es) * 2006-03-16 2009-02-10 Metabolic Solutions Dev Compan Analogos de tiazolidindiona para el tratamiento de enfermedad mediada por inflamacion metabolica.
WO2008118327A1 (en) 2007-03-23 2008-10-02 University Of Toledo Conformationally restrained epothilone analogues as anti-leukemic agents
CA2699289C (en) 2007-09-14 2016-01-19 Metabolic Solutions Development Company Thiazolidinedione analogues for the treatment of hypertension
WO2009148195A1 (en) 2008-06-02 2009-12-10 Daebong Ls, Ltd. 5-(4-hydroxybenzyl)thiazolidine-2,4-dione as intermediate for synthesis of thiazolidinedione based compounds and process for preparing the same
WO2011133442A1 (en) 2010-04-19 2011-10-27 Metabolic Solutions Development Company Novel synthesis for thiazolidinedione compounds
CA2796872A1 (en) 2010-04-19 2011-10-27 Metabolic Solutions Development Company, Llc Novel synthesis for thiazolidinedione compounds
ES2609837T3 (es) 2010-08-10 2017-04-24 Octeta Therapeutics, Llc Nueva síntesis de compuestos de tiazolidindiona

Also Published As

Publication number Publication date
JP5851506B2 (ja) 2016-02-03
US8895748B2 (en) 2014-11-25
KR20130097750A (ko) 2013-09-03
CN103153991B (zh) 2016-06-29
RU2013110311A (ru) 2014-09-20
EP2603507B1 (en) 2016-06-29
US8946435B2 (en) 2015-02-03
WO2012021467A1 (en) 2012-02-16
AU2011289627B2 (en) 2015-01-15
KR101857307B1 (ko) 2018-05-11
CA2807815A1 (en) 2012-02-16
CN103153991A (zh) 2013-06-12
MX342289B (es) 2016-09-23
NZ606597A (en) 2014-12-24
AU2011289627A1 (en) 2013-02-21
ES2588769T3 (es) 2016-11-04
JP2013535503A (ja) 2013-09-12
MX2013001475A (es) 2013-04-29
US20130211092A1 (en) 2013-08-15
US20140378687A1 (en) 2014-12-25
CA2807815C (en) 2018-10-02
HUE029488T2 (en) 2017-02-28
RU2594725C2 (ru) 2016-08-20
EP2603507A1 (en) 2013-06-19

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