PL2569314T3 - Skondensowane bicykliczne inhibitory kinazy - Google Patents

Skondensowane bicykliczne inhibitory kinazy

Info

Publication number
PL2569314T3
PL2569314T3 PL11721678T PL11721678T PL2569314T3 PL 2569314 T3 PL2569314 T3 PL 2569314T3 PL 11721678 T PL11721678 T PL 11721678T PL 11721678 T PL11721678 T PL 11721678T PL 2569314 T3 PL2569314 T3 PL 2569314T3
Authority
PL
Poland
Prior art keywords
kinase inhibitors
condensed bicyclic
bicyclic kinase
condensed
inhibitors
Prior art date
Application number
PL11721678T
Other languages
English (en)
Inventor
Mark J. Mulvihill
Arno G. Steinig
Andrew Philip Crew
Meizhong Jin
Andrew Kleinberg
An-Hu Li
Jing Wang
Original Assignee
OSI Pharmaceuticals, LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OSI Pharmaceuticals, LLC filed Critical OSI Pharmaceuticals, LLC
Publication of PL2569314T3 publication Critical patent/PL2569314T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL11721678T 2010-05-14 2011-05-16 Skondensowane bicykliczne inhibitory kinazy PL2569314T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33473410P 2010-05-14 2010-05-14

Publications (1)

Publication Number Publication Date
PL2569314T3 true PL2569314T3 (pl) 2017-02-28

Family

ID=44211949

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11721678T PL2569314T3 (pl) 2010-05-14 2011-05-16 Skondensowane bicykliczne inhibitory kinazy

Country Status (19)

Country Link
US (2) US8445510B2 (pl)
EP (1) EP2569314B1 (pl)
JP (1) JP5820472B2 (pl)
KR (1) KR20130118213A (pl)
CN (1) CN102971316A (pl)
AR (1) AR081039A1 (pl)
AU (1) AU2011252784A1 (pl)
BR (1) BR112012028674A2 (pl)
CA (1) CA2790847A1 (pl)
EA (1) EA201291246A1 (pl)
ES (1) ES2604481T3 (pl)
MX (1) MX2012013206A (pl)
PH (1) PH12012502102A1 (pl)
PL (1) PL2569314T3 (pl)
PT (1) PT2569314T (pl)
SG (1) SG184822A1 (pl)
TW (1) TW201141863A (pl)
WO (1) WO2011143645A1 (pl)
ZA (1) ZA201208489B (pl)

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US20140088114A1 (en) * 2011-05-16 2014-03-27 OSI Pharmaceuticals ,LLC Fused bicyclic kinase inhibitors
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CN105712992B (zh) * 2012-09-29 2018-10-26 上海科州药物研发有限公司 作为cMet抑制剂的化合物及其制备方法和用途
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US20140303121A1 (en) 2013-03-15 2014-10-09 Plexxikon Inc. Heterocyclic compounds and uses thereof
JP6325078B2 (ja) * 2013-03-15 2018-05-16 プレキシコン インコーポレーテッドＰｌｅｘｘｉｋｏｎ Ｉｎｃ． ヘテロ環式化合物およびその使用
CN104513253A (zh) 2013-10-01 2015-04-15 南京波尔泰药业科技有限公司 用于治疗增殖性疾病的大环化合物
CN104628555B (zh) * 2015-01-05 2016-11-30 烟台蓓丰医药科技有限公司 一种药物中间体4-(4-氯苯基)环己基-1-甲酸的合成方法
JOP20190024A1 (ar) 2016-08-26 2019-02-19 Gilead Sciences Inc مركبات بيروليزين بها استبدال واستخداماتها
EP3694855A1 (en) 2017-10-13 2020-08-19 Plexxikon Inc. Solid forms of a compound for modulating kinases
KR102526964B1 (ko) 2018-02-26 2023-04-28 길리애드 사이언시즈, 인코포레이티드 Hbv 복제 억제제로서의 치환된 피롤리진 화합물
CN115667259B (zh) 2020-06-19 2025-06-17 佐藤制药株式会社 抑制h-pgds的稠环化合物

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Also Published As

Publication number Publication date
BR112012028674A2 (pt) 2016-08-16
ES2604481T3 (es) 2017-03-07
CA2790847A1 (en) 2011-11-17
KR20130118213A (ko) 2013-10-29
PT2569314T (pt) 2016-10-25
AR081039A1 (es) 2012-05-30
US8445510B2 (en) 2013-05-21
TW201141863A (en) 2011-12-01
WO2011143645A1 (en) 2011-11-17
JP2013526569A (ja) 2013-06-24
EP2569314A1 (en) 2013-03-20
AU2011252784A1 (en) 2012-09-13
SG184822A1 (en) 2012-12-28
JP5820472B2 (ja) 2015-11-24
US20110281888A1 (en) 2011-11-17
US20130253197A1 (en) 2013-09-26
ZA201208489B (en) 2013-09-25
MX2012013206A (es) 2012-12-17
EA201291246A1 (ru) 2013-04-30
PH12012502102A1 (en) 2013-02-11
CN102971316A (zh) 2013-03-13
EP2569314B1 (en) 2016-09-07

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