PL2567691T3 - Kompozycje wodne obejmujące arbekacynę - Google Patents
Kompozycje wodne obejmujące arbekacynęInfo
- Publication number
- PL2567691T3 PL2567691T3 PL11180927T PL11180927T PL2567691T3 PL 2567691 T3 PL2567691 T3 PL 2567691T3 PL 11180927 T PL11180927 T PL 11180927T PL 11180927 T PL11180927 T PL 11180927T PL 2567691 T3 PL2567691 T3 PL 2567691T3
- Authority
- PL
- Poland
- Prior art keywords
- arbekacin
- aqueous compositions
- compositions
- aqueous
- Prior art date
Links
- MKKYBZZTJQGVCD-XTCKQBCOSA-N arbekacin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O1)O)NC(=O)[C@@H](O)CCN)[C@H]1O[C@H](CN)CC[C@H]1N MKKYBZZTJQGVCD-XTCKQBCOSA-N 0.000 title 1
- 229960005397 arbekacin Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Otolaryngology (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11180927.3A EP2567691B1 (en) | 2011-09-12 | 2011-09-12 | Aqueous compositions comprising arbekacin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2567691T3 true PL2567691T3 (pl) | 2015-05-29 |
Family
ID=46642515
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11180927T PL2567691T3 (pl) | 2011-09-12 | 2011-09-12 | Kompozycje wodne obejmujące arbekacynę |
| PL12745830T PL2755635T3 (pl) | 2011-09-12 | 2012-08-03 | Kompozycje wodne obejmujące arbekacynę |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12745830T PL2755635T3 (pl) | 2011-09-12 | 2012-08-03 | Kompozycje wodne obejmujące arbekacynę |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9511143B2 (pl) |
| EP (2) | EP2567691B1 (pl) |
| JP (1) | JP6072801B2 (pl) |
| KR (1) | KR101944571B1 (pl) |
| CN (1) | CN103826611B (pl) |
| AU (1) | AU2012307661B2 (pl) |
| BR (1) | BR112014005538A2 (pl) |
| CA (1) | CA2844923C (pl) |
| ES (2) | ES2532667T3 (pl) |
| MX (1) | MX357556B (pl) |
| PL (2) | PL2567691T3 (pl) |
| PT (2) | PT2567691E (pl) |
| RU (1) | RU2604767C2 (pl) |
| UA (1) | UA113966C2 (pl) |
| WO (1) | WO2013037566A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2841272C (en) | 2011-07-12 | 2019-01-15 | Alan Bruce Montgomery | Formulations of amikacin and fosfomycin combinations and methods and systems for treatment of ventilator associated pneumonia (vap) and ventilator associated tracheal (vat) bronchitis |
| US9751907B2 (en) | 2013-05-30 | 2017-09-05 | Meiji Seika Pharma Co., Ltd. | Arbekacin derivative, and production and use thereof |
| CN105705138A (zh) | 2013-08-26 | 2016-06-22 | 卡迪斯制药公司 | 具有改进的化学性质的氨基糖苷类物质和磷霉素的组合制剂 |
| EP3285874B1 (en) * | 2015-04-22 | 2021-03-17 | Matinas BioPharma Nanotechnologies, Inc. | Compositions and methods for treating mycobacteria infections and lung disease |
| UA125899C2 (uk) | 2016-05-31 | 2022-07-06 | Поліфор Аг | Бета-шпилькові пептидоміметики, що мають інгібуючу активність відносно еластази, та лікарські форми, що містять їх, у вигляді аерозолю |
| CN110483597A (zh) * | 2019-09-07 | 2019-11-22 | 常州方圆制药有限公司 | 阿贝卡星盐酸盐的假多晶型、其制备方法及其应用 |
| EP4467144A4 (en) * | 2022-01-21 | 2026-01-21 | Senju Usa Inc | AQUEOUS LIQUID FORMULATION |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4029882A (en) * | 1974-03-19 | 1977-06-14 | Schering Corporation | Selective acylation of the C-1 amino group of aminoglycoside antibiotics |
| JPS5651499A (en) | 1979-10-01 | 1981-05-09 | Meiji Seika Kaisha Ltd | Aminoglycoside derivative and its preparation |
| JPS58134099A (ja) | 1982-02-05 | 1983-08-10 | Meiji Seika Kaisha Ltd | アミノ配糖体抗生物質の精製法 |
| JP3215759B2 (ja) * | 1993-09-09 | 2001-10-09 | 財団法人微生物化学研究会 | 耐性菌に有効な５−置換−２″−アミノ−２″−デオキシアルベカシンとその製造法 |
| JP3215732B2 (ja) * | 1992-11-27 | 2001-10-09 | 財団法人微生物化学研究会 | 耐性菌に有効なジベカシン誘導体またはアルベカシン誘導体とそれらの製造法 |
| US5958449A (en) | 1992-12-02 | 1999-09-28 | Nexstar Pharmaceuticals, Inc. | Antibiotic formulation and use for bacterial infections |
| US5508269A (en) | 1994-10-19 | 1996-04-16 | Pathogenesis Corporation | Aminoglycoside formulation for aerosolization |
| JP3213687B2 (ja) * | 1995-10-09 | 2001-10-02 | 財団法人微生物化学研究会 | アルベカシンと（−）−シス−１，２−エポキシプロピルホスホン酸との付加塩およびその製造法、ならびに抗菌剤 |
| JP2001161789A (ja) | 1999-12-07 | 2001-06-19 | Sawai Pharmaceutical Co Ltd | 水性注射剤 |
| EP1273292B1 (en) | 2001-07-02 | 2004-05-26 | CHIESI FARMACEUTICI S.p.A. | Optimised formulation of tobramycin for aerosolization |
| US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| NZ546821A (en) | 2003-10-15 | 2009-04-30 | Pari Pharma Gmbh | Liquid preparation containing tobramycin |
| SI2316419T1 (sl) * | 2004-05-17 | 2012-10-30 | Gilead Sciences Inc | Aerosolna kombinacija fosfomicina/tobramicina za zdravljenje bakterijskih respiratornih infekcij |
| DE102005038619A1 (de) | 2005-08-16 | 2007-02-22 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung mit einer Ampulle für die Bevorratung eines zu vernebelnden Medikaments |
| CA2665764C (en) * | 2006-10-11 | 2015-05-26 | Laboratoires Smb S.A. | Pharmaceutical anti-infective composition for inhalation |
| EP2030644A1 (en) | 2007-08-31 | 2009-03-04 | PARI Pharma GmbH | Aerosols for sinunasal drug delivery |
| DE102007056462B4 (de) | 2007-11-23 | 2011-10-27 | Pari Pharma Gmbh | Einwegampulle für eine Vorrichtung zur Erzeugung von Aerosolen |
| DE102008022987A1 (de) | 2008-05-09 | 2009-11-12 | Pari Pharma Gmbh | Vernebler für Beatmungsmaschinen und Beatmungsmaschine mit einem solchen Vernebler |
| CN101575354B (zh) | 2009-05-26 | 2013-03-13 | 北京化工大学 | 阿贝卡星及其中间体地贝卡星的合成方法 |
| AU2010333173B2 (en) * | 2009-12-14 | 2016-08-25 | Chiesi Farmaceutici S.P.A. | Antibiotic microparticles for inhalation |
| JP5651499B2 (ja) | 2011-03-01 | 2015-01-14 | カヤバ工業株式会社 | フロントフォーク用の姿勢維持具 |
-
2011
- 2011-09-12 PT PT111809273T patent/PT2567691E/pt unknown
- 2011-09-12 PL PL11180927T patent/PL2567691T3/pl unknown
- 2011-09-12 EP EP11180927.3A patent/EP2567691B1/en not_active Not-in-force
- 2011-09-12 ES ES11180927.3T patent/ES2532667T3/es active Active
-
2012
- 2012-08-03 CA CA2844923A patent/CA2844923C/en active Active
- 2012-08-03 ES ES12745830.5T patent/ES2555462T3/es active Active
- 2012-08-03 UA UAA201403851A patent/UA113966C2/uk unknown
- 2012-08-03 JP JP2014530130A patent/JP6072801B2/ja not_active Expired - Fee Related
- 2012-08-03 PL PL12745830T patent/PL2755635T3/pl unknown
- 2012-08-03 US US14/344,487 patent/US9511143B2/en not_active Expired - Fee Related
- 2012-08-03 WO PCT/EP2012/065265 patent/WO2013037566A1/en not_active Ceased
- 2012-08-03 RU RU2014114512/15A patent/RU2604767C2/ru active
- 2012-08-03 BR BR112014005538A patent/BR112014005538A2/pt not_active Application Discontinuation
- 2012-08-03 AU AU2012307661A patent/AU2012307661B2/en not_active Ceased
- 2012-08-03 KR KR1020147009537A patent/KR101944571B1/ko not_active Expired - Fee Related
- 2012-08-03 PT PT127458305T patent/PT2755635E/pt unknown
- 2012-08-03 EP EP12745830.5A patent/EP2755635B1/en active Active
- 2012-08-03 CN CN201280044339.0A patent/CN103826611B/zh not_active Expired - Fee Related
- 2012-08-03 MX MX2014002465A patent/MX357556B/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US9511143B2 (en) | 2016-12-06 |
| RU2014114512A (ru) | 2015-10-27 |
| JP2014526481A (ja) | 2014-10-06 |
| PL2755635T3 (pl) | 2016-03-31 |
| EP2567691A1 (en) | 2013-03-13 |
| KR20140090598A (ko) | 2014-07-17 |
| CN103826611B (zh) | 2016-10-19 |
| KR101944571B1 (ko) | 2019-01-31 |
| AU2012307661B2 (en) | 2017-02-02 |
| CA2844923A1 (en) | 2013-03-21 |
| PT2567691E (pt) | 2015-04-09 |
| ES2555462T3 (es) | 2016-01-04 |
| UA113966C2 (xx) | 2017-04-10 |
| RU2604767C2 (ru) | 2016-12-10 |
| CA2844923C (en) | 2019-04-30 |
| PT2755635E (pt) | 2016-02-10 |
| EP2567691B1 (en) | 2014-12-24 |
| EP2755635B1 (en) | 2015-10-14 |
| AU2012307661A1 (en) | 2014-02-20 |
| WO2013037566A1 (en) | 2013-03-21 |
| MX2014002465A (es) | 2014-08-01 |
| EP2755635A1 (en) | 2014-07-23 |
| US20140343005A1 (en) | 2014-11-20 |
| CN103826611A (zh) | 2014-05-28 |
| JP6072801B2 (ja) | 2017-02-01 |
| BR112014005538A2 (pt) | 2017-03-21 |
| MX357556B (es) | 2018-07-13 |
| ES2532667T3 (es) | 2015-03-30 |
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