PL2553090T3 - Termostabilne warianty fitazy - Google Patents

Termostabilne warianty fitazy

Info

Publication number
PL2553090T3
PL2553090T3 PL11709966T PL11709966T PL2553090T3 PL 2553090 T3 PL2553090 T3 PL 2553090T3 PL 11709966 T PL11709966 T PL 11709966T PL 11709966 T PL11709966 T PL 11709966T PL 2553090 T3 PL2553090 T3 PL 2553090T3
Authority
PL
Poland
Prior art keywords
phytase variants
thermostable phytase
thermostable
variants
phytase
Prior art date
Application number
PL11709966T
Other languages
English (en)
Inventor
Lars Kobberoee Skov
Leonardo De Maria
Tomoko Matsui
Original Assignee
Novozymes A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes A/S filed Critical Novozymes A/S
Publication of PL2553090T3 publication Critical patent/PL2553090T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/195Proteins from microorganisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/14Multiple stages of fermentation; Multiple types of microorganisms or re-use of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/030083-Phytase (3.1.3.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/030264-Phytase (3.1.3.26), i.e. 6-phytase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/030725-Phytase (3.1.3.72)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Husbandry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL11709966T 2010-03-26 2011-03-25 Termostabilne warianty fitazy PL2553090T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10158027 2010-03-26
EP11709966.3A EP2553090B1 (en) 2010-03-26 2011-03-25 Thermostable phytase variants
PCT/EP2011/054639 WO2011117396A2 (en) 2010-03-26 2011-03-25 Thermostable phytase variants

Publications (1)

Publication Number Publication Date
PL2553090T3 true PL2553090T3 (pl) 2019-08-30

Family

ID=44123229

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11709966T PL2553090T3 (pl) 2010-03-26 2011-03-25 Termostabilne warianty fitazy

Country Status (10)

Country Link
US (2) US20130195829A1 (pl)
EP (1) EP2553090B1 (pl)
CN (1) CN102906254A (pl)
AU (1) AU2011231562B2 (pl)
BR (1) BR112012023840B1 (pl)
CA (2) CA2794095C (pl)
DK (1) DK2553090T3 (pl)
ES (1) ES2723050T3 (pl)
PL (1) PL2553090T3 (pl)
WO (1) WO2011117396A2 (pl)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8877478B2 (en) 2006-09-21 2014-11-04 Verenium Corporation Phytases, nucleic acids encoding them and methods for making and using them
GB201102857D0 (en) 2011-02-18 2011-04-06 Danisco Feed additive composition
GB201102865D0 (en) 2011-02-18 2011-04-06 Danisco Feed additive composition
BR112013021017B1 (pt) 2011-02-18 2020-04-07 Dupont Nutrition Biosci Aps composição de aditivo de ração, seu método de preparo, método para preparar uma ração e pré mistura
KR20140057254A (ko) 2011-07-07 2014-05-12 듀폰 뉴트리션 바이오사이언시즈 에이피에스 검정법
GB201213801D0 (en) 2012-08-03 2012-09-12 Dupont Nutrition Biosci Aps Feed additive composition
GB201308828D0 (en) 2013-03-12 2013-07-03 Verenium Corp Phytase
GB201308843D0 (en) 2013-03-14 2013-07-03 Verenium Corp Phytase formulation
EP2799531A1 (de) 2013-05-03 2014-11-05 Clariant Produkte (Deutschland) GmbH Einsatz von Phosphatasen zur enzymatischen Entschleimung von Triglyceriden
BR112015032838A2 (pt) 2013-07-25 2017-11-07 Basf Enzymes Llc fitase
ES2818986T5 (es) 2013-08-09 2024-01-25 Biomadison Inc Ensayo de toxina botulínica con sensibilidad mejorada
CN104450643B (zh) * 2014-12-19 2020-07-28 青岛蔚蓝生物集团有限公司 植酸酶突变体及其应用
TWI616532B (zh) * 2016-02-18 2018-03-01 基酵生物科技股份有限公司 提升耐熱性的植酸酶
TWI607088B (zh) * 2016-02-18 2017-12-01 基酵生物科技股份有限公司 提升耐熱性的植酸酶
TWI615471B (zh) * 2016-02-18 2018-02-21 基酵生物科技股份有限公司 提升耐熱性的植酸酶
TWI591180B (zh) 2016-02-18 2017-07-11 基酵生物科技股份有限公司 提升耐熱性的植酸酶
CN110129299B (zh) * 2016-06-02 2021-08-03 天津科技大学 磷脂酶d及其应用
WO2019156670A1 (en) 2018-02-08 2019-08-15 Danisco Us Inc. Thermally-resistant wax matrix particles for enzyme encapsulation
MX2020011305A (es) 2018-04-26 2021-01-08 Danisco Us Inc Método para aumentar la estabilidad de una fitasa en una composición sólida y una composición granulada que comprende fosfato y fitasa.
US20210207112A1 (en) * 2018-05-30 2021-07-08 Nanjing Bestzyme Bio-Engineering Co., Ltd. Phytase mutant
EP3996519A1 (en) 2019-07-09 2022-05-18 DuPont Nutrition Biosciences ApS Fat coated particulate enzyme compositions
EP4013236A1 (en) 2019-08-16 2022-06-22 DuPont Nutrition Biosciences ApS Compositions for gut health comprising combinations of lactobacillus strains
WO2021046073A1 (en) 2019-09-05 2021-03-11 Dupont Nutrition Biosciences Aps Feed composition
EP4048081A2 (en) 2019-10-21 2022-08-31 DuPont Nutrition Biosciences ApS Compositions for gut health
AU2021217391A1 (en) 2020-02-07 2022-09-01 International N&H Denmark Aps Feed compositions for animal health
PE20231568A1 (es) 2020-08-13 2023-10-04 Novozymes As Variantes de fitasa y polinucleotidos que codifican las mismas
WO2022081947A1 (en) 2020-10-16 2022-04-21 Dupont Nutrition Biosciences Feed compositions for animal health
WO2022169933A2 (en) 2021-02-03 2022-08-11 Dupont Nutrition Biosciences Aps Compositions for gut health
KR20240060703A (ko) 2021-09-27 2024-05-08 인터내셔널 엔&에이치 덴마크 에이피에스 사료 첨가제 조성물 및 이의 사용 방법

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004085638A1 (en) 2003-03-25 2004-10-07 Republic Of National Fisheries Research And Development Institute Phytase produced from citrobacter braakii
GB0422052D0 (en) * 2004-10-04 2004-11-03 Dansico As Enzymes
WO2006038128A2 (en) 2004-10-04 2006-04-13 Danisco A/S Citrobacter freundii phytase and homologues
MX285771B (es) * 2004-10-04 2011-04-07 Novozymes As Polipeptidos que tienen avtividad de fitasa y polinucleotidos queridos mama y papa: codifican los mismos.
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
JP5221516B2 (ja) * 2006-04-04 2013-06-26 ノボザイムス アクティーゼルスカブ フィターゼ変異体
WO2008017066A2 (en) * 2006-08-03 2008-02-07 Cornell Research Foundation, Inc. Phytases with improved thermal stability
AU2008209720C1 (en) * 2007-01-30 2016-06-16 Novozymes A/S Polypeptides having phytase activty and polynucleotides encoding same
CA2681392C (en) * 2007-03-26 2017-08-01 Novozymes A/S Hafnia phytase
WO2009110933A2 (en) * 2007-12-03 2009-09-11 Syngenta Participations Ag Engineering enzymatically susceptible phytases
EP2933329B1 (en) * 2008-09-26 2017-05-17 Novozymes A/S Hafnia phytase variants
FR2947563B1 (fr) * 2009-07-01 2015-08-21 Biomethodes Variants ameliores d'une phytase
US8334124B1 (en) * 2009-09-23 2012-12-18 The United States Of America As Represented By The Secretary Of Agriculture Modified Aspergillus niger phytase
JP2013507939A (ja) * 2009-10-22 2013-03-07 ビーエーエスエフ ソシエタス・ヨーロピア 合成フィターゼ変異体
WO2011117397A1 (en) * 2010-03-26 2011-09-29 Novozymes A/S Thermostable phytase variants
EP2553091B1 (en) * 2010-03-26 2019-05-08 Novozymes A/S Thermostable phytase variants
BR112013021017B1 (pt) * 2011-02-18 2020-04-07 Dupont Nutrition Biosci Aps composição de aditivo de ração, seu método de preparo, método para preparar uma ração e pré mistura
CN103502443B (zh) * 2011-04-21 2016-05-04 巴斯夫欧洲公司 合成的植酸酶变体

Also Published As

Publication number Publication date
CA2794095C (en) 2021-02-16
WO2011117396A3 (en) 2011-11-24
DK2553090T3 (da) 2019-05-13
EP2553090A2 (en) 2013-02-06
AU2011231562A1 (en) 2012-09-27
CA2794095A1 (en) 2011-09-29
CN102906254A (zh) 2013-01-30
ES2723050T3 (es) 2019-08-21
WO2011117396A2 (en) 2011-09-29
CA3105079A1 (en) 2011-09-29
US9611469B2 (en) 2017-04-04
US20130195829A1 (en) 2013-08-01
BR112012023840B1 (pt) 2021-06-22
BR112012023840A2 (pt) 2020-07-28
EP2553090B1 (en) 2019-02-27
AU2011231562B2 (en) 2015-10-22
US20150159149A1 (en) 2015-06-11

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