PL2488551T3 - Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania - Google Patents

Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania

Info

Publication number
PL2488551T3
PL2488551T3 PL10768878T PL10768878T PL2488551T3 PL 2488551 T3 PL2488551 T3 PL 2488551T3 PL 10768878 T PL10768878 T PL 10768878T PL 10768878 T PL10768878 T PL 10768878T PL 2488551 T3 PL2488551 T3 PL 2488551T3
Authority
PL
Poland
Prior art keywords
monoclonal antibodies
progastrin monoclonal
progastrin
antibodies
monoclonal
Prior art date
Application number
PL10768878T
Other languages
English (en)
Polish (pl)
Inventor
Julie Pannequin
Laure Boudier
Dominique Joubert
Frédéric HOLLANDE
Original Assignee
Progastrine Et Cancers S.À R.L.
Institut National De La Santé Et De La Recherche Médicale (Inserm)
Centre National De La Recherche Scientifique (Cnrs)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43086711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2488551(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Progastrine Et Cancers S.À R.L., Institut National De La Santé Et De La Recherche Médicale (Inserm), Centre National De La Recherche Scientifique (Cnrs) filed Critical Progastrine Et Cancers S.À R.L.
Publication of PL2488551T3 publication Critical patent/PL2488551T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • G01N33/57535
    • G01N33/57585
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/595Gastrins; Cholecystokinins [CCK]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL10768878T 2009-10-16 2010-10-15 Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania PL2488551T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25262509P 2009-10-16 2009-10-16
PCT/EP2010/006329 WO2011045080A2 (en) 2009-10-16 2010-10-15 Monoclonal antibodies to progastrin and their uses
EP10768878.0A EP2488551B1 (en) 2009-10-16 2010-10-15 Monoclonal antibodies to progastrin and their uses

Publications (1)

Publication Number Publication Date
PL2488551T3 true PL2488551T3 (pl) 2019-01-31

Family

ID=43086711

Family Applications (2)

Application Number Title Priority Date Filing Date
PL10768878T PL2488551T3 (pl) 2009-10-16 2010-10-15 Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania
PL18185172.6T PL3421493T3 (pl) 2009-10-16 2010-10-15 Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL18185172.6T PL3421493T3 (pl) 2009-10-16 2010-10-15 Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania

Country Status (42)

Country Link
US (7) US9611320B2 (enExample)
EP (2) EP3421493B1 (enExample)
JP (3) JP5985987B2 (enExample)
KR (2) KR20120091221A (enExample)
CN (2) CN102791735B (enExample)
AP (1) AP2012006262A0 (enExample)
AR (1) AR078659A1 (enExample)
AU (1) AU2010306119A1 (enExample)
BR (1) BR112012008818B1 (enExample)
CA (1) CA2777691C (enExample)
CL (1) CL2012000914A1 (enExample)
CR (1) CR20120184A (enExample)
CU (1) CU24196B1 (enExample)
CY (1) CY1120913T1 (enExample)
DK (1) DK2488551T3 (enExample)
EA (2) EA029271B1 (enExample)
EC (1) ECSP12011796A (enExample)
ES (2) ES2973217T3 (enExample)
GE (1) GEP201706604B (enExample)
GT (1) GT201200114A (enExample)
HN (1) HN2012000708A (enExample)
HR (1) HRP20181645T1 (enExample)
IL (2) IL219019B (enExample)
IN (1) IN2012DN03348A (enExample)
LT (1) LT2488551T (enExample)
MA (1) MA33747B1 (enExample)
MX (1) MX351635B (enExample)
NI (1) NI201200054A (enExample)
NZ (2) NZ701709A (enExample)
PE (1) PE20121649A1 (enExample)
PH (1) PH12012500711B1 (enExample)
PL (2) PL2488551T3 (enExample)
PT (1) PT2488551T (enExample)
RS (1) RS57966B1 (enExample)
SG (1) SG10201704933PA (enExample)
SI (1) SI2488551T1 (enExample)
SM (1) SMT201800628T1 (enExample)
TN (1) TN2012000159A1 (enExample)
TW (1) TWI537002B (enExample)
UA (1) UA106771C2 (enExample)
WO (1) WO2011045080A2 (enExample)
ZA (1) ZA201202642B (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8136651B2 (en) * 2007-12-14 2012-03-20 The Procter & Gamble Company Method and apparatus for orienting articles
US7854932B2 (en) 2006-12-19 2010-12-21 The Board Of Regents Of The University Of Texas System Immunogenic compositions comprising progastrin and uses thereof
DK2488551T3 (en) * 2009-10-16 2018-10-08 Progastrine Et Cancers S A R L MONOCLONAL ANTIBODIES AGAINST PROGASTRINE AND APPLICATIONS THEREOF
US8900588B2 (en) * 2010-01-08 2014-12-02 Les Laboratories Servier Methods for treating breast cancer
US8900817B2 (en) * 2010-01-08 2014-12-02 Les Laboratories Servier Progastrin and liver pathologies
EP2550294B1 (en) * 2010-03-24 2019-08-21 Progastrine et Cancers S.à r.l. Prophylaxis of colorectal and gastrointestinal cancer
EP2598531B1 (en) * 2010-07-26 2020-12-30 Progastrine et Cancers S.à r.l. Methods and compositions for liver cancer therapy
US8785603B2 (en) 2011-05-20 2014-07-22 Siemens Healthcare Diagnostics Inc. Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof
EP2715364A1 (en) 2011-06-01 2014-04-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the risk of developing a colonic neoplasia
EP3016683B1 (en) * 2013-07-05 2020-06-24 University of Washington through its Center for Commercialization Soluble mic neutralizing monoclonal antibody for treating cancer
US10023651B2 (en) 2014-04-18 2018-07-17 The Research Foundation For The State University Of New York Humanized anti-TF-antigen antibodies
EP3131581B1 (en) * 2014-04-18 2020-09-23 The Research Foundation of the State University of New York Humanized anti-tf-antigen antibodies
WO2016066671A1 (en) 2014-10-29 2016-05-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for treating resistant cancers using progastrin inhibitors
EP3349768A4 (en) * 2015-09-15 2019-01-23 The Scripps Research Institute ANTIBODIES FOR THE PRODUCTION OF ANTI-INFLAMMATORY MACROPHAGES AND CORRESPONDING USES
US11085924B2 (en) * 2015-12-31 2021-08-10 Syncerus S.À. R.L. Compositions and methods for assessing the risk of cancer occurrence
EP3954998B1 (en) * 2015-12-31 2024-12-25 ECS-Progastrin SA Compositions and methods for detecting and treating gastric cancer
ES2901602T3 (es) * 2015-12-31 2022-03-23 Progastrine Et Cancers S A R L Composiciones y métodos para detectar y tratar el cáncer ovárico
BR112019020414A2 (pt) * 2017-03-30 2020-06-09 Progastrine Et Cancers S.À R.L. composições e métodos para detectar e tratar câncer de próstata usando moléculas de ligação à progastrina
KR102600130B1 (ko) * 2017-03-30 2023-11-08 이씨에스-프로가스트린 에스에이 폐암을 검출하기 위한 조성물 및 방법
PT3720879T (pt) * 2017-12-05 2022-07-13 Progastrine Et Cancers S A R L Terapia de combinação entre anticorpo anti-progastrina e imunoterapia para tratar o cancro
JP7338128B2 (ja) 2017-12-08 2023-09-05 イー、シー、エス、ビオトラッカー、エス、エー、アール、エル 癌診断における放射性標識プロガストリン
TW201940881A (zh) 2018-01-26 2019-10-16 瑞士商Ecs前胃泌激素公司 在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術
KR102699073B1 (ko) * 2018-02-27 2024-08-26 이씨에스-프로가스트린 에스에이 면역치료요법용 생체표지자로서 프로가스트린
TWI793238B (zh) * 2018-12-27 2023-02-21 偉喬生醫股份有限公司 體外檢測生物樣品之胃源性蛋白的方法及套組
US20220372125A1 (en) * 2019-10-02 2022-11-24 Aslan Pharmaceuticals Pte. Ltd. Antigen Specific Binding Domains and Antibody Molecules
CN112062846A (zh) * 2020-04-27 2020-12-11 杭州博茵生物技术有限公司 一种g-17单克隆抗体及其应用
CN115785273B (zh) * 2021-09-10 2023-10-31 东莞市朋志生物科技有限公司 一种抗胃蛋白酶原i的抗体及其应用
CN115724949A (zh) * 2022-12-12 2023-03-03 郑州伊美诺生物技术有限公司 一种鼠源lgG单克隆抗体及其制备方法、应用
CN116143920A (zh) * 2022-12-30 2023-05-23 南京岚煜生物科技有限公司 胃泌素17的单克隆抗体及其细胞株的制备方法和应用
EP4509528A1 (en) * 2023-08-16 2025-02-19 Barrelman Biosciences LLC Monoclonal antibodies against veterinary progastrin-like molecules and their uses
CN117567611B (zh) * 2023-11-22 2024-05-14 艾维可生物科技有限公司 抗成熟型胃泌素17的单克隆抗体及其应用

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634665A (en) 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US5179017A (en) 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4510245A (en) 1982-11-18 1985-04-09 Chiron Corporation Adenovirus promoter system
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4737456A (en) 1985-05-09 1988-04-12 Syntex (U.S.A.) Inc. Reducing interference in ligand-receptor binding assays
US4968615A (en) 1985-12-18 1990-11-06 Ciba-Geigy Corporation Deoxyribonucleic acid segment from a virus
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8720833D0 (en) 1987-09-04 1987-10-14 Celltech Ltd Recombinant dna product
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
DK0463151T3 (da) 1990-01-12 1996-07-01 Cell Genesys Inc Frembringelse af xenogene antistoffer
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
WO1993012227A1 (en) 1991-12-17 1993-06-24 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
IE922437A1 (en) 1991-07-25 1993-01-27 Idec Pharma Corp Recombinant antibodies for human therapy
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
DK1794586T3 (da) * 2004-09-22 2013-05-13 Cancer Advances Inc Monoklonale antistoffer til progastrin
AU2007252986B2 (en) * 2006-05-22 2013-03-21 Centre National De La Recherche Scientifique - Cnrs- Progastrin inhibitors in the treatment of colon cancer
US7854932B2 (en) * 2006-12-19 2010-12-21 The Board Of Regents Of The University Of Texas System Immunogenic compositions comprising progastrin and uses thereof
WO2010037395A2 (en) * 2008-10-01 2010-04-08 Dako Denmark A/S Mhc multimers in cancer vaccines and immune monitoring
DK2488551T3 (en) * 2009-10-16 2018-10-08 Progastrine Et Cancers S A R L MONOCLONAL ANTIBODIES AGAINST PROGASTRINE AND APPLICATIONS THEREOF
EP2550294B1 (en) * 2010-03-24 2019-08-21 Progastrine et Cancers S.à r.l. Prophylaxis of colorectal and gastrointestinal cancer
EP2598531B1 (en) * 2010-07-26 2020-12-30 Progastrine et Cancers S.à r.l. Methods and compositions for liver cancer therapy

Also Published As

Publication number Publication date
KR101640520B1 (ko) 2016-07-19
NZ599971A (en) 2014-12-24
EA201791876A1 (ru) 2018-01-31
CU24196B1 (es) 2016-09-30
KR20120091221A (ko) 2012-08-17
US10377821B2 (en) 2019-08-13
JP2017212992A (ja) 2017-12-07
EA201200597A1 (ru) 2012-12-28
US10385125B2 (en) 2019-08-20
CL2012000914A1 (es) 2012-09-14
US20180022802A1 (en) 2018-01-25
ZA201202642B (en) 2013-06-26
TW201119675A (en) 2011-06-16
US20200002413A1 (en) 2020-01-02
US20170174761A1 (en) 2017-06-22
CU20120060A7 (es) 2013-04-19
BR112012008818A2 (en) 2018-05-22
EP2488551A2 (en) 2012-08-22
BR112012008818B1 (pt) 2021-10-19
JP5985987B2 (ja) 2016-09-06
PH12012500711B1 (en) 2019-04-24
RS57966B1 (sr) 2019-01-31
ECSP12011796A (es) 2012-06-29
JP2015145380A (ja) 2015-08-13
US11299542B2 (en) 2022-04-12
US9611320B2 (en) 2017-04-04
US20170306011A1 (en) 2017-10-26
GT201200114A (es) 2014-08-11
EA029271B1 (ru) 2018-03-30
GEP201706604B (en) 2017-01-25
SG10201704933PA (en) 2017-07-28
US20170306012A1 (en) 2017-10-26
IL219019B (en) 2019-05-30
EP3421493A1 (en) 2019-01-02
MX2012004400A (es) 2012-06-27
US20220195035A1 (en) 2022-06-23
UA106771C2 (uk) 2014-10-10
SI2488551T1 (sl) 2019-01-31
HRP20181645T1 (hr) 2018-12-14
AR078659A1 (es) 2011-11-23
CN102791735B (zh) 2016-05-18
JP6272793B2 (ja) 2018-01-31
EP2488551B1 (en) 2018-07-25
SMT201800628T1 (it) 2019-01-11
ES2973217T3 (es) 2024-06-19
CY1120913T1 (el) 2019-12-11
CA2777691C (en) 2018-02-27
CN102791735A (zh) 2012-11-21
LT2488551T (lt) 2018-10-25
CR20120184A (es) 2012-08-20
AU2010306119A1 (en) 2012-05-03
MA33747B1 (fr) 2012-11-01
PH12012500711A1 (en) 2012-11-12
IL254004B2 (en) 2023-06-01
JP2013507138A (ja) 2013-03-04
ES2690943T3 (es) 2018-11-23
US20110117086A1 (en) 2011-05-19
IL254004A0 (en) 2017-10-31
EP3421493B1 (en) 2024-01-17
PT2488551T (pt) 2018-10-31
US10385124B2 (en) 2019-08-20
MX351635B (es) 2017-10-23
HK1178183A1 (zh) 2013-09-06
DK2488551T3 (en) 2018-10-08
AP2012006262A0 (en) 2012-06-30
TN2012000159A1 (en) 2013-12-12
PL3421493T3 (pl) 2024-04-29
IL219019A0 (en) 2012-06-28
WO2011045080A3 (en) 2011-07-07
US10385126B2 (en) 2019-08-20
CN104628857A (zh) 2015-05-20
EP3421493C0 (en) 2024-01-17
HN2012000708A (es) 2015-06-22
KR20150082672A (ko) 2015-07-15
NZ701709A (en) 2016-06-24
WO2011045080A2 (en) 2011-04-21
IN2012DN03348A (enExample) 2015-10-23
NI201200054A (es) 2012-08-20
CA2777691A1 (en) 2011-04-21
PE20121649A1 (es) 2012-12-08
TWI537002B (zh) 2016-06-11

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