PL2470545T3 - Bezwodne postaci pochodnej pirydyny - Google Patents
Bezwodne postaci pochodnej pirydynyInfo
- Publication number
- PL2470545T3 PL2470545T3 PL10747619T PL10747619T PL2470545T3 PL 2470545 T3 PL2470545 T3 PL 2470545T3 PL 10747619 T PL10747619 T PL 10747619T PL 10747619 T PL10747619 T PL 10747619T PL 2470545 T3 PL2470545 T3 PL 2470545T3
- Authority
- PL
- Poland
- Prior art keywords
- pyridine derivative
- anhydrate forms
- anhydrate
- forms
- pyridine
- Prior art date
Links
- 150000003222 pyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23743509P | 2009-08-27 | 2009-08-27 | |
| EP10747619.4A EP2470545B1 (en) | 2009-08-27 | 2010-08-25 | Anhydrate forms of a pyridine derivative |
| PCT/EP2010/062420 WO2011023733A1 (en) | 2009-08-27 | 2010-08-25 | Anhydrate forms of a pyridine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2470545T3 true PL2470545T3 (pl) | 2014-03-31 |
Family
ID=42790943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10747619T PL2470545T3 (pl) | 2009-08-27 | 2010-08-25 | Bezwodne postaci pochodnej pirydyny |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8796269B2 (en:Method) |
| EP (1) | EP2470545B1 (en:Method) |
| JP (3) | JP2013503134A (en:Method) |
| KR (1) | KR20120056258A (en:Method) |
| CN (1) | CN102639536B (en:Method) |
| AU (1) | AU2010288502B2 (en:Method) |
| BR (1) | BR112012003435A2 (en:Method) |
| CA (1) | CA2772168C (en:Method) |
| DK (1) | DK2470545T3 (en:Method) |
| EA (1) | EA021411B1 (en:Method) |
| ES (1) | ES2440938T3 (en:Method) |
| IL (1) | IL217922A (en:Method) |
| IN (1) | IN2012DN01292A (en:Method) |
| MX (1) | MX2012002369A (en:Method) |
| PL (1) | PL2470545T3 (en:Method) |
| SG (1) | SG178231A1 (en:Method) |
| WO (1) | WO2011023733A1 (en:Method) |
| ZA (1) | ZA201200812B (en:Method) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2470545B1 (en) * | 2009-08-27 | 2013-10-09 | NeRRe Therapeutics Limited | Anhydrate forms of a pyridine derivative |
| EP3915560A1 (en) * | 2014-06-25 | 2021-12-01 | Emory University | Methods of managing conditioned fear with neurokinin receptor antagonists |
| CN114306347A (zh) * | 2015-05-18 | 2022-04-12 | 康堤医疗有限公司 | 用于治疗性激素依赖性疾病的双重nk-1/nk-3受体拮抗剂 |
| KR20190091455A (ko) * | 2016-12-15 | 2019-08-06 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | Nrf2 화합물 |
| SG11202008226YA (en) | 2018-03-14 | 2020-09-29 | Kandy Therapeutics Ltd | Novel pharmaceutical formulation comprising dual nk-1/nk-3 receptor antagonists |
| WO2021030335A1 (en) * | 2019-08-12 | 2021-02-18 | Millendo Therapeutics, Inc. | A stereoisomerically pure nk-3 receptor antagonist and crystalline forms thereof |
| CN118496152A (zh) * | 2019-11-15 | 2024-08-16 | 康堤医疗有限公司 | 制备nt-814的关键中间体6-氯-4-(4-氟-2-甲基苯基)吡啶-3-胺的新化学方法 |
| EP4431512A1 (en) | 2023-03-16 | 2024-09-18 | Bayer Consumer Care AG | Novel dual nk-1/nk-3 receptor antagonists |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1394150E (pt) * | 1999-02-24 | 2011-02-17 | Hoffmann La Roche | Derivados de 4-fenilpiridina e a sua utilização como antagonistas dos receptores de nc-1 |
| GB0203022D0 (en) * | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| AU2004208483B8 (en) * | 2003-01-31 | 2008-04-03 | F. Hoffmann-La Roche Ag | Crystalline modifications of 2-(3,5-bis-trifluoromethyl-phenyl)-N-[6-(1,1-dioxo-1lamda6-thiomorpholin-4-yl)-4-(4-fluoro-2-methyl-phenyl)-pyridin-3-yl]-N-methyl-isobutyramide |
| JP4490421B2 (ja) * | 2003-07-03 | 2010-06-23 | エフ．ホフマン−ラ ロシュ アーゲー | 統合失調症を処置するデュアルｎｋ１／ｎｋ３アンタゴニスト |
| PE20070614A1 (es) | 2005-09-09 | 2007-08-02 | Smithkline Beecham Corp | Derivados biciclicos como antagonistas de nk1/nk3 en el tratamiento de la esquizofrenia |
| CA2692955A1 (en) * | 2007-12-11 | 2009-07-16 | Cipla Ltd | A new method for preparation of zopiclone and its polymorphs |
| GB0814340D0 (en) * | 2008-08-05 | 2008-09-10 | Smithkline Beecham Corp | Anhydrous crystol form fo a pyridine derivative |
| EP2470545B1 (en) * | 2009-08-27 | 2013-10-09 | NeRRe Therapeutics Limited | Anhydrate forms of a pyridine derivative |
| JP6342662B2 (ja) * | 2014-01-29 | 2018-06-13 | 京セラ株式会社 | ドリルおよびそれを用いた切削加工物の製造方法 |
-
2010
- 2010-08-25 EP EP10747619.4A patent/EP2470545B1/en active Active
- 2010-08-25 IN IN1292DEN2012 patent/IN2012DN01292A/en unknown
- 2010-08-25 DK DK10747619.4T patent/DK2470545T3/da active
- 2010-08-25 JP JP2012526048A patent/JP2013503134A/ja active Pending
- 2010-08-25 ES ES10747619.4T patent/ES2440938T3/es active Active
- 2010-08-25 SG SG2012007464A patent/SG178231A1/en unknown
- 2010-08-25 MX MX2012002369A patent/MX2012002369A/es active IP Right Grant
- 2010-08-25 AU AU2010288502A patent/AU2010288502B2/en active Active
- 2010-08-25 CA CA2772168A patent/CA2772168C/en active Active
- 2010-08-25 KR KR1020127004865A patent/KR20120056258A/ko not_active Ceased
- 2010-08-25 WO PCT/EP2010/062420 patent/WO2011023733A1/en active Application Filing
- 2010-08-25 EA EA201270302A patent/EA021411B1/ru not_active IP Right Cessation
- 2010-08-25 BR BR112012003435A patent/BR112012003435A2/pt not_active Application Discontinuation
- 2010-08-25 US US13/389,525 patent/US8796269B2/en active Active
- 2010-08-25 PL PL10747619T patent/PL2470545T3/pl unknown
- 2010-08-25 CN CN201080037918.3A patent/CN102639536B/zh active Active
-
2012
- 2012-02-02 IL IL217922A patent/IL217922A/en active IP Right Grant
- 2012-02-02 ZA ZA2012/00812A patent/ZA201200812B/en unknown
-
2015
- 2015-07-13 JP JP2015139845A patent/JP6404186B2/ja active Active
-
2017
- 2017-06-09 JP JP2017114602A patent/JP2017193564A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010288502B2 (en) | 2013-12-12 |
| WO2011023733A1 (en) | 2011-03-03 |
| CA2772168C (en) | 2019-01-08 |
| EP2470545A1 (en) | 2012-07-04 |
| AU2010288502A1 (en) | 2012-02-23 |
| JP2013503134A (ja) | 2013-01-31 |
| JP2016000739A (ja) | 2016-01-07 |
| SG178231A1 (en) | 2012-03-29 |
| IL217922A0 (en) | 2012-03-29 |
| MX2012002369A (es) | 2012-03-29 |
| US20120157450A1 (en) | 2012-06-21 |
| ZA201200812B (en) | 2013-03-27 |
| CN102639536A (zh) | 2012-08-15 |
| CA2772168A1 (en) | 2011-03-03 |
| IL217922A (en) | 2016-06-30 |
| IN2012DN01292A (en:Method) | 2015-06-05 |
| EA021411B1 (ru) | 2015-06-30 |
| US8796269B2 (en) | 2014-08-05 |
| JP2017193564A (ja) | 2017-10-26 |
| DK2470545T3 (da) | 2014-01-13 |
| EA201270302A1 (ru) | 2012-07-30 |
| JP6404186B2 (ja) | 2018-10-10 |
| EP2470545B1 (en) | 2013-10-09 |
| BR112012003435A2 (pt) | 2016-02-23 |
| CN102639536B (zh) | 2015-03-18 |
| ES2440938T3 (es) | 2014-01-31 |
| KR20120056258A (ko) | 2012-06-01 |
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