PL2155200T3 - Postać krystaliczna pochodnej karbamoilo-cykloheksanu - Google Patents
Postać krystaliczna pochodnej karbamoilo-cykloheksanuInfo
- Publication number
- PL2155200T3 PL2155200T3 PL08755214T PL08755214T PL2155200T3 PL 2155200 T3 PL2155200 T3 PL 2155200T3 PL 08755214 T PL08755214 T PL 08755214T PL 08755214 T PL08755214 T PL 08755214T PL 2155200 T3 PL2155200 T3 PL 2155200T3
- Authority
- PL
- Poland
- Prior art keywords
- carbamoyl
- crystalline form
- cyclohexane derivative
- cyclohexane
- derivative
- Prior art date
Links
- PNZXMIKHJXIPEK-UHFFFAOYSA-N cyclohexanecarboxamide Chemical class NC(=O)C1CCCCC1 PNZXMIKHJXIPEK-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91738307P | 2007-05-11 | 2007-05-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2155200T3 true PL2155200T3 (pl) | 2017-06-30 |
Family
ID=40002604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08755214T PL2155200T3 (pl) | 2007-05-11 | 2008-05-09 | Postać krystaliczna pochodnej karbamoilo-cykloheksanu |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7829569B2 (pl) |
| EP (1) | EP2155200B1 (pl) |
| JP (2) | JP2010526832A (pl) |
| KR (2) | KR20100027137A (pl) |
| CN (1) | CN101801381B (pl) |
| AU (1) | AU2008251520B2 (pl) |
| CA (2) | CA2687078C (pl) |
| CY (1) | CY1118553T1 (pl) |
| DK (1) | DK2155200T3 (pl) |
| EA (1) | EA017732B1 (pl) |
| ES (1) | ES2617671T3 (pl) |
| HK (1) | HK1145148A1 (pl) |
| HR (1) | HRP20170222T1 (pl) |
| HU (1) | HUE033357T2 (pl) |
| LT (1) | LT2155200T (pl) |
| MY (1) | MY148643A (pl) |
| PL (1) | PL2155200T3 (pl) |
| PT (1) | PT2155200T (pl) |
| SI (1) | SI2155200T1 (pl) |
| WO (1) | WO2008141135A1 (pl) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0700353A2 (en) * | 2007-05-18 | 2008-12-29 | Richter Gedeon Nyrt | Metabolites of (thio)carbamoyl-cyclohexane derivatives |
| HUP0700369A2 (en) * | 2007-05-24 | 2009-04-28 | Richter Gedeon Nyrt | Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment in the manufacture of a medicament for the treatment of schizophrenia |
| HUP0700370A2 (en) * | 2007-05-24 | 2009-04-28 | Richter Gedeon Nyrt | Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania |
| US7875610B2 (en) * | 2007-12-03 | 2011-01-25 | Richter Gedeon Nyrt. | Pyrimidinyl-piperazines useful as D3/D2 receptor ligands |
| ATE552002T1 (de) * | 2008-02-21 | 2012-04-15 | Richter Gedeon Nyrt | Feste zubereitung zur oralen verabreichung |
| CN102118970A (zh) | 2008-07-16 | 2011-07-06 | 吉瑞工厂 | 包含多巴胺受体配体的药物制剂 |
| HU230067B1 (hu) | 2008-12-17 | 2015-06-29 | Richter Gedeon Nyrt | Új piperazin só és eljárás előállítására |
| HUP0800766A2 (en) | 2008-12-18 | 2010-11-29 | Richter Gedeon Vegyeszet | Process for the preparation of piperazine derivatives |
| HUP0800765A2 (en) | 2008-12-18 | 2010-11-29 | Richter Gedeon Nyrt | A new process for the preparation of piperazine derivatives and their hydrochloric salts |
| WO2010128959A1 (en) | 2009-05-07 | 2010-11-11 | Halliburton Energy Services, Inc | Device orientation determination |
| WO2012063246A1 (en) * | 2010-11-11 | 2012-05-18 | Mapi Pharma Ltd. | Amorphous form of lurasidone hydrochloride |
| WO2013014665A1 (en) | 2011-07-28 | 2013-01-31 | Mapi Pharma Ltd. | Intermediate compounds and process for the preparation of lurasidone and salts thereof |
| US8912197B2 (en) | 2012-08-20 | 2014-12-16 | Forest Laboratories Holdings Ltd. | Crystalline form of carbamoyl-cyclohexane derivatives |
| CN105218484B (zh) * | 2015-09-14 | 2018-02-23 | 安徽省逸欣铭医药科技有限公司 | 酒石酸卡利拉嗪及其制备方法和医药用途 |
| CN106543105B (zh) * | 2015-09-22 | 2019-10-11 | 江苏恩华药业股份有限公司 | 一种盐酸卡利拉嗪晶型ⅳ及其制备方法 |
| US20170128981A1 (en) * | 2015-11-09 | 2017-05-11 | Delavan Inc | Bulk metallic glass components |
| US11274087B2 (en) | 2016-07-08 | 2022-03-15 | Richter Gedeon Nyrt. | Industrial process for the preparation of cariprazine |
| WO2019016828A1 (en) * | 2017-07-15 | 2019-01-24 | Msn Laboratories Private Limited, R&D Center | NOVEL PROCESSES FOR THE PREPARATION OF TRANS-N- {4- [2- [4- (2,3-DICHLOROPHENYL) PIPERAZIN-1-YL] ETHYL] CYCLOHEXYL} -N ', N'-DIMETHYLUMED HYDROCHLORIDE AND POLYMORPHS THIS ONE |
| WO2020056929A1 (zh) * | 2018-09-21 | 2020-03-26 | 上海诚妙医药科技有限公司 | 卡利拉嗪盐酸盐的新晶型及其制备方法及其用途 |
| US11547707B2 (en) | 2019-04-10 | 2023-01-10 | Richter Gedeon Nyrt. | Carbamoyl cyclohexane derivatives for treating autism spectrum disorder |
| HU231500B1 (hu) | 2019-04-10 | 2024-04-28 | Richter Gedeon Nyrt | Karbamoil-ciklohexán származékok autizmus spektrum betegség kezelésére |
| EP4206191A4 (en) | 2020-08-26 | 2024-09-11 | Shanghai Bocimed Pharmaceutical Co Ltd | PHARMACEUTICALLY ACCEPTABLE SALT OF CARIPRAZINE AND CRYSTALLINE FORM THEREOF, PROCESS FOR PREPARATION THEREOF AND USE THEREOF |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566550B2 (en) * | 2001-06-21 | 2003-05-20 | Pfizer Inc | Substituted aromatic ethers as inhibitors of glycine transport |
| HU227534B1 (en) * | 2003-08-04 | 2011-08-29 | Richter Gedeon Nyrt | (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them |
| DE102004047517A1 (de) * | 2004-09-28 | 2006-03-30 | Merck Patent Gmbh | Neuartige Kristallform von (3-Cyan-1H-indol-7-yl)-[4-(4-fluorphenethyl)-piperazin-1-yl]-methanon, Hydrochlorid |
| GT200600414A (es) * | 2005-09-12 | 2007-09-20 | Sal de glucuranato de compuesto de piperazine | |
| HU230748B1 (hu) * | 2007-05-11 | 2018-02-28 | Richter Gedeon Nyrt | Új piperazin só és előállítási eljárása |
-
2008
- 2008-05-09 WO PCT/US2008/063181 patent/WO2008141135A1/en active Application Filing
- 2008-05-09 US US12/117,972 patent/US7829569B2/en not_active Expired - Fee Related
- 2008-05-09 EA EA200901514A patent/EA017732B1/ru unknown
- 2008-05-09 SI SI200831778A patent/SI2155200T1/sl unknown
- 2008-05-09 KR KR1020097025993A patent/KR20100027137A/ko not_active Application Discontinuation
- 2008-05-09 KR KR20157002948A patent/KR20150023937A/ko not_active Application Discontinuation
- 2008-05-09 EP EP08755214.7A patent/EP2155200B1/en active Active
- 2008-05-09 CA CA2687078A patent/CA2687078C/en active Active
- 2008-05-09 DK DK08755214.7T patent/DK2155200T3/en active
- 2008-05-09 PL PL08755214T patent/PL2155200T3/pl unknown
- 2008-05-09 PT PT87552147T patent/PT2155200T/pt unknown
- 2008-05-09 ES ES08755214.7T patent/ES2617671T3/es active Active
- 2008-05-09 HU HUE08755214A patent/HUE033357T2/en unknown
- 2008-05-09 CA CA2756796A patent/CA2756796C/en active Active
- 2008-05-09 MY MYPI20094772A patent/MY148643A/en unknown
- 2008-05-09 AU AU2008251520A patent/AU2008251520B2/en active Active
- 2008-05-09 LT LTEP08755214.7T patent/LT2155200T/lt unknown
- 2008-05-09 CN CN2008800201802A patent/CN101801381B/zh active Active
- 2008-05-09 JP JP2010507686A patent/JP2010526832A/ja active Pending
-
2010
- 2010-10-05 US US12/898,429 patent/US8609665B2/en active Active
- 2010-12-15 HK HK10111714.0A patent/HK1145148A1/xx unknown
-
2014
- 2014-02-27 JP JP2014036287A patent/JP2014129386A/ja active Pending
-
2017
- 2017-01-31 CY CY20171100137T patent/CY1118553T1/el unknown
- 2017-02-13 HR HRP20170222TT patent/HRP20170222T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20150023937A (ko) | 2015-03-05 |
| CN101801381A (zh) | 2010-08-11 |
| ES2617671T3 (es) | 2017-06-19 |
| CY1118553T1 (el) | 2017-07-12 |
| AU2008251520B2 (en) | 2014-03-06 |
| CA2756796C (en) | 2018-05-22 |
| CN101801381B (zh) | 2013-08-14 |
| JP2014129386A (ja) | 2014-07-10 |
| HUE033357T2 (en) | 2017-11-28 |
| US7829569B2 (en) | 2010-11-09 |
| WO2008141135A1 (en) | 2008-11-20 |
| LT2155200T (lt) | 2017-02-10 |
| US8609665B2 (en) | 2013-12-17 |
| AU2008251520A1 (en) | 2008-11-20 |
| EA017732B1 (ru) | 2013-02-28 |
| CA2687078A1 (en) | 2008-11-20 |
| MY148643A (en) | 2013-05-15 |
| HRP20170222T1 (hr) | 2017-04-07 |
| US20090030007A1 (en) | 2009-01-29 |
| PT2155200T (pt) | 2017-02-21 |
| HK1145148A1 (en) | 2011-04-08 |
| EP2155200A1 (en) | 2010-02-24 |
| EA200901514A1 (ru) | 2010-04-30 |
| SI2155200T1 (sl) | 2017-04-26 |
| US20110028722A1 (en) | 2011-02-03 |
| DK2155200T3 (en) | 2017-03-13 |
| CA2756796A1 (en) | 2008-11-20 |
| EP2155200A4 (en) | 2012-01-04 |
| EP2155200B1 (en) | 2016-12-07 |
| CA2687078C (en) | 2012-04-10 |
| JP2010526832A (ja) | 2010-08-05 |
| KR20100027137A (ko) | 2010-03-10 |
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