PL2379548T3 - Triazolopirydyny jako inhibitory fosfodiesterazy do leczenia chorób skórnych - Google Patents
Triazolopirydyny jako inhibitory fosfodiesterazy do leczenia chorób skórnychInfo
- Publication number
- PL2379548T3 PL2379548T3 PL09795687T PL09795687T PL2379548T3 PL 2379548 T3 PL2379548 T3 PL 2379548T3 PL 09795687 T PL09795687 T PL 09795687T PL 09795687 T PL09795687 T PL 09795687T PL 2379548 T3 PL2379548 T3 PL 2379548T3
- Authority
- PL
- Poland
- Prior art keywords
- triazolopyridines
- treatment
- phosphodiesterase inhibitors
- dermal diseases
- dermal
- Prior art date
Links
- 229940082638 cardiac stimulant phosphodiesterase inhibitors Drugs 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002500 effect on skin Effects 0.000 title 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 title 1
- 150000008523 triazolopyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13944508P | 2008-12-19 | 2008-12-19 | |
| EP09795687.4A EP2379548B1 (en) | 2008-12-19 | 2009-12-18 | Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases |
| PCT/DK2009/000262 WO2010069322A1 (en) | 2008-12-19 | 2009-12-18 | Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2379548T3 true PL2379548T3 (pl) | 2016-08-31 |
Family
ID=41693461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09795687T PL2379548T3 (pl) | 2008-12-19 | 2009-12-18 | Triazolopirydyny jako inhibitory fosfodiesterazy do leczenia chorób skórnych |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8952162B2 (pl) |
| EP (1) | EP2379548B1 (pl) |
| JP (2) | JP5743901B2 (pl) |
| KR (1) | KR20110094355A (pl) |
| CN (1) | CN102317287B (pl) |
| AU (1) | AU2009328752B2 (pl) |
| BR (1) | BRPI0922452A2 (pl) |
| CA (1) | CA2747022A1 (pl) |
| CY (1) | CY1117562T1 (pl) |
| DK (1) | DK2379548T3 (pl) |
| ES (1) | ES2570769T3 (pl) |
| HR (1) | HRP20160488T1 (pl) |
| HU (1) | HUE027770T2 (pl) |
| IL (1) | IL213570A (pl) |
| MX (1) | MX2011006428A (pl) |
| NO (1) | NO20110871A1 (pl) |
| NZ (1) | NZ593595A (pl) |
| PL (1) | PL2379548T3 (pl) |
| RS (1) | RS54752B1 (pl) |
| RU (1) | RU2544011C2 (pl) |
| SG (1) | SG172206A1 (pl) |
| SI (1) | SI2379548T1 (pl) |
| WO (1) | WO2010069322A1 (pl) |
| ZA (1) | ZA201104422B (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010141796A2 (en) | 2009-06-05 | 2010-12-09 | Cephalon, Inc. | PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a] PYRIDINE DERIVATIVES |
| US8283465B2 (en) | 2009-07-17 | 2012-10-09 | Japan Tobacco Inc. | Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor or erythropoietin production-inducing agent |
| EP2343294A1 (en) | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Substituted triazolopyridines |
| MX2012007234A (es) | 2009-12-22 | 2012-07-30 | Leo Pharma As | Nanocristales de monohidrato de calciprotiol. |
| MX2012007225A (es) | 2009-12-22 | 2012-07-30 | Leo Pharma As | Composicion farmaceutica que comprende mezcla de solventes y derivado o analogo de vitamina d. |
| RU2560677C2 (ru) | 2009-12-22 | 2015-08-20 | Лео Фарма А/С | Кожная композиция, включающая аналог витамина d и смесь растворителя и поверхностно-активных веществ |
| ES2711100T3 (es) * | 2011-03-07 | 2019-04-30 | Celgene Corp | Métodos para tratar enfermedades usando compuestos isoindolina |
| MX2014006812A (es) | 2011-12-21 | 2014-10-13 | Leo Pharma As | [1,2,4] triazolopiridinas y su uso como inhibidores de fosfodiesterasa. |
| WO2014083099A1 (en) * | 2012-11-30 | 2014-06-05 | Leo Pharma A/S | A method of inhibiting the expression of il-22 in activated t-cells |
| WO2014206903A1 (en) | 2013-06-25 | 2014-12-31 | Leo Pharma A/S | METHODS FOR THE PREPARATION OF SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIDINES |
| WO2017089347A1 (en) | 2015-11-25 | 2017-06-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas |
| AU2018286964B2 (en) | 2017-06-20 | 2022-04-14 | UNION therapeutics A/S | Methods for the preparation of 1,3-benzodioxole heterocyclic compounds |
| AU2018352983B2 (en) | 2017-10-17 | 2024-02-22 | Conocophillips Company | Low frequency distributed acoustic sensing hydraulic fracture geometry |
| WO2019115776A1 (en) | 2017-12-15 | 2019-06-20 | Leo Pharma A/S | Substituted azetidine dihydrothienopyridines and their use as phosphodiesterase inhibitors |
| JP2021155336A (ja) * | 2018-06-27 | 2021-10-07 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 新規ｐｄｅ４阻害剤 |
| AR114977A1 (es) * | 2018-06-27 | 2020-11-11 | Meiji Seika Pharma Co Ltd | Cristales de derivado de benzoxazol |
| GB202306662D0 (en) | 2023-05-05 | 2023-06-21 | Union Therapeutics As | Dosage regimen |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1000785A1 (en) | 1995-05-19 | 2006-06-30 | Kyowa Hakko Kogyo Co., Ltd | Oxygen-containing heterocyclic compounds |
| AU4967697A (en) | 1996-11-19 | 1998-06-10 | Kyowa Hakko Kogyo Co. Ltd. | Oxygenic heterocyclic compounds |
| US6514989B1 (en) * | 2001-07-20 | 2003-02-04 | Hoffmann-La Roche Inc. | Aromatic and heteroaromatic substituted 1,2,4-triazolo pyridine derivatives |
| US6693116B2 (en) * | 2001-10-08 | 2004-02-17 | Hoffmann-La Roche Inc. | Adenosine receptor ligands |
| US7763617B2 (en) | 2005-03-07 | 2010-07-27 | Kyorin Pharmaceutical Co., Ltd. | Pyrazolopyridine-4-yl pyridazinone derivatives and addition salts thereof, and PDE inhibitors comprising the same derivatives or salts as active ingredient |
| JP2007091597A (ja) * | 2005-09-27 | 2007-04-12 | Kyorin Pharmaceut Co Ltd | ピラゾロピリジン−４−イルピラゾロン誘導体とその付加塩及びそれを有効成分とするホスホジエステラーゼ阻害剤 |
| US20090196284A1 (en) * | 2006-06-28 | 2009-08-06 | Nokia Siemens Networks Gmbh & Co.Kg | Method for Providing an Emergency Call Service for VoIP Subscribers |
| AU2007272009A1 (en) * | 2006-07-12 | 2008-01-17 | Syngenta Limited | Triazolopyridine derivatives as herbicides |
| JP2008024599A (ja) * | 2006-07-18 | 2008-02-07 | Kyorin Pharmaceut Co Ltd | ピリダジノン誘導体、それらを有効成分とするｐｄｅ阻害剤及び医薬 |
| JP2008069144A (ja) * | 2006-08-17 | 2008-03-27 | Kyorin Pharmaceut Co Ltd | ピラゾロン誘導体及びそれらを有効成分とするｐｄｅ阻害剤 |
| JP2010523725A (ja) * | 2007-04-16 | 2010-07-15 | レオ ファーマ アクティーゼルスカブ | 皮膚疾患処置用ホスホジエステラーゼ阻害剤としてのトリアゾロピリジン |
| CA2692248A1 (en) * | 2007-06-19 | 2008-12-24 | Kyorin Pharmaceutical Co., Ltd. | Pyridazinone derivative and pde inhibitor containing the same as active ingredient |
| JPWO2008156102A1 (ja) * | 2007-06-19 | 2010-08-26 | 杏林製薬株式会社 | ピラゾロン誘導体及びそれらを有効成分とするｐｄｅ阻害剤 |
| JP2009040711A (ja) * | 2007-08-08 | 2009-02-26 | Kyorin Pharmaceut Co Ltd | カルボスティリル誘導体及びそれらを有効成分とするｐｄｅ阻害剤 |
| EP2348018A4 (en) | 2008-09-25 | 2012-04-25 | Kyorin Seiyaku Kk | HETEROCYCLIC BIARYL DERIVATIVE AND PDE INHIBITOR CONTAINING ACTIVE SUBSTANCE |
| EP2351748A4 (en) | 2008-10-09 | 2012-03-21 | Kyorin Seiyaku Kk | ISOCHINOLINE DERIVATIVES AND THESE PDE INHIBITORS CONTAINING ACTIVE SUBSTANCE |
-
2009
- 2009-12-18 PL PL09795687T patent/PL2379548T3/pl unknown
- 2009-12-18 AU AU2009328752A patent/AU2009328752B2/en not_active Ceased
- 2009-12-18 KR KR1020117016745A patent/KR20110094355A/ko not_active Ceased
- 2009-12-18 BR BRPI0922452A patent/BRPI0922452A2/pt active Search and Examination
- 2009-12-18 CA CA2747022A patent/CA2747022A1/en not_active Abandoned
- 2009-12-18 SI SI200931410A patent/SI2379548T1/sl unknown
- 2009-12-18 DK DK09795687.4T patent/DK2379548T3/en active
- 2009-12-18 ES ES09795687T patent/ES2570769T3/es active Active
- 2009-12-18 RU RU2011129786/04A patent/RU2544011C2/ru active
- 2009-12-18 US US13/140,505 patent/US8952162B2/en not_active Expired - Fee Related
- 2009-12-18 JP JP2011541089A patent/JP5743901B2/ja not_active Expired - Fee Related
- 2009-12-18 MX MX2011006428A patent/MX2011006428A/es active IP Right Grant
- 2009-12-18 EP EP09795687.4A patent/EP2379548B1/en active Active
- 2009-12-18 SG SG2011044203A patent/SG172206A1/en unknown
- 2009-12-18 RS RS20160308A patent/RS54752B1/sr unknown
- 2009-12-18 HR HRP20160488TT patent/HRP20160488T1/hr unknown
- 2009-12-18 HU HUE09795687A patent/HUE027770T2/en unknown
- 2009-12-18 CN CN200980156864.XA patent/CN102317287B/zh not_active Expired - Fee Related
- 2009-12-18 NZ NZ593595A patent/NZ593595A/xx not_active IP Right Cessation
- 2009-12-18 WO PCT/DK2009/000262 patent/WO2010069322A1/en not_active Ceased
-
2011
- 2011-06-14 ZA ZA2011/04422A patent/ZA201104422B/en unknown
- 2011-06-15 IL IL213570A patent/IL213570A/en not_active IP Right Cessation
- 2011-06-17 NO NO20110871A patent/NO20110871A1/no not_active Application Discontinuation
-
2014
- 2014-12-18 JP JP2014256695A patent/JP2015096535A/ja not_active Withdrawn
-
2016
- 2016-05-06 CY CY20161100373T patent/CY1117562T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20110871A1 (no) | 2011-09-19 |
| JP5743901B2 (ja) | 2015-07-01 |
| RS54752B1 (sr) | 2016-10-31 |
| CY1117562T1 (el) | 2017-04-26 |
| BRPI0922452A2 (pt) | 2015-12-15 |
| CA2747022A1 (en) | 2010-06-24 |
| DK2379548T3 (en) | 2016-05-17 |
| IL213570A0 (en) | 2011-07-31 |
| HUE027770T2 (en) | 2016-11-28 |
| SI2379548T1 (sl) | 2016-06-30 |
| US8952162B2 (en) | 2015-02-10 |
| KR20110094355A (ko) | 2011-08-23 |
| NZ593595A (en) | 2013-07-26 |
| ZA201104422B (en) | 2012-09-26 |
| JP2015096535A (ja) | 2015-05-21 |
| RU2544011C2 (ru) | 2015-03-10 |
| IL213570A (en) | 2015-10-29 |
| AU2009328752B2 (en) | 2015-07-16 |
| EP2379548A1 (en) | 2011-10-26 |
| AU2009328752A1 (en) | 2011-07-07 |
| HK1165791A1 (en) | 2012-10-12 |
| ES2570769T3 (es) | 2016-05-20 |
| CN102317287A (zh) | 2012-01-11 |
| HRP20160488T1 (hr) | 2016-06-17 |
| MX2011006428A (es) | 2011-07-28 |
| CN102317287B (zh) | 2014-10-08 |
| JP2012512192A (ja) | 2012-05-31 |
| SG172206A1 (en) | 2011-07-28 |
| EP2379548B1 (en) | 2016-03-09 |
| US20120028974A1 (en) | 2012-02-02 |
| WO2010069322A1 (en) | 2010-06-24 |
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