PL225479A1 - - Google Patents

Info

Publication number
PL225479A1
PL225479A1 PL22547980A PL22547980A PL225479A1 PL 225479 A1 PL225479 A1 PL 225479A1 PL 22547980 A PL22547980 A PL 22547980A PL 22547980 A PL22547980 A PL 22547980A PL 225479 A1 PL225479 A1 PL 225479A1
Authority
PL
Poland
Application number
PL22547980A
Other versions
PL125597B1 (en
Inventor
Gilbert Rosseels
Pierre Nokin
Original Assignee
Labaz Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz Nv filed Critical Labaz Nv
Publication of PL225479A1 publication Critical patent/PL225479A1/xx
Publication of PL125597B1 publication Critical patent/PL125597B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL1980225479A 1979-07-06 1980-07-04 Process for preparing novel derivatives of indolyzine PL125597B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7923599 1979-07-06

Publications (2)

Publication Number Publication Date
PL225479A1 true PL225479A1 (en:Method) 1981-10-30
PL125597B1 PL125597B1 (en) 1983-05-31

Family

ID=10506339

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1980225479A PL125597B1 (en) 1979-07-06 1980-07-04 Process for preparing novel derivatives of indolyzine

Country Status (24)

Country Link
US (1) US4400387A (en:Method)
EP (1) EP0022762B1 (en:Method)
JP (1) JPS5618979A (en:Method)
AR (1) AR225314A1 (en:Method)
AT (1) AT375078B (en:Method)
AU (1) AU529725B2 (en:Method)
CA (1) CA1153379A (en:Method)
DD (1) DD151940A5 (en:Method)
DE (1) DE3060097D1 (en:Method)
DK (1) DK146962C (en:Method)
ES (1) ES493139A0 (en:Method)
FI (1) FI67217C (en:Method)
GR (1) GR69280B (en:Method)
HU (1) HU182151B (en:Method)
IE (1) IE49994B1 (en:Method)
IN (1) IN151594B (en:Method)
NO (1) NO153496C (en:Method)
NZ (1) NZ193926A (en:Method)
OA (1) OA06563A (en:Method)
PL (1) PL125597B1 (en:Method)
PT (1) PT71424A (en:Method)
SU (1) SU993817A3 (en:Method)
YU (1) YU171880A (en:Method)
ZA (1) ZA803434B (en:Method)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103702A (en) * 1999-05-24 2000-08-15 Board Of Trustees Of The University Of Illinois Use of adenosine deaminase inhibitors to treat systemic inflammatory response syndrome
EP1200102A1 (en) * 1999-07-22 2002-05-02 Supergen, Inc. Methods for treating autoimmune diseases
FR2805460A1 (fr) 2000-02-25 2001-08-31 Oreal Compositions de teinture des fibres keratiniques contenant des derives d'indolizine cationiques et procede de teinture
FR2838123B1 (fr) * 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
JP4048166B2 (ja) * 2002-11-18 2008-02-13 三井製糖株式会社 血糖値上昇抑制剤及び体脂肪蓄積抑制剤並びに食用材料
FR2859997B1 (fr) * 2003-09-18 2006-02-03 Sanofi Synthelabo Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant.
AR051780A1 (es) * 2004-11-29 2007-02-07 Japan Tobacco Inc Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
FR2896247B1 (fr) 2006-01-13 2008-02-29 Sanofi Aventis Sa Composes dimeres agonistes des recepteurs des fgfs (fgfrs), leur procede de preparation et leur application en therapeutique
WO2010113942A1 (ja) * 2009-03-31 2010-10-07 キッセイ薬品工業株式会社 インドリジン誘導体及びその医薬用途
US20100261666A1 (en) * 2009-04-14 2010-10-14 The Board Of Trustees Of The University Of Illinois Compositions and methods for the treatment of myocardial dysfunction associated with sirs or sepsis
ES2549926T3 (es) * 2010-09-29 2015-11-03 Kissei Pharmaceutical Co., Ltd. Derivados (aza)indolizínicos como inhibidores de la xantina-oxidasa
DK3348557T3 (da) * 2015-09-10 2020-07-20 Jiangsu Atom Bioscience And Pharmaceutical Co Ltd Imidazo[1,2-a]pyridiner til behandling eller forebyggelse af hyperurekæmi eller gigt
CN108084186B (zh) 2016-11-16 2021-06-25 江苏新元素医药科技有限公司 Urat1抑制剂及其应用
WO2018090921A1 (zh) 2016-11-16 2018-05-24 江苏新元素医药科技有限公司 Urat1抑制剂及其应用
CN108727267B (zh) * 2017-05-26 2022-05-13 江苏新元素医药科技有限公司 一类urat1抑制剂及其应用
EP3632904B1 (en) * 2017-05-26 2022-04-20 Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd. Urat1 inhibitors for promoting uric acid excretion
KR102750849B1 (ko) * 2018-01-19 2025-01-08 쑤저우 시노벤트 파마슈티칼즈 씨오., 엘티디. 헤테로시클릭 화합물, 제조 방법 및 의약품에서의 이의 용도
CN110283167A (zh) * 2018-11-14 2019-09-27 贵州省中国科学院天然产物化学重点实验室 一种抗心率失常药物布托普洛嗪的制备方法
WO2022169974A1 (en) 2021-02-05 2022-08-11 Nexys Therapeutics, Inc. Inhibitors of urat1 and pharmaceutical uses thereof
WO2023221078A1 (en) * 2022-05-20 2023-11-23 Jiangsu Atom Bioscience And Pharmaceutical Co., Ltd. Solid forms of a compound for treating or preventing hyperuricemia or gout
WO2025237171A1 (zh) * 2024-05-11 2025-11-20 广州市联瑞制药有限公司 嘧啶并五元氮杂环酚类化合物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU430639A1 (ru) 1972-06-05 1978-02-28 Московский Ордена Ленина И Ордена Трудового Красного Знамени Государственный Университет Им.М.В.Ломоносова Способ получени 1-пиридилиндолизинов
FI61030C (fi) * 1976-02-19 1982-05-10 Sanofi Sa Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat
GB1518443A (en) * 1976-02-19 1978-07-19 Labaz Indolizine derivatives and process for preparing the same

Also Published As

Publication number Publication date
IE801349L (en) 1981-01-06
EP0022762B1 (fr) 1981-11-25
EP0022762A1 (fr) 1981-01-21
DK291180A (da) 1981-01-07
DD151940A5 (de) 1981-11-11
IN151594B (en:Method) 1983-06-04
US4400387A (en) 1983-08-23
AR225314A1 (es) 1982-03-15
DK146962C (da) 1984-08-06
ES8105710A1 (es) 1981-06-16
NZ193926A (en) 1984-05-31
OA06563A (fr) 1981-07-31
CA1153379A (en) 1983-09-06
ZA803434B (en) 1981-05-27
ATA354380A (de) 1983-11-15
DK146962B (da) 1984-02-27
AT375078B (de) 1984-06-25
AU529725B2 (en) 1983-06-16
ES493139A0 (es) 1981-06-16
DE3060097D1 (en) 1982-01-28
JPS5618979A (en) 1981-02-23
FI67217B (fi) 1984-10-31
HU182151B (en) 1983-12-28
AU5948780A (en) 1981-01-15
GR69280B (en:Method) 1982-05-13
NO802015L (no) 1981-01-07
FI802165A7 (fi) 1981-01-07
PT71424A (en) 1980-07-01
YU171880A (en) 1983-10-31
NO153496B (no) 1985-12-23
FI67217C (fi) 1985-02-11
SU993817A3 (ru) 1983-01-30
NO153496C (no) 1986-05-14
IE49994B1 (en) 1986-01-22
PL125597B1 (en) 1983-05-31

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