PL2211842T3 - Preparat suchego proszku do inhalacji zawierający glp-1 do stosowania w leczeniu hiperglikemii i cukrzycy w podawaniu płucnym - Google Patents
Preparat suchego proszku do inhalacji zawierający glp-1 do stosowania w leczeniu hiperglikemii i cukrzycy w podawaniu płucnymInfo
- Publication number
- PL2211842T3 PL2211842T3 PL08841194T PL08841194T PL2211842T3 PL 2211842 T3 PL2211842 T3 PL 2211842T3 PL 08841194 T PL08841194 T PL 08841194T PL 08841194 T PL08841194 T PL 08841194T PL 2211842 T3 PL2211842 T3 PL 2211842T3
- Authority
- PL
- Poland
- Prior art keywords
- glp
- hyperglycemia
- diabetes
- treatment
- dry powder
- Prior art date
Links
- 101100337060 Caenorhabditis elegans glp-1 gene Proteins 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 201000001421 hyperglycemia Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000843 powder Substances 0.000 title 1
- 230000002685 pulmonary effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98236807P | 2007-10-24 | 2007-10-24 | |
| US98562007P | 2007-11-05 | 2007-11-05 | |
| US3374008P | 2008-03-04 | 2008-03-04 | |
| US5212708P | 2008-05-09 | 2008-05-09 | |
| EP08841194.7A EP2211842B1 (en) | 2007-10-24 | 2008-10-24 | An inhalable dry powder formulation comprising glp-1 for use in the treatment of hyperglycemia and diabetes by pulmonary administration |
| PCT/US2008/081218 WO2009055740A2 (en) | 2007-10-24 | 2008-10-24 | Method of preventing adverse effects by glp-1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2211842T3 true PL2211842T3 (pl) | 2015-12-31 |
Family
ID=40546046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08841194T PL2211842T3 (pl) | 2007-10-24 | 2008-10-24 | Preparat suchego proszku do inhalacji zawierający glp-1 do stosowania w leczeniu hiperglikemii i cukrzycy w podawaniu płucnym |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US8377869B2 (https=) |
| EP (2) | EP2211842B1 (https=) |
| JP (2) | JP2011500850A (https=) |
| KR (2) | KR101736535B1 (https=) |
| CN (1) | CN101969927A (https=) |
| AU (2) | AU2008316634B2 (https=) |
| BR (1) | BRPI0818872A2 (https=) |
| CA (1) | CA2703338A1 (https=) |
| DK (1) | DK2211842T3 (https=) |
| ES (1) | ES2547529T3 (https=) |
| HU (1) | HUE025485T2 (https=) |
| MX (1) | MX2010004510A (https=) |
| PL (1) | PL2211842T3 (https=) |
| RU (2) | RU2474415C2 (https=) |
| WO (1) | WO2009055740A2 (https=) |
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| US9078866B2 (en) * | 2003-08-01 | 2015-07-14 | Mannkind Corporation | Method for treating hyperglycemia with GLP-1 |
| US8921311B2 (en) | 2003-08-01 | 2014-12-30 | Mannkind Corporation | Method for treating hyperglycemia |
| PL1786784T3 (pl) | 2004-08-20 | 2011-04-29 | Mannkind Corp | Kataliza syntezy diketopiperazyn |
| KR101644250B1 (ko) | 2004-08-23 | 2016-07-29 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| CN104324362B (zh) | 2005-09-14 | 2018-04-24 | 曼金德公司 | 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法 |
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| JP2011500850A (ja) | 2007-10-24 | 2011-01-06 | マンカインド コーポレイション | Glp−1による副作用を防止する方法 |
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| ES2929343T3 (es) | 2008-06-13 | 2022-11-28 | Mannkind Corp | Inhalador de polvo seco accionado por aspiración para la administración de fármacos |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| KR101628410B1 (ko) | 2008-06-20 | 2016-06-08 | 맨카인드 코포레이션 | 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법 |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
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| CN104721825B (zh) * | 2009-06-12 | 2019-04-12 | 曼金德公司 | 具有确定比表面积的二酮哌嗪颗粒 |
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| EP2496253B1 (en) * | 2009-11-02 | 2019-01-09 | MannKind Corporation | Apparatus and method for cryogranulating a pharmaceutical composition |
| AU2015203301B2 (en) * | 2009-11-02 | 2017-05-25 | Mannkind Corporation | Reactor for producing pharmaceutical particles in a precipitation process |
| WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| IL223742A (en) | 2010-06-21 | 2016-06-30 | Mannkind Corp | A dry powder inhaler and preparation for it |
| MX340112B (es) * | 2010-11-09 | 2016-06-27 | Mannkind Corp | Composicion que comprende un agonista de receptor de serotonina y una dicetopiperazina para el tratamiento de migrañas. |
| AU2012236150B2 (en) | 2011-04-01 | 2016-03-31 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
| CN104619369B (zh) | 2012-07-12 | 2018-01-30 | 曼金德公司 | 干粉药物输送系统和方法 |
| AU2013308693A1 (en) * | 2012-08-29 | 2015-03-12 | Mannkind Corporation | Method and composition for treating hyperglycemia |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
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| AU2013366692B2 (en) | 2012-12-21 | 2017-11-23 | Sanofi | Dual GLP1/GIP or trigonal GLP1/GIP/Glucagon agonists |
| AU2014228415B2 (en) | 2013-03-15 | 2018-08-09 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
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| KR102891823B1 (ko) | 2023-06-30 | 2025-12-01 | 주식회사 휴온스랩 | GLP (Glucagon Like Peptide) 유사체를 유효성분으로 포함하는 비만 예방 또는 치료용 약학적 조성물 |
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-
2008
- 2008-10-24 JP JP2010531298A patent/JP2011500850A/ja active Pending
- 2008-10-24 RU RU2010120666/15A patent/RU2474415C2/ru not_active IP Right Cessation
- 2008-10-24 CA CA2703338A patent/CA2703338A1/en not_active Abandoned
- 2008-10-24 PL PL08841194T patent/PL2211842T3/pl unknown
- 2008-10-24 MX MX2010004510A patent/MX2010004510A/es active IP Right Grant
- 2008-10-24 KR KR1020137027725A patent/KR101736535B1/ko not_active Expired - Fee Related
- 2008-10-24 US US12/258,340 patent/US8377869B2/en active Active
- 2008-10-24 AU AU2008316634A patent/AU2008316634B2/en not_active Ceased
- 2008-10-24 HU HUE08841194A patent/HUE025485T2/en unknown
- 2008-10-24 BR BRPI0818872 patent/BRPI0818872A2/pt not_active IP Right Cessation
- 2008-10-24 KR KR1020107011096A patent/KR101736502B1/ko not_active Expired - Fee Related
- 2008-10-24 WO PCT/US2008/081218 patent/WO2009055740A2/en not_active Ceased
- 2008-10-24 EP EP08841194.7A patent/EP2211842B1/en not_active Not-in-force
- 2008-10-24 CN CN2008801226703A patent/CN101969927A/zh active Pending
- 2008-10-24 DK DK08841194.7T patent/DK2211842T3/en active
- 2008-10-24 ES ES08841194.7T patent/ES2547529T3/es active Active
- 2008-10-24 EP EP15178836.1A patent/EP2954893A1/en not_active Withdrawn
-
2012
- 2012-10-30 RU RU2012146344/15A patent/RU2012146344A/ru not_active Application Discontinuation
-
2013
- 2013-01-02 US US13/732,911 patent/US20130125886A1/en not_active Abandoned
-
2014
- 2014-05-20 AU AU2014202731A patent/AU2014202731A1/en not_active Abandoned
- 2014-09-18 JP JP2014190113A patent/JP2015013892A/ja active Pending
-
2020
- 2020-01-14 US US16/742,193 patent/US20200147219A1/en not_active Abandoned
-
2022
- 2022-08-15 US US17/887,856 patent/US20220387593A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US8377869B2 (en) | 2013-02-19 |
| DK2211842T3 (en) | 2015-09-21 |
| JP2011500850A (ja) | 2011-01-06 |
| BRPI0818872A2 (pt) | 2015-05-05 |
| RU2474415C2 (ru) | 2013-02-10 |
| US20220387593A1 (en) | 2022-12-08 |
| WO2009055740A3 (en) | 2009-06-11 |
| HUE025485T2 (en) | 2016-02-29 |
| RU2010120666A (ru) | 2011-11-27 |
| US20090110647A1 (en) | 2009-04-30 |
| KR20100093055A (ko) | 2010-08-24 |
| AU2008316634A1 (en) | 2009-04-30 |
| RU2012146344A (ru) | 2014-05-10 |
| EP2211842A2 (en) | 2010-08-04 |
| ES2547529T3 (es) | 2015-10-07 |
| US20200147219A1 (en) | 2020-05-14 |
| KR101736535B1 (ko) | 2017-05-16 |
| EP2954893A1 (en) | 2015-12-16 |
| EP2211842B1 (en) | 2015-08-12 |
| CA2703338A1 (en) | 2009-04-30 |
| AU2014202731A1 (en) | 2014-06-12 |
| KR20130123467A (ko) | 2013-11-12 |
| US20130125886A1 (en) | 2013-05-23 |
| MX2010004510A (es) | 2010-07-02 |
| KR101736502B1 (ko) | 2017-05-16 |
| AU2008316634B2 (en) | 2014-02-27 |
| WO2009055740A2 (en) | 2009-04-30 |
| JP2015013892A (ja) | 2015-01-22 |
| CN101969927A (zh) | 2011-02-09 |
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