PL2100898T3 - Sposób zatężania polipeptydu - Google Patents

Sposób zatężania polipeptydu

Info

Publication number
PL2100898T3
PL2100898T3 PL08166902T PL08166902T PL2100898T3 PL 2100898 T3 PL2100898 T3 PL 2100898T3 PL 08166902 T PL08166902 T PL 08166902T PL 08166902 T PL08166902 T PL 08166902T PL 2100898 T3 PL2100898 T3 PL 2100898T3
Authority
PL
Poland
Prior art keywords
polypeptide
concentration
Prior art date
Application number
PL08166902T
Other languages
English (en)
Inventor
Stefan Nilsson
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of PL2100898T3 publication Critical patent/PL2100898T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1085Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y205/00Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01061Hydroxymethylbilane synthase (2.5.1.61)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/06Sulfuric ester hydrolases (3.1.6)
    • C12Y301/06001Arylsulfatase (3.1.6.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024Alpha-mannosidase (3.2.1.24)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01046Galactosylceramidase (3.2.1.46)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/06Sulfuric ester hydrolases (3.1.6)
    • C12Y301/06008Cerebroside-sulfatase (3.1.6.8)
PL08166902T 2006-04-04 2007-04-04 Sposób zatężania polipeptydu PL2100898T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200600488 2006-04-04
DKPA200600922 2006-07-05
EP07711305.8A EP2004672B1 (en) 2006-04-04 2007-04-04 A process for concentration of a polypeptide
PCT/DK2007/000177 WO2007112757A2 (en) 2006-04-04 2007-04-04 A process for concentration of a polypeptide
EP08166902.0A EP2100898B1 (en) 2006-04-04 2007-04-04 A process for concentration of a polypeptide

Publications (1)

Publication Number Publication Date
PL2100898T3 true PL2100898T3 (pl) 2019-11-29

Family

ID=38472949

Family Applications (3)

Application Number Title Priority Date Filing Date
PL13167428.5T PL2631242T3 (pl) 2006-04-04 2007-04-04 Sposób zatężania polipeptydu
PL08166902T PL2100898T3 (pl) 2006-04-04 2007-04-04 Sposób zatężania polipeptydu
PL13167427T PL2628746T3 (pl) 2006-04-04 2007-04-04 Sposób zatężania polipeptydu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL13167428.5T PL2631242T3 (pl) 2006-04-04 2007-04-04 Sposób zatężania polipeptydu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL13167427T PL2628746T3 (pl) 2006-04-04 2007-04-04 Sposób zatężania polipeptydu

Country Status (20)

Country Link
US (6) US20090246187A1 (pl)
EP (4) EP2628746B1 (pl)
JP (6) JP2009532394A (pl)
KR (3) KR20150103339A (pl)
CN (1) CN105233276A (pl)
AU (2) AU2007234195B2 (pl)
BR (1) BRPI0709737A2 (pl)
CA (3) CA2644642C (pl)
DK (1) DK2628746T3 (pl)
ES (3) ES2744499T3 (pl)
HU (1) HUE042402T2 (pl)
IL (4) IL194267A (pl)
MX (1) MX2008012748A (pl)
NO (3) NO347673B1 (pl)
NZ (7) NZ623123A (pl)
PL (3) PL2631242T3 (pl)
PT (1) PT2628746T (pl)
SI (1) SI2628746T1 (pl)
WO (1) WO2007112757A2 (pl)
ZA (2) ZA200805346B (pl)

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US8536315B2 (en) 2004-01-30 2013-09-17 Shire Pharmaceuticals Ireland Limited Production and purification of recombinant arylsulftase
KR20150103339A (ko) 2006-04-04 2015-09-09 샤이어 파마슈티칼스 아일랜드 리미티드 폴리펩타이드의 농축 방법
AU2011220163B2 (en) * 2010-02-24 2015-05-28 Chiesi Farmaceutici S.P.A. Process for production and purification of recombinant lysosomal alpha-mannosidase
KR102537084B1 (ko) * 2010-06-25 2023-05-26 샤이어 휴먼 지네틱 테라피즈 인크. 아릴설파타제 a의 cns 전달을 위한 방법들 및 조성물들
HUE031036T2 (en) 2010-06-25 2017-06-28 Shire Human Genetic Therapies Therapeutic drug delivery to the central nervous system
US9320711B2 (en) 2010-06-25 2016-04-26 Shire Human Genetic Therapies, Inc. Methods and compositions for CNS delivery of heparan N-sulfatase
WO2011163648A1 (en) 2010-06-25 2011-12-29 Shire Human Genetic Therapies, Inc. Cns delivery of therapeutic agents
ES2625511T3 (es) 2011-07-08 2017-07-19 Shire Human Genetic Therapies, Inc. Métodos para la purificación de arylsulfatasa A
EP2793922B1 (en) 2011-12-23 2019-10-30 Shire Human Genetic Therapies, Inc. Stable formulations for cns delivery of arylsulfatase a
AU2013347260B2 (en) * 2012-11-13 2016-07-28 Chiesi Farmaceutici S.P.A. Purification of recombinant human galactocerebroside beta-galactosidase (rhGALC)
AU2013357812B2 (en) * 2012-12-11 2019-10-10 Centogene Gmbh Method for the diagnosis of metachromatic leukodystrophy
WO2014110246A1 (en) 2013-01-09 2014-07-17 Shire Human Genetic Therapies, Inc. Methods for purification of arylsulfatase a
TWI745671B (zh) 2013-03-15 2021-11-11 美商百歐維拉提夫治療公司 因子ix多肽調配物
CA2943034C (en) 2014-03-24 2022-06-14 Biogen Ma Inc. Lyophilized factor ix formulations
JP6957738B2 (ja) * 2017-08-31 2021-11-02 グリーン・クロス・コーポレイションGreen Cross Corp. スルファターゼタンパク質を精製する方法
KR102290596B1 (ko) * 2020-09-10 2021-08-19 주식회사 파이안바이오테크놀로지 분리된 미토콘드리아를 포함하는 주사용 조성물 및 이의 용도

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WO1999037325A2 (en) 1998-01-27 1999-07-29 Hemebiotech A/S Method for treating acute intermittent porphyria (aip) and other porphyric diseases
RU2197500C2 (ru) * 1998-06-09 2003-01-27 Статенс Серум Институт Способ получения иммуноглобулинов для внутривенного введения и другие иммуноглобулиновые продукты
US6281336B1 (en) * 1998-06-09 2001-08-28 Statens Serum Institut Process for producing immunoglobulins for intravenous administration and other immunoglobulin products
US6537777B1 (en) 1998-07-27 2003-03-25 Hemebiotech A/S Human porphobilinogen deaminase sequences
AUPQ026799A0 (en) * 1999-05-10 1999-06-03 Csl Limited Method of increasing protein stability by removing immunoglobulin aggregates
JP2003505057A (ja) * 1999-07-27 2003-02-12 ヘム−バイオテック エイ/エス rhPBGDの製造及び急性間欠性ポルフィリン症(AIP)及び他のポルフィリン症の患者を処置するための新規な治療方法
US6812339B1 (en) * 2000-09-08 2004-11-02 Applera Corporation Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
CA2429210A1 (en) 2000-11-15 2002-05-23 Jason C. Goodrick Expression system for recombinant proteins
WO2002098455A2 (en) * 2001-06-07 2002-12-12 Hemebiotech A/S Production of recombinant human arylsulfatase a
WO2002099092A2 (en) 2001-06-07 2002-12-12 Hemebiotech A/S Production of recombinant human lysosomal alpha-mannosidase
EP1402014A1 (en) 2001-06-29 2004-03-31 Hemebiotech A/S A process for purification of recombinant porphobilinogen deaminase
US7232670B2 (en) * 2001-09-28 2007-06-19 St. Jude Children's Research Hospital Targeting proteins to cells expressing mannose receptors via expression in insect cells
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US8536315B2 (en) * 2004-01-30 2013-09-17 Shire Pharmaceuticals Ireland Limited Production and purification of recombinant arylsulftase
SI1740204T1 (en) 2004-04-01 2018-07-31 Chiesi Farmaceutici S.P.A. MEDICAL APPLICATION OF ALFA-MANOSIDES
US20060051347A1 (en) * 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
KR20150103339A (ko) * 2006-04-04 2015-09-09 샤이어 파마슈티칼스 아일랜드 리미티드 폴리펩타이드의 농축 방법

Also Published As

Publication number Publication date
EP2631242B1 (en) 2022-08-03
MX2008012748A (es) 2009-01-07
US8809055B2 (en) 2014-08-19
SI2628746T1 (sl) 2019-04-30
ZA200809540B (en) 2019-09-25
CA2882501C (en) 2021-09-07
EP2628746A3 (en) 2014-03-19
EP2100898B1 (en) 2019-06-19
NZ597548A (en) 2013-08-30
IL194267A0 (en) 2011-08-01
NO20084776L (no) 2008-10-31
US20160193304A1 (en) 2016-07-07
NZ588903A (en) 2012-08-31
NZ582045A (en) 2011-07-29
EP2631242A3 (en) 2013-10-02
ES2713488T3 (es) 2019-05-22
HUE042402T2 (hu) 2019-06-28
IL241654B (en) 2019-02-28
NO20211305A1 (no) 2008-10-31
NO347673B1 (no) 2024-02-19
US20140314735A1 (en) 2014-10-23
ZA200805346B (en) 2018-11-28
AU2008229659B2 (en) 2013-01-31
NZ607595A (en) 2014-10-31
NO20082510L (no) 2008-10-31
AU2007234195B2 (en) 2013-02-07
EP2628746A2 (en) 2013-08-21
US20170202927A1 (en) 2017-07-20
EP2100898A1 (en) 2009-09-16
ES2744499T3 (es) 2020-02-25
PT2628746T (pt) 2019-04-23
IL194267A (en) 2015-10-29
EP2004672A2 (en) 2008-12-24
KR20150103339A (ko) 2015-09-09
KR20090018894A (ko) 2009-02-24
JP2009532394A (ja) 2009-09-10
CA2644642A1 (en) 2007-10-11
US20180289777A1 (en) 2018-10-11
KR101504969B1 (ko) 2015-03-24
NO346368B1 (no) 2022-06-27
IL211905A0 (en) 2011-05-31
EP2004672B1 (en) 2015-08-19
ES2928096T3 (es) 2022-11-15
JP2014058521A (ja) 2014-04-03
NZ623123A (en) 2015-04-24
JP2016104000A (ja) 2016-06-09
CA2644642C (en) 2016-01-26
US20120076767A1 (en) 2012-03-29
IL235982A0 (en) 2015-01-29
IL241654A0 (en) 2015-11-30
AU2008229659A1 (en) 2008-10-23
KR20140057678A (ko) 2014-05-13
JP2013236633A (ja) 2013-11-28
JP5878152B2 (ja) 2016-03-08
NZ571610A (en) 2011-07-29
WO2007112757A3 (en) 2008-02-28
JP2009273469A (ja) 2009-11-26
CN105233276A (zh) 2016-01-13
PL2631242T3 (pl) 2023-03-20
US20090246187A1 (en) 2009-10-01
EP2628746B1 (en) 2019-01-09
JP2014051503A (ja) 2014-03-20
CA2632528A1 (en) 2007-10-11
BRPI0709737A2 (pt) 2011-07-26
WO2007112757A2 (en) 2007-10-11
NZ568728A (en) 2011-09-30
US9713634B2 (en) 2017-07-25
JP5384232B2 (ja) 2014-01-08
EP2631242A2 (en) 2013-08-28
AU2007234195A1 (en) 2007-10-11
PL2628746T3 (pl) 2019-07-31
DK2628746T3 (en) 2019-04-01
CA2882501A1 (en) 2007-10-11
CA2632528C (en) 2022-07-12

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