PL2068938T3 - Optymalizacja leczenia białaczki z chromosomem Philadelphia imatinibem będącym inhibitorem kinazy tyrozynowej AbI - Google Patents
Optymalizacja leczenia białaczki z chromosomem Philadelphia imatinibem będącym inhibitorem kinazy tyrozynowej AbIInfo
- Publication number
- PL2068938T3 PL2068938T3 PL07842842T PL07842842T PL2068938T3 PL 2068938 T3 PL2068938 T3 PL 2068938T3 PL 07842842 T PL07842842 T PL 07842842T PL 07842842 T PL07842842 T PL 07842842T PL 2068938 T3 PL2068938 T3 PL 2068938T3
- Authority
- PL
- Poland
- Prior art keywords
- leukemia
- tyrosine kinase
- abl tyrosine
- cmin
- kinase inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Ecology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82662206P | 2006-09-22 | 2006-09-22 | |
US82827806P | 2006-10-05 | 2006-10-05 | |
PCT/US2007/078978 WO2008036792A2 (en) | 2006-09-22 | 2007-09-20 | Method of optimizing the treatment of philadelphia-positive leukemia with abl tyrosine kinase inhibitors |
EP07842842A EP2068938B1 (en) | 2006-09-22 | 2007-09-20 | Optimization of the treatment of philadelphia-positive leukemia with abl tyrosine kinase inhibitor imatinib |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2068938T3 true PL2068938T3 (pl) | 2011-06-30 |
Family
ID=39092883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL07842842T PL2068938T3 (pl) | 2006-09-22 | 2007-09-20 | Optymalizacja leczenia białaczki z chromosomem Philadelphia imatinibem będącym inhibitorem kinazy tyrozynowej AbI |
Country Status (25)
Country | Link |
---|---|
US (2) | US20090281113A1 (pl) |
EP (2) | EP2251042A3 (pl) |
JP (1) | JP5735742B2 (pl) |
KR (1) | KR20090065512A (pl) |
AT (1) | ATE495761T1 (pl) |
AU (1) | AU2007299764B2 (pl) |
BR (1) | BRPI0717099A2 (pl) |
CA (1) | CA2662977A1 (pl) |
CL (1) | CL2007002725A1 (pl) |
CY (1) | CY1111356T1 (pl) |
DE (1) | DE602007012122D1 (pl) |
DK (1) | DK2068938T3 (pl) |
HK (1) | HK1133194A1 (pl) |
HR (1) | HRP20110250T1 (pl) |
IL (1) | IL197296A (pl) |
MA (1) | MA30786B1 (pl) |
MX (1) | MX2009003082A (pl) |
NO (1) | NO20091490L (pl) |
NZ (1) | NZ575113A (pl) |
PL (1) | PL2068938T3 (pl) |
PT (1) | PT2068938E (pl) |
TN (1) | TN2009000094A1 (pl) |
TW (1) | TWI398251B (pl) |
WO (1) | WO2008036792A2 (pl) |
ZA (1) | ZA200901220B (pl) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101579993B1 (ko) | 2008-01-23 | 2015-12-23 | 노파르티스 아게 | 이마티닙을 이용한 티로신 키나제 수용체 kit에 의해 매개되는 증식성 질환의 치료를 최적화하는 방법 |
EP2370078A1 (en) | 2008-12-01 | 2011-10-05 | Novartis AG | Method of optimizing the treatment of philadelphia-positive leukemia with imatinib mesylate |
US20110046919A1 (en) | 2009-03-02 | 2011-02-24 | Juliesta Elaine Sylvester | Method for accurate measurement of enzyme activities |
FR2943418A1 (fr) * | 2009-03-17 | 2010-09-24 | Centre Nat Rech Scient | Procedes de mesure de la quantite intracellulaire de molecules d'interet intrinsequement fluorescentes par cytometrie en flux et leurs applications |
EP3072964A1 (en) * | 2013-11-22 | 2016-09-28 | National Center For Child Health And Development | Novel chimera gene atf7ip-pdgfrb for acute lymphoblastic leukemia |
WO2017007547A1 (en) | 2015-07-07 | 2017-01-12 | Codexis, Inc. | Novel p450-bm3 variants with improved activity |
IT201900008808A1 (it) | 2019-06-13 | 2020-12-13 | Univ Ca Foscari | Metodo per la determinazione della concentrazione di 4-[(4-metil-1-piperazinil)metil]-n-(4-metil-3-{[4-(3-piridinil)-2-pirimidinil]-ammino}fenil)benzammide(imatinib) in campioni di plasma |
CN114994213A (zh) * | 2022-06-28 | 2022-09-02 | 北京赛诺浦生物技术有限公司 | 一种测定人血浆中抗肿瘤药物酪氨酸激酶抑制血药浓度的试剂盒及测定方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5521184A (en) | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
CO4940418A1 (es) | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
ES2391550T3 (es) | 1999-04-15 | 2012-11-27 | Bristol-Myers Squibb Company | Inhibidores cíclicos de la proteína tirosina quinasa |
GB0202873D0 (en) | 2002-02-07 | 2002-03-27 | Novartis Ag | Organic compounds |
JP2005522221A (ja) * | 2002-04-17 | 2005-07-28 | ノバルティス アクチエンゲゼルシャフト | チロシンキナーゼ阻害剤に対する患者応答性の予測方法 |
GB0209265D0 (en) | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
GB0215676D0 (en) | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
GB0222514D0 (en) | 2002-09-27 | 2002-11-06 | Novartis Ag | Organic compounds |
MXPA06014247A (es) | 2004-06-10 | 2007-03-12 | Irm Llc | Compuestos y composiciones como inhibidores de la proteina quinasa. |
GB0421525D0 (en) | 2004-09-28 | 2004-10-27 | Novartis Ag | Inhibitors of protein kineses |
MY148074A (en) | 2005-05-10 | 2013-02-28 | Novartis Ag | Pharmaceutical compositions comprising imatinib and a release retardant |
-
2007
- 2007-09-20 DE DE602007012122T patent/DE602007012122D1/de active Active
- 2007-09-20 AU AU2007299764A patent/AU2007299764B2/en not_active Ceased
- 2007-09-20 MX MX2009003082A patent/MX2009003082A/es active IP Right Grant
- 2007-09-20 AT AT07842842T patent/ATE495761T1/de active
- 2007-09-20 NZ NZ575113A patent/NZ575113A/en not_active IP Right Cessation
- 2007-09-20 WO PCT/US2007/078978 patent/WO2008036792A2/en active Application Filing
- 2007-09-20 US US12/442,126 patent/US20090281113A1/en not_active Abandoned
- 2007-09-20 CA CA002662977A patent/CA2662977A1/en not_active Abandoned
- 2007-09-20 PL PL07842842T patent/PL2068938T3/pl unknown
- 2007-09-20 EP EP10171365A patent/EP2251042A3/en not_active Withdrawn
- 2007-09-20 DK DK07842842.2T patent/DK2068938T3/da active
- 2007-09-20 EP EP07842842A patent/EP2068938B1/en active Active
- 2007-09-20 PT PT07842842T patent/PT2068938E/pt unknown
- 2007-09-20 KR KR1020097005757A patent/KR20090065512A/ko not_active Application Discontinuation
- 2007-09-20 BR BRPI0717099-8A patent/BRPI0717099A2/pt not_active IP Right Cessation
- 2007-09-20 JP JP2009529384A patent/JP5735742B2/ja not_active Expired - Fee Related
- 2007-09-21 CL CL200702725A patent/CL2007002725A1/es unknown
- 2007-09-21 TW TW096135633A patent/TWI398251B/zh not_active IP Right Cessation
-
2009
- 2009-02-20 ZA ZA2009/01220A patent/ZA200901220B/en unknown
- 2009-02-26 IL IL197296A patent/IL197296A/en not_active IP Right Cessation
- 2009-03-19 TN TN2009000094A patent/TN2009000094A1/fr unknown
- 2009-04-10 MA MA31775A patent/MA30786B1/fr unknown
- 2009-04-16 NO NO20091490A patent/NO20091490L/no not_active Application Discontinuation
- 2009-12-04 HK HK09111401.1A patent/HK1133194A1/xx not_active IP Right Cessation
-
2011
- 2011-03-23 CY CY20111100319T patent/CY1111356T1/el unknown
- 2011-04-07 HR HR20110250T patent/HRP20110250T1/hr unknown
-
2016
- 2016-09-22 US US15/272,576 patent/US20170007605A1/en not_active Abandoned
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