PL194123B1 - Atenuowana inwazyjna bakteria wewnątrzkomórkowa rodzaju Listeria, plazmid oraz wektor i szczepionkają zawierające - Google Patents
Atenuowana inwazyjna bakteria wewnątrzkomórkowa rodzaju Listeria, plazmid oraz wektor i szczepionkają zawierająceInfo
- Publication number
- PL194123B1 PL194123B1 PL98341530A PL34153098A PL194123B1 PL 194123 B1 PL194123 B1 PL 194123B1 PL 98341530 A PL98341530 A PL 98341530A PL 34153098 A PL34153098 A PL 34153098A PL 194123 B1 PL194123 B1 PL 194123B1
- Authority
- PL
- Poland
- Prior art keywords
- promoter
- cells
- plasmid
- bacterium
- host
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Developmental Biology & Embryology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/999,391 US6143551A (en) | 1997-12-29 | 1997-12-29 | Delivery of polypeptide-encoding plasmid DNA into the cytosol of macrophages by attenuated listeria suicide bacteria |
| PCT/EP1998/008345 WO1999034007A1 (en) | 1997-12-29 | 1998-12-18 | Delivery of polypeptide-encoding plasmid dna into the cytosol of macrophages by attenuated suicide bacteria |
Publications (2)
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| PL341530A1 PL341530A1 (en) | 2001-04-23 |
| PL194123B1 true PL194123B1 (pl) | 2007-04-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| PL98341530A PL194123B1 (pl) | 1997-12-29 | 1998-12-18 | Atenuowana inwazyjna bakteria wewnątrzkomórkowa rodzaju Listeria, plazmid oraz wektor i szczepionkają zawierające |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6143551A (https=) |
| EP (1) | EP1042495A1 (https=) |
| JP (1) | JP2002500017A (https=) |
| KR (1) | KR100606322B1 (https=) |
| AU (1) | AU753888B2 (https=) |
| BR (1) | BR9814546A (https=) |
| CA (1) | CA2317111A1 (https=) |
| HU (1) | HUP0100994A3 (https=) |
| IL (2) | IL136455A0 (https=) |
| PL (1) | PL194123B1 (https=) |
| WO (1) | WO1999034007A1 (https=) |
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| US20040242520A1 (en) * | 1997-09-06 | 2004-12-02 | Mayo Foundation For Medical Education And Research, A Minnesota Corporation | Expression of immonogenic substances |
| US6080849A (en) * | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
| US6962696B1 (en) * | 1999-10-04 | 2005-11-08 | Vion Pharmaceuticals Inc. | Compositions and methods for tumor-targeted delivery of effector molecules |
| DE19949594A1 (de) * | 1999-10-14 | 2001-04-26 | Deutsches Krebsforsch | Rekombinante attenuierte Listerien zur Immuntherapie |
| AU2003240505A1 (en) * | 2002-06-05 | 2003-12-22 | Iowa State University Research Foundation, Inc. | Bacteriophage and enzymes lytic to salmonellae |
| US20050214264A1 (en) * | 2002-12-13 | 2005-09-29 | Cosenza Lawrence W | Sacromastigophoric therapeutic agent delivery system |
| US7695725B2 (en) * | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| KR101192652B1 (ko) * | 2003-02-06 | 2012-10-19 | 앤저 테라퓨틱스 인코퍼레이티드 | 비포식 세포로의 침투가 약화된 리스테리아, 리스테리아를 포함하는 백신, 및 그것의 사용방법 |
| KR101173871B1 (ko) * | 2003-02-06 | 2012-08-16 | 앤저 테라퓨틱스 인코퍼레이티드 | 변형된 독립생존 미생물, 백신 조성물 및 그것의 사용방법 |
| DE10326189A1 (de) * | 2003-06-06 | 2005-01-05 | MedInnova Gesellschaft für medizinische Innovationen aus akademischer Forschung mbH | Bakterielle Träger für Nukleotidsequenzen kodierend für Wirkstoffe |
| US7390646B2 (en) * | 2003-09-17 | 2008-06-24 | The Regents Of The University Of California | Bacterial vectors and methods of use thereof |
| US20070298012A1 (en) * | 2003-12-16 | 2007-12-27 | Ivan King | Compositions and Methods for Tumor-Targeted Delivery of Effector Molecules |
| US7842289B2 (en) | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| EP1799937A1 (en) | 2004-07-23 | 2007-06-27 | Henkin-Laby, LLC | Swimming pool cleaner debris container |
| WO2006137836A2 (en) * | 2004-08-17 | 2006-12-28 | Research Development Foundation | Bacterial vector systems |
| US20090123426A1 (en) | 2004-12-17 | 2009-05-14 | Chiang Li | Compositions for Bacterial Mediated Gene Silencing and Methods of Using the Same |
| MX2007013725A (es) | 2005-05-05 | 2008-04-09 | Sensient Flavors Inc | Produccion de beta-glucanos y mananos. |
| US20080124355A1 (en) | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
| US8241623B1 (en) | 2009-02-09 | 2012-08-14 | David Bermudes | Protease sensitivity expression system |
| US9597379B1 (en) | 2010-02-09 | 2017-03-21 | David Gordon Bermudes | Protease inhibitor combination with therapeutic proteins including antibodies |
| US8771669B1 (en) | 2010-02-09 | 2014-07-08 | David Gordon Bermudes | Immunization and/or treatment of parasites and infectious agents by live bacteria |
| US8524220B1 (en) | 2010-02-09 | 2013-09-03 | David Gordon Bermudes | Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria |
| WO2014043518A1 (en) | 2012-09-14 | 2014-03-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Brachyury protein, non-poxvirus non-yeast vectors encoding brachyury protein, and their use |
| US9593339B1 (en) | 2013-02-14 | 2017-03-14 | David Gordon Bermudes | Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| TWI658140B (zh) * | 2015-11-12 | 2019-05-01 | 昕穎生醫技術股份有限公司 | 表現異源基因的系統及其用途 |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
Family Cites Families (5)
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| GB2255561B (en) * | 1991-04-20 | 1995-06-21 | Agricultural & Food Res | Lysins from bacteriophages |
| DE59510532D1 (de) * | 1994-09-09 | 2003-02-20 | Biotec Lab Ltd | Aufschluss von bakterienzellen durch phagenlysine |
| US5877159A (en) * | 1995-05-03 | 1999-03-02 | University Of Maryland At Baltimore | Method for introducing and expressing genes in animal cells and live invasive bacterial vectors for use in the same |
| IL123569A (en) * | 1995-09-06 | 2006-10-05 | Dept Of The Army | Attenuated shigella strain for delivering a mamalian expression plasmid into a mammalian cell |
| DE19754938B4 (de) * | 1997-12-11 | 2006-04-20 | Christoph von Dr. Eichel-Streiber | TGC-Verfahren zur Induktion einer zielgerichteten, somatischen Transgenität |
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1998
- 1998-12-18 IL IL13645598A patent/IL136455A0/xx not_active IP Right Cessation
- 1998-12-18 JP JP2000526662A patent/JP2002500017A/ja active Pending
- 1998-12-18 BR BR9814546-0A patent/BR9814546A/pt not_active Application Discontinuation
- 1998-12-18 WO PCT/EP1998/008345 patent/WO1999034007A1/en not_active Ceased
- 1998-12-18 PL PL98341530A patent/PL194123B1/pl unknown
- 1998-12-18 EP EP98965287A patent/EP1042495A1/en not_active Withdrawn
- 1998-12-18 HU HU0100994A patent/HUP0100994A3/hu unknown
- 1998-12-18 CA CA002317111A patent/CA2317111A1/en not_active Abandoned
- 1998-12-18 KR KR1020007007207A patent/KR100606322B1/ko not_active Expired - Fee Related
- 1998-12-18 AU AU20547/99A patent/AU753888B2/en not_active Ceased
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2000
- 2000-03-22 US US09/532,964 patent/US20020045587A1/en not_active Abandoned
- 2000-05-30 IL IL136455A patent/IL136455A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0100994A2 (hu) | 2001-07-30 |
| EP1042495A1 (en) | 2000-10-11 |
| US6143551A (en) | 2000-11-07 |
| AU753888B2 (en) | 2002-10-31 |
| BR9814546A (pt) | 2000-10-10 |
| PL341530A1 (en) | 2001-04-23 |
| KR100606322B1 (ko) | 2006-08-02 |
| AU2054799A (en) | 1999-07-19 |
| KR20010033684A (ko) | 2001-04-25 |
| IL136455A (en) | 2007-06-03 |
| US20020045587A1 (en) | 2002-04-18 |
| CA2317111A1 (en) | 1999-07-08 |
| HUP0100994A3 (en) | 2003-10-28 |
| WO1999034007A1 (en) | 1999-07-08 |
| IL136455A0 (en) | 2001-06-14 |
| JP2002500017A (ja) | 2002-01-08 |
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