PL1924574T3 - Sposób syntezy 5-(metylo-1H-imidazol-10-ilo)-3-(trifluorometylo)-benzenoaminy - Google Patents

Sposób syntezy 5-(metylo-1H-imidazol-10-ilo)-3-(trifluorometylo)-benzenoaminy

Info

Publication number
PL1924574T3
PL1924574T3 PL06772448T PL06772448T PL1924574T3 PL 1924574 T3 PL1924574 T3 PL 1924574T3 PL 06772448 T PL06772448 T PL 06772448T PL 06772448 T PL06772448 T PL 06772448T PL 1924574 T3 PL1924574 T3 PL 1924574T3
Authority
PL
Poland
Prior art keywords
syntesis
benzeneamine
imidazol
methyl
tri fluorome
Prior art date
Application number
PL06772448T
Other languages
English (en)
Polish (pl)
Inventor
Joseph Mckenna
Wen-Chung Shieh
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL1924574T3 publication Critical patent/PL1924574T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
PL06772448T 2005-06-09 2006-06-07 Sposób syntezy 5-(metylo-1H-imidazol-10-ilo)-3-(trifluorometylo)-benzenoaminy PL1924574T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68897705P 2005-06-09 2005-06-09
US70559005P 2005-08-04 2005-08-04
EP06772448A EP1924574B1 (en) 2005-06-09 2006-06-07 Process for the syntesis of 5-(methyl-1h-imidazol-1-yl)-3-(tri fluorome th yl)-benzeneamine
PCT/US2006/022155 WO2006135641A2 (en) 2005-06-09 2006-06-07 PROCESS FOR THE SYNTHESIS OF 5- (METHYL-lH-IMIDAZOL-l-YL) -3- (TRI FLUOROME TH YL) -BENZENEAMINE

Publications (1)

Publication Number Publication Date
PL1924574T3 true PL1924574T3 (pl) 2011-04-29

Family

ID=37091153

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06772448T PL1924574T3 (pl) 2005-06-09 2006-06-07 Sposób syntezy 5-(metylo-1H-imidazol-10-ilo)-3-(trifluorometylo)-benzenoaminy

Country Status (31)

Country Link
US (2) US8124763B2 (enExample)
EP (1) EP1924574B1 (enExample)
JP (1) JP5118024B2 (enExample)
KR (3) KR20120066067A (enExample)
AR (1) AR053890A1 (enExample)
AT (1) ATE487709T1 (enExample)
AU (1) AU2006258051B2 (enExample)
BR (1) BRPI0611663A2 (enExample)
CA (1) CA2610105C (enExample)
CY (1) CY1111428T1 (enExample)
DE (1) DE602006018156D1 (enExample)
DK (1) DK1924574T3 (enExample)
EC (1) ECSP077982A (enExample)
EG (1) EG25039A (enExample)
GT (1) GT200600217A (enExample)
IL (1) IL187421A (enExample)
JO (1) JO2636B1 (enExample)
MA (1) MA29599B1 (enExample)
MX (1) MX2007015423A (enExample)
MY (1) MY147436A (enExample)
NO (1) NO340743B1 (enExample)
NZ (1) NZ563740A (enExample)
PE (1) PE20070015A1 (enExample)
PL (1) PL1924574T3 (enExample)
PT (1) PT1924574E (enExample)
RU (1) RU2444520C2 (enExample)
SA (1) SA06270147B1 (enExample)
SI (1) SI1924574T1 (enExample)
TN (1) TNSN07463A1 (enExample)
TW (1) TWI430999B (enExample)
WO (1) WO2006135641A2 (enExample)

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EP2305667A3 (en) 2008-07-17 2011-05-11 Teva Pharmaceutical Industries Ltd. Nilotinib intermediates and preparation thereof
HRP20120793T1 (hr) 2008-11-05 2012-12-31 Teva Pharmaceutical Industries Ltd. Kristalni oblici nilotinib hci
WO2010060074A1 (en) * 2008-11-24 2010-05-27 Teva Pharmaceutical Industries Ltd. Preparation of nilotinib and intermediates thereof
US20110053968A1 (en) 2009-06-09 2011-03-03 Auspex Pharmaceuticals, Inc. Aminopyrimidine inhibitors of tyrosine kinase
JO3634B1 (ar) 2009-11-17 2020-08-27 Novartis Ag طريقة لعلاج اضطرابات تكاثرية وحالات مرضية أخرى متوسطة بنشاط كيناز bcr-abl، c-kit، ddr1، ddr2، أو pdgf-r
JP5841234B2 (ja) 2011-03-31 2016-01-13 ザ プロクター アンド ギャンブルカンパニー フケ／脂漏性皮膚炎の治療に有効な皮膚活性剤を特定及び評価するためのシステム、モデル、及び方法
AR086913A1 (es) * 2011-06-14 2014-01-29 Novartis Ag 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida amorfa, forma de dosificacion que la contiene y metodo para prepararlas
GB2514285B (en) 2012-02-13 2018-07-18 Grindeks Jsc Intermediates for a novel process of preparing imatinib and related tyrosine kinase inhibitors
MX2014014898A (es) 2012-06-06 2015-03-04 Procter & Gamble Sistemas y metodos de identificacion de agentes cosmeticos para composiciones para el cuidado del cabello/cuero cabelludo.
WO2015092624A1 (en) 2013-12-16 2015-06-25 Ranbaxy Laboratories Limited Nilotinib mono-oxalate and its crystalline form
CN103694176B (zh) 2014-01-07 2015-02-18 苏州立新制药有限公司 尼洛替尼中间体的制备方法
EP3095782A1 (en) 2015-05-18 2016-11-23 Esteve Química, S.A. New method for preparing 3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
CN111683976B (zh) 2018-02-05 2022-11-18 生物辐射实验室股份有限公司 具有阴离子交换-疏水混合模式配体的色谱树脂
TWI787523B (zh) 2018-06-15 2022-12-21 漢達生技醫藥股份有限公司 達沙替尼十二烷基硫酸鹽之結晶
JP2020007240A (ja) * 2018-07-04 2020-01-16 住友化学株式会社 ベンズアミド化合物の製造方法

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AU5539294A (en) 1992-12-24 1994-07-19 Hemagen/Pfc Fluorocarbon emulsions
TW406020B (en) 1993-09-29 2000-09-21 Bristol Myers Squibb Co Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
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US5726181A (en) 1995-06-05 1998-03-10 Bionumerik Pharmaceuticals, Inc. Formulations and compositions of poorly water soluble camptothecin derivatives
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AR013261A1 (es) 1997-08-01 2000-12-13 Smithkline Beecham Corp Formulaciones farmaceuticas para analogos de camptotecina en capsula de gelatina
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US6395916B1 (en) 1998-07-10 2002-05-28 Massachusetts Institute Of Technology Ligands for metals and improved metal-catalyzed processes based thereon
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IT1306129B1 (it) 1999-04-13 2001-05-30 Sigma Tau Ind Farmaceuti Esteri della l-carnitina o di alcanoil l-carnitine utilizzabili comelipidi cationici per l'immissione intracellulare di composti
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JP4426749B2 (ja) 2002-07-11 2010-03-03 株式会社産学連携機構九州 Ｏ／ｗ型エマルション製剤
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JP2006199590A (ja) 2003-09-04 2006-08-03 Nano Career Kk 水溶性の塩基性薬物内包ナノ粒子含有組成物
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DK1694242T3 (da) 2003-12-17 2014-06-30 Bionumerik Pharmaceuticals Inc Fremgangsmåde til fremstilling af farmaceutiske 7-(2-trimethylsilylethyl)camptothecinpræparater
GT200500310A (es) 2004-11-19 2006-06-19 Compuestos organicos

Also Published As

Publication number Publication date
ATE487709T1 (de) 2010-11-15
AU2006258051A1 (en) 2006-12-21
EP1924574B1 (en) 2010-11-10
GT200600217A (es) 2007-03-28
KR20120066067A (ko) 2012-06-21
RU2007148231A (ru) 2009-07-20
TW200726756A (en) 2007-07-16
US8124763B2 (en) 2012-02-28
MA29599B1 (fr) 2008-07-01
KR20080022093A (ko) 2008-03-10
KR101514593B1 (ko) 2015-04-22
JO2636B1 (en) 2012-06-17
CA2610105A1 (en) 2006-12-21
WO2006135641A2 (en) 2006-12-21
JP5118024B2 (ja) 2013-01-16
NZ563740A (en) 2011-03-31
JP2008545786A (ja) 2008-12-18
HK1117524A1 (en) 2009-01-16
US20120116081A1 (en) 2012-05-10
DE602006018156D1 (de) 2010-12-23
CY1111428T1 (el) 2015-08-05
US20080188656A1 (en) 2008-08-07
TNSN07463A1 (en) 2009-03-17
ECSP077982A (es) 2008-01-23
CA2610105C (en) 2014-03-25
NO20080157L (no) 2008-01-09
NO340743B1 (no) 2017-06-12
PE20070015A1 (es) 2007-02-06
RU2444520C2 (ru) 2012-03-10
AR053890A1 (es) 2007-05-23
MY147436A (en) 2012-12-14
MX2007015423A (es) 2008-02-21
EG25039A (en) 2011-07-06
US8946416B2 (en) 2015-02-03
KR101216249B1 (ko) 2012-12-28
AU2006258051B2 (en) 2010-09-09
EP1924574A2 (en) 2008-05-28
DK1924574T3 (da) 2011-02-14
TWI430999B (zh) 2014-03-21
PT1924574E (pt) 2011-02-08
IL187421A0 (en) 2008-02-09
SA06270147B1 (ar) 2009-12-22
BRPI0611663A2 (pt) 2010-09-28
WO2006135641A3 (en) 2007-03-29
KR20130118394A (ko) 2013-10-29
SI1924574T1 (sl) 2011-02-28
IL187421A (en) 2011-11-30

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