PL1919466T3 - Formulacje do leczenia nieprawidłowości lipoproteinowych obejmujące statynę i pochodną metylonikotynoamidu - Google Patents

Formulacje do leczenia nieprawidłowości lipoproteinowych obejmujące statynę i pochodną metylonikotynoamidu

Info

Publication number
PL1919466T3
PL1919466T3 PL06848969T PL06848969T PL1919466T3 PL 1919466 T3 PL1919466 T3 PL 1919466T3 PL 06848969 T PL06848969 T PL 06848969T PL 06848969 T PL06848969 T PL 06848969T PL 1919466 T3 PL1919466 T3 PL 1919466T3
Authority
PL
Poland
Prior art keywords
statin
methylnicotinamide
formulations
derivative
treatment
Prior art date
Application number
PL06848969T
Other languages
English (en)
Inventor
Robert Bender
Stefan Chłopicki
Jerzy Gębicki
Original Assignee
Cortria Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortria Corp filed Critical Cortria Corp
Publication of PL1919466T3 publication Critical patent/PL1919466T3/pl

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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    • A61K31/47Quinolines; Isoquinolines
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    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P3/06Antihyperlipidemics
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
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  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL06848969T 2005-07-11 2006-07-11 Formulacje do leczenia nieprawidłowości lipoproteinowych obejmujące statynę i pochodną metylonikotynoamidu PL1919466T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69829205P 2005-07-11 2005-07-11
EP06848969A EP1919466B9 (en) 2005-07-11 2006-07-11 Formulations for treatment of lipoprotein abnormalities comprising a statin and a methylnicotinamide derivative
PCT/IB2006/004013 WO2007074406A2 (en) 2005-07-11 2006-07-11 Formulations for treatment of lipoprotein abnormalities comprising a statin a statin and a methylnicotinamide derivative

Publications (1)

Publication Number Publication Date
PL1919466T3 true PL1919466T3 (pl) 2012-05-31

Family

ID=38218362

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06848969T PL1919466T3 (pl) 2005-07-11 2006-07-11 Formulacje do leczenia nieprawidłowości lipoproteinowych obejmujące statynę i pochodną metylonikotynoamidu

Country Status (11)

Country Link
US (3) US20070021379A1 (pl)
EP (1) EP1919466B9 (pl)
JP (1) JP5490409B2 (pl)
AT (1) ATE548035T1 (pl)
AU (1) AU2006329564A1 (pl)
CA (1) CA2614885C (pl)
DK (1) DK1919466T3 (pl)
ES (1) ES2383822T3 (pl)
PL (1) PL1919466T3 (pl)
PT (1) PT1919466E (pl)
WO (1) WO2007074406A2 (pl)

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EP2203055A4 (en) * 2007-09-28 2010-12-15 1-METHYL NICOTINAMIDE AND DERIVATIVES FOR THE TREATMENT OF GASTRIC INJURY
WO2009047290A1 (en) * 2007-10-12 2009-04-16 Politechnika Lodzka Use of quaternary pyridinium salts for radioprotection
US8304439B1 (en) 2007-10-12 2012-11-06 Politechnika Lodzka Use of quaternary pyridinium salts as a therapeutic or preventing agent against ionizing radiation-induced damage
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CA2889035A1 (en) * 2012-10-24 2014-05-01 Biocopea Limited Drug combinations and uses
ES2967074T3 (es) * 2016-07-18 2024-04-25 Pharmena S A 1 metilnicotinamida para el tratamiento de una enfermedad cardiovascular
WO2018015862A1 (en) * 2016-07-18 2018-01-25 Pharmena S.A. 1-methylnicotinamide salts for use in raising the blood levels of adiponectin
CN108478573A (zh) * 2018-03-30 2018-09-04 浙江中医药大学 一种1-甲基烟酰胺在制备预防或治疗酒精性脂肪肝药物中的应用
WO2020115765A1 (en) 2018-12-05 2020-06-11 Celagenex Research (India) Pvt. Ltd. Novel synergistic composition comprising sirt1 and ampk activators for treating metabolic syndrome
CN111138427B (zh) 2018-12-05 2021-09-17 江西富祥药业股份有限公司 黄连素及其类似物的非诺贝特酸盐、晶型、制备方法及应用
WO2020141552A1 (en) * 2019-01-02 2020-07-09 Celagenex Research (India) Pvt. Ltd. Potent synergistic compositions of vasoactive mediators enhancers for improving vascular endothelial function
WO2021205341A1 (en) 2020-04-07 2021-10-14 Pharmena S.A. 1-methylnicotinamide for the prevention/treatment of inflammatory airway diseases
CN115837023B (zh) * 2023-02-20 2023-05-16 中山大学附属第八医院(深圳福田) 1-甲基烟酰胺在制备抗血管钙化药物中的应用

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ATE548035T1 (de) 2012-03-15
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EP1919466A2 (en) 2008-05-14
JP5490409B2 (ja) 2014-05-14
US8481570B2 (en) 2013-07-09
EP1919466B1 (en) 2012-03-07
CA2614885A1 (en) 2007-07-05
US20120245115A1 (en) 2012-09-27
US20070021379A1 (en) 2007-01-25
CA2614885C (en) 2015-03-17
US8211922B2 (en) 2012-07-03
US20100120726A1 (en) 2010-05-13
PT1919466E (pt) 2012-05-21
WO2007074406A3 (en) 2007-11-08
WO2007074406A2 (en) 2007-07-05
AU2006329564A1 (en) 2007-07-05
EP1919466B9 (en) 2012-05-16

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