DK1919466T3 - Formuleringer til behandling af lipoprotein-abnormiteter omfattende et statin og et methylnicotinamidderivat - Google Patents

Formuleringer til behandling af lipoprotein-abnormiteter omfattende et statin og et methylnicotinamidderivat

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Publication number
DK1919466T3
DK1919466T3 DK06848969.9T DK06848969T DK1919466T3 DK 1919466 T3 DK1919466 T3 DK 1919466T3 DK 06848969 T DK06848969 T DK 06848969T DK 1919466 T3 DK1919466 T3 DK 1919466T3
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Prior art keywords
statin
methylnicotinamide
formulations
derivative
treatment
Prior art date
Application number
DK06848969.9T
Other languages
English (en)
Inventor
Robert Bender
Stefan Chlopicki
Jerzy Gebicki
Original Assignee
Cortria Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of DK1919466T3 publication Critical patent/DK1919466T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
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    • A61P27/02Ophthalmic agents
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P9/12Antihypertensives

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  • Psychiatry (AREA)
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  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK06848969.9T 2005-07-11 2006-07-11 Formuleringer til behandling af lipoprotein-abnormiteter omfattende et statin og et methylnicotinamidderivat DK1919466T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69829205P 2005-07-11 2005-07-11
PCT/IB2006/004013 WO2007074406A2 (en) 2005-07-11 2006-07-11 Formulations for treatment of lipoprotein abnormalities comprising a statin a statin and a methylnicotinamide derivative

Publications (1)

Publication Number Publication Date
DK1919466T3 true DK1919466T3 (da) 2012-07-02

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ID=38218362

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06848969.9T DK1919466T3 (da) 2005-07-11 2006-07-11 Formuleringer til behandling af lipoprotein-abnormiteter omfattende et statin og et methylnicotinamidderivat

Country Status (11)

Country Link
US (3) US20070021379A1 (da)
EP (1) EP1919466B9 (da)
JP (1) JP5490409B2 (da)
AT (1) ATE548035T1 (da)
AU (1) AU2006329564A1 (da)
CA (1) CA2614885C (da)
DK (1) DK1919466T3 (da)
ES (1) ES2383822T3 (da)
PL (1) PL1919466T3 (da)
PT (1) PT1919466E (da)
WO (1) WO2007074406A2 (da)

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CN111138427B (zh) 2018-12-05 2021-09-17 江西富祥药业股份有限公司 黄连素及其类似物的非诺贝特酸盐、晶型、制备方法及应用
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WO2007074406A3 (en) 2007-11-08
EP1919466B1 (en) 2012-03-07
ES2383822T3 (es) 2012-06-26
JP2009500445A (ja) 2009-01-08
ATE548035T1 (de) 2012-03-15
EP1919466B9 (en) 2012-05-16
US8211922B2 (en) 2012-07-03
US20070021379A1 (en) 2007-01-25
AU2006329564A1 (en) 2007-07-05
JP5490409B2 (ja) 2014-05-14
EP1919466A2 (en) 2008-05-14
US8481570B2 (en) 2013-07-09
US20100120726A1 (en) 2010-05-13
WO2007074406A2 (en) 2007-07-05
CA2614885C (en) 2015-03-17
CA2614885A1 (en) 2007-07-05
PL1919466T3 (pl) 2012-05-31
US20120245115A1 (en) 2012-09-27
PT1919466E (pt) 2012-05-21

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