NO20076206L - Kombinasjon av PDE4 inhibitor romflumilast og et tetrahydrobioterin-derivativ - Google Patents
Kombinasjon av PDE4 inhibitor romflumilast og et tetrahydrobioterin-derivativInfo
- Publication number
- NO20076206L NO20076206L NO20076206A NO20076206A NO20076206L NO 20076206 L NO20076206 L NO 20076206L NO 20076206 A NO20076206 A NO 20076206A NO 20076206 A NO20076206 A NO 20076206A NO 20076206 L NO20076206 L NO 20076206L
- Authority
- NO
- Norway
- Prior art keywords
- derivative
- combination
- tetrahydrobioterine
- rumflumilast
- pde4 inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Oppfinnelsen beskriver anvendelsen av en PDE4-inhibitor i kombinasjon med BH4 eller et BH4-derivat for forebygging og/eller behandling av respiratoriske sykdommer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05103938 | 2005-05-11 | ||
PCT/EP2006/062117 WO2006120176A2 (en) | 2005-05-11 | 2006-05-08 | Combination of the pde4 inhibitor roflumilast and a tetrahydrobiopterin derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20076206L true NO20076206L (no) | 2007-12-11 |
Family
ID=35125407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20076206A NO20076206L (no) | 2005-05-11 | 2007-12-03 | Kombinasjon av PDE4 inhibitor romflumilast og et tetrahydrobioterin-derivativ |
Country Status (14)
Country | Link |
---|---|
US (1) | US20080221111A1 (no) |
EP (1) | EP1940392A2 (no) |
JP (1) | JP2008540486A (no) |
KR (1) | KR20080005601A (no) |
CN (1) | CN101171005A (no) |
AU (1) | AU2006245770A1 (no) |
BR (1) | BRPI0612796A2 (no) |
CA (1) | CA2607331A1 (no) |
EA (1) | EA200702358A1 (no) |
IL (1) | IL186804A0 (no) |
MX (1) | MX2007013766A (no) |
NO (1) | NO20076206L (no) |
WO (1) | WO2006120176A2 (no) |
ZA (1) | ZA200708776B (no) |
Families Citing this family (67)
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CA2631740A1 (en) * | 2005-12-05 | 2007-06-14 | Biomarin Pharmaceutical Inc. | Methods and compositions for the treatment of disease |
WO2008089148A1 (en) * | 2007-01-12 | 2008-07-24 | Biomarin Pharmaceutical Inc. | Method of treating a metabolic or neuropsychiatry disorder with a bh4 derivative prodrug |
CN101827852B (zh) | 2007-10-19 | 2014-07-30 | 贝林格尔.英格海姆国际有限公司 | 取代的哌啶子基-二氢噻吩并嘧啶 |
PL2309983T3 (pl) * | 2008-08-12 | 2019-09-30 | Orpha Swiss Gmbh | Farmaceutyczna postać podawania zawierająca tetrahydrobiopterynę |
WO2010070032A1 (en) | 2008-12-19 | 2010-06-24 | Boehringer Ingelheim International Gmbh | Cyclic pyrimidin-4-carboxamides as ccr2 receptor antagonists for treatment of inflammation, asthma and copd |
WO2010097374A1 (de) | 2009-02-26 | 2010-09-02 | Boehringer Ingelheim International Gmbh | Verbindungen als bradykinin-b1-antagonisten |
MY153941A (en) | 2009-02-26 | 2015-04-15 | Boehringer Ingelheim Int | Compounds as bradykinin b1 antagonists |
WO2010097373A1 (de) | 2009-02-26 | 2010-09-02 | Boehringer Ingelheim International Gmbh | Verbindungen als bradykinin b1 antagonisten |
PL2539323T6 (pl) | 2010-02-23 | 2018-05-30 | Boehringer Ingelheim International Gmbh | Związki jako antagoniści bradykininy B1 |
JP5066756B2 (ja) | 2010-04-22 | 2012-11-07 | 学校法人日本大学 | 脳機能障害予防・改善用の薬剤及び飲食物 |
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US20130059866A1 (en) | 2011-08-24 | 2013-03-07 | Boehringer Ingelheim International Gmbh | Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma |
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WO2019147824A1 (en) | 2018-01-26 | 2019-08-01 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor |
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Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5877176A (en) * | 1991-12-26 | 1999-03-02 | Cornell Research Foundation, Inc. | Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis |
US5830461A (en) * | 1992-11-25 | 1998-11-03 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Methods for promoting wound healing and treating transplant-associated vasculopathy |
US5712298A (en) * | 1993-07-02 | 1998-01-27 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Fluoroalkoxy-substituted benzamides and their use as cyclic nucleotide phosphodiesterase inhibitors |
DE4418097A1 (de) * | 1994-05-24 | 1995-11-30 | Cassella Ag | Verwendung von Tetrahydropteridin-Derivaten als Hemmstoffe der NO-Synthase |
WO1998008516A1 (fr) * | 1996-08-30 | 1998-03-05 | Suntory Limited | Preparations servant a la prevention et au traitement de maladies provoquees par une hypofonction de l'oxyde nitrique synthase |
SE0000307D0 (sv) * | 2000-01-31 | 2000-01-31 | Univ Zuerich | Method and formulation för treatment of vasoconstriction |
US6544994B2 (en) * | 2000-06-07 | 2003-04-08 | Eprov Ag | Pharmaceutical preparation for treating or preventing cardiovascular or neurological disorders by modulating of the activity of nitric oxide synthase |
JP2007509909A (ja) * | 2003-10-31 | 2007-04-19 | アルタナ ファルマ アクチエンゲゼルシャフト | 呼吸器疾患の治療のためのbh4の使用 |
-
2006
- 2006-05-08 MX MX2007013766A patent/MX2007013766A/es not_active Application Discontinuation
- 2006-05-08 KR KR1020077028279A patent/KR20080005601A/ko not_active Application Discontinuation
- 2006-05-08 US US11/919,742 patent/US20080221111A1/en not_active Abandoned
- 2006-05-08 EP EP06755065A patent/EP1940392A2/en not_active Withdrawn
- 2006-05-08 AU AU2006245770A patent/AU2006245770A1/en not_active Abandoned
- 2006-05-08 WO PCT/EP2006/062117 patent/WO2006120176A2/en active Application Filing
- 2006-05-08 CA CA002607331A patent/CA2607331A1/en not_active Abandoned
- 2006-05-08 EA EA200702358A patent/EA200702358A1/ru unknown
- 2006-05-08 BR BRPI0612796-7A patent/BRPI0612796A2/pt not_active IP Right Cessation
- 2006-05-08 CN CNA2006800148286A patent/CN101171005A/zh active Pending
- 2006-05-08 JP JP2008510556A patent/JP2008540486A/ja not_active Withdrawn
-
2007
- 2007-10-15 ZA ZA200708776A patent/ZA200708776B/xx unknown
- 2007-10-21 IL IL186804A patent/IL186804A0/en unknown
- 2007-12-03 NO NO20076206A patent/NO20076206L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EA200702358A1 (ru) | 2008-04-28 |
IL186804A0 (en) | 2008-06-05 |
CA2607331A1 (en) | 2006-11-16 |
AU2006245770A1 (en) | 2006-11-16 |
WO2006120176A3 (en) | 2007-04-19 |
US20080221111A1 (en) | 2008-09-11 |
BRPI0612796A2 (pt) | 2010-11-30 |
JP2008540486A (ja) | 2008-11-20 |
ZA200708776B (en) | 2008-10-29 |
WO2006120176A2 (en) | 2006-11-16 |
CN101171005A (zh) | 2008-04-30 |
EP1940392A2 (en) | 2008-07-09 |
KR20080005601A (ko) | 2008-01-14 |
MX2007013766A (es) | 2008-01-28 |
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Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104 |
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