PL364348A1 - Zastosowanie czwartorzędowych soli pirydyniowych jako środka naczynioprotekcyjnego - Google Patents
Zastosowanie czwartorzędowych soli pirydyniowych jako środka naczynioprotekcyjnegoInfo
- Publication number
- PL364348A1 PL364348A1 PL04364348A PL36434804A PL364348A1 PL 364348 A1 PL364348 A1 PL 364348A1 PL 04364348 A PL04364348 A PL 04364348A PL 36434804 A PL36434804 A PL 36434804A PL 364348 A1 PL364348 A1 PL 364348A1
- Authority
- PL
- Poland
- Prior art keywords
- application
- protection agent
- pyridine salts
- vessel protection
- quaternary pyridine
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nutrition Science (AREA)
- Pulmonology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Physiology (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Psychology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL04364348A PL364348A1 (pl) | 2004-01-12 | 2004-01-12 | Zastosowanie czwartorzędowych soli pirydyniowych jako środka naczynioprotekcyjnego |
CA2547234A CA2547234C (en) | 2004-01-12 | 2005-01-07 | The use of quaternary pyridinium salts as vasoprotective agents |
ES05726215T ES2372756T3 (es) | 2004-01-12 | 2005-01-07 | Uso de sales de piridinio cuaternario como agentes vasoprotectores. |
RU2006129299/15A RU2366420C2 (ru) | 2004-01-12 | 2005-01-07 | Применение четвертичных солей пиридиния в качестве вазопротекторных средств |
EP10180501A EP2279738A1 (en) | 2004-01-12 | 2005-01-07 | The use of quaternary pyridinium salts as vasoprotective agents |
JP2006548308A JP5052138B2 (ja) | 2004-01-12 | 2005-01-07 | 四級ピリジニウム塩の血管保護剤としての使用 |
AU2005205066A AU2005205066C1 (en) | 2004-01-12 | 2005-01-07 | The use of quaternary pyridinium salts as vasoprotective agents |
PL05726215T PL1713480T3 (pl) | 2004-01-12 | 2005-01-07 | Zastosowanie czwartorzędowych soli pirydyniowych jako środków naczynioprotekcyjnych |
US10/585,892 US7935717B2 (en) | 2004-01-12 | 2005-01-07 | Method for treating hypertriglyceridemia, dyslipidemia and hypercholesterolemia with a 1-methylnicotinamide salt |
AT05726215T ATE524179T1 (de) | 2004-01-12 | 2005-01-07 | Verwendung von quartären pyridiniumsalzen als gefässschutzmittel |
CN2005800017124A CN1905875B (zh) | 2004-01-12 | 2005-01-07 | 吡啶*盐作为血管保护剂的用途 |
EP05726215A EP1713480B1 (en) | 2004-01-12 | 2005-01-07 | The use of quaternary pyridinium salts as vasoprotective agents |
PCT/EP2005/050057 WO2005067927A2 (en) | 2004-01-12 | 2005-01-07 | The use of quaternary pyridinium salts as vasoprotective agents |
PT05726215T PT1713480E (pt) | 2004-01-12 | 2005-01-07 | Utilização de sais quaternários de piridínio como agentes vasoprotectores |
DK05726215.6T DK1713480T3 (da) | 2004-01-12 | 2005-01-07 | Anvendelse af kvaternære pyridiniumsalte som vasobeskyttende midler |
US12/685,377 US8124631B2 (en) | 2004-01-12 | 2010-01-11 | Use of quaternary pyridinium salts as vasoprotective agents |
US13/083,106 US8969391B2 (en) | 2004-01-12 | 2011-04-08 | Use quaternary pyridinium salts as vasoprotective agents |
JP2011233155A JP5597179B2 (ja) | 2004-01-12 | 2011-10-24 | 四級ピリジニウム塩の血管保護剤としての使用 |
US14/303,054 US9119844B2 (en) | 2004-01-12 | 2014-06-12 | Use of quaternary pyridinium salts as vasoprotective agents |
US14/598,888 US9333196B2 (en) | 2004-01-12 | 2015-01-16 | Use of quaternary pyridinium salts as vasoprotective agents |
US15/146,485 US9675601B2 (en) | 2004-01-12 | 2016-05-04 | Use of quaternary pyridinium salts as vasoprotective agents |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL04364348A PL364348A1 (pl) | 2004-01-12 | 2004-01-12 | Zastosowanie czwartorzędowych soli pirydyniowych jako środka naczynioprotekcyjnego |
Publications (1)
Publication Number | Publication Date |
---|---|
PL364348A1 true PL364348A1 (pl) | 2005-07-25 |
Family
ID=34793495
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL04364348A PL364348A1 (pl) | 2004-01-12 | 2004-01-12 | Zastosowanie czwartorzędowych soli pirydyniowych jako środka naczynioprotekcyjnego |
PL05726215T PL1713480T3 (pl) | 2004-01-12 | 2005-01-07 | Zastosowanie czwartorzędowych soli pirydyniowych jako środków naczynioprotekcyjnych |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL05726215T PL1713480T3 (pl) | 2004-01-12 | 2005-01-07 | Zastosowanie czwartorzędowych soli pirydyniowych jako środków naczynioprotekcyjnych |
Country Status (13)
Country | Link |
---|---|
US (6) | US7935717B2 (pl) |
EP (2) | EP2279738A1 (pl) |
JP (2) | JP5052138B2 (pl) |
CN (1) | CN1905875B (pl) |
AT (1) | ATE524179T1 (pl) |
AU (1) | AU2005205066C1 (pl) |
CA (1) | CA2547234C (pl) |
DK (1) | DK1713480T3 (pl) |
ES (1) | ES2372756T3 (pl) |
PL (2) | PL364348A1 (pl) |
PT (1) | PT1713480E (pl) |
RU (1) | RU2366420C2 (pl) |
WO (1) | WO2005067927A2 (pl) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014200373A1 (en) * | 2013-06-11 | 2014-12-18 | Uniwersytet Jagielloński | 3-carbamoyl-1 -methylpyridinium nitrite, process for its preparation and its use |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL364348A1 (pl) | 2004-01-12 | 2005-07-25 | PHARMENA Sp.z o.o. | Zastosowanie czwartorzędowych soli pirydyniowych jako środka naczynioprotekcyjnego |
PL1919466T3 (pl) * | 2005-07-11 | 2012-05-31 | Cortria Corp | Formulacje do leczenia nieprawidłowości lipoproteinowych obejmujące statynę i pochodną metylonikotynoamidu |
CA2629913A1 (en) * | 2005-12-09 | 2007-06-14 | Cerecon Ag | Quaternary 3 -amido, n-methylpyridinium salts as anti -inflammatory agents |
JP2009529057A (ja) | 2006-03-08 | 2009-08-13 | コートリア・コーポレーシヨン | Cox−関連胃損傷を予防するための非−選択的cox阻害剤との組み合わせ療法 |
EP2079471A2 (en) * | 2006-10-18 | 2009-07-22 | Dermena | Food extracts containing n-methylnicotinamide for treatment of lipoprotein abnormalities and skin diseases and disorders |
PL381862A1 (pl) * | 2007-02-28 | 2008-09-01 | Trigendo Spółka Z Ograniczoną Odpowiedzialnością | Zastosowanie związków pirydyniowych i sposób leczenia |
EP2203055A4 (en) * | 2007-09-28 | 2010-12-15 | 1-METHYL NICOTINAMIDE AND DERIVATIVES FOR THE TREATMENT OF GASTRIC INJURY | |
PL2211857T3 (pl) * | 2007-10-12 | 2012-11-30 | Politechnika Lodzka | Zastosowanie czwartorzędowych soli pirydyniowych do radioprotekcji |
EP2211858B1 (en) | 2007-10-12 | 2015-03-25 | Politechnika Lodzka | Use of quaternary pyridinium salts for inhibiting cancer metastases |
US8304439B1 (en) | 2007-10-12 | 2012-11-06 | Politechnika Lodzka | Use of quaternary pyridinium salts as a therapeutic or preventing agent against ionizing radiation-induced damage |
MX2010012106A (es) * | 2008-05-06 | 2011-03-21 | Cortria Corp | Analogos de 1-metilnicotinamida. |
PL2307380T3 (pl) * | 2008-07-01 | 2013-01-31 | Univ Jagiellonski | Pochodne N’-nitroksyalkilonikotynamidu do leczenia chorób układu sercowo-naczyniowego |
MY163762A (en) * | 2008-07-23 | 2017-10-31 | Toray Industries | Therapeutic agent for chronic renal failure |
EP2186419A1 (en) * | 2008-11-13 | 2010-05-19 | Tchibo GmbH | NMP-containing extract, a method of its production and uses thereof |
KR101309576B1 (ko) * | 2011-05-25 | 2013-09-17 | 연세대학교 산학협력단 | 대사물질을 이용한 심부전 바이오마커 |
CN105771005A (zh) * | 2016-03-24 | 2016-07-20 | 乐普(北京)医疗器械股份有限公司 | 一种抗风湿性血管狭窄药物支架及其制备方法和应用 |
JP2019521160A (ja) * | 2016-07-18 | 2019-07-25 | ファルメナ エスエー | C反応性タンパク質関連疾患の治療のための1−メチルニコチンアミド |
WO2018015862A1 (en) | 2016-07-18 | 2018-01-25 | Pharmena S.A. | 1-methylnicotinamide salts for use in raising the blood levels of adiponectin |
AU2018307807B2 (en) * | 2017-07-27 | 2024-05-02 | Eastern Michigan University | Plasminogen activator inhibitor-1 (PAI-1) inhibitor and method of use |
PL238932B1 (pl) * | 2017-12-31 | 2021-10-18 | Univ Jagiellonski | Pochodne soli pirydyniowych oraz ich zastosowanie |
US10864207B2 (en) * | 2019-01-02 | 2020-12-15 | Celagenex Research (India) Pvt. Ltd. | Method of treating endothelial dysfunction |
WO2021205341A1 (en) | 2020-04-07 | 2021-10-14 | Pharmena S.A. | 1-methylnicotinamide for the prevention/treatment of inflammatory airway diseases |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB675430A (en) | 1949-07-12 | 1952-07-09 | Cilag Ltd | Novel quaternary nicotinic acid amide derivatives and production thereof |
DE840698C (de) | 1949-07-12 | 1952-06-05 | Cilag Aktiengesellschaft | Verfahren zur herstellung neuer derivate des nicotinsaureamids |
US5260305A (en) | 1988-12-12 | 1993-11-09 | E. R. Squibb & Sons, Inc. | Combination of pravastatin and nicotinic acid or related acid and method for lowering serum cholesterol using such combination |
US6406715B1 (en) | 1993-09-20 | 2002-06-18 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique urinary metabolite profiles |
US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
US20060263428A1 (en) | 1993-09-20 | 2006-11-23 | Eugenio Cefali | Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics |
US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
US6676967B1 (en) | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
US6129930A (en) | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2014200373A1 (en) * | 2013-06-11 | 2014-12-18 | Uniwersytet Jagielloński | 3-carbamoyl-1 -methylpyridinium nitrite, process for its preparation and its use |
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