PL1871368T3 - Związki dihydropirydynowe do zastosowania w chorobach neurodegeneracyjnych i demencji - Google Patents
Związki dihydropirydynowe do zastosowania w chorobach neurodegeneracyjnych i demencjiInfo
- Publication number
- PL1871368T3 PL1871368T3 PL06740387T PL06740387T PL1871368T3 PL 1871368 T3 PL1871368 T3 PL 1871368T3 PL 06740387 T PL06740387 T PL 06740387T PL 06740387 T PL06740387 T PL 06740387T PL 1871368 T3 PL1871368 T3 PL 1871368T3
- Authority
- PL
- Poland
- Prior art keywords
- therapeutically effective
- effective amounts
- disease
- dementia
- dihydropyridine compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66766505P | 2005-04-04 | 2005-04-04 | |
US68951905P | 2005-06-13 | 2005-06-13 | |
PCT/US2006/012284 WO2006107859A2 (en) | 2005-04-04 | 2006-04-04 | Dihydropyridine compounds for neurodegenerative diseases and dementia |
EP06740387A EP1871368B1 (en) | 2005-04-04 | 2006-04-04 | Dihydropyridine compounds for neurodegenerative diseases and dementia |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1871368T3 true PL1871368T3 (pl) | 2011-12-30 |
Family
ID=37074003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL06740387T PL1871368T3 (pl) | 2005-04-04 | 2006-04-04 | Związki dihydropirydynowe do zastosowania w chorobach neurodegeneracyjnych i demencji |
Country Status (16)
Country | Link |
---|---|
US (3) | US20060270709A1 (pl) |
EP (2) | EP1871369A4 (pl) |
JP (2) | JP2008537552A (pl) |
KR (1) | KR20080007233A (pl) |
AT (1) | ATE511843T1 (pl) |
AU (1) | AU2006232517A1 (pl) |
CA (1) | CA2603258A1 (pl) |
CY (1) | CY1112427T1 (pl) |
DK (1) | DK1871368T3 (pl) |
HR (1) | HRP20110524T1 (pl) |
IL (1) | IL186412A0 (pl) |
ME (1) | ME01224B (pl) |
PL (1) | PL1871368T3 (pl) |
PT (1) | PT1871368E (pl) |
RS (1) | RS51822B (pl) |
WO (2) | WO2006107859A2 (pl) |
Families Citing this family (45)
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US7825133B2 (en) * | 2003-11-14 | 2010-11-02 | Shanghai Genomics, Inc. | Derivatives of pyridone and the use of them |
ME01224B (me) * | 2005-04-04 | 2013-06-20 | Eisai R&D Man Co Ltd | Jedinjenja dihidropiridina za liječenje neurodegenerativnih bolesti i demencije |
AU2006234627C1 (en) * | 2005-04-08 | 2009-11-26 | Eisai R & D Management Co., Ltd. | Therapeutic agent for dyskinesia |
ES2524922T3 (es) | 2005-05-10 | 2014-12-15 | Intermune, Inc. | Derivados de piridona para modular el sistema de proteína cinasa activada por estrés |
US7718807B2 (en) | 2006-04-28 | 2010-05-18 | Eisai R&D Management Co., Ltd. | Salt of 1,2-dihydropyridine compound |
CA2667553A1 (en) * | 2006-10-27 | 2008-05-02 | Medivation Neurology, Inc. | Methods and combination therapies for treating alzheimer's disease |
NZ578744A (en) * | 2007-01-31 | 2012-02-24 | Vertex Pharma | 2-aminopyridine derivatives useful as kinase inhibitors |
US20100099714A1 (en) * | 2007-03-05 | 2010-04-22 | Eisai R&D Management Co., Ltd. | AMPA and NMDA Receptor Antagonists for Neurodegenerative Diseases |
JP2010533126A (ja) * | 2007-07-13 | 2010-10-21 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 神経因性疼痛の治療ためのampa受容体アンタゴニストとアセチルコリンエステラーゼ阻害剤との併用 |
WO2009054543A1 (en) * | 2007-10-26 | 2009-04-30 | Eisai R & D Management Co., Ltd. | Ampa receptor antagonists and zonisamide for parkinson's disease and movement disorders |
EP2254577A1 (en) * | 2007-12-26 | 2010-12-01 | Eisai R&D Management Co., Ltd. | Ampa receptor antagonists for epilepsy, mental disorders or deficits in sensory organ |
US20090221554A1 (en) * | 2008-02-28 | 2009-09-03 | Zenyaku Kogyo Kabushiki Kaisha | Method of treating cognitive impairment |
US8598150B1 (en) | 2008-04-02 | 2013-12-03 | Jonathan R. Brestoff | Composition and method for affecting obesity and related conditions |
US8987245B2 (en) | 2008-04-02 | 2015-03-24 | Jonathan R. Brestoff Parker | Composition and method for affecting obesity and related conditions |
US8304413B2 (en) | 2008-06-03 | 2012-11-06 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
US8569337B2 (en) | 2008-07-23 | 2013-10-29 | Vertex Pharmaceuticals Incorporated | Tri-cyclic pyrazolopyridine kinase inhibitors |
NZ590784A (en) | 2008-07-23 | 2012-12-21 | Vertex Pharma | Pyrazolopyridine kinase inhibitors |
EP2328896B1 (en) | 2008-07-23 | 2013-10-23 | Vertex Pharmaceuticals Incorporated | Tri-cyclic pyrazolopyridine kinase inhibitors |
WO2010017350A1 (en) * | 2008-08-06 | 2010-02-11 | Vertex Pharmaceuticals Incorporated | Aminopyridine kinase inhibitors |
CN102264701A (zh) | 2008-12-23 | 2011-11-30 | 霍夫曼-拉罗奇有限公司 | 作为p2x7调节剂的二氢吡啶酮脲 |
CA2745864A1 (en) | 2008-12-23 | 2010-07-01 | F.Hoffmann-La Roche Ag | Dihydropyridone amides as p2x7 modulators |
BRPI0923488A2 (pt) | 2008-12-23 | 2019-09-24 | Hoffmann La Roche | amidas de didropiridona como modulares p2x7 |
US8153808B2 (en) | 2008-12-23 | 2012-04-10 | Roche Palo Alto Llc | Dihydropyridone amides as P2X7 modulators |
WO2010072607A1 (en) | 2008-12-23 | 2010-07-01 | F. Hoffmann-La Roche Ag | Dihydropyridone amides as p2x7 modulators |
EP2427464A1 (en) | 2009-05-06 | 2012-03-14 | Vertex Pharmaceuticals Incorporated | Pyrazolopyridines |
AU2011209649A1 (en) | 2010-01-27 | 2012-08-09 | Vertex Pharmaceuticals Incorporated | Pyrazolopyrazine kinase inhibitors |
JP5769733B2 (ja) | 2010-01-27 | 2015-08-26 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | ピラゾロピリジンキナーゼ阻害剤 |
JP2013518114A (ja) | 2010-01-27 | 2013-05-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | ピラゾロピリミジンキナーゼ阻害剤 |
JO2998B1 (ar) | 2010-06-04 | 2016-09-05 | Amgen Inc | مشتقات بيبيريدينون كمثبطات mdm2 لعلاج السرطان |
US9376425B2 (en) | 2011-09-27 | 2016-06-28 | Amgen, Inc. | Heterocyclic compounds as MDM2 inhibitors for the treatment of cancer |
ES2643507T3 (es) | 2012-03-12 | 2017-11-23 | William J. Binder | Tratamiento de las cefaleas por migraña con la neurotoxina presináptica |
US8722060B2 (en) * | 2012-05-23 | 2014-05-13 | William J. Binder | Method of treating vertigo |
AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
TW201441193A (zh) | 2012-12-06 | 2014-11-01 | Kyowa Hakko Kirin Co Ltd | 吡啶酮化合物 |
US11407721B2 (en) | 2013-02-19 | 2022-08-09 | Amgen Inc. | CIS-morpholinone and other compounds as MDM2 inhibitors for the treatment of cancer |
MX368703B (es) | 2013-02-28 | 2019-10-11 | Amgen Inc | Un inhibidor de mdm2 derivado de acido benzoico para el tratamiento del cancer. |
MX2015012427A (es) | 2013-03-14 | 2016-01-12 | Amgen Inc | Compuestos de morfolinona de acido heteroarilo como inhibidores mdm2 para el tratamiento de cancer. |
JOP20200296A1 (ar) | 2013-06-10 | 2017-06-16 | Amgen Inc | عمليات صنع وأشكال بلورية من mdm2 مثبط |
CA2943363A1 (en) | 2014-04-02 | 2015-10-08 | Intermune, Inc. | Anti-fibrotic pyridinones |
US10703746B2 (en) | 2014-12-22 | 2020-07-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Mutant IDH1 inhibitors useful for treating cancer |
SG11201809297UA (en) * | 2016-04-26 | 2018-11-29 | H Lundbeck As | Use of an acetylcholinesterase inhibitor and idalopirdine for reducing falls in parkinson's disease patients |
US11364225B2 (en) * | 2019-08-21 | 2022-06-21 | Bn Intellectual Properties, Inc. | Pharmaceutical formulation for treating symptoms of migraine and cluster headaches, and method of using the same |
JPWO2023042887A1 (pl) * | 2021-09-15 | 2023-03-23 | ||
JPWO2023042888A1 (pl) * | 2021-09-15 | 2023-03-23 | ||
TW202404581A (zh) | 2022-05-25 | 2024-02-01 | 美商醫肯納腫瘤學公司 | Mek抑制劑及其用途 |
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IT1304904B1 (it) * | 1998-09-11 | 2001-04-05 | Eisai Co Ltd | Derivati anticolinesterasici per il trattamento delle sindromidolorose funzionali e/o organiche |
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ATE345803T1 (de) * | 2000-03-03 | 2006-12-15 | Eisai Co Ltd | Neue methoden unter verwendung von cholinesteraseinhibitoren |
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PT1300396E (pt) * | 2000-06-12 | 2009-04-20 | Eisai R&D Man Co Ltd | Compostos de 1,2-di-hidropiridina, processos para a sua preparação e sua utilização |
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JP4208512B2 (ja) * | 2002-07-23 | 2009-01-14 | 株式会社クラレ | 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法 |
JP2004189706A (ja) * | 2002-12-13 | 2004-07-08 | Eisai Co Ltd | 高度アルツハイマー型痴呆治療剤 |
MY148809A (en) * | 2004-07-06 | 2013-05-31 | Eisai R&D Man Co Ltd | Crystals of 1,2-dihydropyridine compound and their production process |
ME01224B (me) * | 2005-04-04 | 2013-06-20 | Eisai R&D Man Co Ltd | Jedinjenja dihidropiridina za liječenje neurodegenerativnih bolesti i demencije |
-
2006
- 2006-04-04 ME MEP-2011-133A patent/ME01224B/me unknown
- 2006-04-04 JP JP2008505418A patent/JP2008537552A/ja not_active Withdrawn
- 2006-04-04 RS RS20110318A patent/RS51822B/en unknown
- 2006-04-04 DK DK06740387.3T patent/DK1871368T3/da active
- 2006-04-04 PT PT06740387T patent/PT1871368E/pt unknown
- 2006-04-04 US US11/396,555 patent/US20060270709A1/en not_active Abandoned
- 2006-04-04 EP EP06749149A patent/EP1871369A4/en not_active Withdrawn
- 2006-04-04 WO PCT/US2006/012284 patent/WO2006107859A2/en active Application Filing
- 2006-04-04 PL PL06740387T patent/PL1871368T3/pl unknown
- 2006-04-04 CA CA002603258A patent/CA2603258A1/en not_active Abandoned
- 2006-04-04 AT AT06740387T patent/ATE511843T1/de active
- 2006-04-04 KR KR1020077025426A patent/KR20080007233A/ko not_active Application Discontinuation
- 2006-04-04 AU AU2006232517A patent/AU2006232517A1/en not_active Abandoned
- 2006-04-04 US US11/887,729 patent/US20090131480A1/en not_active Abandoned
- 2006-04-04 JP JP2008505417A patent/JP5180816B2/ja not_active Expired - Fee Related
- 2006-04-04 WO PCT/US2006/012285 patent/WO2006107860A2/en active Application Filing
- 2006-04-04 US US11/396,621 patent/US20060276510A1/en not_active Abandoned
- 2006-04-04 EP EP06740387A patent/EP1871368B1/en active Active
-
2007
- 2007-10-07 IL IL186412A patent/IL186412A0/en unknown
-
2011
- 2011-07-12 HR HR20110524T patent/HRP20110524T1/hr unknown
- 2011-07-29 CY CY20111101013T patent/CY1112427T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2006107859A8 (en) | 2007-11-08 |
EP1871368A4 (en) | 2009-11-11 |
EP1871369A2 (en) | 2008-01-02 |
RS51822B (en) | 2012-02-29 |
AU2006232517A1 (en) | 2006-10-12 |
EP1871368A2 (en) | 2008-01-02 |
US20090131480A1 (en) | 2009-05-21 |
CA2603258A1 (en) | 2006-10-12 |
WO2006107859A3 (en) | 2009-04-09 |
WO2006107860A2 (en) | 2006-10-12 |
US20060270709A1 (en) | 2006-11-30 |
EP1871368B1 (en) | 2011-06-08 |
JP2008537552A (ja) | 2008-09-18 |
JP5180816B2 (ja) | 2013-04-10 |
EP1871369A4 (en) | 2009-11-11 |
DK1871368T3 (da) | 2011-09-19 |
US20060276510A1 (en) | 2006-12-07 |
CY1112427T1 (el) | 2015-12-09 |
WO2006107859A2 (en) | 2006-10-12 |
ATE511843T1 (de) | 2011-06-15 |
HRP20110524T1 (hr) | 2011-08-31 |
ME01224B (me) | 2013-06-20 |
IL186412A0 (en) | 2008-08-07 |
KR20080007233A (ko) | 2008-01-17 |
WO2006107860A3 (en) | 2009-04-09 |
PT1871368E (pt) | 2011-08-30 |
JP2008538216A (ja) | 2008-10-16 |
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