PL172241B1 - Nowe bifenylo-podstawione pochodne chinoliny PL PL - Google Patents

Nowe bifenylo-podstawione pochodne chinoliny PL PL

Info

Publication number
PL172241B1
PL172241B1 PL93297713A PL29771393A PL172241B1 PL 172241 B1 PL172241 B1 PL 172241B1 PL 93297713 A PL93297713 A PL 93297713A PL 29771393 A PL29771393 A PL 29771393A PL 172241 B1 PL172241 B1 PL 172241B1
Authority
PL
Poland
Prior art keywords
acid
compound
biphenyl
oxy
pharmaceutically acceptable
Prior art date
Application number
PL93297713A
Other languages
English (en)
Polish (pl)
Other versions
PL297713A1 (en
Inventor
Denis E Ryono
John Lloyd
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of PL297713A1 publication Critical patent/PL297713A1/xx
Publication of PL172241B1 publication Critical patent/PL172241B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL93297713A 1992-02-14 1993-02-12 Nowe bifenylo-podstawione pochodne chinoliny PL PL PL172241B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83778292A 1992-02-14 1992-02-14

Publications (2)

Publication Number Publication Date
PL297713A1 PL297713A1 (en) 1993-08-23
PL172241B1 true PL172241B1 (pl) 1997-08-29

Family

ID=25275409

Family Applications (1)

Application Number Title Priority Date Filing Date
PL93297713A PL172241B1 (pl) 1992-02-14 1993-02-12 Nowe bifenylo-podstawione pochodne chinoliny PL PL

Country Status (16)

Country Link
EP (1) EP0556060A1 (enExample)
JP (1) JPH05286939A (enExample)
KR (1) KR930017891A (enExample)
CN (1) CN1044243C (enExample)
AU (1) AU656454B2 (enExample)
CA (1) CA2089185A1 (enExample)
FI (1) FI930621A7 (enExample)
HU (1) HU217627B (enExample)
IL (1) IL104623A (enExample)
MX (1) MX9300742A (enExample)
NO (1) NO930520L (enExample)
NZ (1) NZ245757A (enExample)
PL (1) PL172241B1 (enExample)
RU (1) RU2122540C1 (enExample)
TW (1) TW297025B (enExample)
ZA (1) ZA93531B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5767129A (en) * 1995-08-24 1998-06-16 Warner-Lambert Company Substituted quinolines and isoquinolines as calcium channel blockers, their preparation and the use thereof
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
DE60215139T2 (de) 2001-01-26 2007-08-16 Chugai Seiyaku K.K. Malonyl coa-decarboxylase inhibitoren als stoffwechselmodulatoren
ATE509014T1 (de) 2001-01-26 2011-05-15 Chugai Pharmaceutical Co Ltd Malonyl coa-decarboxylase inhibitoren als stoffwechselmodulatoren
EP1353662B1 (en) 2001-01-26 2007-04-18 Chugai Seiyaku Kabushiki Kaisha Methods for the treatment of diseases using malonyl-coa decarbox ylase inhibitors
JP4155351B2 (ja) 2001-02-20 2008-09-24 中外製薬株式会社 代謝調節剤として有用なマロニル−CoA脱炭酸酵素阻害剤としてのアゾール
US7709510B2 (en) 2001-02-20 2010-05-04 Chugai Seiyaku Kabushiki Kaisha Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
RU2201753C1 (ru) * 2002-03-12 2003-04-10 Нестерук Владимир Викторович Фармацевтическая композиция, обладающая диуретическим, дегидратирующим и гипотензивным действием
PE20040950A1 (es) * 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
JP4727579B2 (ja) 2003-08-01 2011-07-20 中外製薬株式会社 マロニル−CoAデカルボキシラーゼ阻害剤として有用なシアノアミド化合物
EP1653957B1 (en) 2003-08-01 2008-07-09 Chugai Seiyaku Kabushiki Kaisha Piperidine compounds useful as malonyl-coa decarboxylase inhibitors
EP2208495B1 (en) 2003-08-01 2011-12-14 Chugai Seiyaku Kabushiki Kaisha Cyanoguanidine-based azole compounds useful as malonyl-CoA decarboxylase inhibitors
DE602004030017D1 (de) 2003-08-01 2010-12-23 Chugai Pharmaceutical Co Ltd Heterocyclische verbindungen als nützliche malonyl-coa decarboxylase-hemmer
TWI374883B (en) * 2004-08-16 2012-10-21 Theravance Inc Crystalline form of a biphenyl compound
GB0519969D0 (en) * 2005-09-30 2005-11-09 Argenta Discovery Ltd Quinoline compounds
DK1928457T3 (da) 2005-09-30 2013-02-04 Pulmagen Therapeutics Asthma Ltd Quinoliner og deres terapeutiske anvendelse
SI2139881T1 (sl) * 2007-04-04 2012-05-31 Pulmagen Therapeutics Asthma Ltd Kinolini in njihova terapevtska raba

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
IE903911A1 (en) * 1989-11-20 1991-05-22 Ici Plc Diazine derivatives
US5049565A (en) * 1990-12-07 1991-09-17 Merck & Co., Inc. Microbial transformation process for preparing anti-hypertensive products
GB9102727D0 (en) * 1991-02-08 1991-03-27 Ici Plc Pharmaceutical agent
US5157040A (en) * 1991-04-05 1992-10-20 Merck & Co., Inc. Substituted quinolines as angiotensin ii antagonists

Also Published As

Publication number Publication date
ZA93531B (en) 1993-08-26
EP0556060A1 (en) 1993-08-18
NO930520D0 (no) 1993-02-12
PL297713A1 (en) 1993-08-23
NZ245757A (en) 1995-09-26
MX9300742A (es) 1993-09-01
CN1075720A (zh) 1993-09-01
IL104623A0 (en) 1993-06-10
TW297025B (enExample) 1997-02-01
KR930017891A (ko) 1993-09-20
HUT69694A (en) 1995-09-28
AU656454B2 (en) 1995-02-02
CA2089185A1 (en) 1993-08-15
CN1044243C (zh) 1999-07-21
JPH05286939A (ja) 1993-11-02
FI930621A7 (fi) 1993-08-15
FI930621A0 (fi) 1993-02-12
NO930520L (no) 1993-08-16
IL104623A (en) 1996-12-05
HU217627B (hu) 2000-03-28
AU3299193A (en) 1993-08-19
HU9300386D0 (en) 1993-04-28
RU2122540C1 (ru) 1998-11-27

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