PL1660484T3 - Metyloindole i metylopirolopirydyny jako agoniści receptora adrenergicznego α-1 - Google Patents
Metyloindole i metylopirolopirydyny jako agoniści receptora adrenergicznego α-1Info
- Publication number
- PL1660484T3 PL1660484T3 PL04739120T PL04739120T PL1660484T3 PL 1660484 T3 PL1660484 T3 PL 1660484T3 PL 04739120 T PL04739120 T PL 04739120T PL 04739120 T PL04739120 T PL 04739120T PL 1660484 T3 PL1660484 T3 PL 1660484T3
- Authority
- PL
- Poland
- Prior art keywords
- sup
- methyl
- alpha
- pyrrolopyridines
- adrenergic agonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Gynecology & Obstetrics (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46925503P | 2003-05-09 | 2003-05-09 | |
EP04739120A EP1660484B1 (en) | 2003-05-09 | 2004-04-30 | Methyl indoles and methyl pyrrolopyridines as alpha-1 adrenergic agonists |
PCT/EP2004/004609 WO2004099189A1 (en) | 2003-05-09 | 2004-04-30 | Methyl indoles and methyl pyrrolopyridines as alph-1 adrenergic agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1660484T3 true PL1660484T3 (pl) | 2009-02-27 |
Family
ID=33435226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL04739120T PL1660484T3 (pl) | 2003-05-09 | 2004-04-30 | Metyloindole i metylopirolopirydyny jako agoniści receptora adrenergicznego α-1 |
Country Status (15)
Country | Link |
---|---|
US (1) | US6979696B2 (pl) |
EP (1) | EP1660484B1 (pl) |
JP (1) | JP4454622B2 (pl) |
KR (1) | KR100751163B1 (pl) |
CN (1) | CN100378097C (pl) |
AT (1) | ATE406363T1 (pl) |
AU (1) | AU2004235923B2 (pl) |
BR (1) | BRPI0410237A (pl) |
CA (1) | CA2523253C (pl) |
DE (1) | DE602004016177D1 (pl) |
ES (1) | ES2313019T3 (pl) |
MX (1) | MXPA05011841A (pl) |
PL (1) | PL1660484T3 (pl) |
RU (1) | RU2313524C2 (pl) |
WO (1) | WO2004099189A1 (pl) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20050072812A (ko) * | 2002-11-07 | 2005-07-12 | 악조 노벨 엔.브이. | 안드로겐-수용체와 관련된 질병의 치료에 효과적인 인돌 |
TW200602317A (en) * | 2004-04-23 | 2006-01-16 | Akzo Nobel Nv | Novel androgens |
JP2009510066A (ja) * | 2005-09-29 | 2009-03-12 | ワイス | 血管運動症状(vms)の治療のためのモノアミン再取り込みのモジュレータである1−(1h−インドール−1−イル)−3−(メチルアミノ)−1−フェニルプロパン−2−オール誘導体および関連の化合物 |
ATE442368T1 (de) * | 2005-11-30 | 2009-09-15 | Hoffmann La Roche | 3-amino-2-arylpropylazaindole und anwendungen davon |
HUE030393T2 (en) | 2010-12-28 | 2017-05-29 | Sanofi Sa | New pyrimidine derivatives, a process for their preparation, and their pharmaceutical use as inhibitors of AKT (PKB) phosphorylation |
CN102702196B (zh) * | 2012-06-13 | 2015-01-14 | 南京药石药物研发有限公司 | 3-甲基-7-氮杂吲哚的合成方法 |
KR102129842B1 (ko) * | 2013-10-02 | 2020-07-06 | 주식회사 대웅제약 | 술포닐인돌 유도체 및 이의 제조방법 |
WO2016014426A1 (en) * | 2014-07-21 | 2016-01-28 | The Arizona Board Of Regents | Organic reactions |
WO2024080361A1 (ja) * | 2022-10-14 | 2024-04-18 | 株式会社 三和化学研究所 | イミダゾール誘導体 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3370063A (en) * | 1964-10-05 | 1968-02-20 | Mcneilab Inc | Substituted dimethoxy indoles and method of making the same |
US3586695A (en) * | 1968-01-26 | 1971-06-22 | Dow Chemical Co | Substituted imidazolinyl indoles |
GB9011335D0 (en) | 1990-05-21 | 1990-07-11 | Fujisawa Pharmaceutical Co | Indolebutyric acid derivatives and process for preparation thereof |
CA2164009A1 (en) | 1993-06-14 | 1994-12-22 | Robert L. Dow | Secondary amines as antidiabetic and antiobesity agents |
JPH0887346A (ja) * | 1994-09-14 | 1996-04-02 | Chino Kogyo:Kk | パソコン等デスク上を活用する為の卓上台座器具 |
CN1237160A (zh) | 1996-11-14 | 1999-12-01 | 辉瑞大药厂 | 取代的吡啶的制备方法 |
SG72827A1 (en) * | 1997-06-23 | 2000-05-23 | Hoffmann La Roche | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives |
GB9910110D0 (en) * | 1999-04-30 | 1999-06-30 | Glaxo Group Ltd | Chemical compounds |
WO2001070687A1 (de) | 2000-03-23 | 2001-09-27 | Bayer Aktiengesellschaft | Indole zur behandlung von krankheiten die mit schilddrüsenhormonen behandeln werden können |
DE10106214A1 (de) * | 2001-02-10 | 2002-08-14 | Boehringer Ingelheim Pharma | Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz |
BR0307406A (pt) * | 2002-02-01 | 2004-12-28 | Hoffmann La Roche | Indóis substituìdos como agonistas alfa-1 |
-
2004
- 2004-04-30 EP EP04739120A patent/EP1660484B1/en not_active Expired - Lifetime
- 2004-04-30 ES ES04739120T patent/ES2313019T3/es not_active Expired - Lifetime
- 2004-04-30 DE DE602004016177T patent/DE602004016177D1/de not_active Expired - Lifetime
- 2004-04-30 PL PL04739120T patent/PL1660484T3/pl unknown
- 2004-04-30 CA CA2523253A patent/CA2523253C/en not_active Expired - Fee Related
- 2004-04-30 WO PCT/EP2004/004609 patent/WO2004099189A1/en active IP Right Grant
- 2004-04-30 BR BRPI0410237-1A patent/BRPI0410237A/pt not_active IP Right Cessation
- 2004-04-30 MX MXPA05011841A patent/MXPA05011841A/es active IP Right Grant
- 2004-04-30 AU AU2004235923A patent/AU2004235923B2/en not_active Ceased
- 2004-04-30 KR KR1020057021188A patent/KR100751163B1/ko not_active IP Right Cessation
- 2004-04-30 RU RU2005138143/04A patent/RU2313524C2/ru not_active IP Right Cessation
- 2004-04-30 JP JP2006505343A patent/JP4454622B2/ja not_active Expired - Fee Related
- 2004-04-30 AT AT04739120T patent/ATE406363T1/de active
- 2004-04-30 CN CNB2004800122944A patent/CN100378097C/zh not_active Expired - Fee Related
- 2004-05-07 US US10/841,288 patent/US6979696B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2313019T3 (es) | 2009-03-01 |
KR100751163B1 (ko) | 2007-08-22 |
RU2313524C2 (ru) | 2007-12-27 |
WO2004099189A1 (en) | 2004-11-18 |
AU2004235923B2 (en) | 2008-01-24 |
DE602004016177D1 (de) | 2008-10-09 |
CN1784397A (zh) | 2006-06-07 |
CA2523253A1 (en) | 2004-11-18 |
MXPA05011841A (es) | 2006-01-26 |
RU2005138143A (ru) | 2006-08-10 |
AU2004235923A1 (en) | 2004-11-18 |
KR20060015590A (ko) | 2006-02-17 |
CN100378097C (zh) | 2008-04-02 |
EP1660484A1 (en) | 2006-05-31 |
ATE406363T1 (de) | 2008-09-15 |
BRPI0410237A (pt) | 2006-05-09 |
CA2523253C (en) | 2010-06-22 |
US6979696B2 (en) | 2005-12-27 |
JP4454622B2 (ja) | 2010-04-21 |
US20040224973A1 (en) | 2004-11-11 |
JP2006525970A (ja) | 2006-11-16 |
EP1660484B1 (en) | 2008-08-27 |
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