PL1644351T3 - Pochodne imidazolu i ich zastosowanie w leczeniu zaburzeń mediowanych przez receptor mGluR5 - Google Patents

Pochodne imidazolu i ich zastosowanie w leczeniu zaburzeń mediowanych przez receptor mGluR5

Info

Publication number
PL1644351T3
PL1644351T3 PL04740542T PL04740542T PL1644351T3 PL 1644351 T3 PL1644351 T3 PL 1644351T3 PL 04740542 T PL04740542 T PL 04740542T PL 04740542 T PL04740542 T PL 04740542T PL 1644351 T3 PL1644351 T3 PL 1644351T3
Authority
PL
Poland
Prior art keywords
treatment
imidazole derivatives
receptor mediated
mediated disorders
mglur5 receptor
Prior art date
Application number
PL04740542T
Other languages
English (en)
Inventor
Bernd Buettelmann
Simona Maria Ceccarelli
Georg Jaeschke
Sabine Kolczewski
Richard Hugh Philip Porter
Eric Vieira
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL1644351T3 publication Critical patent/PL1644351T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL04740542T 2003-07-03 2004-07-01 Pochodne imidazolu i ich zastosowanie w leczeniu zaburzeń mediowanych przez receptor mGluR5 PL1644351T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03014512 2003-07-03
EP04740542A EP1644351B1 (en) 2003-07-03 2004-07-01 Imidazole derivatives and their use in the treatment of mGluR5 receptor mediated disorders
PCT/EP2004/007177 WO2005003117A1 (en) 2003-07-03 2004-07-01 Imidazole derivatives iii

Publications (1)

Publication Number Publication Date
PL1644351T3 true PL1644351T3 (pl) 2008-08-29

Family

ID=33560749

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04740542T PL1644351T3 (pl) 2003-07-03 2004-07-01 Pochodne imidazolu i ich zastosowanie w leczeniu zaburzeń mediowanych przez receptor mGluR5

Country Status (27)

Country Link
US (1) US7091222B2 (pl)
EP (1) EP1644351B1 (pl)
JP (1) JP4571631B2 (pl)
KR (1) KR100719653B1 (pl)
CN (1) CN100562520C (pl)
AR (1) AR044973A1 (pl)
AT (1) ATE388145T1 (pl)
AU (1) AU2004253657B2 (pl)
BR (1) BRPI0412158A (pl)
CA (1) CA2531210C (pl)
CO (1) CO5660258A2 (pl)
DE (1) DE602004012268T2 (pl)
DK (1) DK1644351T3 (pl)
ES (1) ES2300789T3 (pl)
HR (1) HRP20080173T3 (pl)
IL (1) IL172821A (pl)
MX (1) MXPA06000193A (pl)
MY (1) MY142085A (pl)
NO (1) NO20060112L (pl)
NZ (1) NZ544454A (pl)
PL (1) PL1644351T3 (pl)
PT (1) PT1644351E (pl)
RU (1) RU2360911C2 (pl)
SI (1) SI1644351T1 (pl)
TW (1) TWI252849B (pl)
WO (1) WO2005003117A1 (pl)
ZA (1) ZA200600026B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA80888C2 (en) * 2003-06-05 2007-11-12 Hoffmann La Roche Imidazole derivatives as glutmate receptor antagonists
US7452909B2 (en) * 2003-09-04 2008-11-18 Hoffman-La Roche Inc. Imidazole derivatives
HRP20080363T3 (hr) * 2004-06-01 2008-09-30 F. Hoffmann - La Roche Ag Piridin-4-il-etinil-imidazoli i pirazoli kao antagonisti mglu5 receptora
PL1756086T3 (pl) * 2004-06-01 2008-11-28 Hoffmann La Roche Pirydyn-4-ylo-etynylo-imidazole i pirazole jako antagoniści receptora mGlu5
US20060173048A1 (en) * 2005-02-03 2006-08-03 Mcarthur Silvia G Imidazole derivatives
DE102005062987A1 (de) * 2005-12-28 2007-07-05 Grünenthal GmbH Substituierte Propiolsäureamide und ihre Verwendung zur Herstellung von Arzneimitteln
MY148217A (en) * 2006-12-21 2013-03-29 Hoffmann La Roche Polymorphs of a mglur5 receptor antagonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US304910A (en) * 1884-09-09 Robeet h
US4882343A (en) * 1987-08-28 1989-11-21 G. D. Searle & Co. Biarylalkylimidazole derivatives as anti-depressants
TW544448B (en) * 1997-07-11 2003-08-01 Novartis Ag Pyridine derivatives
US7531529B2 (en) * 2003-06-05 2009-05-12 Roche Palo Alto Llc Imidazole derivatives

Also Published As

Publication number Publication date
WO2005003117A1 (en) 2005-01-13
ES2300789T3 (es) 2008-06-16
MXPA06000193A (es) 2006-04-11
EP1644351B1 (en) 2008-03-05
AU2004253657A1 (en) 2005-01-13
IL172821A0 (en) 2006-06-11
CA2531210A1 (en) 2005-01-13
CN1823054A (zh) 2006-08-23
JP2009500291A (ja) 2009-01-08
ATE388145T1 (de) 2008-03-15
DK1644351T3 (da) 2008-06-23
DE602004012268T2 (de) 2009-03-12
NZ544454A (en) 2008-08-29
ZA200600026B (en) 2007-05-30
RU2360911C2 (ru) 2009-07-10
IL172821A (en) 2011-01-31
AR044973A1 (es) 2005-10-12
PT1644351E (pt) 2008-04-21
BRPI0412158A (pt) 2006-08-22
SI1644351T1 (sl) 2008-06-30
TW200514779A (en) 2005-05-01
US20050009878A1 (en) 2005-01-13
CO5660258A2 (es) 2006-07-31
HRP20080173T3 (hr) 2008-06-30
KR20060029677A (ko) 2006-04-06
RU2006103009A (ru) 2006-08-27
CA2531210C (en) 2012-05-29
KR100719653B1 (ko) 2007-05-18
US7091222B2 (en) 2006-08-15
CN100562520C (zh) 2009-11-25
AU2004253657B2 (en) 2009-09-03
MY142085A (en) 2010-08-30
EP1644351A1 (en) 2006-04-12
NO20060112L (no) 2006-01-24
DE602004012268D1 (de) 2008-04-17
TWI252849B (en) 2006-04-11
JP4571631B2 (ja) 2010-10-27

Similar Documents

Publication Publication Date Title
SI1599467T1 (sl) Novi cianopiridinski derivati uporabni pri zdravljenju raka in drugih motenj
IL189578A0 (en) Pyridine derivatives and their use in the treatment of psychotic disorders
ZA200705123B (en) Rapamycin derivatives and the uses thereof in the treatment of neurological disorders
IL183654A0 (en) Fused pyrazole derivatives and uses thereof in methods of treatment of metabolic-related disorders
TWI349551B (en) Thiophenepyrimidinone derivatives and their use in therapy
IL181706A0 (en) The treatment of inflammatory disorders and pain
IL183656A0 (en) Indenyl derivatives and use thereof for the treatment of neurological disorders
ZA200410409B (en) Use of thio-oxindole derivatives in treatment of hormonerelated conditions
IL162678A0 (en) N-pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases
IL177369A0 (en) Pyrimidine derivatives for use as vanilloid receptor ligands and their use in the treatment of pain
IL195900A0 (en) Piperazinyl derivatives useful in the treatment of gpr38 receptor mediated diseases
ZA200410401B (en) Use of thio-oxindole derivatives in treatment of skin disorders
PL2163248T3 (pl) Pochodne benzotiazepiny jako inhibitory receptora rianodynowego (RYR2) i ich zastosowanie w leczeniu chorób serca
SI1644351T1 (sl) Derivati imidazola in uporaba v zdravljenju motenj povezanih s mglur5 receptorjem
AU2003250831A8 (en) Use of hec1 antagonists in the treatment of proliferative disorders and cancer
IL162941A0 (en) Carboxamidine derivatives and their use in the treatment of vascular diseases
EP1812009A4 (en) GABA-STEROID ANTAGONISTS AND THEIR USE FOR THE TREATMENT OF DISEASES OF THE CNS
PL375793A1 (pl) 2-Tio-podstawione pochodne imidazolu i ich zastosowanie w farmacji
PT1680405E (pt) Derivados de bengamida e sua utilização para o tratamento de doenças cancerosas
GB0419828D0 (en) The treatment of inflammatroy disorders and pain
AU2003245995A8 (en) Use of gaba-c receptor antagonists for the treatment of myopia
ZA200704412B (en) Indenyl derivatives and use thereof for the treatment of neurological disorders
ZA200801548B (en) Pyridine derivatives and their use in the treatment of psychotic disorders
HK1118826A (en) Pyridine derivatives and their use in the treatment of psychotic disorders
HRP20041212A2 (en) Use of vasopeptidase inhibitors in the treatment of nephropathy